19962020

Research activity per year

Personal profile

Short presentation

As head of the TARGETS team my focus is on a family of "sticky" proteins known as the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). P. falciparum is the most pathogenic malaria parasite and a major cause of morbidity and mortality among children in sub-Saharan Africa. The virulence of P. falciparum is linked to its expression of PfEMP1 on the surface of infected erythrocytes; these proteins enable the parasites to "stick" to capillaries of the host and are involved in pathogenesis as well of development of immunity to malaria. We have identified a subset of PfEMP1 proteins of importance in severe malaria and are currently investigating their involvement in the molecular mechanisms elicited in cerebral malaria.

Primary fields of research

Research projects include in vitro molecular and immunological characterization of malaria PfEMP1 proteins associated with severe malaria in young children. I always have bachelor and masters projects on hand; please contact (here) if you are interested in learning more about research done in my research group. 

For Mendeley stats and citations see here.

My Researcher Profile at Google Scholar is here.

My ResearcherID profile is here.

My ResearchGate profile is here.

Fields of interest

  • Immunology and pathogenesis of severe P. falciparum malaria with a particular focus on cerebral malaria in children
  • Enhancing malaria research capacity in Africa

Teaching

Teaching immunology to undergraduate and graduate students at the Faculty of Health and Medical Sciences. University Coordinator of the MSc course “Chronic Inflammation. From Basic Research to Therapy”.

Possible conflicts of interest

None

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Keywords

  • Faculty of Health and Medical Sciences
  • Immunology and the Immune Defence
  • Malaria Immunology
  • Malaria vaccine

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