Hydroxy-1,2,5-oxadiazolyl moiety as bioisoster of the carboxy function.Synthesis, ionization constants and pharmacological characterization of gamma-aminobutyric acid (GABA) related compounds

Marco L. Lolli; Suzanne L.  Hansen; Barbara  Rolando; Birgitte Nielsen; Petrine Wellendorph; Karsten  Madsen; Orla Miller  Larsen; Uffe Kristiansen; Roberta  Fruttero; Alberto  Gasco; Tommy Nørskov Johansen

doi:10.1021/jm051288b

Hydroxy-1,2,5-oxadiazolyl moiety as bioisoster of the carboxy function.Synthesis, ionization constants and pharmacological characterization of gamma-aminobutyric acid (GABA) related compounds

Marco L. Lolli, Suzanne L. Hansen, Barbara Rolando, Birgitte Nielsen, Petrine Wellendorph, Karsten Madsen, Orla Miller Larsen, Uffe Kristiansen, Roberta Fruttero, Alberto Gasco, Tommy Nørskov Johansen

27 Citations (Scopus)

Original language	English
Journal	J. Med. Chem.
Volume	49
Pages (from-to)	4442-4446
Number of pages	5
DOIs	https://doi.org/10.1021/jm051288b
Publication status	Published - 2006

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10.1021/jm051288b

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Lolli, M. L., Hansen, S. L., Rolando, B., Nielsen, B., Wellendorph, P., Madsen, K., Larsen, O. M., Kristiansen, U., Fruttero, R., Gasco, A., & Johansen, T. N. (2006). Hydroxy-1,2,5-oxadiazolyl moiety as bioisoster of the carboxy function.Synthesis, ionization constants and pharmacological characterization of gamma-aminobutyric acid (GABA) related compounds. J. Med. Chem., 49, 4442-4446. https://doi.org/10.1021/jm051288b

Hydroxy-1,2,5-oxadiazolyl moiety as bioisoster of the carboxy function.Synthesis, ionization constants and pharmacological characterization of gamma-aminobutyric acid (GABA) related compounds. / Lolli, Marco L.; Hansen, Suzanne L. ; Rolando, Barbara et al.

In: J. Med. Chem., Vol. 49, 2006, p. 4442-4446.

Research output: Contribution to journal › Journal article › Research › peer-review

Lolli, ML, Hansen, SL, Rolando, B, Nielsen, B , Wellendorph, P, Madsen, K, Larsen, OM, Kristiansen, U, Fruttero, R, Gasco, A & Johansen, TN 2006, 'Hydroxy-1,2,5-oxadiazolyl moiety as bioisoster of the carboxy function.Synthesis, ionization constants and pharmacological characterization of gamma-aminobutyric acid (GABA) related compounds', J. Med. Chem., vol. 49, pp. 4442-4446. https://doi.org/10.1021/jm051288b

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title = "Hydroxy-1,2,5-oxadiazolyl moiety as bioisoster of the carboxy function.Synthesis, ionization constants and pharmacological characterization of gamma-aminobutyric acid (GABA) related compounds",

author = "Lolli, {Marco L.} and Hansen, {Suzanne L.} and Barbara Rolando and Birgitte Nielsen and Petrine Wellendorph and Karsten Madsen and Larsen, {Orla Miller} and Uffe Kristiansen and Roberta Fruttero and Alberto Gasco and Johansen, {Tommy N{\o}rskov}",

year = "2006",

doi = "10.1021/jm051288b",

language = "English",

volume = "49",

pages = "4442--4446",

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T1 - Hydroxy-1,2,5-oxadiazolyl moiety as bioisoster of the carboxy function.Synthesis, ionization constants and pharmacological characterization of gamma-aminobutyric acid (GABA) related compounds

AU - Lolli, Marco L.

AU - Hansen, Suzanne L.

AU - Rolando, Barbara

AU - Nielsen, Birgitte

AU - Wellendorph, Petrine

AU - Madsen, Karsten

AU - Larsen, Orla Miller

AU - Kristiansen, Uffe

AU - Fruttero, Roberta

AU - Gasco, Alberto

AU - Johansen, Tommy Nørskov

PY - 2006

Y1 - 2006

U2 - 10.1021/jm051288b

DO - 10.1021/jm051288b

M3 - Journal article

VL - 49

SP - 4442

EP - 4446

JO - J. Med. Chem.

JF - J. Med. Chem.

ER -