Birgitte Nielsen

2010

A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity

Stanley, N. J., Hutchinson, M. R., Kvist, T., Nielsen, B., Mathiesen, J. M., Bräuner-Osborne, H., Avery, T. D., Tiekink, E. R. T., Pedersen, D. S., Irvine, R. J., Abell, A. D. & Taylor, D. K., 15 Aug 2010, In: Bioorganic & Medicinal Chemistry. 18, 16, p. 6089-6098

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid

Frydenvang, K. A., Pickering, D. S., Greenwood, J. R., Krogsgaard-Larsen, N., Brehm, L., Nielsen, B., Vogensen, S. B., Hald, H., Kastrup, J. S., Krogsgaard-Larsen, P. & Clausen, R. P., 9 Dec 2010, In: Journal of Medicinal Chemistry. 53, 23, p. 8354-8361

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Novel 3-carboxy- and 3-phosphonopyrazoline amino acids as potent and selective NMDA receptor antagonists: Design, synthesis, and pharmacological characterization

Conti, P., Pinto, A., Tamborini, L., Madsen, U., Nielsen, B., Bräuner-Osborne, H., Hansen, K. B., Landucci, E., Pellegrini-Giampietro, D. E., De Sarro, G., Donato Di Paola, E. & De Micheli, C., 3 Sept 2010, In: ChemMedChem. 5, 9, p. 1465-1475

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Novel 4-(piperidin-4-yl)-1-hydroxypyrazoles as gamma-aminobutyric acid_A receptor ligands: synthesis, pharmacology, and structure-activity relationships

Møller, H. A., Sander, T., Kristensen, J. L., Nielsen, B., Krall, J., Bergmann, M. L., Christiansen, B., Balle, T., Jensen, A. A. & Frølund, B. F., 22 Apr 2010, In: Journal of Medicinal Chemistry. 53, 8, p. 3417-3421

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones

Christensen, M. K., Erichsen, K. D., Trojel-Hansen, C., Tjørnelund, J., Nielsen, S. J., Frydenvang, K. A., Johansen, T. N., Nielsen, B., Sehested, M., Jensen, P. B., Ikaunieks, M., Zaichenko, A., Loza, E., Kalvinsh, I. & Björkling, F., 14 Oct 2010, In: Journal of Medicinal Chemistry. 53, 19, p. 7140-7145 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

2009

3-Substituted phenylalanines as selective AMPA- and kainate receptor ligands

Szymanska, E., Pickering, D. S., Nielsen, B. & Johansen, T. N., 2009, In: Bioorganic & Medicinal Chemistry. 17, 17, p. 6390-401 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

4,4-Dimethyl- and diastereomeric 4-hydroxy-4-methyl-(2S)-glutamate analogues display distinct pharmacological profiles at ionotropic glutamate receptors and excitatory amino acid transporters

Bunch, L., Pickering, D. S., Gefflaut, T., Vinatier, V., Helaine, V., Amir, A., Nielsen, B. & Jensen, A. A., 2009, In: ChemMedChem. 4, 11, p. 1925-1929

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Pharmacological characterization of (4R)-alkyl glutamate analogues at the ionotropic glutamate receptors: focus on subtypes iGlu5-7

Bunch, L., Gefflaut, T., Alaux, S., Sagot, E., Nielsen, B. & Pickering, D. S., 2009, In: European Journal of Pharmacology. 609, p. 1-4

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Stereocontrolled synthesis and pharmacological evaluation of azetidine-2,3-dicarboxylic acids at NMDA receptors

Sivaprakasam, M., Hansen, K. B., David, O., Nielsen, B., Traynelis, S. F., Clausen, R. P., Couty, F. & Bunch, L., 2009, In: ChemMedChem. 4, 1, p. 110-117

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

Clausen, R. P., Naur, P., Kristensen, A. S., Greenwood, J. R., Strange, M., Bräuner-Osborne, H., Jensen, A. A., Nielsen, A. S. T., Geneser, U., Ringgaard, L. M., Nielsen, B., Pickering, D. S., Brehm, L., Gajhede, M., Krogsgaard-Larsen, P. & Kastrup, J. S., 2009, In: Journal of Medicinal Chemistry. 52, 15, p. 4911-4922

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

2008

Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2

Sagot, E., Jensen, A. A., Pickering, D. S., Pu, X., Umberti, M., Stensbøl, T. B., Nielsen, B., Assaf, Z., Aboab, B., Bolte, J., Gefflaut, T. & Bunch, L., 2008, In: Journal of Medicinal Chemistry. 51, 14, p. 4085-4092 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7.

Sagot, E., Pickering, D. S., Pu, X., Umberti, M., Stensbøl, T. B., Nielsen, B., Chapelet, M., Bolte, J., Gefflaut, T. & Bunch, L., 2008, In: Journal of Medicinal Chemistry. 51, 14, p. 4093-103

Research output: Contribution to journal › Journal article › Research › peer-review

44 Citations (Scopus)

N-Hydroxypyrazolyl glycine derivatives as selective N-methyl-D-aspartic acid receptor ligands

Clausen, R. P., Christensen, C., Hansen, K. B., Greenwood, J. R., Jørgensen, L., Micale, N., Madsen, J. C., Nielsen, B., Egebjerg, J., Bräuner-Osborne, H., Traynelis, S. F. & Kristensen, J. L., 2008, In: Journal of Medicinal Chemistry. 51, 14, p. 4179-87

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Novel high-affinity and selective biaromatic 4-substituted ¿-hydroxybutyric acid (GHB) analogues as GHB ligands: design, synthesis, and binding studies

Høg, S., Wellendorph, P., Nielsen, B., Frydenvang, K., Dahl, I. F., Bräuner-Osborne, H., Brehm, L., Frølund, B. & Clausen, R. P., 2008, In: Journal of Medicinal Chemistry. 51, 24, p. 8088-8095

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid

Pinto, A., Conti, P., De Amici, M., Tamborini, L., Madsen, U., Nielsen, B., Christesen, T., Bräuner-Osborne, H. & De Micheli, C., 2008, In: Journal of Medicinal Chemistry. 51, 7, p. 2311-2315

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

2007

5-substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel ¿-aminobutyric acid_C receptor agonists

Madsen, C., Jensen, A. A., Liljefors, T., Kristiansen, U., Nielsen, B., Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, P. & Frølund, B. F., 2007, In: Journal of Medicinal Chemistry. 50, 17, p. 4147-4161

Research output: Contribution to journal › Journal article › Research › peer-review

42 Citations (Scopus)

5-Substituted imidazole-4-acetic acid analogues: Synthesis, modeling, and pharmacological characterization of a series of novel γ-aminobutyric acidC receptor agonists

Madsen, C., Jensen, A. A., Liljefors, T., Kristiansen, U., Nielsen, B., Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, P. & Frølund, B., 2007, In: Journal of Medicinal Chemistry. 50, p. 4147-4161

Research output: Contribution to journal › Journal article › Research › peer-review

42 Citations (Scopus)

A tetrazolyl-substituted subtype-selective AMPA receptor agonist

Vogensen, S. B., Frydenvang, K. A., Greenwood, J. R., Postorino, G., Nielsen, B., Pickering, D. S., Ebert, B., Bølcho, U., Egebjerg, J., Gajhede, M., Kastrup, J. S. J., Johansen, T. N., Clausen, R. P. & Krogsgaard-Larsen, P., 2007, In: Journal of Medicinal Chemistry. 50, 10, p. 2408-2414

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

Novel 5-substituted 1-pyrazolol analogues of ibotenic acid: synthesis and pharmacology at glutamate receptors

Jørgensen, C. G., Bräuner-Osborne, H., Nielsen, B., Kehler, J., Clausen, R. P., Krogsgaard-Larsen, P. & Madsen, U., 2007, In: Bioorganic & Medicinal Chemistry. 15, 10, p. 3524-3538

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Synthesis and pharmacological characterization at glutamate receptors of erythro- and threo-tricholomic acid and homologues thereof

Conti, P., De Amici, M., Roda, G., Pinto, A., Tamborini, L., Madsen, U., Nielsen, B., Bräuner-Osborne, H. & De Micheli, C., 2007, In: Tetrahedron. 63, 10, p. 2249-2256

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid

Conti, P., Caligiuri, A., Pinto, A., Roda, G., Tamborini, L., Nielsen, B., Madsen, U., Frydenvang, K. A., Colombo, A. & De Micheli, C., 2007, In: European Journal of Medicinal Chemistry. 42, 8, p. 1059-1068

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ibotenic acid

Jørgensen, C. G., Clausen, R. P., Hansen, K. B., Bräuner-Osborne, H., Nielsen, B., Metzler, B., Kehler, J., Krogsgaard-Larsen, P. & Madsen, U., 2007, In: Organic & Biomolecular Chemistry. 5, 3, p. 463-471

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

2006

Aminolysis of resin-bound N-nosylaziridine-2-carboxylic acids

Olsen, C. A., Christensen, C., Nielsen, B., Farah, M. M., Mohamed, F. M., Witt, M., Clausen, R. P., Kristensen, J. L., Franzyk, H. & Jaroszewski, J. W., 2006, In: Organic Letters. 8, 15, p. 3371-4 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Hydroxy-1,2,5-oxadiazolyl moiety as bioisoster of the carboxy function.Synthesis, ionization constants and pharmacological characterization of gamma-aminobutyric acid (GABA) related compounds

Lolli, M. L., Hansen, S. L., Rolando, B., Nielsen, B., Wellendorph, P., Madsen, K., Larsen, O. M., Kristiansen, U., Fruttero, R., Gasco, A. & Johansen, T. N., 2006, In: J. Med. Chem.. 49, p. 4442-4446 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

MEDI 480-Novel lipophilic gamma-hydroxybutyrate (GHB) analogs with high affinity to GHB sites in rat brain

Hog, S., Wellendorph, P., Nielsen, B., Frolund, B. & Clausen, R. P., 10 Sept 2006, In: American Chemical Society. Abstracts of Papers (at the National Meeting). 232

Research output: Contribution to journal › Conference abstract in journal › Research

Potent 4-Arylalkyl-Substituted 3-Isothiazolol GABAA Competitive/Noncompetitive Antagonists: Synthesis and Pharmacology

Krehan, D., i Storustovu, S., Liljefors, T., Ebert, B., Nielsen, B., Krogsgaard-Larsen, P. & Frølund, B., 2006, In: Journal of Medicinal Chemistry. 49, p. 1388–1396

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Rational design and enantioselective synthesis of (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid - a novel inhibitor at human glutamate transporter subtypes 1, 2, and 3

Bunch, L., Nielsen, B., Jensen, A. A. & Bräuner-Osborne, H., 2006, In: Journal of Medicinal Chemistry. 49, 1, p. 172-8 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Synthesis of 3-Hydroxy- and 3-Carboxy-Δ2-isoxazoline Amino Acids and Evaluation of Their Interaction with GABA Receptors and Transporters

Conti, P., De Amici, M., Pinto, A., Tamborini, L., Grazioso, G., Frølund, B., Nielsen, B., Thomsen, C., Ebert, B. & De Michelli, C., 2006, In: European Journal of Pharmacology. p. 5533–5542

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

2005

4-Alkylated homoibotenic acid (HIBO) analogues: versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes

Madsen, U., Pickering, D. S., Nielsen, B. & Bräuner-Osborne, H., 2005, In: Neuropharmacology. 49 Suppl 1, p. 114-9 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Azetidinic amino acids: stereocontrolled synthesis and pharmacological characterization as ligands for glutamate receptors and transporters

Bräuner-Osborne, H., Bunch, L., Chopin, N., Couty, F., Evano, G., Jensen, A. A., Kusk, M. L., Nielsen, B. & Rabasso, N., 2005, In: Organic & Biomolecular Chemistry. 3, 21, p. 3926-36 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

49 Citations (Scopus)

Convergent synthesis and pharmacology of substituted tetrazolyl-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid analogues

Vogensen, SB., Clausen, R. P., Greenwood, JR., Johansen, T. N., Pickering, DS., Nielsen, B., Ebert, B. & Krogsgaard-Larsen, P., 5 May 2005, In: Journal of Medicinal Chemistry. 48, 9, p. 3438-3442

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Novel cyclic gamma-hydroxybutyrate (GHB) analogs with high affinity and stereoselectivity of binding to GHB sites in rat brain

Wellendorph, P., Høg, S., Greenwood, J. R., de Lichtenberg, A., Nielsen, B., Frølund, B., Brehm, L., Clausen, R. P. & Bräuner-Osborne, H., Oct 2005, In: Journal of Pharmacology and Experimental Therapeutics. 315, 1, p. 346-51

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

Potent 4-Aryl- or 4-Arylalkyl-Substituted 3-Isoxazolol GABA_A Antagonists: Synthesis, Pharmacology, and Molecular Modeling

Frølund, B., Jensen, L. S., Guandalini, L., Canillo, C., Vestergaard, H. T., Kristiansen, U., Nielsen, B., Stensbøl, T. B., Madsen, C., Krogsgaard-Larsen, P. & Liljefors, T., 2005, In: Journal of Medicinal Chemistry. 48, p. 427–439

Research output: Contribution to journal › Journal article › Research › peer-review

Synthesis, binding affinity at glutamic acid receptors, neuroprotective effects, and molecular modeling investigation of novel dihydroisoxazole amino acids

Conti, P., De Amici, M., Grazioso, G., Roda, G., Pinto, A., Hansen, K. B., Nielsen, B., Madsen, U., Bräuner-Osborne, H., Egebjerg, J., Vestri, V., Pellegrini-Giampietro, D. E., Sibille, P., Acher, F. C. & De Micheli, C., 6 Oct 2005, In: Journal of Medicinal Chemistry. 48, 20, p. 6315-25

Research output: Contribution to journal › Journal article › Research › peer-review

43 Citations (Scopus)

Synthesis of novel N1-substituted bicyclic pyrazole amino acids and evaluation of their interaction with glutamate receptors

Conti, P., Grazioso, G., di Ventimiglia, S. J., Pinto, A., Roda, G., Madsen, U., Bräuner-Osborne, H., Nielsen, B., Costagli, C. & Galli, A., Jun 2005, In: Chemistry & Biodiversity. 2, 6, p. 748-57

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: synthesis, modelling and molecular pharmacology

Frølund, B., Greenwood, J. R., Holm, M. M., Egebjerg, J., Madsen, U., Nielsen, B., Bräuner-Osborne, H., Stensbøl, T. B. & Krogsgaard-Larsen, P., 15 Sept 2005, In: Bioorganic & Medicinal Chemistry. 13, 18, p. 5391-8

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

2004

A stereochemical anomaly: the cyclised (R)-AMPA analogue (R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid [(R)-5-HPCA] resembles (S)-AMPA at glutamate receptors

Vogensen, SB., Greenwood, JR., Varming, A. R., Brehm, L., Pickering, DS., Nielsen, B., Liljefors, T., Clausen, R. P., Johansen, T. N. & Krogsgaard-Larsen, P., 2004, In: Organic & Biomolecular Chemistry. 2, 2, p. 206-213

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

Design, synthesis, and pharmacological characterization of novel, potent NMDA receptor antagonists

Conti, P., De Amici, M., Grazioso, G., Roda, G., Barberis Negra, F. F., Nielsen, B., Stensbøl, T. B., Madsen, U., Bräuner-Osborne, H., Frydenvang, K. A., De Sarro, G., Toma, L. & De Micheli, C., 30 Dec 2004, In: Journal of Medicinal Chemistry. 47, 27, p. 6740-8 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Ibotenic acid and thioibotenic acid: a remarkable difference in activity at group III metabotropic glutamate receptors

Hermit, M. B., Greenwood, J. R., Nielsen, B., Bunch, L., Jørgensen, C. G., Vestergaard, H. T., Stensbøl, T. B., Sanchez, C., Krogsgaard-Larsen, P., Madsen, U. & Bräuner-Osborne, H., 23 Feb 2004, In: European Journal of Pharmacology. 486, 3, p. 241-50

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA

Brehm, L., Greenwood, J. R., Sløk, F. A., Holm, M. M., Nielsen, B., Geneser, U., Stensbøl, T. B., Bräuner-Osborne, H., Begtrup, M., Egebjerg, J. & Krogsgaard-Larsen, P., Aug 2004, In: Chirality. 16, 7, p. 452-66

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid

Clausen, R. P., Hansen, K. B., Calí, P., Nielsen, B., Greenwood, J. R., Begtrup, M., Egebjerg, J. & Bräuner-Osborne, H., 19 Sept 2004, In: European Journal of Pharmacology. 499, 1-2, p. 35-44 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

2003

(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology

Brehm, L., Greenwood, J. R., Hansen, K. B., Nielsen, B., Egebjerg, J., Stensbøl, T. B., Bräuner-Osborne, H., Sløk, F. A., Kronborg, T. T. A. & Krogsgaard-Larsen, P., 10 Apr 2003, In: Journal of Medicinal Chemistry. 46, 8, p. 1350-8

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Aza-THIP and Related Analogues of THIP as GABA_C Antagonists

Krehan, D., Frølund, B., Ebert, B., Nielsen, B., Krogsgaard-Larsen, P., Johnston, G. A. R. & Chebib, M., 2003, In: Bioorganic and Medicinal Chemistry. 11, p. 4891–4896

Research output: Contribution to journal › Journal article › Research › peer-review

Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO)

Bjerrum, E. J., Kristensen, A. S., Pickering, D. S., Greenwood, J. R., Nielsen, B., Liljefors, T., Schousboe, A., Bräuner-Osborne, H., Madsen, U. & Pickering, D., 2003, In: Journal of Medicinal Chemistry. 46, 11, p. 2246-9 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

39 Citations (Scopus)

Synthesis and in vitro pharmacology at AMPA and kainate preferring glutamate receptors of 4-heteroarylmethylidene glutamate analogues

Valgeirsson, J., Christensen, J. K., Kristensen, A. S., Pickering, D. S., Nielsen, B., Fischer, C., Bräuner-Osborne, H., Nielsen, E. Ø., Krogsgaard-Larsen, P. & Madsen, U., 2003, In: Bioorganic & Medicinal Chemistry. 11, 20, p. 4341-9 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

2002

2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors

Johansen, T. N., Janin, Y. L., Nielsen, B., Frydenvang, K. A., Bräuner-Osborne, H., Stensbøl, T. B., Vogensen, S. B., Madsen, U. & Krogsgaard-Larsen, P., 2002, In: Bioorganic & Medicinal Chemistry. 10, 7, p. 2259-66 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Glutamate receptor ligands: synthesis, stereochemistry, and enantiopharmacology of methylated 2-aminoadipic acid analogs

Guldbrandt, M., Johansen, T. N., Frydenvang, K. A., Bräuner-Osborne, H., Stensbøl, T. B., Nielsen, B., Karla, R., Santi, F., Krogsgaard-Larsen, P. & Madsen, U., 2002, In: Chirality. 14, 4, p. 351-63 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Selective agonists at group II metabotropic glutamate receptors: synthesis, stereochemistry, and molecular pharmacology of (S)- and (R)-2-amino-4-(4-hydroxy[1,2,5]thiadiazol-3-yl)butyric acid

Clausen, R. P., Bräuner-Osborne, H., Greenwood, J. R., Hermit, M. B., Stensbøl, T. B., Nielsen, B. & Krogsgaard-Larsen, P., 12 Sept 2002, In: Journal of Medicinal Chemistry. 45, 19, p. 4240-5

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

2001

Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA

Johansen, T. N., Stensbøl, T. B., Nielsen, B., Vogensen, S. B., Frydenvang, K. A., Sløk, F. A., Bräüner-Osborne, H., Madsen, U. & Krogsgaard-Larsen, P., 2001, In: Chirality. 13, 9, p. 523-32 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist

Stensbøl, T. B., Jensen, H. S., Nielsen, B., Johansen, T. N., Egebjerg, J., Frydenvang, K. A. & Krogsgaard-Larsen, P., 2001, In: European Journal of Pharmacology. 411, 3, p. 245-53 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Birgitte Nielsen

Research output

Search results