Niels H. Secher

2019

Dynamic Cerebral Autoregulation Is Maintained during High-Intensity Interval Exercise

Tsukamoto, H., Hashimoto, T., Olesen, N. D., Petersen, L. G., Sørensen, H., Nielsen, H. B., Secher, N. H. & Ogoh, S., 1 Feb 2019, In: Medicine and Science in Sports and Exercise. 51, 2, p. 372-378 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Nasal insulin administration does not affect hepatic glucose production at systemic fasting insulin levels

Plomgaard, P., Hansen, J. S., Ingerslev, B., Clemmesen, J. O., Secher, N. H., van Hall, G., Fritsche, A., Weigert, C., Lehmann, R., Häring, H. U. & Heni, M., 2019, In: Diabetes, Obesity and Metabolism. 21, 4, p. 993-1000

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Protocol for a multicentre retrospective observational cohort study in Denmark: association between the intraoperative peripheral perfusion index and postoperative morbidity and mortality in acute non-cardiac surgical patients

Agerskov, M., Thusholdt, A. N. W., Højlund, J., Meyhoff, C. S., Sørensen, H., Wiberg, S., Secher, N. H. & Bang Foss, N., 1 Nov 2019, In: B M J Open. 9, 11, 6 p., e031249.

Research output: Contribution to journal › Journal article › Research › peer-review

The age-related reduction in cerebral blood flow affects vertebral artery more than internal carotid artery blood flow

Olesen, N. D., Nielsen, H. B., Olsen, N. V. & Secher, N. H., Jul 2019, In: Clinical Physiology and Functional Imaging. 39, 4, p. 255-260

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Time trial performance is sensitive to low-volume autologous blood transfusion

Bejder, J., Andersen, A. B., Solheim, S. A., Gybel-Brask, M., Secher, N. H., Johansson, P. I. & Nordsborg, N. B., 1 Apr 2019, In: Medicine and Science in Sports and Exercise. 51, 4, p. 692-700 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

2018

Absent increase in vertebral artery blood flow during l-arginine infusion in hypertensive men

Vianna, L. C., Fernandes, I. A., Barbosa, T. C., Amaral, T. G., Rocha, N. G., Secher, N. H. & Nóbrega, A. C., 1 Oct 2018, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 315, 4, p. R820-R824 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Administration of platelets to ruptured abdominal aortic aneurysm patients before open surgery: a prospective, single-blinded, randomised study

Lunen, T. B., Johansson, P. I., Jensen, L. P., Homburg, K. M., Roeder, O. C., Lonn, L., Secher, N. H., Helgstrand, U., Carstensen, M., Jensen, K. B., Lange, T., Sillesen, H., Swiatek, F. & Nielsen, H. B., Oct 2018, In: Transfusion Medicine. 28, 5, p. 386-391

Research output: Contribution to journal › Journal article › Research › peer-review

A mesenteric traction syndrome affects near-infrared spectroscopy evaluated cerebral oxygenation because skin blood flow increases

Olesen, N. D., Sørensen, H., Ambrus, R., Svendsen, L. B., Lund, A. & Secher, N. H., 1 Apr 2018, In: Journal of Clinical Monitoring and Computing. 32, 2, p. 261-268

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Elevated arterial lactate delays recovery of intracellular muscle pH after exercise

Volianitis, S., Secher, N. H. & Quistorff, B., Nov 2018, In: European Journal of Applied Physiology. 118, 11, p. 2429-2434

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Elevated Renal Oxygen Extraction During Open Abdominal Aortic Aneurysm Repair Is Related to Postoperative Renal Dysfunction

Olesen, N. D., Jørgensen, T. B., Eiberg, J., Helgstrand, U. J. V., Sillesen, H. H., Cedergreen, P., Secher, N. H. & Nielsen, H. B., 1 Dec 2018, In: Seminars in Cardiothoracic and Vascular Anesthesia. 22, 4, p. 369-375

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Hypoxia compounds exercise-induced free radical formation in humans; partitioning contributions from the cerebral and femoral circulation

Bailey, D. M., Rasmussen, P., Evans, K. A., Bohm, A. M., Zaar, M., Nielsen, H. B., Brassard, P., Nordsborg, N. B., Homann, P. H., Raven, P. B., McEneny, J., Young, I. S., McCord, J. M. & Secher, N. H., 20 Aug 2018, In: Free Radical Biology & Medicine. 124, p. 104-113 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

In response to: phenylephrine and paradoxically increased muscle tissue oxygenation: is the mechanism related to local venoconstriction or augmented venous return?

Sørensen, H., Egesborg, A. H., Thomsen, J. H., Meyer, A. S. P., Terzic, D., Hilsted, L., Kjærgaard, J., Goetze, J. P., Barbosa, T. C. & Secher, N. H., 1 Dec 2018, In: Journal of Clinical Monitoring and Computing. 32, 6, p. 1145-1146

Research output: Contribution to journal › Comment/debate › Research

1 Citation (Scopus)

Maintained exercise-enhanced brain executive function related to cerebral lactate metabolism in men

Hashimoto, T., Tsukamoto, H., Takenaka, S., Olesen, N. D., Petersen, L. G., Sørensen, H., Nielsen, H. B., Secher, N. H. & Ogoh, S., 2018, In: FASEB Journal. 32, 3, p. 1417-1427 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

Matrix Metalloproteinase Mediated Type I Collagen Degradation is an Independent Predictor of Increased Risk of Acute Myocardial Infarction in Postmenopausal Women

Bertelsen, D. M., Neergaard, J. S., Bager, C. L., Nielsen, S. H., Secher, N. H., Svendsen, J. H., Bihlet, A. R., Andersen, J. R., Karsdal, M. A., Christiansen, C. & Nielsen, H. B., 1 Dec 2018, In: Scientific Reports. 8, 7 p., 5371.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

27 Downloads (Pure)

Muscle alpha-adrenergic responsiveness during exercise and ATP-induced vasodilation in chronic obstructive pulmonary disease patients

Iepsen, U. W., Munch, G. W., Ryrso, C. K., Secher, N. H., Lange, P., Thaning, P., Pedersen, B. K. & Mortensen, S. P., Feb 2018, In: American Journal of Physiology: Heart and Circulatory Physiology. 314, 2, p. H180-H187 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Perioperativ væsketerapi har indflydelse på koagulation, blodtab og komplikationer

Translated title of the contribution: Perioperative fluid therapy influences coagulation, blood loss and post-operative complicationsRasmussen, K. C., Pedersen, T. & Secher, N. H., 2018, In: Ugeskrift for Laeger. 180, 21, 4 p., V06170498.

Research output: Contribution to journal › Journal article › Research › peer-review

Phenylephrine increases near-infrared spectroscopy determined muscle oxygenation during head-up tilt in men

Egesborg, A. H., Sørensen, H., Olesen, N. D. & Secher, N. H., 17 Nov 2018, In: Scandinavian Journal of Clinical & Laboratory Investigation. 78, 7-8, p. 601-605

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Pre-operative haemodynamic monitoring and resuscitation in hip fracture patients: Protocol for a prospective observational study

Agerskov, M., Sørensen, H., Højlund, J., Secher, N. H. & Foss, N. B., Oct 2018, In: Acta Anaesthesiologica Scandinavica. 62, 9, p. 1314-1320 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Reduced arterial vasodilatation in response to hypoxia impairs cerebral and peripheral oxygen delivery in hypertensive men

Fernandes, I. A., Rocha, M. P., Campos, M. O., Mattos, J. D., Mansur, D. E., Rocha, H. N. M., Terra, P. A. C., Garcia, V. P., Rocha, N. G., Secher, N. H. & Nóbrega, A. C. L., 1 Apr 2018, In: The Journal of Physiology. 596, 7, p. 1167-1179

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Sodium nitroprusside dilates cerebral vessels and enhances internal carotid artery flow in young men

Olesen, N. D., Fischer, M. & Secher, N. H., 1 Sept 2018, In: Journal of Physiology. 596, 17, p. 3967-3976 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

2017

ACCURACY OF NONINVASIVE ANESTHETIC MONITORING IN THE ANESTHETIZED GIRAFFE (GIRAFFA CAMELOPARDALIS)

Bertelsen, M. F., Grondahl, C., Stegmann, G. F., Sauer, C., Secher, N. H., Hasenkam, J. M., Damkjaer, M., Aalkjaer, C. & Wang, T., 1 Sept 2017, In: Journal of Zoo and Wildlife Medicine. 48, 3, p. 609-615

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP

Ingerslev, B., Hansen, J. S., Hoffmann, C., Clemmesen, J. O., Secher, N. H., Scheler, M., Hrabĕ de Angelis, M., Häring, H. U., Pedersen, B. K., Weigert, C. & Plomgaard, P., Oct 2017, In: Molecular Metabolism. 6, 10, p. 1286-1295 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

47 Downloads (Pure)

A reduced gastric corpus microvascular blood flow during Ivor-Lewis esophagectomy detected by laser speckle contrast imaging technique

Ambrus, R., Svendsen, L. B., Secher, N. H., Rünitz, K., Frederiksen, H.-J., Svendsen, M. B. S., Siemsen, M., Kofoed, S. C. & Achiam, M. P., 3 Apr 2017, In: Scandinavian Journal of Gastroenterology. 52, 4, p. 455-461 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Blood pooling in extrathoracic veins after glossopharyngeal insufflation

Mijacika, T., Frestad, D., Kyhl, K., Barak, O., Drvis, I., Secher, N. H., Buca, A., Obad, A., Dujic, Z. & Madsen, P. L., Apr 2017, In: European Journal of Applied Physiology. 117, 4, p. 641-649 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Carbon monoxide reduces near-infrared spectroscopy determined 'total' hemoglobin: a human volunteer study

Niemann, M. J., Sørensen, H., Siebenmann, C., Lundby, C. & Secher, N. H., 19 May 2017, In: Scandinavian Journal of Clinical and Laboratory Investigation. 77, 4, p. 259-262

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Effect of pulmonary hyperinflation on central blood volume: An MRI study

Mijacika, T., Kyhl, K., Frestad, D., Otto Barak, F., Drvis, I., Secher, N. H., Dujic, Z. & Lav Madsen, P., Sept 2017, In: Respiratory Physiology & Neurobiology. 243, p. 92-96 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Evaluation of Gastric Microcirculation by Laser Speckle Contrast Imaging During Esophagectomy: Presented at the Annual Meeting of the Danish Surgical Society, Copenhagen, Denmark, November 2016.

Ambrus, R., Achiam, M. P., Secher, N. H., Svendsen, M. B. S., Rünitz, K., Siemsen, M. & Svendsen, L. B., 2017, In: Journal of the American College of Surgeons. 225, 3, p. 395-402

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Leg blood flow is impaired during small muscle mass exercise in patients with COPD

Iepsen, U. W., Munch, G. D. W., Rugbjerg, M., Ryrsø, C. K., Secher, N. H., Hellsten, Y., Lange, P., Pedersen, B. K., Thaning, P. & Mortensen, S. P., Sept 2017, In: Journal of Applied Physiology. 123, 3, p. 624-631 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Muscle oxygen saturation increases during head-up tilt-induced (pre)syncope

Lund, A., Sorensen, H., Jensen, T. W., Niemann, M. J., Olesen, N. D., Nielsen, H. B., Olsen, N. V. & Secher, N. H., Sept 2017, In: Acta Physiologica. 221, 1, p. 74-80

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Nitrite and S-Nitrosohemoglobin Exchange Across the Human Cerebral and Femoral Circulation: Relationship to Basal and Exercise Blood Flow Responses to Hypoxia

Bailey, D. M., Peter, R., Overgaard, M., Evans, K. A., Bohm, A. M., Seifert, T., Brassard, P., Zaar, M., Nielsen, H. B., Raven, P. B. & Secher, N. H., 10 Jan 2017, In: Circulation. 135, 2, p. 166-176 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Phenylephrine increases near-infrared spectroscopy determined muscle oxygenation in men

Sørensen, H., Thomsen, J. H., Meyer, A. S. P., Terzic, D., Hilsted, L., Kjærgaard, J., Goetze, J. P., Barbosa, T. C. & Secher, N. H., 1 Dec 2017, In: Journal of Clinical Monitoring and Computing. 31, 6, p. 1159–1166 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Physiological, biochemical, anthropometric, and biomechanical influences on exercise economy in humans

Lundby, C., Montero, D., Gehrig, S., Andersson Hall, U., Kaiser, P., Boushel, R., Meinild Lundby, A.-K., Kirk, N., Valdivieso, P., Flück, M., Secher, N. H., Edin, F., Hein, T. & Madsen, K., Dec 2017, In: Scandinavian Journal of Medicine & Science in Sports. 27, 12, p. 1627-1637

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Plasma pro-atrial natriuretic peptide to estimate fluid balance during open and robot-assisted esophagectomy: a prospective observational study

Strandby, R. B., Ambrus, R., Secher, N. H., Goetze, J. P., Achiam, M. P. & Svendsen, L. B., 3 Feb 2017, In: B M C Anesthesiology. 17, 7 p., 20.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

49 Downloads (Pure)

Postoperative volume balance: does stroke volume increase in Trendelenburg's position?

Frost, H., Mortensen, C. R., Secher, N. H. & Nielsen, H. B., 1 May 2017, In: Clinical Physiology and Functional Imaging. 37, 3, p. 314-316 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Regulation of leg blood flow is impaired during exercise in COPD patients

Iepsen, U. W., Munch, G., Rugbjerg, M., Ryrsø, C., Secher, N. H., Hellsten, Y., Lange, P., Pedersen, B. K., Thaning, P. & Mortensen, S., Sept 2017, In: Acta Anaesthesiologica Scandinavica. 61, 8, p. 1041-1042 2 p., 128.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Severe Postoperative Complications may be Related to Mesenteric Traction Syndrome during Open Esophagectomy

Ambrus, R., Svendsen, L. B., Secher, N. H., Goetze, J. P., Rünitz, K. & Achiam, M. P., Sept 2017, In: Scandinavian Journal of Surgery. 106, 3, p. 241-248 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

The Gly₁₆ allele of the G16R single nucleotide polymorphism in the β2-adrenergic receptor gene augments the glycemic response to adrenaline in humans

Rokamp, K. Z., Staalsø, J. M., Zaar, M., Rasmussen, P., Petersen, L. G., Nielsen, R. V., Secher, N. H., Olsen, N. V. & Nielsen, H. B., Sept 2017, In: Frontiers in Physiology. 8, SEP, 10 p., 661.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

56 Downloads (Pure)

Thermodilution-determined Internal Jugular Venous Flow

Rasmussen, P., Widmer, M., Hilty, M. P., Hug, M., Sørensen, H., Ogoh, S., Sato, K., Secher, N. H., Maggiorini, M. & Lundby, C., 2017, In: Medicine and Science in Sports and Exercise. 49, 4, p. 661-668

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Tympanic membrane temperature decreases during head up tilt: relation to frontal lobe oxygenation and middle cerebral artery mean blood flow velocity

Lorr, D., Lund, A., Fredrikson, M. & Secher, N. H., 17 Nov 2017, In: Scandinavian Journal of Clinical and Laboratory Investigation. 77, 8, p. 587-591

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Whole body hyperthermia, but not skin hyperthermia, accelerates brain and locomotor limb circulatory strain and impairs exercise capacity in humans

Trangmar, S. J., Chiesa, S. T., Kalsi, K. K., Secher, N. H. & González-Alonso, J., 1 Jan 2017, In: Physiological Reports. 5, 2, 17 p., e13108.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

42 Downloads (Pure)

2016

ADRB2 gly16gly Genotype, Cardiac Output, and Cerebral Oxygenation in Patients Undergoing Anesthesia for Abdominal Aortic Aneurysm Surgery

Staalso, J. M., Rokamp, K. Z., Olesen, N. D., Lönn, L. B., Secher, N. H., Olsen, N. V., Mantoni, T., Helgstrand, U. & Nielsen, H. M. B., 1 Dec 2016, In: Anesthesia and Analgesia. 123, 6, p. 1408-1415 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Can a central blood volume deficit be detected by systolic pressure variation during spontaneous breathing?

Dahl, M., Hayes, C., Steen Rasmussen, B., Larsson, A. & Secher, N. H., 11 Aug 2016, In: BMC Anesthesiology. 16, p. 1-8 8 p., 58.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Cardiovascular control during whole body exercise

Volianitis, S. & Secher, N. H., 2016, In: Journal of Applied Physiology. 121, 2, p. 376-390 15 p.

Research output: Contribution to journal › Review › peer-review

16 Citations (Scopus)

Carotid baroreflex function at the onset of cycling in men

Barbosa, T. C., Vianna, L. C., Hashimoto, T., Petersen, L. G., Olesen, N. D., Tsukamoto, H., Sørensen, H., Ogoh, S., Nóbrega, A. C. L. & Secher, N. H., 1 Nov 2016, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 311, 5, p. R870-R878 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Circulating Follistatin Is Liver-Derived and Regulated by the Glucagon-to-Insulin Ratio

Hansen, J. S., Rutti, S., Arous, C., Clemmesen, J. O., Secher, N. H., Drescher, A., Gonelle-Gispert, C., Halban, P. A., Pedersen, B. K., Weigert, C., Bouzakri, K. & Plomgaard, P., Feb 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 2, p. 550-60 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

53 Citations (Scopus)

Coupling between arterial and venous cerebral blood flow during postural change

Ogoh, S., Washio, T., Sasaki, H., Petersen, L. G., Secher, N. H. & Sato, K., 1 Dec 2016, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 311, 6, p. R1255-R1261 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Dynamic cerebral autoregulation is unrelated to decrease in external carotid artery blood flow during acute hypotension in healthy young men

Ogoh, S., Sørensen, H., Hirasawa, A., Sasaki, H., Washio, T., Hashimoto, T., Bailey, D. M. & Secher, N. H., 1 Aug 2016, In: Experimental Physiology. 101, 8, p. 1040-1049 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Effect of endurance versus resistance training on quadriceps muscle dysfunction in COPD: a pilot study

Iepsen, U. W., Munch, G. D. W., Rugbjerg, M., Rinnov, A. R., Zacho, M., Mortensen, S. P., Secher, N. H., Ringbæk, T. J., Pedersen, B. K., Hellsten, Y., Lange, P. & Thaning, P., 27 Oct 2016, In: The International Journal of Chronic Obstructive Pulmonary Disease (Print). 11, p. 2659-2669 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

103 Downloads (Pure)

Effect of perioperative crystalloid or colloid fluid therapy on hemorrhage, coagulation competence, and outcome: A systematic review and stratified meta-analysis

Rasmussen, K. C., Secher, N. H. & Pedersen, T., 2016, In: Medicine (Baltimore). 95, 31, 10 p., e4498.

Research output: Contribution to journal › Review › peer-review

28 Citations (Scopus)

Exogenous L-arginine reduces matrix metalloproteinase-2 and -9 activities and oxidative stress in patients with hypertension

Garcia, V. P., Rocha, H. N. M., Silva, G. M., Amaral, T. A. G., Secher, N. H., Nóbrega, A. C. L., Vianna, L. C. & Rocha, N. G., 15 Jul 2016, In: Life Sciences. 157, p. 125-130 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Niels H. Secher

Research output

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