Trond Ulven

Publikation

Publikationer pr. år 1996 2005 2009 2010 2012 2013 2014 2016 2017 2019

• 99 Tidsskriftartikel
• 20 Patent
• 3 Konferenceabstrakt til konference
• 2 Bidrag til bog/antologi
• 1 Mere
  • 1 Letter

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2012

  A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer

  Blättermann, S., Peters, L., Ottersbach, P. A., Bock, A., Konya, V., Weaver, C. D., Gonzalez, A., Schröder, R., Tyagi, R., Luschnig, P., Gäb, J., Hennen, S., Ulven, T., Pardo, L., Mohr, K., Gütschow, M., Heinemann, A. & Kostenis, E., jul. 2012, I: Nature Chemical Biology. 8, 7, s. 631-638 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Gue1654 100%
  • G-Protein-Coupled Receptors 80%
  • Arrestin 58%
  • Ligands 56%
  • Formyl Peptide Receptor 28%
  61 Citationer (Scopus)

• A concise synthesis of the potent inflammatory mediator 5-oxo-ETE

  Tyagi, R., Shimpukade, B., Blättermann, S., Kostenis, E. & Ulven, T., feb. 2012, I: MedChemComm. 3, s. 195-198 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 5-oxo-ETE(1-) 100%
  • 5-Oxo-ETE 82%
  • Arachidonic Acids 64%
  • Arachidonic Acid 47%
  • Reaction Yield 17%
  8 Citationer (Scopus)

• Antidiabetic enolic glucoside of phenylpyruvic acid.

  Joubert, E., Fey, S. J., Louw, J., Ulven, T. & Tyagi, R., 12 apr. 2012, Patentnr. WO 2012/045363A1

  Publikation: Patent

• Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

  Hudson, B. D., Christiansen, E., Tikhonova, I. G., Grundmann, M., Kostenis, E., Adams, D. R., Ulven, T. & Milligan, G., dec. 2012, I: F A S E B Journal. 26, 12, s. 4951-4965 15 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Nonesterified Fatty Acids 100%
  • human G-protein coupled receptor 43 77%
  • Ligands 67%
  • Pharmacology 63%
  • Ligand 41%
  58 Citationer (Scopus)

• Discovery of a potent and selective GPR120 agonist

  Shimpukade, B., Hudson, B. D., Hovgaard, C. K., Milligan, G. & Ulven, T., 10 maj 2012, I: Journal of Medicinal Chemistry. 55, 9, s. 4511-4515 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Receptor Modulator 100%
  • Antiobesity 96%
  • Long-Chain Fatty Acid 77%
  • Glucagon-Like Peptide 1 74%
  • Sensitization 67%
  112 Citationer (Scopus)

• Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3

  Hudson, B. D., Tikhonova, I. G., Pandey, S. K., Ulven, T. & Milligan, G., 30 nov. 2012, I: Journal of Biological Chemistry. 287, 49, s. 41195-41209 15 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Volatile Fatty Acids 100%
  • Nonesterified Fatty Acids 99%
  • Ligands 66%
  • Ligand 41%
  • Agonist 30%
  73 Citationer (Scopus)

• Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonists

  Christiansen, E., Due-Hansen, M. E., Urban, C., Grundmann, M., Schröder, R., Hudson, B. D., Milligan, G., Cawthorne, M. A., Kostenis, E., Kassack, M. U. & Ulven, T., 2012, I: Journal of Medicinal Chemistry. 55, 14, s. 6624-6628 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • TUG-469 100%
  • TAK-875 81%
  • Nonesterified Fatty Acids 44%
  • Agonist 40%
  • Type 2 Diabetes Mellitus 31%
  45 Citationer (Scopus)

• Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors

  Thiele, S., Malmgaard-Clausen, M., Engel-Andreasen, J., Steen, A., Rummel, P. C., Nielsen, M. C., Gloriam, D. E., Frimurer, T. M., Ulven, T. & Rosenkilde, M., 27 sep. 2012, I: Journal of Medicinal Chemistry. 55, 18, s. 8164-77 14 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • CCR Receptors 100%
  • Chemokine Receptors 73%
  • 2,2'-Dipyridyl 54%
  • 1,10-phenanthroline 48%
  • Ligands 46%
  23 Citationer (Scopus)

• PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2

  Schröder, R., Xue, L., Konya, V., Martini, L., Kampitsch, N., Whistler, J. L., Ulven, T., Heinemann, A., Pettipher, R. & Kostenis, E., 19 mar. 2012, I: P L o S One. 7, 3, s. e33329

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Prostaglandins 100%
  • Prostaglandins H 98%
  • Metabolites 68%
  • Precursor 67%
  • Receptor 64%
  10 Citationer (Scopus)

• Preparation of ortho-fluoro substituted compounds for the treatment of metabolic diseases.

  Ulven, T. & Christiansen, E., 11 okt. 2012, Patentnr. WO 2012/136221A1

  Publikation: Patent

• Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets

  Ulven, T., 2012, I: Frontiers in Endocrinology. 3

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Volatile Fatty Acids 100%
  • Nonesterified Fatty Acids 82%
  • Metabolic Diseases 20%
  • Neutrophils 15%
  • Drug Receptors 13%
  147 Citationer (Scopus)

• Tetrasubstituted phenanthrolines as highly potent, water-soluble, and selective g-quadruplex ligands

  Larsen, A. F., Nielsen, M. C. & Ulven, T., 27 aug. 2012, I: Chemistry: A European Journal. 18, 35, s. 10892-10902 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Lead compounds 100%
  • Phenanthrolines 93%
  • Ligands 78%
  • Solubility 64%
  • DNA 61%
  24 Citationer (Scopus)

• The oxygen-mediated synthesis of 1,3-butadiynes in continuous flow

  Petersen, T. P., Polyzos, A., O'Brien, M., Ulven, T., Baxendale, I. R. & Ley, S. V., 2012, I: ChemSusChem (Print). 5, 2, s. 274-277 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  90 Citationer (Scopus)
• 2011

  Conjugated Linoleic Acids Mediate Insulin Release through Islet G Protein-coupled Receptor FFA1/GPR40

  Schmidt, J., Liebscher, K., Merten, N., Grundmann, M., Mielenz, M., Sauerwein, H., Christiansen, E., Due-Hansen, M. E., Ulven, T., Ullrich, S., Gomeza, J., Drewke, C. & Kostenis, E., 8 apr. 2011, I: Journal of Biological Chemistry. 286, 14, s. 11890-11894 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Conjugated Linoleic Acids 100%
  • Conjugated Linoleic Acid 98%
  • Insulin Derivative 68%
  • G-Protein-Coupled Receptors 67%
  • Insulin 45%
  47 Citationer (Scopus)

• Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides

  Larsen, A. F. & Ulven, T., 1 jul. 2011, I: Organic Letters. 13, 13, s. 3546-3548 3 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 1,10-phenanthroline-2,9-dicarboxylic acid 100%
  • dicarboxylic acids 65%
  • G-Quadruplexes 56%
  • synthesis 27%
  • Acid 13%
  34 Citationer (Scopus)

• Extracellular loop 2 of the free Fatty Acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator

  Smith, N. J., Ward, R. J., Stoddart, L. A., Hudson, B. D., Kostenis, E., Ulven, T., Morris, J. C., Tränkle, C., Tikhonova, I. G., Adams, D. R. & Milligan, G., jul. 2011, I: Molecular Pharmacology. 80, 1, s. 163-173 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Nonesterified Fatty Acids 100%
  • Structure-Activity Relationship 74%
  • Ligands 67%
  • Binding Sites 49%
  • Allosteric Site 45%
  56 Citationer (Scopus)

• Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties

  Christiansen, E., Urban, C., Grundmann, M., Due-Hansen, M. E., Hagesaether, E., Schmidt, J., Pardo, L., Ullrich, S., Kostenis, E., Kassack, M. U. & Ulven, T., 13 okt. 2011, I: Journal of Medicinal Chemistry. 54, 19, s. 6691-6703 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Nonesterified Fatty Acids 100%
  • Agonist 91%
  • Thiazolidinediones 62%
  • Insulinoma 60%
  • Insulin Secretion 47%
  58 Citationer (Scopus)

• Method of synthesizing a 5-oxo-conjugated fatty acid

  Ulven, T. & Tyagi, R., 27 okt. 2011, Patentnr. WO 2011/131619 A1

  Publikation: Patent

• Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3

  Schmidt, J., Smith, N. J., Christiansen, E., Tikhonova, I. G., Grundmann, M., Hudson, B. D., Ward, R. J., Drewke, C., Milligan, G., Kostenis, E. & Ulven, T., 25 mar. 2011, I: Journal of Biological Chemistry. 286, 12, s. 10628-10640 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Nonesterified Fatty Acids 100%
  • Agonist 91%
  • Ligands 40%
  • Short-Chain Fatty Acid 40%
  • Volatile Fatty Acids 36%
  82 Citationer (Scopus)
• 2010

  A Rapid and Efficient Sonogashira Protocol and Improved Synthesis of Free Fatty Acid 1 (FFA1) Receptor Agonists

  Christiansen, E., Due-Hansen, M. E. & Ulven, T., 19 feb. 2010, I: Journal of Organic Chemistry. 75, 4, s. 1301-1304 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Sonogashira Cross-Coupling 100%
  • Agent Interacting With Transmitter, Hormone or Drug Receptor 97%
  • Ligand 38%
  • Alkyne 37%
  • Iodide 34%
  13 Citationer (Scopus)

• Compounds for the treatment of metabolic diseases

  Ulven, T. & Christiansen, E., 4 feb. 2010, Patentnr. WO 2010/012650

  Publikation: Patent

• Macrocyclic G-quadruplex ligands

  Nielsen, M. C. & Ulven, T., 1 jan. 2010, I: Current Medicinal Chemistry. 17, 29, s. 3438-3448 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • G-Quadruplexes 100%
  • Ligands 48%
  • telomestatin 34%
  • Telomestatin 31%
  • Ligand 29%
  43 Citationer (Scopus)

• Novel CRTH2 antagonists: a review of patents from 2006 to 2009

  Ulven, T. & Kostenis, E., 1 nov. 2010, I: Expert Opinion on Therapeutic Patents. 20, 11, s. 1505-1530 26 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Patents 100%
  • Antagonist 76%
  • Prostaglandins D 29%
  • Atopic Dermatitis 28%
  • Chronic Obstructive Pulmonary Disease 24%
  44 Citationer (Scopus)

• Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2

  Grimstrup, M., Rist, Ø., Receveur, J-M., Frimurer, T. M., Ulven, T., Mathiesen, J. M., Kostenis, E. & Högberg, T., 1 feb. 2010, I: Bioorganic & Medicinal Chemistry Letters. 20, 3, s. 1181-1185 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Thiazoles 100%
  • Chemoattractant 94%
  • Thiazole 71%
  • Computer Simulation 61%
  • Antagonist 59%
  14 Citationer (Scopus)

• Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469

  Christiansen, E., Due-Hansen, M. E., Urban, C., Merten, N., Pfleiderer, M., Karlsen, K. K., Rasmussen, S. S., Steensgaard, M., Hamacher, A., Schmidt, J., Drewke, C., Petersen, R. K., Kristiansen, K., Ullrich, S., Kostenis, E., Kassack, M. U. & Ulven, T., 14 okt. 2010, I: ACS Medicinal Chemistry Letters. 1, 7, s. 345-349 5 s.

  Publikation: Bidrag til tidsskrift › Letter › peer review

  • TUG-469 100%
  • 3-phenylpropionic acid 80%
  • Structure-Activity Relationship 49%
  • Nonesterified Fatty Acids 44%
  • Insulin Secretion 41%
  54 Citationer (Scopus)

• Targeting the prostaglandin D2 receptors DP1 and CRTH2 for treatment of inflammation

  Ulven, T. & Kostenis, E., 2010, Frontiers in Medicinal Chemistry. Bentham Science Publishers, Bind 5.

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

  • prostaglandin D2 receptor 100%
  • Prostaglandin D2 40%
  • Inflammation 35%
  • Asthma 23%
  • Pharmaceutical Chemistry 20%
  2 Citationer (Scopus)
• 2009

  1,2-Dihydrospiro[carbazole-3(4H),2'-[1,3]dioxolane]

  Bjerrum, J. V., Ulven, T. & Bond, A., 2009, I: Acta Crystallographica. Section E: Structure Reports Online. 65, s. o579

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• 4-Fluoro-N-methyl-N-(1,2,3,4-tetrahydrocarbazol-3-yl)benzenesulfonamide

  Rasmussen, K. G., Ulven, T. & Bond, A., 2009, I: Acta Crystallographica. Section E: Structure Reports Online. 65, s. o742

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• A multistep continuous-flow system for rapid on-demand synthesis of receptor ligands

  Petersen, T. P., Ritzén, A. & Ulven, T., 19 nov. 2009, I: Organic Letters. 11, 22, s. 5134-5137 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Isocyanates 100%
  • Diamines 92%
  • Alkylating Agents 76%
  • Alkylating Agent 76%
  • Isocyanate 65%
  41 Citationer (Scopus)

• Cyclopropyl and cyclobutyl epothilone analogs

  Nicolaou, K. C., Namoto, K., Ritzén, A., Ulven, T., Shoji, M. & Altmann, K-H., 2009, Patentnr. EP 1,420,780 B1

  Publikation: Patent

• Design, synthesis and evaluation of 4,7-diamino-1,10-phenanthroline G-quadruplex ligands

  Nielsen, M. C., Borch, J. & Ulven, T., 15 dec. 2009, I: Bioorganic & Medicinal Chemistry. 17, 24, s. 8241-8246 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 1,10-phenanthroline 100%
  • G-Quadruplexes 99%
  • Phenanthroline 75%
  • Guanidine 70%
  • Surface Plasmon Resonance 64%
  23 Citationer (Scopus)

• Discovery and structure-activity relationship investigations of 4-arylethynyldihydrocinnamic acid agonists of the antidiabetic target free fatty acid receptor 1

  Christiansen, E., Urban, C., Merten, N., Liebscher, K., Karlsen, K. K., Hamacher, A., Spinrath, A., Bond, A., Drewke, C., Ullrich, S., Kassack, M. U., Kostenis, E. & Ulven, T., 2009.

  Publikation: Konferencebidrag › Konferenceabstrakt til konference › Forskning › peer review

• Ethyl 2-(1,2,3,4-tetrahydrospiro[carbazole-3,2'- [1,3]dioxolan]-9-yl)acetate

  Loffler, P., Ulven, T. & Bond, A., 2009, I: Acta Crystallographica. Section E: Structure Reports Online. 65, Section E, s. o685

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Extraction of G-quadruplex ligands from disulfide-based dynamic combinatorial libraries

  Nielsen, M. C. & Ulven, T., 2009, s. ORGN-345.

  Publikation: Konferencebidrag › Konferenceabstrakt til konference › Forskning › peer review

• Flow chemistry methods for the synthesis chemokine receptor ligands

  Petersen, T. P., Ritzén, A. & Ulven, T., 2009, s. ORGN-570.

  Publikation: Konferencebidrag › Konferenceabstrakt til konference › Forskning › peer review

• Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 1

  Rist, O., Grimstrup, M., Receveur, J-M., Frimurer, T. M., Ulven, T., Kostenis, E. & Högberg, T., 4 dec. 2009, I: Bioorganic & Medicinal Chemistry Letters. 20, 3, s. 1177-1180 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • prostaglandin D2 receptor 100%
  • Formyl Peptide Receptor 87%
  • Th2 Cells 71%
  • Structure-Activity Relationship 70%
  • Acetic Acid 65%
  12 Citationer (Scopus)

• The C-terminal tail of CRTH2 is a key molecular determinant that constrains GalphaI- and downstream-signaling cascade activation

  Schroeder, R., Merten, N., Mathiesen, J. M., Martini, L., Letunic, A. K., Krop, F., Blaukat, A., Fang, Y., Tran, E., Ulven, T., Drewke, C., Whistler, J., Pardo, L., Gomeza, J. & Kostenis, E., 2009, I: Journal of Biological Chemistry. 284, 2, s. 1324-1336 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • GTP-Binding Proteins 100%
  • Tail 64%
  • Prostaglandins D 51%
  • Protein 41%
  • Asthma 25%
  51 Citationer (Scopus)
• 2008

  Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes

  Christiansen, E., Urban, C., Merten, N., Liebscher, K., Karlsen, K. K., Hamacher, A., Spinrath, A., Bond, A. D., Drewke, C., Ullrich, S., Kassack, M. U., Kostenis, E. & Ulven, T., 27 nov. 2008, I: Journal of Medicinal Chemistry. 51, 22, s. 7061-4 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • TUG424 100%
  • Nonesterified Fatty Acids 88%
  • Agonist 80%
  • compound 20 66%
  • Type 2 Diabetes Mellitus 63%
  106 Citationer (Scopus)

• Positive versus negative modulation of different endogenous chemokines for CC-chemokine receptor 1 by small molecule agonists through allosteric versus orthosteric binding

  Jensen, P. C., Thiele, S., Ulven, T., Schwartz, T. W. & Rosenkilde, M. M., 17 jun. 2008, I: Journal of Biological Chemistry. 283, 34, s. 23121-23128 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • CCR1 Receptors 100%
  • Agonist 55%
  • Chemokines 54%
  • Ligands 40%
  • Enhancer 34%

• Selective extraction of G-quadruplex ligands from a rationally designed scaffold-based dynamic combinatorial library

  Nielsen, M. C. & Ulven, T., 1 jan. 2008, I: Chemistry: A European Journal. 14, 31, s. 9487-9490 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Ligands 100%
  • Combinatorial Library 91%
  • Scaffolds 89%
  • Ligand 33%
  14 Citationer (Scopus)
• 2007

  A novel antagonist of CRTH2 blocks eosinophil release from bone marrow, chemotaxis and respiratory burst

  Royer, J. F., Schratl, P., Lorenz, S., Kostenis, E., Ulven, T., Schuligoi, R., Peskar, B. A. & Heinemann, A., 1 dec. 2007, I: Allergy. 62, 12, s. 1401-1409 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • CAY 10471 100%
  • Respiratory Burst 85%
  • Chemotaxis 74%
  • Eosinophils 67%
  • Bone Marrow 51%
  40 Citationer (Scopus)

• Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

  Uller, L., Mathiesen, J. M., Alenmyr, L., Korsgren, M., Ulven, T., Högberg, T., Andersson, G., Persson, C. G. A. & Kostenis, E., 1 feb. 2007, I: Respiratory Research. 8, 16

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • ramatroban 100%
  • prostaglandin D2 receptor 87%
  • Asthma 41%
  • Mucus 33%
  • Pathology 33%
  111 Citationer (Scopus)

• Phenoxyacetic acid derivatives as CRTH2 receptor ligands, their preparation, pharmaceutical compositions, and use in therapy

  Ulven, T., Frimurer, T. M., Rist, Ø., Kostenis, E., Högberg, T., Receveur, J-M. & Grimstrup, M., 2007, Patentnr. WO 2007/062678 A1

  Publikation: Patent

• Synthesis and in vitro evaluation of a selective antagonist and the corresponding radioligand for the prostaglandin D2 receptor CRTH2

  Ulven, T., Gallen, M. J., Nielsen, M. C., Merten, N., Schmidt, C., Mohr, K., Tränkle, C. & Kostenis, E., 1 nov. 2007, I: Bioorganic & Medicinal Chemistry Letters. 17, 21, s. 5924-5927 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • prostaglandin D2 receptor 100%
  • Prostaglandin D2 97%
  • Radioligand 67%
  • Radioactivity 59%
  • Antagonist 56%
  8 Citationer (Scopus)

• The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking

  Schratl, P., Royer, J. F., Kostenis, E., Ulven, T., Sturm, E. M., Waldhoer, M., Hoefler, G., Schuligoi, R., Lippe, I. T., Peskar, B. A. & Heinemann, A., 1 okt. 2007, I: Journal of Immunology. 179, 7, s. 4792-4799 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • prostaglandin D2 receptor 100%
  • Eosinophils 58%
  • Prostaglandins 56%
  • ramatroban 34%
  • Bone Marrow 26%
  56 Citationer (Scopus)

• Thiazole- and pyrimidineacetic acid derivatives as CRTH2 receptor ligands, their preparation, pharmaceutical compositions, and use in therapy

  Ulven, T., Frimurer, T. M., Rist, Ø., Kostenis, E., Högberg, T., Receveur, J-M. & Grimstrup, M., 2007, Patentnr. WO 2007/062677 A1

  Publikation: Patent
• 2006

  6-Acylamino-2-amino-4-methylquinolines as potent melanin-concentrating hormone 1 receptor antagonists

  Ulven, T., Little, P. B., Receveur, J-M., Frimurer, T. M., Rist, Ø., Nørregaard, P. K., Mathiesen, J. M. & Högberg, T., 2006, I: Bioorganic & Medicinal Chemistry Letters. 16, 4, s. 1070-1075 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  31 Citationer (Scopus)

• Emerging roles of DP and CRTH2 in allergic inflammation

  Kostenis, E. & Ulven, T., 2006, I: Trends in Molecular Medicine. 12, 4, s. 148-158 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  161 Citationer (Scopus)

• Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits

  Ulven, T., Receveur, J-M., Grimstrup, M., Rist, Ø., Frimurer, T. M., Gerlach, L-O., Mathiesen, J. M., Kostenis, E., Uller, L. & Högberg, T., 2006, I: Journal of Medicinal Chemistry. 49, 23, s. 6638-6641 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  36 Citationer (Scopus)

• On the mechanism of interaction of potent, surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2

  Mathiesen, J. M., Christopoulos, A., Ulven, T., Royer, J. F., Campillo, M., Heinemann, A., Pardo, L. & Kostenis, E., 2006, I: Molecular Pharmacology. 69, 4, s. 1441-1453 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  43 Citationer (Scopus)