Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides

Anders Foller Larsen; Trond Ulven

doi:10.1021/ol201321z

Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides

Anders Foller Larsen, Trond Ulven

34 Citationer (Scopus)

Abstract

A convenient and high-yielding multigram synthesis of the versatile intermediate 4,7-dichloro-1,10-phenanthroline-2,9-dicarboxylic acid is described. The intermediate is further efficiently derivatized to 4,7-diamino-1,10-phenanthroline-2,9-dicarboxamides with potential G-quadruplex stabilizing effects.

Originalsprog	Engelsk
Tidsskrift	Organic Letters
Vol/bind	13
Udgave nummer	13
Sider (fra-til)	3546-3548
Antal sider	3
ISSN	1523-7060
DOI	https://doi.org/10.1021/ol201321z
Status	Udgivet - 1 jul. 2011

Adgang til dokumentet

10.1021/ol201321z

Citationsformater

@article{807cfafd50f1477ea87e4390b16d93ba,

title = "Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides",

abstract = "A convenient and high-yielding multigram synthesis of the versatile intermediate 4,7-dichloro-1,10-phenanthroline-2,9-dicarboxylic acid is described. The intermediate is further efficiently derivatized to 4,7-diamino-1,10-phenanthroline-2,9-dicarboxamides with potential G-quadruplex stabilizing effects.",

author = "Larsen, {Anders Foller} and Trond Ulven",

year = "2011",

month = jul,

day = "1",

doi = "10.1021/ol201321z",

language = "English",

volume = "13",

pages = "3546--3548",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "13",

}

TY - JOUR

T1 - Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides

AU - Larsen, Anders Foller

AU - Ulven, Trond

PY - 2011/7/1

Y1 - 2011/7/1

N2 - A convenient and high-yielding multigram synthesis of the versatile intermediate 4,7-dichloro-1,10-phenanthroline-2,9-dicarboxylic acid is described. The intermediate is further efficiently derivatized to 4,7-diamino-1,10-phenanthroline-2,9-dicarboxamides with potential G-quadruplex stabilizing effects.

AB - A convenient and high-yielding multigram synthesis of the versatile intermediate 4,7-dichloro-1,10-phenanthroline-2,9-dicarboxylic acid is described. The intermediate is further efficiently derivatized to 4,7-diamino-1,10-phenanthroline-2,9-dicarboxamides with potential G-quadruplex stabilizing effects.

U2 - 10.1021/ol201321z

DO - 10.1021/ol201321z

M3 - Journal article

SN - 1523-7060

VL - 13

SP - 3546

EP - 3548

JO - Organic Letters

JF - Organic Letters

IS - 13

ER -

Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater