Rune Ehrenreich Kuhre

Publikation

Publikationer pr. år 2011 2014 2015 2016 2017 2019 2019

• 31 Tidsskriftartikel
• 2 Encyclopædiartikel
• 2 Konferenceabstrakt i tidsskrift
• 1 Review

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2019

  Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine

  Booz, V., Christiansen, C. B., Kuhre, R. E., Saltiel, M. Y., Sociali, G., Schaltenberg, N., Fischer, A. W., Heeren, J., Zocchi, E., Holst, J. J. & Bruzzone, S., 1 feb. 2019, I: Diabetes - Metabolism: Research and Reviews (Print Edition). 35, 8 s., e3102.

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  • Abscisic Acid 100%
  • Glucagon-Like Peptide 1 68%
  • Intestines 52%
  • Pancreas 50%
  • Insulin 39%
  3 Citationer (Scopus)

• Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients

  Vestergaard, E. T., Hjelholt, A. J., Kuhre, R. E., Møller, N., Larraufie, P., Gribble, F. M., Reimann, F., Jessen, N., Holst, J. J. & Jørgensen, J. O. L., 21 mar. 2019, I: The Journal of clinical endocrinology and metabolism. 104, 7, s. 2581-2592

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  • acipimox 100%
  • Glucagon-Like Peptide 1 91%
  • Overweight 51%
  • Nonesterified Fatty Acids 24%
  • Hormone 19%
  5 Citationer (Scopus)

• Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents

  Christiansen, C. B., Trammell, S. A. J., Albrechtsen, N. J. W., Schoonjans, K., Albrechtsen, R., Gillum, M. P., Kuhre, R. E. & Holst, J. J., maj 2019, I: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, s. G574-G584 11 s.

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  • Peptide YY 100%
  • Glucagon-Like Peptide 1 82%
  • Bile Acids and Salts 73%
  • Rodentia 58%
  • Colon 33%
  15 Citationer (Scopus)

  1 Downloads (Pure)

• Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine

  Kuhre, R. E. & Holst, J. J., 26 feb. 2019, I: Journal of Visualized Experiments. 144, e58533.

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  • Gastrointestinal Hormone 100%
  • Hormones 83%
  • Rats 68%
  • Small Intestine 52%
  • Intestinal Absorption 22%
  2 Citationer (Scopus)

  1 Downloads (Pure)

• Neuromedin U Does Not Act as a Decretin in Rats

  Kuhre, R. E., Christiansen, C. B., Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, I. M., Mandrup-Poulsen, T., Albrechtsen, R., Rosenkilde, M. M., Hartmann, B., Albrechtsen, N. J. W. & Holst, J. J., 2019, I: Cell Metabolism. 29, 3, s. 719-726.e1-e5 13 s.

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  • neuromedin U 100%
  • Insulin Secretion 24%
  • Hormones 23%
  • Pancreas 21%
  • Glucagon-Like Peptide 1 19%
  5 Citationer (Scopus)

  15 Downloads (Pure)

• No direct effect of SGLT2 activity on glucagon secretion

  Kuhre, R. E., Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, N. J. W., Andersen, D. B., Aivazidis, A., Chen, L., Mandrup-Poulsen, T., Ørskov, C., Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, J. J., 1 jun. 2019, I: Diabetologia. 62, 6, s. 1011-1023

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  • Glucagon 100%
  • Sodium-Glucose Transporter 2 55%
  • Somatostatin-Secreting Cells 41%
  • Glucose 40%
  • Methylglucosides 33%
  40 Citationer (Scopus)

• Peptone-mediated glucagon-like peptide-1 secretion depends on intestinal absorption and activation of basolaterally located Calcium-Sensing Receptors

  Modvig, I. M., Kuhre, R. E. & Holst, J. J., apr. 2019, I: Physiological Reports. 7, 8, 13 s., e14056.

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  10 Citationer (Scopus)

  29 Downloads (Pure)
• 2018

  Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice

  Christiansen, C. B., Lind, S. J., Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, R. E., Hartmann, B., Mandrup-Poulsen, T., Deacon, C. F., Albrechtsen, N. J. W. & Holst, J. J., jul. 2018, I: Physiological Reports. 6, 13, s. 1-8 e13788.

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  • Glucagon-Like Peptide 1 100%
  • Interleukin-6 65%
  • Glucagon 38%
  • Insulin Secretion 36%
  • Glucose 30%
  2 Citationer (Scopus)

  46 Downloads (Pure)

• Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.

  Kuhre, R. E., Albrechtsen, N. J. W., Larsen, O., Jepsen, S. L., Balk-Møller, E., Andersen, D. B., Deacon, C. F., Schoonjans, K., Reimann, F., Gribble, F. M., Albrechtsen, R., Hartmann, B., Rosenkilde, M. & Holst, J. J., 2018, I: Molecular Metabolism. 11, s. 84-95 12 s.

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  • Ghrelin 100%
  • Bile Acids and Salts 87%
  • Pancreas 71%
  • GTP-Binding Proteins 47%
  • Glucagon-Like Peptide 1 42%
  60 Citationer (Scopus)

  60 Downloads (Pure)
• 2017

  Abscisic acid controls the release of insulin from beta-cells, Glucagon-Like Peptide-1 from intestinal L-cells and glucagon from alpha-cells

  Booz, V., Christiansen, C. B., Kuhre, R. E., Saltiel, M. Y., Sturla, L., Sociali, G., Zocchi, E., Holst, J. J. & Bruzzone, S., 2017, I: European Journal of Clinical Investigation. 47, s. 112-113

  Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning

• A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

  Wewer Albrechtsen, N. J., Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, R. E., Asmar, M., Veedfald, S., Plamboeck, A., Knop, F. K., Vilsbøll, T., Madsbad, S., Nauck, M. A., Deacon, C. F., Bülow, J., Holst, J. J. & Hartmann, B., 1 sep. 2017, I: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, s. E284-E291

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glucagon-Like Peptide 1 100%
  • Enzyme-Linked Immunosorbent Assay 60%
  • Type 2 Diabetes Mellitus 12%
  • Dipeptidyl Peptidase 4 11%
  • Dipeptidyl-Peptidase IV Inhibitors 11%
  6 Citationer (Scopus)

• Chenodeoxycholic acid stimulates glucagon-like peptide-1 secretion in patients after Roux-en-Y gastric bypass

  Nielsen, S., Svane, M. S., Kuhre, R. E., Clausen, T. R., Kristiansen, V. B., Rehfeld, J. F., Holst, J. J., Madsbad, S. & Bojsen-Moller, K. N., 1 feb. 2017, I: Physiological Reports. 5, 3, 11 s., e13140.

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  • Chenodeoxycholic Acid 100%
  • Glucagon-Like Peptide 1 83%
  • Gastric Bypass 82%
  • Bile Acids and Salts 74%
  • Ursodeoxycholic Acid 47%
  26 Citationer (Scopus)

  53 Downloads (Pure)

• Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

  Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N., & 9 flereIdorn, T., Deacon, C. F., Knop, F. K., Rosenkilde, M. M., Hartmann, B., Feldt-Rasmussen, B., Mann, M., Madsbad, S. & Holst, J. J., 7 nov. 2017, I: Cell Reports. 21, 6, s. 1452-1460

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  • Proglucagon 100%
  • Glucagon 85%
  • Insulin Derivative 64%
  • Insulin Secretion 62%
  • Blood Glucose 52%
  13 Citationer (Scopus)

  119 Downloads (Pure)

• On the relationship between glucose absorption and glucose‐stimulated secretion of GLP‐1, neurotensin, and PYY from different intestinal segments in the rat

  Kuhre, R. E., Christiansen, C. B., Saltiel, M. Y., Albrechtsen, N. J. W. & Holst, J. J., 3 dec. 2017, I: Physiological Reports. 5, 23, 13 s., e13507.

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  • Neurotensin 100%
  • Glucagon-Like Peptide 1 53%
  • Peptides 48%
  • Glucose 47%
  • Colon 30%
  21 Citationer (Scopus)

  73 Downloads (Pure)

• Sweet Taste Receptor Activation in the Gut Is of Limited Importance for Glucose-Stimulated GLP-1 and GIP Secretion

  Saltiel, M. Y., Kuhre, R. E., Christiansen, C. B., Eliasen, R., Conde-Frieboes, K. W., Rosenkilde, M. M. & Holst, J. J., 22 apr. 2017, I: Nutrients. 9, 4, 15 s., 418.

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  • Gastric Inhibitory Polypeptide 100%
  • glucagon-like peptide 1 99%
  • taste receptors 91%
  • Glucagon-Like Peptide 1 79%
  • trichlorosucrose 75%
  16 Citationer (Scopus)

  68 Downloads (Pure)

• Why is it so difficult to measure glucagon-like peptide-1 in a mouse?

  Windeløv, J. A., Wewer Albrechtsen, N. J., Kuhre, R. E., Jepsen, S. L., Hornburg, D., Pedersen, J., Jensen, E. P., Galsgaard, K. D., Winther-Sørensen, M., Ørgaard, A., Deacon, C. F., Mann, M., Kissow, H., Hartmann, B. & Holst, J. J., 1 okt. 2017, I: Diabetologia. 60, 10, s. 2066-2075 10 s.

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  • Glucagon-Like Peptide 1 100%
  • Enzyme-Linked Immunosorbent Assay 26%
  • candoxatril 21%
  • Dipeptidyl Peptidase 4 14%
  • Peptide Fragments 7%
  22 Citationer (Scopus)
• 2016

  Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.

  Albrechtsen, N. J. W., Kuhre, R. E., Windeløv, J. A., Ørgaard, A., Deacon, C. F., Kissow, H., Hartmann, B. & Holst, J. J., 1 aug. 2016, I: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, s. E302-E309 8 s.

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  • Glucagon 100%
  • Enzyme-Linked Immunosorbent Assay 67%
  • Arginine 53%
  • Hypnorm 38%
  • Glucose 36%
  16 Citationer (Scopus)

• Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes

  Albrechtsen, N. J. W., Albrechtsen, R., Bremholm, L., Svendsen, B., Kuhre, R. E., Poulsen, S. S., Christiansen, C. B., Jensen, E. P., Janus, C., Hilsted, L., Deacon, C. F., Hartmann, B. & Holst, J. J., 13 dec. 2016, I: Cell Reports. 17, 11, s. 2845-2856 13 s.

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  • Glucagon-Like Peptide 1 100%
  • Glucagon-Like Peptide-1 Receptor 81%
  • Acinar Cells 74%
  • Exocrine Pancreas 62%
  • Incretins 41%
  15 Citationer (Scopus)

  553 Downloads (Pure)

• Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma

  Wewer Albrechtsen, N. J., Hornburg, D., Albrechtsen, R., Svendsen, B., Toräng, S., Jepsen, S. L., Kuhre, R. E., Hansen, M., Janus, C., Floyd, A., Lund, A., Lauritsen, T. V., Knop, F. K., Vestergaard, H., Deacon, C. F., Meissner, F., Mann, M., Holst, J. J. & Hartmann, B., 1 maj 2016, I: EBioMedicine. 7, s. 112-120 9 s.

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  • Oxyntomodulin 100%
  • Gastrointestinal Hormone 67%
  • Glucagon-Like Peptide 1 62%
  • Gastric Bypass 60%
  • Mass Spectrometry 47%
  37 Citationer (Scopus)

• Peptide production and secretion in GLUTag, NCI-H716 and STC-1 cells: a comparison to native L-cells.

  Kuhre, R. E., Albrechtsen, N. J. W., Deacon, C. F., Balk-Møller, E., Rehfeld, J. F., Relman, F., Gribble, F. M. & Holst, J. J., apr. 2016, I: Journal of Molecular Endocrinology. 56, s. 201-211

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  • L Cells 100%
  • Glucagon-Like Peptide 1 89%
  • Proprotein Convertase 1 50%
  • Peptides 48%
  • Cell Line 36%
  48 Citationer (Scopus)

• The biology of glucagon and the consequences of hyperglucagonemia

  Wewer Albrechtsen, N. J., Kuhre, R. E., Pedersen, J., Knop, F. K. & Holst, J. J., nov. 2016, I: Biomarkers in Medicine. 10, 11, s. 1141-1151 11 s.

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  • Glucagon 100%
  • glucagon 29 39%
  • Proglucagon 29%
  • Glucose 27%
  • Amino Acids 25%
  40 Citationer (Scopus)

  175 Downloads (Pure)

• The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs

  Albrechtsen, N. J. W., Kuhre, R. E., Toräng, S. & Holst, J. J., 2 feb. 2016, I: BMC Research Notes. 9, 1, s. 1-6 6 s., 60.

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  • Glucagon-Like Peptide 1 100%
  • Glicentin 97%
  • Oxyntomodulin 90%
  • Peptide YY 81%
  • Neurotensin 69%
  36 Citationer (Scopus)

  52 Downloads (Pure)

• The regulation of function, growth and survival of GLP-1-producing L-cells.

  Kuhre, R. E., Holst, J. J. & Kappe, C., 1 jan. 2016, I: Clinical Science. 130, 2, s. 79-91 13 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • L Cells 100%
  • Glucagon-Like Peptide 1 89%
  • Growth 38%
  • Cell Survival 12%
  • Overnutrition 12%
  22 Citationer (Scopus)
• 2015

  Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors

  Brighton, C. A., Rievaj, J., Kuhre, R. E., Glass, L. L., Schoonjans, K., Holst, J. J., Gribble, F. M. & Reimann, F., nov. 2015, I: Endocrinology. 156, 11, s. 3961-1370 10 s.

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  • Taurodeoxycholic Acid 100%
  • Glucagon-Like Peptide 1 96%
  • Taurodeoxycholate 93%
  • Bile Acid 70%
  • Bile Acids and Salts 63%
  157 Citationer (Scopus)

• Glucose stimulates neurotensin secretion from the rat small intestine by mechanisms involving SGLT1 and GLUT2 leading to cell depolarization and calcium influx

  Kuhre, R. E., Bechmann, L. E., Hartmann, B., Albrechtsen, N. J. W. & Holst, J. J., 15 jun. 2015, I: American Journal of Physiology: Endocrinology and Metabolism. 308, 12, s. E1123–E1130 8 s.

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  • Sodium-Glucose Transporter 1 100%
  • Neurotensin 78%
  • Small Intestine 54%
  • Calcium 40%
  • Glucose 37%
  27 Citationer (Scopus)

• Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide

  Kuhre, R. E., Wewer Albrechtsen, N. J., Hartmann, B., Deacon, C. F. & Holst, J. J., 1 apr. 2015, I: Journal of Diabetes and its Complications. 29, 3, s. 445-450 6 s.

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  • Gastric Inhibitory Polypeptide 100%
  • Incretins 88%
  • Glucagon-Like Peptide 1 79%
  • Hormones 47%
  • Insulin Secretion 22%
  42 Citationer (Scopus)

• Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine

  Kuhre, R. E., Frost, C. R., Svendsen, B. & Holst, J. J., 1 feb. 2015, I: Diabetes. 64, 2, s. 370-382 13 s.

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  • Glucagon-Like Peptide 1 100%
  • Small Intestine 77%
  • Glucose 53%
  • Sodium-Glucose Transporter 1 52%
  • Phloretin 23%
  93 Citationer (Scopus)

• Stability of glucagon-like peptide-1 and glucagon in human plasma

  Albrechtsen, N. J. W., Bak, M. J., Hartmann, B., Christensen, L. W., Kuhre, R. E., Deacon, C. & Holst, J. J., 16 jan. 2015, I: Endocrine Connections. 4, 1, s. 50-57 8 s.

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  • Glucagon-Like Peptide 1 100%
  • Glucagon 88%
  • Ice 51%
  • Dipeptidyl-Peptidase IV Inhibitors 42%
  • Freezing 21%

• Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine

  Christensen, L. W., Kuhre, R. E., Janus, C., Svendsen, B. & Holst, J. J., 17 sep. 2015, I: Physiological Reports. 3, 9, s. 1-13 13 s., e122551.

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  • Glucagon-Like Peptide 1 100%
  • Small Intestine 77%
  • Blood Vessels 50%
  • 3-cyclopropyl-3-(3-((2-(5,5-dimethylcyclopent-1-en-1-yl)-2'-fluoro-5'-methoxy-(1,1'-biphenyl)-4-yl)methoxy)phenyl)propanoic acid 43%
  • AMG 837 42%
  54 Citationer (Scopus)
• 2014

  Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans

  Kuhre, R. E., Gribble, F. M., Hartmann, B., Reimann, F., Windeløv, J. A., Rehfeld, J. F. & Holst, J. J., 1 apr. 2014, I: American Journal of Physiology: Gastrointestinal and Liver Physiology. 306, 7, s. G622-30 9 s.

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  • Glucagon-Like Peptide 1 100%
  • Fructose 97%
  • Peptides 54%
  • Glucose 53%
  • peptide YY (3-36) 18%
  65 Citationer (Scopus)

• GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines

  Kuhre, R. E., Albrechtsen, N. J. W., Windeløv, J. A., Svendsen, B., Hartmann, B. & Holst, J. J., maj 2014, I: Peptides. 55, s. 52-57 6 s.

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  • Glucagon-Like Peptide 1 100%
  • Intestines 77%
  • Swine 67%
  • Length 50%
  • Cell Line 50%
  35 Citationer (Scopus)

• Glucose Stimulates GLP-1 Secretion from Isolated Perfused Rat Small Intestine by SGLT1 and GLUT2 Mediated Uptake, Causing V-gated Calcium Channel Activation

  Kuhre, R. E., Frost, C. R., Svendsen, B. & Holst, J. J., jun. 2014, I: Diabetes. 63, suppl 1, s. A491 1 s., Abstract no 1915-P.

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  • Glucagon-Like Peptide 1 100%
  • Calcium Channels 91%
  • Small Intestine 77%
  • Glucose 53%
  • Nifedipine 37%

• Incretin secretion: direct mechanisms

  Balk-Møller, E., Holst, J. J. & Kuhre, R. E., 12 jun. 2014, Diapedia: The living textbook of diabetes. European Association for the Study of Diabetes (EASD), s. 1-3 3 s.

  Publikation: Bidrag til bog/antologi/rapport › Encyclopædiartikel › Formidling

  • Incretins 100%
  • Glucagon-Like Peptide 1 90%
  • Peptides 32%
  • Glucose 32%
  • Meals 23%

• Pancreatic effects of GLP-1

  Kuhre, R. E., Albrechtsen, N. J. W. & Holst, J. J., 22 dec. 2014, Diapedia: The Living Textbook of Diabetes. European Association for the Study of Diabetes (EASD)

  Publikation: Bidrag til bog/antologi/rapport › Encyclopædiartikel › Formidling

  • Glucagon-Like Peptide 1 100%
  • Hormones 36%
  • Glucagon 35%
  • Islets of Langerhans 34%
  • Insulin Secretion 33%
  73 Citationer (Scopus)

• Targeting the intestinal L-cell for obesity and type 2 diabetes treatment

  Albrechtsen, N. J. W., Kuhre, R. E., Deacon, C. F. & Holst, J. J., 1 jan. 2014, I: Expert Review of Endocrinology & Metabolism. 9, 1, s. 61-72 12 s.

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  • Enteroendocrine Cells 100%
  • Glucagon-Like Peptide 1 82%
  • Type 2 Diabetes Mellitus 52%
  • Obesity 48%
  • Appetite Regulation 37%
  22 Citationer (Scopus)
• 2011

  Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism

  Petersen, P. S., Jin, C., Madsen, A. N., Rasmussen, M., Kuhre, R., Egerod, K. L., Nielsen, L. B., Schwartz, T. W. & Holst, B., nov. 2011, I: FASEB Journal. s. 3803-3814 12 s., 4.

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  • High Fat Diet 100%
  • Adipocytes 94%
  • Pharmacological Metabolism 77%
  • Food 70%
  • Obesity 69%
  28 Citationer (Scopus)