Christian William Wang

2019

Cerebral malaria is associated with differential cytoadherence to brain endothelial cells

Storm, J., Jespersen, J. S., Seydel, K. B., Szestak, T., Mbewe, M., Chisala, N. V., Phula, P., Wang, C. W., Taylor, T. E., Moxon, C. A., Lavstsen, T. & Craig, A. G., 1 Feb 2019, In: EMBO Molecular Medicine. 2019, 11, 15 p., e9164.

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

43 Downloads (Pure)

Meta-analysis of Plasmodium falciparum var signatures contributing to severe malaria in African children and Indian adults

Duffy, F., Bernabeu, M., Babar, P. H., Kessler, A., Wang, C. W., Vaz, M., Chery, L., Mandala, W. L., Rogerson, S. J., Taylor, T. E., Seydel, K. B., Lavstsen, T., Gomes, E., Kim, K., Lusingu, J., Rathod, P. K., Aitchison, J. D. & Smith, J. D., 1 Mar 2019, In: mBio. 10, 2, 16 p., e00217-19.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

15 Downloads (Pure)

2017

Binding of Plasmodium falciparum to CD36 can be shielded by the glycocalyx

Hempel, C., Wang, C. W., Kurtzhals, J. A. L. & Staalsø, T., 10 May 2017, In: Malaria Journal. 16, 11 p., 193.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

63 Downloads (Pure)

Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites

Mkumbaye, S. I., Minja, D. T. R., Jespersen, J. S., Alifrangis, M., Kavishe, R. A., Mwakalinga, S. B., Lusingu, J. P., Theander, T. G., Lavstsen, T. & Wang, C. W., 10 Feb 2017, In: Malaria Journal. 16, 1, 8 p., 69.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

115 Downloads (Pure)

Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

Saito, F., Hirayasu, K., Satoh, T., Wang, C. W., Lusingu, J., Arimori, T., Shida, K., Palacpac, N. M. Q., Itagaki, S., Iwanaga, S., Takashima, E., Tsuboi, T., Kohyama, M., Suenaga, T., Colonna, M., Takagi, J., Lavstsen, T., Horii, T. & Arase, H., 7 Dec 2017, In: Nature. 552, 7683, p. 101-105 5 p.

Research output: Contribution to journal › Letter › peer-review

46 Citations (Scopus)

48 Downloads (Pure)

Molecular evidence of malaria and zoonotic diseases among rapid diagnostic test-negative febrile patients in low-transmission season, Mali

Touré, M., Petersen, P. T., Bathily, S. N., Sanogo, D., Wang, C. W., Schiøler, K. L., Konradsen, F., Doumbia, S. & Alifrangis, M., 2017, In: American Journal of Tropical Medicine and Hygiene. 96, 2, p. 335-337

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Parasites causing cerebral falciparum malaria bind multiple endothelial receptors and express EPCR and ICAM-1-binding PfEMP1

Tuikue Ndam, N., Moussiliou, A., Lavstsen, T., Kamaliddin, C., Jensen, A. T. R., Mama, A., Tahar, R., Wang, C. W., Jespersen, J. S., Alao, J. M., Gamain, B., Theander, T. G. & Deloron, P., 15 Jun 2017, In: The Journal of Infectious Diseases. 215, 12, p. 1918-1925 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Plasmodium falciparum causing febrile infections express EPCR- binding PfEMP1

Mkumbaye, S., Wang, C. W., Jespersen, J. S., Petersen, J. E. V., Kavishe, R., Lusingu, J., Theander, T. G. & Lavstsen, T., Oct 2017, In: Tropical Medicine & International Health. 22, S1, p. 7-7 1S3.3.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria

Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L. & Higgins, M. K. & 1 others, Jensen, A. T. R., 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

64 Citations (Scopus)

441 Downloads (Pure)

The Severity of Plasmodium falciparum infection is associated with transcript levels of var genes encoding endothelial protein C receptor-binding P. falciparum erythrocyte membrane protein 1

Mkumbaye, S. I., Wang, C. W., Lyimo, E., Jespersen, J. S., Manjurano, A., Mosha, J., Kavishe, R. A., Mwakalinga, S. B., Minja, D. T. R., Lusingu, J. P., Theander, T. G. & Lavstsen, T., 1 Apr 2017, In: Infection and Immunity. 85, 4, 14 p., 4e00841-16.

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

2016

Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria

Pehrson, C., Mathiesen, L., Heno, K. K., Salanti, A., dos Santos Marques Resende, M., Dzikowski, R., Damm, P., Hansson, S. R., King, C. L., Schneider, H., Wang, C. W., Lavstsen, T., Theander, T. G., Knudsen, L. E. & Nielsen, M. A., 26 May 2016, In: Malaria Journal. 15, 12 p., 292.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

150 Downloads (Pure)

Cytoadhesion to gC1qR through Plasmodium falciparum erythrocyte membrane protein 1 in severe malaria

Magallón-Tejada, A., Machevo, S., Cisteró, P., Lavstsen, T., Aide, P., Rubio, M., Jiménez, A., Turner, L., Valmaseda, A., Gupta, H., De Las Salas, B., Mandomando, I., Wang, C. W., Petersen, J. E. V., Muñoz, J., Gascón, J., Macete, E., Alonso, P. L., Chitnis, C. E. & Bassat, Q. & 1 others, Mayor, A., 1 Nov 2016, In: PLOS Pathogens. 12, 11, 22 p., e1006011.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

92 Downloads (Pure)

Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1

Petersen, J. E. V., Mkumbaye, S. I., Vaaben, A. V., Manjurano, A., Lyimo, E., Kavishe, R. A., Mwakalinga, S. B., Mosha, J., Minja, D. T. R., Lusingu, J. P. A., Theander, T. G., Lavstsen, T. & Wang, C. W., 27 Oct 2016, In: Scientific Reports. 6, 9 p., 35950.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

92 Downloads (Pure)

Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains

Jespersen, J. S., Wang, C. W., Mkumbaye, S. I., Minja, D. T., Petersen, B., Turner, L., Petersen, J. E., Lusingu, J. P., Theander, T. G. & Lavstsen, T., 1 Aug 2016, In: EMBO Molecular Medicine. 8, 8, p. 839-850 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

53 Citations (Scopus)

118 Downloads (Pure)

2015

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

Hansson, H. H., Turner, L., Møller, L., Wang, C. W., Minja, D., Gesase, S., Mmbando, B., Bygbjerg, I. C., Theander, T. G., Lusingu, J. P. A., Alifrangis, M. & Lavstsen, T., 1 Dec 2015, In: Malaria Journal. 14, 9 p., 474.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

IgG antibodies to endothelial protein C receptor-binding Cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria

Turner, L., Lavstsen, T., Mmbando, B. P., Wang, C. W., Magistrado, P. A., Vestergaard, L. S., Ishengoma, D. S., Minja, D. T. R., Lusingu, J. P. & Theander, T. G., Aug 2015, In: Infection and Immunity. 83, 8, p. 3096-103 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant

Petersen, J. E. V., Bouwens, E. A. M., Tamayo, I., Turner, L., Wang, C. W., Stins, M., Theander, T. G., Hermida, J., Mosnier, L. O. & Lavstsen, T., Nov 2015, In: Thrombosis and Haemostasis. 114, 5, p. 1038-48 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

33 Citations (Scopus)

Rifins, rosetting, and red blood cells

Wang, C. W. & Hviid, L., 1 Jul 2015, In: Trends in Parasitology. 31, 7, p. 285-6 2 p.

Research output: Contribution to journal › Journal article › Commissioned › peer-review

9 Citations (Scopus)

Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria

Lau, C. K. Y., Turner, L., Jespersen, J. S., Lowe, E. D., Petersen, B., Wang, C. W., Petersen, J. E. V., Lusingu, J., Theander, T. G., Lavstsen, T. & Higgins, M. K., 14 Jan 2015, In: Cell Host & Microbe. 17, 1, p. 118-29 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

98 Citations (Scopus)

2014

Differences in gene transcriptomic pattern of Plasmodium falciparum in children with cerebral malaria and asymptomatic carriers

Almelli, T., Nuel, G., Bischoff, E., Aubouy, A., Elati, M., Wang, C. W., Dillies, M.-A., Coppée, J.-Y., Ayissi, G. N., Basco, L. K., Rogier, C., Ndam, N. T., Deloron, P. & Tahar, R., 5 Dec 2014, In: PloS one. 9, 12, p. e114401

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

2013

Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin

Bertin, G. I., Lavstsen, T., Guillonneau, F., Doritchamou, J., Wang, C. W., Jespersen, J. S., Ezimegnon, S., Fievet, N., Alao, M. J., Lalya, F., Massougbodji, A., Ndam, N. T., Theander, T. G. & Deloron, P., 29 Jul 2013, In: P L o S One. 8, 7, p. e68368

Research output: Contribution to journal › Journal article › Research › peer-review

44 Citations (Scopus)

Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1

Berger, S. S., Turner, L., Wang, C. W., Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, L., Nielsen, M. A., Theander, T. G. & Lavstsen, T., 9 Jul 2013, In: PloS one. 8, 7, p. e69117

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

Severe malaria is associated with parasite binding to endothelial protein C receptor

Turner, L., Lavstsen, T., Berger, S. S., Wang, C. W., Petersen, J. E. V., Avril, M., Brazier, A. J., Freeth, J., Jespersen, J. S., Nielsen, M. A., Magistrado, P., Lusingu, J., Smith, J. D., Higgins, M. K. & Theander, T. G., 27 Jun 2013, In: Nature. 498, 7455, p. 502-5 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

314 Citations (Scopus)

2012

A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

Claessens, A., Adams, Y., Ghumra, A., Lindergard, G., Buchan, C. C., Andisi, C., Bull, P. C., Mok, S., Gupta, A. P., Wang, C. W., Turner, L., Arman, M., Raza, A., Bozdech, Z. & Rowe, J. A., 26 Jun 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1772-81

Research output: Contribution to journal › Journal article › Research › peer-review

142 Citations (Scopus)

Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1

Wang, C. W., Lavstsen, T., Bengtsson, D. C., Magistrado, P. A., Berger, S. S., Marquard, A. M., Alifrangis, M., Lusingu, J. P., Theander, T. G. & Turner, L., 2012, In: Malaria Journal. 11, 1, p. 129

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes

Mwakalinga, S. B., Wang, C. W., Bengtsson, D. C., Turner, L., Dinko, B., Lusingu, J. P., Arnot, D. E., Sutherland, C. J., Theander, T. G. & Lavstsen, T., 2012, In: Malaria Journal. 11, 1, p. 429

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children

Lavstsen, T., Turner, L., Saguti, F., Magistrado, P. A., Rask, T. S., Jespersen, J. S., Wang, C. W., Berger, S. S., Baraka, V., Marquard, A. M., Seguin-Orlando, A., Willerslev, E., Gilbert, T., Lusingu, J. P. A. & Theander, T. G., 26 Jun 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1791-E1800 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

173 Citations (Scopus)

2011

Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers

Turner, L., Wang, C. W., Lavstsen, T., Mwakalinga, S. B., Sauerwein, R. W., Hermsen, C. C. & Theander, T. G., 2011, In: P L o S One. 6, 12, p. e29025

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

2010

Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum

Wang, C. W., Mwakalinga, S. B., Sutherland, C. J., Schwank, S., Sharp, S., Hermsen, C. C., Sauerwein, R. W., Theander, T. G. & Lavstsen, T., 2010, In: Malaria Journal. 9, 1, p. 147

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Macrogeographical variability in the great call of Hylobates agilis: assessing the applicability of vocal analysis in studies of fine-scale taxonomy of gibbons

Heller, R., Pedersen, A. F. S., Wang, C. W., Usman, F. & Dabelsteen, T., Feb 2010, In: American Journal of Primatology. 72, 2, p. 142-51 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

2009

Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines

Wang, C. W., Magistrado, P. A., Nielsen, M. A., Theander, T. G. & Lavstsen, T., 2009, In: International Journal for Parasitology. 39, 6, p. 655-64 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer

Wang, C. W., Hermsen, C. C., Sauerwein, R. W., Arnot, D. E., Theander, T. G. & Lavstsen, T., 2009, In: Parasitology International. 58, 4, p. 478-80 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

47 Citations (Scopus)

Christian William Wang

Research output

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