Lisbeth Høier Olsen

2019

¹⁸F-FDG PET/MR-imaging in a Göttingen Minipig model of atherosclerosis: Correlations with histology and quantitative gene expression

Ludvigsen, T. P., Pedersen, S. F., Vegge, A., Ripa, R. S., Johannesen, H. H., Hansen, A. E., Löfgren, J., Schumacher-Petersen, C., Kirk, R. K., Pedersen, H. D., Christoffersen, B. Ø., Ørbæk, M., Forman, J. L., Klausen, T. L., Olsen, L. H. & Kjaer, A., Jun 2019, In: Atherosclerosis. 285, p. 55-63 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Analytical validation of a conventional cardiac troponin I assay for dogs and cats

Langhorn, R., Yrfelt, J. D., Stjernegaard, C. S., Christiansen, L. B., Olsen, L. H. & Nielsen, L. N., Mar 2019, In: Veterinary Clinical Pathology. p. 36-41

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Experimental non-alcoholic steatohepatitis in Göttingen Minipigs: Consequences of high fat-fructose-cholesterol diet and diabetes

Schumacher-Petersen, C., Christoffersen, B. O., Kirk, R. K., Ludvigsen, T. P., Zois, N. E., Pedersen, H. D., Vyberg, M. & Olsen, L. H., 2019, In: Journal of Translational Medicine. 17, 1, 110.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

42 Downloads (Pure)

Hyperglycemia-induced transcriptional regulation of ROCK1 and TGM2 expression is involved in small artery remodeling in obese diabetic Göttingen Minipigs

Ludvigsen, T. P., Olsen, L. H., Petersen, H. D., Østergaard Christoffersen, B. & Jensen, L. J., 12 Dec 2019, (Accepted/In press) In: Clinical Science.

Research output: Contribution to journal › Journal article › Research › peer-review

Myxømatøs mitralklapsygdom hos hund: Medicinsk behandling

Reimann, M. J., Christiansen, L. B., Falk, B. T. & Olsen, L. H., 2019, In: Dansk Veterinaertidsskrift. 2019, 11, p. 38-43

Research output: Contribution to journal › Journal article › Research › peer-review

2 Downloads (Pure)

Myxømatøs mitralklapsygdom hos hund: Metoder til diagnostik af behandlingskrævende sygdomsstadier

Reimann, M. J., Christiansen, L. B., Falk, T. & Olsen, L. H., 2019, In: Dansk Veterinaertidsskrift. 2019, 9, p. 28-32

Research output: Contribution to journal › Review › peer-review

16 Downloads (Pure)

Urine 5-hydroxyindoleacetic acid in Cavalier King Charles spaniels with preclinical myxomatous mitral valve disease

Christiansen, L. B., Cremer, S. E., Helander, A., Madsen, T., Reimann, M. J., Møller, J. E., Höglund, K., Ljungvall, I., Häggström, J. & Olsen, L. H., 2019, In: Veterinary Journal. 250, p. 36-43 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

2018

Abrogating fibrinolysis does not improve bleeding or rFVIIa/rFVIII treatment in a non-mucosal venous injury model in haemophilic rodents

Stagaard, R., Flick, M. J., Bojko, B., Goryński, K., Goryńska, P. Z., Ley, C. D., Olsen, L. H. & Knudsen, T., 2018, In: Journal of Thrombosis and Haemostasis. 16, 7, p. 1369-1382 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice

Stagaard, R., Ley, C. D., Almholt, K., Olsen, L. H., Knudsen, T. & Flick, M. J., 27 Nov 2018, In: Blood advances. 2, 22, p. 3126-3136 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Angiotensin-converting enzyme activity in Cavalier King Charles Spaniels with an ACE gene polymorphism and myxomatous mitral valve disease

Meurs, K. M., Olsen, L. H., Reimann, M. J., Keene, B. W., Atkins, C. E., Adin, D., Aona, B., Condit, J., Defrancesco, T., Reina-Doreste, Y., Stern, J. A., Tou, S., Ward, J. & Woodruff, K., 2018, In: Pharmacogenetics and Genomics. 28, 2, p. 37-40 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Cardiac procholecystokinin expression during haemodynamic changes in the mammalian heart

Goetze, J. P., Hunter, I., Zois, N. E., Terzic, D., Valeur, N., Olsen, L. H., Smith, J., Plomgaard, P., Hansen, L. H., Rehfeld, J. F., Balling, L. & Gustafsson, F., Oct 2018, In: Peptides. 108, p. 7-13 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity

Andreasen, L. J., Krog, S., Ludvigsen, T. P., Nielsen, O. L., Møller, J. E., Christoffersen, B. Ø., Pedersen, H. D. & Olsen, L. H., 2018, In: Nutrition and Metabolism. 15, 64.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

68 Downloads (Pure)

SK channel inhibition did not increase short-term variability of the QT intervals in atrial tachypaced pigs with left ventricular dysfunction in contrast to the positive control dofetilide

Citerni, C., Kirchhoff, J., Olsen, L., Gentilini, F., Forni, M., Zannoni, A., Edvardsson, N., Bentzen, B., Grunnet, M. & Diness, J., 2018, In: European Heart Journal. 39, S1, p. 809-809 P3811.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Structural remodeling in cerebral and mesenteric arteries from obese Göttingen minipigs with or without diabetes

Ludvigsen, T. P., Olsen, L. H., Pedersen, H. D., Østergaard Christoffersen, B. & Jensen, L. J., 13 Sept 2018, p. 467P-468P . 2 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

2017

A porcine subcutaneous Staphylococcus aureus abscess model - a pilot study

Nielsen, O. L., Larsen, M. N., Frees, D., Pedersen, M. M., Skov, S. & Olsen, L. H., 2017.

Research output: Contribution to conference › Conference abstract for conference › Communication

Markers of Oxidative Stress in Dogs with Myxomatous Mitral Valve Disease are Influenced by Sex, Neuter Status, and Serum Cholesterol Concentration

Reimann, M. J., Haggstrom, J., Moller, J. E., Lykkesfeldt, J., Falk, T. & Olsen, L. H., 1 Mar 2017, In: Journal of Veterinary Internal Medicine. 31, 2, p. 295-302 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

112 Downloads (Pure)

Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels

Reimann, M. J., Moller, J. E., Haggstrom, J., Martinussen, T., Zatrazemi, S. S. C., Svanholm, L., Nielsen, L. B. M., Pedersen, H. D. & Olsen, L. H., 1 Jul 2017, In: Journal of Veterinary Internal Medicine. 31, 4, p. 1008-1016 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

104 Downloads (Pure)

2016

Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings

Madsen, M. F., Kanters, J. K., Pedersen, P. J., Haugaard, M. M., Carstensen, H., Olsen, L. H. & Buhl, R., 28 Nov 2016, In: BMC Veterinary Research. 12, 10 p., 266.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

121 Downloads (Pure)

Breeding Restrictions Decrease the Prevalence of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels over an 8-to 10-Year Period

Birkegård, A. C., Reimann, M. J., Martinussen, T., Haggstrom, J., Pedersen, H. D. & Olsen, L. H., 1 Jan 2016, In: Journal of Veterinary Internal Medicine. 30, 1, p. 63-68 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

117 Downloads (Pure)

Changes in heart rate, arrhythmia frequency, and cardiac biomarker values in horses during recovery after a long-distance endurance ride

Madsen, M. F., Kanters, J. K., Haugaard, M. M., Pedersen, P. J., Carstensen, H., Balling, J. D., Olsen, L. H. & Buhl, R., 1 May 2016, In: Journal of the American Veterinary Medical Association. 248, 9, p. 1034-1042 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Increased serum C-reactive protein concentrations in dogs with congestive heart failure due to myxomatous mitral valve disease

Reimann, M. J., Ljungvall, I., Hillstrom, A., Møller, J. E., Hagman, R., Falk, T., Hoglund, K., Haggstrom, J. & Olsen, L. H., 1 Mar 2016, In: Veterinary Journal. 209, p. 113-118

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes

Flethøj, M., Schwarzwald, C. C., Haugaard, M. M., Carstensen, H., Kanters, J. K., Olsen, L. H. & Buhl, R., 1 Jul 2016, In: Journal of Veterinary Internal Medicine. 30, 4, p. 1260-1269 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

96 Downloads (Pure)

2015

Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease

Cremer, S. E., Moesgaard, S. G., Rasmussen, C. E., Zois, N. E., Falk, T., Reimann, M. J., Cirera Salicio, S., Aupperle, H., Oyama, M. A. & Olsen, L. H., 1 Jun 2015, In: Research in Veterinary Science. 100, p. 197-206 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals

Ludvigsen, T. P., Kirk, R. K., Christoffersen, B. Ø., Pedersen, H. D., Martinussen, T., Kildegaard, J., Heegaard, P. M. H., Lykkesfeldt, J. & Olsen, L. H., 22 Sept 2015, In: Journal of Translational Medicine. 13, 12 p., 312.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

147 Downloads (Pure)

Plasma and serum serotonin concentrations and surface-bound platelet serotonin expression in Cavalier King Charles Spaniels with myxomatous mitral valve disease

Cremer, S. E., Kristensen, A. T., Reimann, M. J., Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, L. H., 1 Jun 2015, In: American Journal of Veterinary Research. 76, 6, p. 520-531 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Serotonin markers show altered transcription levels in an experimental pig model of mitral regurgitation

Cremer, S. E., Zois, N. E., Moesgaard, S. G., Ravn, N., Cirera Salicio, S., Honge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Leifsson, P. S., Falk, B. T., Oyama, M. A., Orton, C., Martinussen, T. & Olsen, L. H., 1 Feb 2015, In: The Veterinary Journal. 203, 2, p. 192-198 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Vascular gene expression in diet-induced atherosclerotic Gottingen minipigs

Blom, L. V. V., Skovgaard, K., Ludvigsen, T. P., Kirk, R. K., Christoffersen, B. O., Pedersen, H. D., Heegaard, P. M. & Olsen, L. H., Jul 2015, In: Atherosclerosis. 241, 1, p. E85-E85 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

2014

Associations between N-terminal procollagen type III, fibrosis and echocardiographic indices in dogs that died due to myxomatous mitral valve disease

Hezzell, M. J., Falk, B. T., Olsen, L. H., Boswood, A. & Elliott, J., 1 Dec 2014, In: Journal of Veterinary Cardiology. 16, 4, p. 257-264 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors

Reimann, M. J., Häggström, J., Mortensen, A., Lykkesfeldt, J., Møller, J. E., Falk, B. T. & Olsen, L. H., 1 Sept 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Canine mitral valve disease: From genetics through screening programs, to practical breeding advice

Häggström, J., Swift, S. & Olsen, L. H., 2014.

Research output: Contribution to conference › Conference abstract for conference › Communication

Cardiovascular of Inflammatory Disease Models: In vivo imaging, Pathology and Pharmacology

Olsen, L. H., Nielsen, O. L., Hunter, I., Falk, B. T., Cremer, S. E., Ludvigsen, T. P., Reimann, M. J., Olsen, H. G., Nielsen, K. M., Laursen, H., Kronborg, S. & Kjempff, C. T., 2014.

Research output: Contribution to conference › Poster › Communication

Development of left ventricular hypertrophy in a novel porcine model of mitral regurgitation

Ravn, N., Zois, N. E., Moesgaard, S. G., Hønge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Cremer, S. E. & Olsen, L. H., Jun 2014, In: Scandinavian Cardiovascular Journal. 48, 3, p. 189-195 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Echocardiographic assessment of left ventricular function in mitral regurgitation: is the dog a useful model of man?

Zois, N. E., Pedersen, H. D., Häggström, J. & Olsen, L. H., 2014, In: Cardiovascular Endocrinology. 3, 1, p. 9-14 6 p.

Research output: Contribution to journal › Review › peer-review

1 Citation (Scopus)

Feasibility of simultaneous PET/MR in diet-induced atherosclerotic minipig: a pilot study for translational imaging

Pedersen, S. F., Ludvigsen, T. P., Johannesen, H. H., Löfgren, J., Ripa, R. S., Hansen, A. E., Ettrup, A. J., Christoffersen, B. Ø., Pedersen, H. D., Olsen, L. H., Højgaard, L. & Kjær, A., 2014, In: American Journal of Nuclear Medicine and Molecular Imaging. 4, 5, p. 448-58 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs

Boonen, H. C. M., Moesgaard, S. G., Birck, M. M., Christoffersen, B. Ø., Cirera Salicio, S., Heegaard, P. M. H., Højbøge, T. R., Jensen, L. J., Mortensen, A., Olsen, L. H., Sheykhzade, M., Tang, J. & Lykkesfeldt, J., 18 Nov 2014, In: Pflügers ARchiv (European Journal of Physiology). 466, 12, p. 2167-2176 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

1756 Downloads (Pure)

High-level serotonin-binding in subpopulation of highly-activated platelets in Cavalier King Charles Spaniels with myxomateous valve disease

Cremer, S. E., Kristensen, A. T., Reimann, M. J., Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, L. H., 2014. 1 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

High-level serotonin binding in subpopulation of highly activated platelets in cavalier King charles spaniels with myxomatous mitral valve disease

Cremer, S. E., Kristensen, A. T., Reimann, M. J., Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, L. H., 2014.

Research output: Contribution to conference › Conference abstract for conference › Communication

Holter monitoring of small breed dogs with advanced myxomatous mitral valve disease with and without a history of syncope

Rasmussen, C. E., Falk, B. T., Petrič, A. D., Schaldemose, M., Zois, N. E., Moesgaard, S. G., Åblad, B., Nielsen, H. Y., Ljungvall, I., Höglund, K., Häggström, J., Pedersen, H. D., Bland, J. M. & Olsen, L. H., Mar 2014, In: Journal of Veterinary Internal Medicine. 28, 2, p. 363-370 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs) and transforming growth factor-β (TGF-β) in advanced canine myxomatous mitral valve disease

Moesgaard, S. G., Aupperle, H., Rajamäki, M. M., Falk, T., Rasmussen, C. E., Zois, N. E. & Olsen, L. H., 1 Dec 2014, In: Research in Veterinary Science. 97, 3, p. 560-567 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Natriuretic peptides in cardiometabolic regulation and disease

Zois, N. E., Bartels, E. D., Hunter, I., Kousholt, B. S., Olsen, L. H. & Gøtze, J. P., Jul 2014, In: Nature Reviews Cardiology. 11, 7, p. 403-412 10 p.

Research output: Contribution to journal › Review › peer-review

102 Citations (Scopus)

Noninvasive assessment of pulse-wave velocity and flow-mediated vasodilation in anesthetized Göttingen minipigs

Ludvigsen, T. P., Wiinberg, N., Jensen, C. J., Callesen, A. T., Andersen, R. W., Jørgensen, A. S. H., Christoffersen, B. Ø., Pedersen, H. D., Moesgaard, S. G. & Olsen, L. H., 1 Dec 2014, In: Comparative Medicine. 64, 6, p. 471-477 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Pig models for the human heart failure syndrome

Hunter, I., Terzic, D., Zois, N. E., Olsen, L. H. & Gøtze, J. P., 2014, In: Cardiovascular Endocrinology. 3, 1, p. 15-18 4 p.

Research output: Contribution to journal › Review › peer-review

1 Citation (Scopus)

Potassium and calcium channel gene expression in small arteries in porcine and rat models of diet-induced obesity (Poster)

Jensen, L. J., Salomonsson, M., Sørensen, C. M., von Holstein-Rathlou, N-H., Pedersen, H. D., Christoffersen, B. Ø., Olsen, L. H. & Ludvigsen, T. P., 27 Apr 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, Supplement 1, 1 p., 676.4.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

Reimann, M. J., Møller, J. E., Häggström, J., Markussen, B., Holen, A. E. W., Falk, B. T. & Olsen, L. H., Mar 2014, In: The Veterinary Journal. 199, 3, p. 348-354 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Serotonin concentration is elevated in platelet-rich plasma and left ventricular myocardial and mitral valve leaflet tissue in dogs with myxomatous mitral valve disease

Cremer, S. E., Singletary, G. E., Olsen, L. H., Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C. A., Pizzinat, N. & Oyama, M. A., 2014.

Research output: Contribution to conference › Conference abstract for conference › Communication

Serotonin concentrations in platelets, plasma, mitral valve leaflet, and left ventricular myocardial tissue in dogs with myxomatous mitral valve disease

Cremer, S. E., Singletary, G. E., Olsen, L. H., Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C. A., Pizzinat, N. & Oyama, M. A., 1 Sept 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1534-1540 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Strong association between activated valvular interstitial cells and histopathological lesions in porcine model of induced mitral regurgitation

Cremer, S. E., Zois, N. E., Moesgaard, S. G., Ravn, N., Cirera Salicio, S., Honge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Leifsson, P. S., Falk, B. T., Oyama, M. A., Orton, C., Martinussen, T. & Olsen, L. H., 15 Jun 2014, In: International Journal of Cardiology. 174, 2, p. 443-446 4 p.

Research output: Contribution to journal › Letter › peer-review

2 Citations (Scopus)

2013

Cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 hours of life in piglets

Smith, J., Christoffersen, C., Nørgaard, L. M., Olsen, L. H., Vejlstrup, N. G., Andersen, C. B. & Gøtze, J. P., 1 May 2013, In: Endocrinology. 154, 5, p. 1864-1872 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Cardiac troponin-I concentration, myocardial arteriosclerosis, and fibrosis in dogs with congestive heart failure because of Myxomatous Mitral Valve Disease

Falk, B. T., Ljungvall, I., Zois, N. E., Höglund, K., Olsen, L. H., Pedersen, H. D. & Häggström, J., May 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 500-506 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

Decreased Right Ventricular Systolic Function in Dogs with Myxomatous Mitral Valve Disease

Olsen, L. H., Reimann, M. J., Møller, J. E., Häggström, J., Jangdin, S. E., Falk, B. T., Uggla, T. & Zois, N. E., 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 628-629 2 p., C6.

Research output: Contribution to journal › Conference abstract in journal › Research

Lisbeth Høier Olsen

Research output

Search results