Research output per year
Research output per year
Personal profile
Short presentation
- neuromedicinal chemistry
- epigenetic medicinal chemistry
- biostructure based SAR studies
- peptide and protein based ligands
- organic synthesis
Education/Academic qualification
Silicon in Organic Chemistry: New Tri- and Tetraalkoxysilanes, Aarhus University
Award Date: 28 Oct 1999
University of Southern Denmark
Award Date: 19 Sept 1994
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Dive into the research topics where Rasmus Prætorius Clausen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 12 Similar Profiles
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Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites
Maolanon, A. R., Risgaard, R., Wang, S. Y., Snoep, Y., Papangelis, A., Yi, F., Holley, D., Barslund, A. F., Svenstrup, N., Hansen, K. B. & Clausen, R. P., 16 Aug 2017, In: ACS Chemical Neuroscience. 8, 8, p. 1681-1687 7 p.Research output: Contribution to journal › Letter › peer-review
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Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues
Wang, S-Y., Larsen, Y., Navarrete, C. V., Jensen, A. A., Nielsen, B., Al-Musaed, A., Frydenvang, K., Kastrup, J. S., Pickering, D. S. & Clausen, R. P., 10 Mar 2016, In: Journal of Medicinal Chemistry. 59, 5, p. 2244-2254 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C
Leurs, U., Lohse, B., Rand, K. D., Ming, S., Riise, E. S., Cole, P. A., Kristensen, J. L. & Clausen, R. P., 19 Sept 2014, In: A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors
Lohse, B., Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, P. A. C., Olsen, L., Gajhede, M., Clausen, R. P. & Kristensen, J. L., 19 Sept 2011, In: Angewandte Chemie International Edition. 50, 39, p. 9100-9103Research output: Contribution to journal › Journal article › Research › peer-review
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α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)
Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner-Osborne, H., Frølund, B., Clausen, R. P., Olsen, J. V., Knudsen, G. M., Chebib, M. & Wellendorph, P., 14 Aug 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modulation of burst firing of neurons in nucleus reticularis of the thalamus by GluN2C-containing NMDA receptors
Liu, J., Shelkar, G. P., Zhao, F., Clausen, R. P. & Dravid, S. M., 2019, In: Molecular Pharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
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Use of the 4-Hydroxy-Triazole Moiety as a Bioisosteric Tool for the Development of Ionotropic Glutamate Receptor Ligands
Sainas, S., Temperini, P., Farnsworth, J. C., Yi, F., Møllerud, S., Jensen, A. A., Nielsen, B., Kastrup, J. S. J., Hansen, K. B., Boschi, D., Pickering, D. S., Clausen, R. P. & Lolli, M., 9 May 2019, In: Journal of Medicinal Chemistry. 62, p. 4467-4482 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elucidation of fluorine's impact on pKa and in vitro Pgp-mediated efflux for a series of PDE9 inhibitors
Fjelbye, K., Marigo, M., Clausen, R. P., Jørgensen, E. B., Christoffersen, C. T. & Juhl, K., 2018, In: MedChemComm. 9, 5, p. 893-896 4 p.Research output: Contribution to journal › Journal article › Research › peer-review