Department of Experimental Medicine

2017

Fighting for the family: overcoming distances in time and space

Heiselberg, M. H., 2017, In: Critical Military Studies. 3, 1, p. 69-86 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Four simple rules that are sufficient to generate the mammalian blastocyst

Nissen, S. B., Perera Pérez, M., Martin Gonzalez, J., Morgani, S. M. C., Jensen, M. H., Sneppen, K., Brickman, J. M. & Trusina, A., 12 Jul 2017, In: PLOS Biology. 15, 7, p. 1-30 e2000737.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

115 Downloads (Pure)

Håndtering, hold og brug af forsøgsdyr

Abelson, K., Krohn, T. C. & Østergaard, G., 2017, Forsøgsdyrkundskab: En håndbog om forsøgsdyr og dyreforsøg. Bratbo Sørensen, D. (ed.). Denmark: Københavns Universitet, p. 37-68

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review

Hyperpolarized ¹³C-MRSI and PET (hyperPET) in an Osteomyelitis Pig Model: A Pilot Study

Rahbek, S., Gutte, H., Johannesen, H. H., Koch, J., Jensen, L. K., Dich-Jørgensen, K., Jensen, H. E., Hansen, A. E. & Kjær, A., Mar 2017, In: IEEE Transactions on Radiation and Plasma Medical Sciences. 1, 2, 4 p., 164-167.

Research output: Contribution to journal › Journal article › Research › peer-review

Introduction to the Handbook of Primate Behavioral Management

Schapiro, S., 1 Jan 2017, Handbook of Primate Behavioral Management. Steven J., S. (ed.). 1 ed. Boca Raton: CRC Press, p. 3-8

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

Is there a reasonable excuse for not providing post-operative analgesia when using animal models of peripheral neuropathic pain for research purposes?

Hestehave, S., Munro, G., Christensen, R., Brønnum Pedersen, T., Arvastson, L., Hougaard, P. & Abelson, K. S. P., 22 Nov 2017, In: PloS one. 12, 11, p. 1-23 e0188113.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

60 Downloads (Pure)

Lipocalin-2 from both myeloid cells and the epithelium combats Klebsiella pneumoniae lung infection in mice

Cramer, E. P., Dahl, S. L., Rozell, B., Knudsen, K. J., Thomsen, K., Moser, C., Cowland, J. B. & Borregaard, N., 18 May 2017, In: Blood. 129, 20, p. 2813-2817 5 p.

Research output: Contribution to journal › Comment/debate › Research

10 Citations (Scopus)

Managing a Behavioral Management Program

Schapiro, S. & Lambeth, S. P., 1 Jan 2017, Handbook of Primate Behavioral Management. Steven J., S. (ed.). 1 ed. Boca Raton: CRC Press, p. 265-278

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

1 Citation (Scopus)

Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development

Sankar, A., Kooistra, S. M., Gonzalez, J. M., Ohlsson, C., Poutanen, M. & Helin, K., 1 Jan 2017, In: Development (Cambridge). 144, 18, p. 3264-3277 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Modulation of formalin-induced pain-related behaviour by clonidine and yohimbine in the Speke's hinged tortoise (Kiniskys spekii)

Makau, C. M., Towett, P. K., Abelson, K. S. P. & Kanui, T. I., Oct 2017, In: Journal of Veterinary Pharmacology and Therapeutics. 40, 5, p. 439–446

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response

Jensen, L. K., Koch, J., Dich-Jørgensen, K., Aalbaek, B., Petersen, A., Fuursted, K., Bjarnsholt, T., Kragh, K. N., Tøtterup, M., Bue, M., Hanberg, P., Søballe, K., Heegaard, P. M. H. & Jensen, H. E., Oct 2017, In: Journal of Orthopaedic Research. 35, 10, p. 2211–2221

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

45 Downloads (Pure)

Rules, Regulations, Guidelines, and Directives

Hau, J. & Bayne, K., 1 Jan 2017, Handbook of Primate Behavioral Management. Steven J., S. (ed.). 1 ed. Boca Raton: CRC Press, p. 25-36

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

2 Citations (Scopus)

Socially transmitted diffusion of a novel behavior from subordinate chimpanzees

Watson, S. K., Reamer, L. A., Mareno, M. C., Vale, G., Harrison, R. A., Lambeth, S. P., Schapiro, S. & Whiten, A., Jun 2017, In: American Journal of Primatology. 79, 6, 10 p., e22642.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Triarchic Psychopathy Dimensions in Chimpanzees (Pan troglodytes): Investigating Associations with Genetic Variation in the Vasopressin Receptor 1A Gene

Latzman, R. D., Schapiro, S. J. & Hopkins, W. D., 17 Jul 2017, In: Frontiers in Neuroscience. 11, JUL, 10 p., 407.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

41 Downloads (Pure)

Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats: Does it matter?

Kristensen, P. J., Heegaard, A. M., Kristensen, S. H., Jeggo, R. D., Bjerrum, O. J. & Munro, G., 1 Apr 2017, In: European Journal of Pain. 21, 4, p. 692-704 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

2016

Albumin Is an Overlooked but Highly Relevant Allergen Potentially Affecting Laboratory Animal Professionals

Kalliokoski, O., Kousted, T. M., Koch, J. & Hau, J., 2016, In: American Association for Laboratory Animal Science. Journal. 55, 5, p. 696 1 p., PS70.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Angiogenesis PET Tracer Uptake (⁶⁸Ga-NODAGA-E[(cRGDyK)]₂) in Induced Myocardial Infarction in Minipigs

Rasmussen, T., Follin, B., Kastrup, J., Brandt-Larsen, M., Madsen, J., Emil Christensen, T., Pharao Hammelev, K., Hasbak, P. & Kjær, A., 1 Jun 2016, In: Diagnostics. 6, 2, 4 p., 26.

Research output: Contribution to journal › Journal article › Research › peer-review

78 Downloads (Pure)

Applicability of Commercially Available ELISA Kits for the Quantification of Faecal Immunoreactive Corticosterone Metabolites in Mice

Abelson, K. S. P., Kalliokoski, O., Teilmann, A. C. & Hau, J., 1 Nov 2016, In: In Vivo. 30, 6, p. 739-744 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

201 Downloads (Pure)

Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings

Madsen, M. F., Kanters, J. K., Pedersen, P. J., Haugaard, M. M., Carstensen, H., Olsen, L. H. & Buhl, R., 28 Nov 2016, In: BMC Veterinary Research. 12, 10 p., 266.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

121 Downloads (Pure)

Carotid Catheterization and Automated Blood Sampling Induce Systemic IL-6 Secretion and Local Tissue Damage and Inflammation in the Heart, Kidneys, Liver and Salivary Glands in NMRI Mice

Teilmann, A. C., Rozell, B., Kalliokoski, O., Hau, J. & Abelson, K. S. P., 10 Nov 2016, In: P L o S One. 11, 11, p. 1-14 14 p., e0166353.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

152 Downloads (Pure)

Comparison of Per Diem Rates in Europe and the USA

Hau, J. & Kalliokoski, O., Sept 2016, In: American Association for Laboratory Animal Science. Journal. 55, 5, p. 679-680 2 p., PS1.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Effects of Implant-Associated Osteomyelitis on Cefuroxime Bone Pharmacokinetics: Assessment in a Porcine Model

Tøttrup, M., Bue, M., Koch, J., Jensen, L. K., Hanberg, P., Aalbaek, B., Fuursted, K., Jensen, H. E. & Søballe, K., 2 Mar 2016, In: Journal of Bone and Joint Surgery: American Volume. 98, 5, p. 363-369 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency

Martin Gonzalez, J., Morgani, S. M., Bone, R. A., Bonderup, K., Abelechian, S., Brakebusch, C. & Brickman, J. M., 9 Aug 2016, In: Stem Cell Reports. 7, 2, p. 177-91 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

33 Citations (Scopus)

138 Downloads (Pure)

Implementation of a functional observation battery for the assessment of postoperative well-being in rats subjected to fimbria-fornix transections

Marschner, L., Wogensen, E., Mogensen, J. & Abelson, K., 1 Mar 2016, In: In Vivo. 30, 2, p. 77-82

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber)

Jørgensen, K. B., Krogh-Jensen, K., Pickering, D. S., Kanui, T. & Abelson, K., 1 Jan 2016, In: Journal of Comparative Physiology A. Sensory, neural, and behavioral physiology. 202, 1, p. 7-15 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

79 Downloads (Pure)

Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?

Olsen, H. G., Kjeldgaard-Hansen, M., Tveden-Nyborg, P., Birck, M. M., Hammelev, K. P., Vegge, A., Aalbæk, B., Leifsson, P. S., Jensen, H. E., Iburg, T., Heegaard, P. M. H. & Nielsen, O. L., 16 Feb 2016, In: BMC Research Notes. 9, p. 1-10 10 p., 99.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

80 Downloads (Pure)

Myocardial perfusion of infarcted and normal myocardium in propofol-anesthetized minipigs using ⁸²Rubidium PET

Rasmussen, T., Larsen, B. F., Kastrup, J., Christensen, T. E., Hammelev, K. P., Kjær, A. & Hasbak, P., 1 Jun 2016, In: Journal of Nuclear Cardiology. 23, 3, p. 599-603 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Protective Effect of Chronic Schistosomiasis in Baboons Coinfected with Schistosoma mansoni and Plasmodium knowlesi

Nyakundi, R. K., Nyamongo, O., Maamun, J., Akinyi, M., Mulei, I., Farah, I. O., Blankenship, DA., Grimberg, B., Hau, J., Malhotra, I., Ozwara, H., King, C. L. & Kariuki, T. M., 1 May 2016, In: Infection and Immunity. 84, 5, p. 1320-30 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Robust retention and transfer of tool construction techniques in chimpanzees (Pan troglodytes)

Vale, G. L., Flynn, E. G., Pender, L., Price, E., Whiten, A., Lambeth, S. P., Schapiro, S. & Kendal, R. L., 1 Feb 2016, In: Journal of Comparative Psychology. 130, 1, p. 24-35 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

Hansen, R. K., Mund, A., Poulsen, S. L., Sandoval, M., Klement, K., Tsouroula, K., Tollenaere, M. A. X., Räschle, M., Soria, R., Offermanns, S., Worzfeld, T., Grosse, R., Brandt, D. T., Rozell, B., Mann, M., Cole, F., Soutoglou, E., Goodarzi, A. A., Daniel, J. A., Mailand, N., & 1 othersBekker-Jensen, S., 1 Dec 2016, In: Nature Cell Biology. 18, 12, p. 1357–1366

Research output: Contribution to journal › Letter › peer-review

14 Citations (Scopus)

146 Downloads (Pure)

The Effect of Induced Antibodies with Respect to Neutralization, Clearance Rate and Functional Activity in a Rabbit/Infliximab Model

Henriksen, M. L., Teisner, A., Kjeldsen, J., Kalliokoski, O., Hau, J. & Hansen, S. W. K., Sept 2016, In: In Vivo. 30, 5, p. 557-565 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Welfare indicators in laying hens in relation to nest exclusion

Alm, M., Tauson, R., Holm, L., Wichman, A., Kalliokoski, O. & Wall, H., 1 Jun 2016, In: Poultry Science. 95, 6, p. 1238-1247 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

2015

Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses

Haugaard, M. M., Pehrson, S., Carstensen, H., Madsen, M. F., Hesselkilde, E. Z., Præstegaard, K. F., Diness, J. G., Grunnet, M., Jespersen, T. & Buhl, R., 1 Jan 2015, In: Journal of Veterinary Internal Medicine. 29, 1, p. 339-347 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

1434 Downloads (Pure)

Chimpanzees copy dominant and knowledgeable individuals: implications for cultural diversity

Kendal, R., Hopper, L. M., Whiten, A., Brosnan, S. F., Lambeth, S. P., Schapiro, S. & Hoppitt, W., 1 Jan 2015, In: Evolution and Human Behavior. 36, 1, p. 65-72 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

107 Citations (Scopus)

Contribution of Lipocalin-2 from Both Myeloid Cells and Epithelium/Liver Is Required for Optimal Resistance to K. Pneumonia Infection

Cramer, E. P., Dahl, S. L., Rozell, B., Knudsen, K. J., Thomsen, K., Moser, C., Borregaard, N. & Cowland, J. B., 3 Dec 2015, In: Blood. 126, 23, p. 883-883 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Dynamic regulation of cerebral DNA repair genes by psychological stress

Forsberg, K., Aalling, N., Wörtwein, G., Loft, S., Møller, P., Hau, J., Hageman, I., Jørgensen, M. B. & Jørgensen, A., 5 Jan 2015, In: Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 778, p. 37-43 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

ESTABLISHING A BEHAVIORAL MANAGEMENT PROGRAM FOR GERIATRIC CHIMPANZEES

Bridges, J. P., Haller, R. L., Buchl, S. J., Magden, E. R., Lambeth, S. P. & Schapiro, S. J., Nov 2015, In: American Journal of Primatology. 77, S1, p. 111-111 177.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior

Baek, J-H., Schmidt, E., Viceconte, N., Strandgren, C., Pernold, K., Richard, T. J. C., Van Leeuwen, F. W., Dantuma, N. P., Damberg, P., Hultenby, K., Ulfhake, B., Mugnaini, E., Rozell, B. & Eriksson, M., 1 Mar 2015, In: Human Molecular Genetics. 24, 5, p. 1305-1321 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

37 Downloads (Pure)

Neuroanatomical correlates of personality in chimpanzees (Pan troglodytes): Associations between personality and frontal cortex

Latzman, R. D., Hecht, L. K., Freeman, H. D., Schapiro, S. & Hopkins, W. D., 1 Dec 2015, In: NeuroImage. 123, p. 63-71

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses

Haugaard, M. M., Hesselkilde, E. Z., Pehrson, S. M., Carstensen, H., Madsen, M. F., Præstegaard, K. F., Sørensen, U. S., Diness, J. G., Grunnet, M., Buhl, R. & Jespersen, T., 1 Apr 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 4, p. 825-835 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

44 Citations (Scopus)

Selective and contagious prosocial resource donation in capuchin monkeys, chimpanzees and humans

Claidiere, N., Whiten, A., Mareno, M. C., Messer, E. J. E., Brosnan, S. F., Hopper, L. M., Lambeth, S. P., Schapiro, S. & McGuigan, N., 6 Jan 2015, In: Scientific Reports. 5, p. 1-11 7631.

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

44 Downloads (Pure)

Specific antibodies to Staphylococcus aureus biofilm are present in serum from pigs with osteomyelitis

Jensen, L. K., Jensen, H. E., Koch, J., Bjarnsholt, T., Eickhardt-Dalbøge, S. R. & Shirtliff, M., 1 Sept 2015, In: In Vivo. 29, p. 555-560 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

33 Downloads (Pure)

Suppressor of Fused Plays an Important Role in Regulating Mesodermal Differentiation of Murine Embryonic Stem Cells In Vivo

Hoelzl, M. A., Heby-Henricson, K., Bilousova, G., Rozell, B., Kuiper, R. V., Kasper, M., Toftgard, R. & Teglund, S., 1 Nov 2015, In: Stem Cells and Development. 24, 21, p. 2547-2560

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

The applicability of a gel delivery system for self-administration of buprenorphine to laboratory mice

Hovard, A. M. B., Teilmann, A. C., Hau, J. & Abelson, K. S. P., 1 Jan 2015, In: Laboratory Animals. 49, 1, p. 40-45 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

The distorting effect of varying diets on fecal glucocorticoid measurements as indicators of stress: A cautionary demonstration using laboratory mice

Kalliokoski, O., Teilmann, A. C., Abelson, K. S. P. & Hau, J., 5 Jan 2015, In: General and Comparative Endocrinology. 211, p. 147-153 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

The importance of witnessed agency in chimpanzee social learning of tool use

Hopper, L. M., Lambeth, S. P., Schapiro, S. & Whiten, A., 1 Mar 2015, In: Behavioural Processes. 112, p. 120-129

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

Transgene silencing of the Hutchinson-Gilford progeria syndrome mutation results in a reversible bone phenotype, whereas resveratrol treatment does not show overall beneficial effects

Strandgren, C., Nasser, H. A., McKenna, T., Koskela, A., Tuukkanen, J., Ohlsson, C., Rozell, B. & Eriksson, M., 1 Aug 2015, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29, 8, p. 3193-3205 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

2014

Age-related effects in the neocortical organization of chimpanzees: Gray and white matter volume, cortical thickness, and gyrification

Autrey, M. M., Reamer, L. A., Mareno, M. C., Sherwood, C. C., Herndon, J. G., Preuss, T., Schapiro, S. J. & Hopkins, W. D., 1 Nov 2014, In: NeuroImage. 101, p. 59-67 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Amyloid beta_1–42 and the phoshorylated tau threonine 231 in brains of aged cynomolgus monkeys (Macaca fascicularis)

Darusman, H. S., Gjedde, A., Sajuthi, D., Schapiro, S., Kalliokoski, O., Kristianingrum, Y. P., Handaryani, E. & Hau, J., Nov 2014, In: Frontiers in Aging Neuroscience. 6, p. 1-7 7 p., 313.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

An improved method for lifting and transporting anesthetized pigs within an animal facility

Schumacher-Petersen, C., Hammelev, K. P. & Flescher, J. E., Jul 2014, In: Lab Animal. 43, 7, p. 237-41 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Department of Experimental Medicine

Research output

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