A concise synthesis of the potent inflammatory mediator 5-oxo-ETE

Rahul Tyagi; Bharat Shimpukade; Stefanie Blättermann; Evi Kostenis; Trond Ulven

A concise synthesis of the potent inflammatory mediator 5-oxo-ETE

Rahul Tyagi, Bharat Shimpukade, Stefanie Blättermann, Evi Kostenis, Trond Ulven

8 Citationer (Scopus)

Abstract

A concise and practical method for synthesis of the potent inflammatory mediator 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-oxo-ETE, 1) from arachidonic acid in four steps and 70% overall yield is reported. Stability studies indicate that 1 can be safely handled without rigorous precautions

Originalsprog	Engelsk
Tidsskrift	MedChemComm
Vol/bind	3
Sider (fra-til)	195-198
Antal sider	4
ISSN	2040-2503
Status	Udgivet - feb. 2012

Citationsformater

@article{9c3bdf72ff514f77a537cc101a47c2c4,

title = "A concise synthesis of the potent inflammatory mediator 5-oxo-ETE",

abstract = "A concise and practical method for synthesis of the potent inflammatory mediator 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-oxo-ETE, 1) from arachidonic acid in four steps and 70% overall yield is reported. Stability studies indicate that 1 can be safely handled without rigorous precautions",

keywords = "inflammatory mediator, 5-oxo-ETE",

author = "Rahul Tyagi and Bharat Shimpukade and Stefanie Bl{\"a}ttermann and Evi Kostenis and Trond Ulven",

year = "2012",

month = feb,

language = "English",

volume = "3",

pages = "195--198",

journal = "MedChemComm",

issn = "2040-2503",

publisher = "Royal Society of Chemistry",

}

TY - JOUR

T1 - A concise synthesis of the potent inflammatory mediator 5-oxo-ETE

AU - Tyagi, Rahul

AU - Shimpukade, Bharat

AU - Blättermann, Stefanie

AU - Kostenis, Evi

AU - Ulven, Trond

PY - 2012/2

Y1 - 2012/2

N2 - A concise and practical method for synthesis of the potent inflammatory mediator 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-oxo-ETE, 1) from arachidonic acid in four steps and 70% overall yield is reported. Stability studies indicate that 1 can be safely handled without rigorous precautions

AB - A concise and practical method for synthesis of the potent inflammatory mediator 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-oxo-ETE, 1) from arachidonic acid in four steps and 70% overall yield is reported. Stability studies indicate that 1 can be safely handled without rigorous precautions

KW - inflammatory mediator

KW - 5-oxo-ETE

M3 - Journal article

SN - 2040-2503

VL - 3

SP - 195

EP - 198

JO - MedChemComm

JF - MedChemComm

ER -

A concise synthesis of the potent inflammatory mediator 5-oxo-ETE

Abstract

Fingeraftryk

Citationsformater