Darryl S Pickering

2019

Design and Synthesis of 2,3-trans-Proline Analogs as Ligands for the Ionotropic Glutamate Receptors and the Excitatory Amino Acid Transporters

Poulie, C. B. M., Alcaide Lopez, A., Krell-Jørgensen, M. P., Larsen, Y., Astier, E., Bjørn-Yoshimoto, W. E., Yi, F., Syrenne, J. T., Storgaard, M., Nielsen, B., Frydenvang, K. A., Jensen, A. A., Hansen, K. B., Pickering, D. S. & Bunch, L., 19 Jun 2019, In: A C S Chemical Neuroscience. 10, 6, p. 2989-3007 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

N-(7-(1H-imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide - a new kainate receptor selective antagonist and analgesic: Synthesis, X-ray crystallography, structure-affinity relationships, in vitro and in vivo pharmacology

Møllerud, S., Hansen, R. B., Pallesen, J. S., Temperini, P., Pasini, D., Bornholdt, J., Nielsen, B., Mamedova, E., Chalupnik, P., Paternain, A. V., Lerma, J., Del Castillo, M. D., Andreasen, J. T., Frydenvang, K., Kastrup, J. S., Johansen, T. N. & Pickering, D. S., 2019, In: ACS Chemical Neuroscience. 10, p. 4685-4695 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships and in vitro Pharmacology

Pallesen, J. S., Møllerud, S., Frydenvang, K. A., Pickering, D. S., Bornholt, J., Nielsen, B., Pasini, D., Han, L., Marconi, L., Kastrup, J. S. J. & Johansen, T. N., 20 Mar 2019, In: A C S Chemical Neuroscience. 10, p. 1841-1853 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology

Warfvinge, K., Edvinsson, L., Pickering, D. S. & Sheykhzade, M., 1 Nov 2019, In: Pharmacology. 104, p. 332-341 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Use of the 4-Hydroxy-Triazole Moiety as a Bioisosteric Tool for the Development of Ionotropic Glutamate Receptor Ligands

Sainas, S., Temperini, P., Farnsworth, J. C., Yi, F., Møllerud, S., Jensen, A. A., Nielsen, B., Kastrup, J. S. J., Hansen, K. B., Boschi, D., Pickering, D. S., Clausen, R. P. & Lolli, M., 9 May 2019, In: Journal of Medicinal Chemistry. 62, p. 4467-4482 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

2018

(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements, Structural and Biological Investigation.

Brogi, S., Brindisi, M., Butini, S., Kshirsagar, G., Maramai, S., Chemi, G., Gemma, S., Campiani, G., Novellino, E., Fiorenzani, P., Pinassi, J., Aloisi, A. M., Gynther, M., Venskutonyte, R., Han, L., Frydenvang, K. A., Kastrup, J. S. J. & Pickering, D. S., 8 Mar 2018, In: Journal of Medicinal Chemistry. 61, 5, p. 2124-2130 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Vascular and molecular pharmacology of the metabolically stable CGRP analogue, SAX

Sheykhzade, M., Abdolalizadeh, B., Koole, C., Pickering, D. S., Dreisig, K., Johansson, S. E., Abboud, B. K., Dreier, R., Berg, J. O., Jeppesen, J. L., Sexton, P., Edvinsson, L., Wootten, D. & Sams, A., 15 Jun 2018, In: European Journal of Pharmacology. 829, p. 85-92

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

2017

Aryl- and heteroaryl-substituted phenylalanines as AMPA receptor ligands

Szymańska, E., Chałupnik, P., Johansen, T. N., Nielsen, B., Cuñado Moral, A. M., Pickering, D. S. & Kieć-Kononowicz, K., 1 Dec 2017, In: Chemical Biology & Drug Design. 90, p. 1271-1281 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N-Methyl-d-aspartate (NMDA) Receptor Antagonist

Gynther, M., Proietti Silvestri, I., Hansen, J. C., Hansen, K. B., Malm, T., Ishchenko, Y., Larsen, Y., Han, L., Kayser, S., Auriola, S., Petsalo, A., Nielsen, B., Pickering, D. S. & Bunch, L., 14 Dec 2017, In: Journal of Medicinal Chemistry. 60, 23, p. 9885-9904 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Binding and functional pharmacological characteristics of gepant-type antagonists in rat brain and mesenteric arteries

Sheykhzade, M., Amandi, N., Pla, M. V., Abdolalizadeh, B., Sams, A., Warfvinge, K., Edvinsson, L. & Pickering, D. S., 1 Mar 2017, In: Vascular Pharmacology. 90, p. 36-43 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Design and Synthesis of a Series of L-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid

Krogsgaard-Larsen, N., Delgar, C., Koch, K., Brown, P. M. G. E., Møller, C., Han, L., Huynh, T. H. V., Hansen, S. W., Nielsen, B., Bowie, D., Pickering, D. S., Kastrup, J. S. J., Frydenvang, K. A. & Bunch, L., 12 Jan 2017, In: Journal of Medicinal Chemistry. 60, 1, p. 441-457 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats: PSD-95 inhibition in experimental TBI

Sommer, J. B., Bach, A., Rytter, H. M., Gynther, M., Bjerre, A-S., Gram, M. G., Marschner, L., Strømgaard, K., Mogensen, J. & Pickering, D. S., 2017, In: Neurochemical Research. 42, 12, p. 3401-3413 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats

Sommer, J. B., Bach, A., Malá, H., Strømgaard, K., Mogensen, J. & Pickering, D. S., Oct 2017, In: Pharmacology, Biochemistry and Behavior. 161, p. 62-67 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Investigation of antidepressant-like and anxiolytic-like actions and cognitive and motor side effects of four N-methyl-D-aspartate receptor antagonists in mice

Refsgaard, L. K., Pickering, D. S. & Andreasen T., J., 1 Feb 2017, In: Behavioural Pharmacology. 28, 1, p. 37-47 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

In vitro and in vivo effects of a novel dimeric inhibitor of PSD‐95 on excitotoxicity and functional recovery after experimental traumatic brain injury

Sommer, J. B., Bach, A., Rytter, H. M., Strømgaard, K., Mogensen, J. & Pickering, D. S., 1 Jan 2017, In: European Journal of Neuroscience. 45, 2, p. 238-248 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Lessons from crystal structures of kainate receptors

Møllerud, S., Frydenvang, K. A., Pickering, D. S. & Kastrup, J. S. J., 1 Jan 2017, In: Neuropharmacology. 112, Part A, p. 16-28 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

Pharmacological characterization and binding modes of novel racemic and optically active phenylalanine-based antagonists of AMPA receptors

Szymańska, E., Nielsen, B., Johansen, T. N., Cuñado Moral, A. M., Pickering, D. S., Szczepańska, K., Mickowska, A. & Kieć-Kononowicz, K., 2017, In: European Journal of Medicinal Chemistry. 138, p. 874-883 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Pharmacology and crystal structure of novel 2,3-quinoxalinediones at kainate receptors

Møllerud, S., Pallesen, J. S., Pasini, D., Marconi, L., Han, L., Bornholt, J., Johansen, T. N., Kastrup, J. S., Pickering, D. S. & Frydenvang, K. A., Aug 2017, In: Journal of Neurochemistry. 142, S1, p. 124 1 p., MTU07-13.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Revisiting the Quinoxalinedione scaffold in the Construction of New Ligands for the Ionotropic Glutamate Receptors.

Demmer, C. S., Rombach, D., Liu, N., Nielsen, B., Pickering, D. S. & Bunch, L., 15 Nov 2017, In: A C S Chemical Neuroscience. 8, 11, p. 2477-2495 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Structure and affinity of two bicyclic glutamate analogues at AMPA and kainate receptors

Møllerud, S., Pinto, A., Marconi, L., Frydenvang, K. A., Thorsen, T. S., Laulumaa, S. K., Venskutonyte, R., Winther, N., Cunado Moral, A. M., Tamborini, L., Conti, P., Pickering, D. S. & Kastrup, J. S. J., 20 Sept 2017, In: A C S Chemical Neuroscience. 8, 9, p. 2056-2064 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

2016

A pharmacological profile of the high-affinity GluK5 kainate receptor

Møllerud, S., Kastrup, J. S. J. & Pickering, D. S., 2016, In: European Journal of Pharmacology. 788, p. 315-320 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Design, synthesis and structure-activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands

Szymańska, E., Chałupnik, P., Szczepańska, K., Moral, A. M. C., Pickering, D. S., Nielsen, B., Johansen, T. N. & Kieć-Kononowicz, K-K., 2016, In: Bioorganic & Medicinal Chemistry Letters. 26, 22, p. 5568-5572 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Effects of sertraline, duloxetine, vortioxetine, and idazoxan in the rat affective bias test

Refsgaard, L. K., Haubro, K., Pickering, D. S., Stuart, S., Robinson, E. & Andreasen T., J., 1 Oct 2016, In: Psychopharmacology. 233, 21, p. 3763-3770 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Effects of the dimeric PSD-95 inhibitor UCCB01-144 in mouse models of pain, cognition and motor function

Andreasen, J. T., Nasser, A., Caballero-Puntiverio, M., Sahlholt, M., Bach, A., Gynther, M., Strømgaard, K. & Pickering, D. S., 5 Jun 2016, In: European Journal of Pharmacology. 780, p. 166-73 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2

Krintel, C., Francotte, P., Pickering, D. S., Juknaite, L., Pøhlsgaaard, J., Olsen, L., Frydenvang, K. A., Goffin, E., Pirotte, B. & Kastrup, J. S. J., 7 Jun 2016, In: Biophysical Journal. 110, 11, p. 2397-2406 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber)

Jørgensen, K. B., Krogh-Jensen, K., Pickering, D. S., Kanui, T. & Abelson, K., 1 Jan 2016, In: Journal of Comparative Physiology A. Sensory, neural, and behavioral physiology. 202, 1, p. 7-15 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

79 Downloads (Pure)

Modelling Affective Pain in Mice: Effects of Inflammatory Hypersensitivity on Place Escape/Avoidance Behaviour, Anxiety and Hedonic State

Refsgaard, L. K., Hoffmann-Petersen, J., Sahlholt, M., Pickering, D. S. & Andreasen T., J., 15 Mar 2016, In: Journal of Neuroscience Methods. 262, p. 85-92 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Neto2 influences on kainate receptor pharmacology and function

Han, L., Howe, J. & Pickering, D. S., 1 Aug 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, p. 141-148 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Positive allosteric modulation of AMPA receptors differentially modulates the behavioural effects of citalopram in mouse models of antidepressant and anxiolytic action

Fitzpatrick, C. M., Larsen, M., Madsen, L., Pickering, D. S., Clausen, R. P. & Andreasen T., J., 26 Jun 2016, In: Behavioural Pharmacology. 27, 6, p. 549-555 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Structural rearrangement of the intracellular domains during AMPA receptor activation

Zachariassen, L. G., Katchan, L., Jensen, A. G., Pickering, D. S., Plested, A. & Kristensen, A. S., 5 Jul 2016, In: Proceedings of the National Academy of Sciences USA (PNAS). 113, 27, p. E3950-E3959 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate

Kristensen, O., Kristensen, L. B., Møllerud, S., Frydenvang, K. A., Pickering, D. S. & Kastrup, J. S. J., 6 Sept 2016, In: Structure. 24, 9, p. 1582-1589 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors

Szymanska, E., Frydenvang, K. A., Pickering, D. S., Krintel, C., Nielsen, B., Kooshki, A., Zachariassen, L. G., Olsen, L., Kastrup, J. S. J. & Johansen, T. N., 14 Jan 2016, In: Journal of Medicinal Chemistry. 59, 1, p. 448-461 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Synthesis and Pharmacological Characterization of the Selective GluK1 Radioligand (S)-2-Amino-3-(6-[3H]-2,4-dioxo-3,4-dihydrothieno[3,2-d]pyrimidin-1(2H)-yl)propanoic acid ([3H]-NF608)

Alcaide, A., Marconi, L., Marek, A., Haym, I., Nielsen, B., Møllerud, S., Jensen, M., Conti, P., Pickering, D. S. & Bunch, L., 2016, In: MedChemComm. 7, p. 2136-2144 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Systemic and Brain Pharmacokinetics of Perforin Inhibitor Prodrugs

Gynther, M., Pickering, D. S., Spicer, J., Denny, W. & Huttunen, K., 5 Jul 2016, In: Molecular Pharmaceutics. 13, 7, p. 2484-2491 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues

Wang, S-Y., Larsen, Y., Navarrete, C. V., Jensen, A. A., Nielsen, B., Al-Musaed, A., Frydenvang, K., Kastrup, J. S., Pickering, D. S. & Clausen, R. P., 10 Mar 2016, In: Journal of Medicinal Chemistry. 59, 5, p. 2244-2254 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

γ-Glutamyl-dipeptides: Easy tools to rapidly probe the stereoelectronic properties of ionotropic glutamate receptor binding pocket

Tamborini, L., Nicosia, V., Conti, P., Dall'Oglio, F., De Micheli, C., Nielsen, B., Jensen, A. A., Pickering, D. S. & Pinto, A., 1 Dec 2016, In: Tetrahedron. 72, 51, p. 8586-8492 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

2015

Binding Mode of an α-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1

Demmer, C. S., Møller, C., Brown, P. M. G. E., Han, L., Pickering, D. S., Nielsen, B., Bowie, D., Frydenvang, K., Kastrup, J. S. & Bunch, L., 17 Jun 2015, In: A C S Chemical Neuroscience. 6, p. 845-854 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Blood-brain barrier permeability and brain uptake mechanism of kainic Acid and dihydrokainic Acid

Gynther, M., Petsalo, A., Hansen, S. H., Bunch, L. & Pickering, D. S., 5 Mar 2015, In: Neurochemical Research. 40, 3, p. 542-549 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Differential role of AMPA receptors in mouse tests of antidepressant and anxiolytic action

Andreasen, J. T., Fitzpatrick, C. M., Larsen, M., Skovgaard, L., Nielsen, S. D., Clausen, R. P., Troelsen, K. & Pickering, D. S., 19 Mar 2015, In: Brain Research. 1601, p. 117-26 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Solid-Phase Peptide Synthesis of Human alfa-Calcitonin Gene-Related Peptide and Two Fluorescent Analogs.

Fuente-Moreno, M., Oddo, A., Sheykhzade, M., Pickering, D. S. & Hansen, P. R., 2015, Proceedings of the 24th American Peptide Symposium . 2 p.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid

Krogsgaard-Larsen, N., Storgaard, M., Møller, C., Demmer, C. S., Hansen, J., Han, L., Monrad, R. N., Nielsen, B., Tapken, D., Pickering, D. S., Kastrup, J. S., Frydenvang, K. & Bunch, L., 22 Jul 2015, In: Journal of Medicinal Chemistry. 58, 15, p. 6131-50 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

2014

Analogues of 3-Hydroxyisoxazole-Containing Glutamate Receptor Ligands Based on the 3-Hydroxypyrazole-Moiety: Design, Synthesis and Pharmacological Characterization

Jørgensen, L., Nielsen, B., Pickering, D. S., Kristensen, A. S., Frydenvang, K. A., Madsen, U. & Clausen, R. P., 24 Sept 2014, In: Neurochemical Research. 39, 10, p. 1895-1905 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Design, synthesis and in vitro pharmacology of GluK1 and GluK3 antagonists. Studies towards the design of subtype-selective antagonists through 2-carboxyethyl-phenylalanines with substituents interacting with non-conserved residues in the GluK binding sites

Sköld, N., Nielsen, B., Olsen, J., Han, L., Olsen, L., Madsen, U., Kristensen, J. L., Pickering, D. S. & Johansen, T. N., 1 Oct 2014, In: Bioorganic & Medicinal Chemistry. 22, 19, p. 5368-5377 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Forster Resonance Energy Transfer (FRET) Analysis of Dual CFP/YFP Labeled AMPA Receptors Reveals Structural Rearrangement within the C-Terminal Domain during Receptor Activation

Zachariassen, L. G., Katchan, M., Plested, A., Pickering, D. S. & Kristensen, A. S., 16 Feb 2014. 1 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain

Krintel, C., Frydenvang, K., Ceravalls de Rabassa, A., Kaern, A. M., Gajhede, M., Pickering, D. S. & Kastrup, J. S., May 2014, In: F E B S Journal. p. 2422–2430 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand-binding domain

Venskutonyte, R., Larsen, A. P., Frydenvang, K. A., Gajhede, M., Gefflaut, T., Pickering, D. S., Bunch, L. & Kastrup, J. S. J., 1 Oct 2014, In: ChemMedChem. 9, 10, p. 2254-2259 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2013

Chemo-enzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters

Assaf, Z., Larsen, A. P., Venskutonyte, R., Han, L., Abrahamsen, B., Nielsen, B., Gajhede, M., Kastrup, J. S., Jensen, A. A., Pickering, D. S., Frydenvang, K., Gefflaut, T. & Bunch, L., 28 Feb 2013, In: Journal of Medicinal Chemistry. 56, 4, p. 1614-1628

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site

Kvist, T., Steffensen, T. B., Greenwood, J. R., Mehrzad Tabrizi, F., Hansen, K. B., Gajhede, M., Pickering, D. S., Traynelis, S. F., Kastrup, J. S. & Bräuner-Osborne, H., 15 Nov 2013, In: The Journal of Biological Chemistry. 288, p. 33124-35 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Does increasing the ratio of AMPA-to-NMDA receptor mediated neurotransmission engender antidepressant action? Studies in the mouse forced swim and tail suspension tests

Andreasen T., J., Gynther, M. O. O., Rygaard, A., Bøgelund, T., Nielsen, S. D., Clausen, R. P., Mogensen, J. & Pickering, D. S., 24 Jun 2013, In: Neuroscience Letters. 546, p. 6-10 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain

Krintel, C., Harpsøe, K., Zachariassen, L. G., Peters, D., Frydenvang, K., Pickering, D. S., Gajhede, M. & Kastrup, J. S., Sept 2013, In: Acta crystallographica. Section D, Biological crystallography. 69, Pt 9, p. 1645-52 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Darryl S Pickering

Research output

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