Lars Hviid

2008

CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression

Magistrado, P., Staalsoe, T., Theander, T., Hviid, L. & Jensen, A., 2008, In: Malaria Journal. 7, 1, p. 204

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

11 Downloads (Pure)

Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania

Vestergaard, L. S., Lusingu, J. P., Nielsen, M. A., Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, M., Bygbjerg, I. C., Lemnge, M. M., Staalsoe, T., Hviid, L. & Theander, T. G., 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Malaria vaccines: immunity, models and monoclonal antibodies

Hviid, L. & Barfod, L., 2008, In: Trends in Parasitology. 24, 9, p. 392-395 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes

Magistrado, P., Salanti, A., Tuikue Ndam, N. G., Mwakalinga, S. B., Resende, M., Dahlbäck, M., Hviid, L., Lusingu, J., Theander, T. G. & Nielsen, M. A., 2008, In: Journal of Infectious Diseases.

Research output: Contribution to journal › Journal article › Research › peer-review

47 Citations (Scopus)

2007

Adhesion specificities of Plasmodium falciparum-infected erythrocytes involved in the pathogenesis of pregnancy-associated malaria

Hviid, L., 2007, In: American Journal of Pathology. 170, 6, p. 1817-9 3 p.

Research output: Contribution to journal › Editorial › peer-review

2 Citations (Scopus)

Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

Dahlbäck, M., Lavstsen, T., Salanti, A., Hviid, L., Arnot, D. E., Theander, T. G. & Nielsen, M. A., 2007, In: Malaria Journal. 6, p. 78

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

Developing Plasmodium falciparum malaria vaccines for populations living in areas with stable parasite transmission

Hviid, L. & Theander, T. G., 2007, In: International Journal of Biotechnology. 9, 3/4, p. 292-300 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Development of vaccines against Plasmodium falciparum malaria: taking lessons from naturally acquired protective immunity

Hviid, L., 2007, In: Microbes and Infection. 9, 6, p. 772-6 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

Barfod, L., Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, A., Ofori, M. F., Turner, L., Resende, M., Nielsen, M. A., Theander, T. G., Sallusto, F., Lanzavecchia, A. & Hviid, L., 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

76 Citations (Scopus)

Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria

Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, T., Turner, L., Hviid, L., Jensen, A. T. R. & Theander, T. G., 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

Malaria in pregnancy: pathogenesis and immunity

Rogerson, S. J., Hviid, L., Duffy, P. E., Leke, R. F. G. & Taylor, D. W., 2007, In: Lancet Infectious Diseases. 7, 2, p. 105-17 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

353 Citations (Scopus)

Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin

Nielsen, M. A., Resende, M., Alifrangis, M., Turner, L., Hviid, L., Theander, T. G. & Salanti, A., 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

Selective activation of TCR-G¿ cells in endemic Burkitt's lymphoma

Futagbi, G., Welbeck, J. E., Tetteh, J. K. A., Hviid, L. & Akanmori, B. D., 2007, In: Malaria Journal. 6, p. 69

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

VAR2CSA and protective immunity against pregnancy-associated Plasmodium falciparum malaria

Hviid, L. & Salanti, A., 2007, In: Parasitology. 134, Pt 13, p. 1871-6 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

Vß profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability

Loizon, S., Boeuf, P., Tetteh, J. K. A., Goka, B., Obeng-Adjei, G., Kurtzhals, J. A. L., Rogier, C., Akanmori, B. D., Mercereau-Puijalon, O., Hviid, L. & Behr, C., 2007, In: Microbes and Infection. 9, 11, p. 1252-9 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

2006

Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes

Barfod, L., Nielsen, M. A., Turner, L., Dahlbäck, M., Jensen, A. T. R., Hviid, L., Theander, T. G. & Salanti, A., 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

49 Citations (Scopus)

Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration

Dahlbäck, M., Rask, T. S., Andersen, P. H., Nielsen, M. A., Ndam, N. T., Resende, M., Turner, L., Deloron, P., Hviid, L., Lund, O., Pedersen, A. G., Theander, T. G. & Salanti, A., 2006, In: PLoS Pathogens. 2, 11, p. e124

Research output: Contribution to journal › Journal article › Research › peer-review

69 Citations (Scopus)

Late recrudescence of Plasmodium falciparum malaria in pregnancy

Hviid, L. & Staalsoe, T., 2006, In: International Journal of Infectious Diseases. 10, 5, p. 412

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Le paludisme chez la femme enceinte

Translated title of the contribution: Pregnancy-associated malariaHviid, L., 2006, In: Medecine Tropicale. 66, 2, p. 130-2 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes

Lusingu, J. P. A., Jensen, A. T. R., Vestergaard, L. S., Minja, D. T., Dalgaard, M. B., Gesase, S., Mmbando, B. P., Kitua, A. Y., Lemnge, M. M., Cavanagh, D., Hviid, L. & Theander, T. G., 2006, In: Infection and Immunity. 74, 5, p. 2867-75 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

Haase, R. N., Megnekou, R., Lundquist, M., Ofori, M. F., Hviid, L. & Staalsoe, T., 2006, In: Infection and Immunity. 74, 5, p. 3035-8 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

48 Citations (Scopus)

2005

Differential induction of immunoglobulin G to Plasmodium falciparum variant surface antigens during the transmission season in Daraweesh, Sudan

Nielsen, M. A., Grevstad, B., A-Elgadir, T. M. E., Kurtzhals, J., Giha, H., Staalsoe, T., Hviid, L. & Theander, T. G., 2005, In: Journal of Infectious Diseases. 192, 3, p. 520-7 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Effects of pregnancy and intensity of Plasmodium falciparum transmission on immunoglobulin G subclass responses to variant surface antigens

Megnekou, R., Staalsoe, T., Taylor, D. W., Leke, R. & Hviid, L., 2005, In: Infection and Immunity. 73, 7, p. 4112-8 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans

Lavstsen, T., Magistrado, P., Hermsen, C. C., Salanti, A., Jensen, A. T. R., Sauerwein, R., Hviid, L., Theander, T. G. & Staalsoe, T., 2005, In: Malaria Journal. 4, 1, p. 21

Research output: Contribution to journal › Journal article › Research › peer-review

80 Citations (Scopus)

Maternal vitamin A supplementation and immunity to malaria in pregnancy in Ghanaian primigravids

Cox, S. E., Staalsoe, T., Arthur, P., Bulmer, J. N., Tagbor, H., Hviid, L., Frost, C., Riley, E. M. & Kirkwood, B. R., 2005, In: Tropical Medicine & International Health. 10, 12, p. 1286-97 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Naturally acquired immunity to Plasmodium falciparum malaria in Africa

Hviid, L., 2005, In: Acta Tropica. 95, 3, p. 270-5 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

89 Citations (Scopus)

Rapid acquisition of isolate-specific antibodies to chondroitin sulfate A-adherent Plasmodium falciparum isolates in Ghanaian primigravidae

Cox, S. E., Staalsoe, T., Arthur, P., Bulmer, J. N., Hviid, L., Yeboah-Antwi, K., Kirkwood, B. R. & Riley, E. M., 2005, In: Infection and Immunity. 73, 5, p. 2841-7 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

2004

Analysis of IgG with specificity for variant surface antigens expressed by placental Plasmodium falciparum isolates

Khattab, A., Reinhardt, C., Staalsoe, T., Fievet, N., Kremsner, P. G., Deloron, P., Hviid, L. & Klinkert, M-Q., 2004, In: Malaria Journal. 3, p. 21

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria

Cavanagh, D. R., Dodoo, D., Hviid, L., Kurtzhals, J., Theander, T. G., Akanmori, B. D., Polley, S., Conway, D. J., Koram, K. & McBride, J. S., 2004, In: Infection and Immunity. 72, 11, p. 6492-502 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

81 Citations (Scopus)

Compounds useful in the diagnosis and treatment of pregnancy-associated malaria

Theander, T. G., Salanti, A., Hviid, L., Staalsø, T., Jensen, A. T. R., Lavstsen, T. & Dahlbäck, M., 2004, Patent No. WO2004067559 A1, Priority date 27 Jan 2003, Priority No. WO2004067559 A1

Research output: Patent

Evidence for the involvement of VAR2CSA in pregnancy-associated malaria

Salanti, A., Dahlbäck, M., Turner, L., Nielsen, M. A., Barfod, L., Magistrado, P., Jensen, A. T. R., Lavstsen, T., Ofori, M. F., Marsh, K., Hviid, L. & Theander, T. G., 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

406 Citations (Scopus)

Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens

Nielsen, M. A., Vestergaard, L. S., Lusingu, J., Kurtzhals, J., Giha, H. A., Grevstad, B., Goka, B. Q., Lemnge, M. M., Jensen, J. B., Akanmori, B. D., Theander, T. G., Staalsoe, T. & Hviid, L., 2004, In: Infection and Immunity. 72, 6, p. 3531-5 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

Intermittent preventive sulfadoxine-pyrimethamine treatment of primigravidae reduces levels of plasma immunoglobulin G, which protects against pregnancy-associated Plasmodium falciparum malaria

Staalsoe, T., Shulman, C. E., Dorman, E. K., Kawuondo, K., Marsh, K. & Hviid, L., 2004, In: Infection and Immunity. 72, 9, p. 5027-30 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Malaria immunity in infants: a special case of a general phenomenon?

Hviid, L. & Staalsoe, T., 2004, In: Trends in Parasitology. 20, 2, p. 66-72 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

48 Citations (Scopus)

Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes

Jensen, A. T. R., Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, T., Chiucchiuini, A., Salanti, A., Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, M. A., Hviid, L., Sutherland, C., Staalsoe, T. & Theander, T. G., 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

238 Citations (Scopus)

15 Downloads (Pure)

The immuno-epidemiology of pregnancy-associated Plasmodium falciparum malaria: a variant surface antigen-specific perspective

Hviid, L., 2004, In: Parasite Immunology. 26, 11-12, p. 477-86 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

44 Citations (Scopus)

Variant surface antigens, virulence genes and the pathogenesis of malaria

Deitsch, K. W. & Hviid, L., 2004, In: Trends in Parasitology. 20, 12, p. 562-6 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria

Staalsoe, T., Shulman, C. E., Bulmer, J. N., Kawuondo, K., Marsh, K. & Hviid, L., 2004, In: Lancet. 363, 9405, p. 283-9 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

218 Citations (Scopus)

2003

CCR3 expression induced by IL-2 and IL-4 functioning as a death receptor for B cells

Jinquan, T., Jacobi, H. H., Jing, C., Millner, A., Sten, E., Hviid, L., Anting, L., Ryder, L. P., Glue, C., Skov, P. S., Jarman, E., Lamberth, K., Malling, H-J. & Poulsen, L. K., 2003, In: Journal of Immunology. 171, 4, p. 1722-31 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection

Ofori, M. F., Staalsoe, T., Bam, V., Lundquist, M., David, K. P., Browne, E. N. L., Akanmori, B. D. & Hviid, L., 2003, In: Infection and Immunity. 71, 3, p. 1584-6 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children

Staalsoe, T., Nielsen, M. A., Vestergaard, L. S., Jensen, A. T. R., Theander, T. G. & Hviid, L., 2003, In: Parasite Immunology. 25, 8-9, p. 421-7 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria

Jensen, A. T. R., Zornig, H. D., Buhmann, C., Salanti, A., Koram, K. A., Riley, E. M., Theander, T. G., Hviid, L. & Staalsoe, T., 2003, In: Infection and Immunity. 71, 7, p. 4193-6 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Mannose-binding lectin is a disease modifier in clinical malaria and may function as opsonin for Plasmodium falciparum-infected erythrocytes

Garred, P., Nielsen, M. A., Kurtzhals, J., Malhotra, R., Madsen, H. O., Goka, B. Q., Akanmori, B. D., Sim, R. B. & Hviid, L., 2003, In: Infection and Immunity. 71, 9, p. 5245-53 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

57 Citations (Scopus)

Maternally transmitted antibodies to pregnancy-associated variant antigens on the surface of erythrocytes infected with Plasmodium falciparum: relation to child susceptibility to malaria

Cot, M., Le Hesran, J. Y., Staalsoe, T., Fievet, N., Hviid, L. & Deloron, P., 2003, In: American Journal of Epidemiology. 157, 3, p. 203-9 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria

Salanti, A., Staalsoe, T., Lavstsen, T., Jensen, A. T. R., Sowa, M. P. K., Arnot, D. E., Hviid, L. & Theander, T. G., 2003, In: Molecular Microbiology. 49, 1, p. 179-91 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

515 Citations (Scopus)

Specificity and cross-reactivity of Plasmodium falciparum variant surface antigen-specific antibody responses

Hviid, L., Staalsoe, T., Nielsen, M. A. & Theander, T. G., 2003, In: Infection and Immunity. 71, 4, p. 2296

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

2002

Acute P. falciparum malaria induces a loss of CD28^- T IFN-¿ producing cells

Kemp, K., Akanmori, B. D., Kurtzhals, J. A. L., Adabayeri, V., Goka, B. Q. & Hviid, L., 2002, In: Parasite Immunology. 24, 11-12, p. 545-8 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

A sub-family of common and highly conserved Plasmodium falciparum var genes

Salanti, A., Jensen, A. T. R., Zornig, H. D., Staalsoe, T., Joergensen, L., Nielsen, M. A., Khattab, A., Arnot, D. E., Klinkert, M. Q., Hviid, L. & Theander, T. G., 2002, In: Molecular and Biochemical Parasitology. 122, 1, p. 111-5 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

Cytokine production and apoptosis among T cells from patients under treatment for Plasmodium falciparum malaria

Kemp, K., Akanmori, B. D., Adabayeri, V., Goka, B. Q., Kurtzhals, J. A. L., Behr, C. & Hviid, L., 2002, In: Clinical and Experimental Immunology. 127, 1, p. 151-7 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

43 Citations (Scopus)

Elevated levels of nitric oxide and low levels of haptoglobin are associated with severe malarial anaemia in African children

Gyan, B., Kurtzhals, J., Akanmori, B. D., Ofori, M., Goka, B. Q., Hviid, L. & Behr, C., 2002, In: Acta Tropica. 83, 2, p. 133-40 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

Lars Hviid

Research output

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