Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469

Elisabeth Christiansen; Maria E. Due-Hansen; Christian Urban; Nicole Merten; Michael Pfleiderer; Kasper Kannegård Karlsen; Sanne S. Rasmussen; Mette Steensgaard; Alexandra Hamacher; Johannes Schmidt; Christel Drewke; Rasmus Koefoed Petersen; Karsten Kristiansen; Susanne Ullrich; Evi Kostenis; Matthias U. Kassack; Trond Ulven

doi:10.1021/ml100106c

Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469

Elisabeth Christiansen, Maria E. Due-Hansen, Christian Urban, Nicole Merten, Michael Pfleiderer, Kasper Kannegård Karlsen, Sanne S. Rasmussen, Mette Steensgaard, Alexandra Hamacher, Johannes Schmidt, Christel Drewke, Rasmus Koefoed Petersen, Karsten Kristiansen, Susanne Ullrich, Evi Kostenis, Matthias U. Kassack, Trond Ulven

Genomforskning og Molekylær Biomedicin

54 Citationer (Scopus)

Originalsprog	Engelsk
Tidsskrift	ACS Medicinal Chemistry Letters
Vol/bind	1
Udgave nummer	7
Sider (fra-til)	345-349
Antal sider	5
ISSN	1948-5875
DOI	https://doi.org/10.1021/ml100106c
Status	Udgivet - 14 okt. 2010

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Christiansen, E., Due-Hansen, M. E., Urban, C., Merten, N., Pfleiderer, M., Karlsen, K. K., Rasmussen, S. S., Steensgaard, M., Hamacher, A., Schmidt, J., Drewke, C., Petersen, R. K., Kristiansen, K., Ullrich, S., Kostenis, E., Kassack, M. U., & Ulven, T. (2010). Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469. ACS Medicinal Chemistry Letters, 1(7), 345-349. https://doi.org/10.1021/ml100106c

Christiansen, E, Due-Hansen, ME, Urban, C, Merten, N, Pfleiderer, M, Karlsen, KK, Rasmussen, SS, Steensgaard, M, Hamacher, A, Schmidt, J, Drewke, C, Petersen, RK, Kristiansen, K, Ullrich, S, Kostenis, E, Kassack, MU & Ulven, T 2010, 'Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469', ACS Medicinal Chemistry Letters, bind 1, nr. 7, s. 345-349. https://doi.org/10.1021/ml100106c

@article{1adfb57500394f2b95205e4c3989e744,

title = "Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469",

keywords = "Diabetes, FFA1, FFAR1, GPR40, fatty acids, drug discovery",

author = "Elisabeth Christiansen and Due-Hansen, {Maria E.} and Christian Urban and Nicole Merten and Michael Pfleiderer and Karlsen, {Kasper Kanneg{\aa}rd} and Rasmussen, {Sanne S.} and Mette Steensgaard and Alexandra Hamacher and Johannes Schmidt and Christel Drewke and Petersen, {Rasmus Koefoed} and Karsten Kristiansen and Susanne Ullrich and Evi Kostenis and Kassack, {Matthias U.} and Trond Ulven",

year = "2010",

month = oct,

day = "14",

doi = "10.1021/ml100106c",

language = "English",

volume = "1",

pages = "345--349",

journal = "ACS Medicinal Chemistry Letters",

issn = "1948-5875",

publisher = "American Chemical Society",

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T1 - Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469

AU - Christiansen, Elisabeth

AU - Due-Hansen, Maria E.

AU - Urban, Christian

AU - Merten, Nicole

AU - Pfleiderer, Michael

AU - Karlsen, Kasper Kannegård

AU - Rasmussen, Sanne S.

AU - Steensgaard, Mette

AU - Hamacher, Alexandra

AU - Schmidt, Johannes

AU - Drewke, Christel

AU - Petersen, Rasmus Koefoed

AU - Kristiansen, Karsten

AU - Ullrich, Susanne

AU - Kostenis, Evi

AU - Kassack, Matthias U.

AU - Ulven, Trond

PY - 2010/10/14

Y1 - 2010/10/14

KW - Diabetes

KW - FFA1

KW - FFAR1

KW - GPR40

KW - fatty acids

KW - drug discovery

U2 - 10.1021/ml100106c

DO - 10.1021/ml100106c

M3 - Letter

C2 - 24900217

SN - 1948-5875

VL - 1

SP - 345

EP - 349

JO - ACS Medicinal Chemistry Letters

JF - ACS Medicinal Chemistry Letters

IS - 7

ER -

Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469

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