Martin Willemoës

2019

Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses

Hadrup, N., Knudsen, K. B., Berthing, T., Wolff, H., Bengtson, S., Kofoed, C., Espersen, R., Højgaard, C., Winther, J. R., Willemoës, M., Wedin, I., Nuopponen, M., Alenius, H., Norppa, H., Wallin, H. & Vogel, U., 2019, In: Environmental Toxicology and Pharmacology. 66, p. 116-125 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Steady state kinetic analysis of O-linked GalNAc glycan release catalyzed by endo-α-N-acetylgalactosaminidase

Hansen, D. K., Winther, J. R. & Willemoës, M., 1 Jul 2019, In: Carbohydrate Research. 480, p. 54-60

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

The PCNA interaction motifs revisited: thinking outside the PIP-box

Prestel, A., Wichmann, N., Martins, J. M., Marabini, R., Kassem, N., Broendum, S. S., Otterlei, M., Nielsen, O., Willemoës, M., Ploug, M., Boomsma, W. & Kragelund, B. B., 1 Dec 2019, In: Cellular and Molecular Life Sciences. 76, 24, p. 4923-4943 21 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

2018

A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel

Santner, P., Martins, J. M. D. S., Laursen, J. S., Behrendt, L., Riber, L., Olsen, C. A., Arkin, I. T., Winther, J. R., Willemoës, M. & Lindorff-Larsen, K., 16 Oct 2018, In: Biochemistry. 57, 41, p. 5949-5956

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Nanofibrillated cellulose causes acute pulmonary inflammation that subsides within a month

Ilves, M., Vilske, S., Aimonen, K., Lindberg, H. K., Pesonen, S., Wedin, I., Nuopponen, M., Vanhala, E., Højgaard, C., Winther, J. R., Willemoës, M., Vogel, U., Wolff, H., Norppa, H., Savolainen, K. & Alenius, H., 9 Aug 2018, In: Nanotoxicology. 12, 7, p. 729-746 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Random mutagenesis analysis of the Influenza A M2 proton channel reveals novel resistance mutants

Santner, P., Martins, J. M. D. S., Kampmeyer, C., Hartmann-Petersen, R., Laursen, J. S., Stein, A., Olsen, C. A., Arkin, I. T., Winther, J. R., Willemoës, M. & Lindorff-Larsen, K., 16 Oct 2018, In: Biochemistry. 57, 41, p. 5957-5968

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2017

Eukaryotic transcription factors: paradigms of protein intrinsic disorder

Staby, L., O'Shea, C., Willemoës, M., Theisen, F., Kragelund, B. B. & Skriver, K., 1 Aug 2017, In: Biochemical Journal. 474, 15, p. 2509-2532 24 p.

Research output: Contribution to journal › Review › peer-review

50 Citations (Scopus)

Genotoxic and inflammatory effects of nanofibrillated cellulose in murine lungs

Catalán, J., Rydman, E., Aimonen, K., Hannukainen, K-S., Suhonen, S., Vanhala, E., Moreno, C., Meyer, V., da Silva Perez, D., Sneck, A., Forsström, U., Højgaard, C., Willemoës, M., Winther, J. R., Vogel, U., Wolff, H., Alenius, H., Savolainen, K. M. & Norppa, H., 1 Jan 2017, In: Mutagenesis. 32, 1, p. 23-31 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

Phosphoribosyl diphosphate (PRPP): biosynthesis, enzymology, utilization, and metabolic significance

Hove-Jensen, B., Andersen, K. R., Kilstrup, M., Martinussen, J., Switzer, R. L. & Willemoës, M., 1 Mar 2017, In: Microbiology and Molecular Biology Reviews. 81, 1, 83 p., e00040-16.

Research output: Contribution to journal › Review › peer-review

46 Citations (Scopus)

Positive staining for cellulose in oral pulse granuloma

Virkkunen, S., Wolff, H., Haglund, C., Højgaard, C., Winther, J. R., Willemoës, M., Vogel, U. & Hagström, J., 1 Apr 2017, In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 123, 4, p. 464-467 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Structures and short linear motif of disordered transcription factor regions provide clues to the interactome of the cellular hub radical-induced cell death1

O'Shea, C., Staby, L., Bendsen, S. K., Tidemand, F. G., Redsted, A., Willemoës, M., Kragelund, B. B. & Skriver, K., 13 Jan 2017, In: Journal of Biological Chemistry. 292, 2, p. 512-527 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

2016

A soluble, folded protein without charged amino acid residues

Højgaard, C., Kofoed, C., Espersen, R., Johansson, K. E., Villa, M., Willemoës, M., Lindorff-Larsen, K., Teilum, K. & Winther, J. R., 19 Jul 2016, In: Biochemistry. 55, 28, p. 3949–3956 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

148 Downloads (Pure)

Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template

Johansson, K. E., Johansen, N. T., Christensen, S., Horowitz, S., Bardwell, J. C. A., Olsen, J. G., Willemoës, M., Lindorff-Larsen, K., Ferkinghoff-Borg, J., Hamelryck, T. W. & Winther, J. R., 23 Oct 2016, In: Journal of Molecular Biology. 428, 21, p. 4361-4377 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

80 Downloads (Pure)

2015

Bacillus halodurans strain C125 encodes and synthesizes enzymes from both known pathways to form dUMP directly from Cytosine Deoxyribonucleotides

Oehlenschlæger, C. B., Løvgreen, M. N., Reinauer, E., Lehtinen, E., Pind, M-L. L., Harris, P., Martinussen, J. & Willemoës, M., 2015, In: Applied and Environmental Microbiology. 81, 10, p. 3395-3404 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Mutational analysis of divalent metal ion binding in the active site of class II α-mannosidase from Sulfolobus solfataricus

Hansen, D., Webb, H., Nielsen, J. W., Harris, P., Winther, J. R. & Willemoës, M., 24 Mar 2015, In: Biochemistry. 54, 11, p. 2032-2039 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Protein intrinsic disorder in Arabidopsis NAC transcription factors: transcriptional activation by ANAC013 and ANAC046 and their interactions with RCD1

O'Shea, C., Jensen, M. K., Stender, E. G. P., Kragelund, B. B., Willemoës, M. & Skriver, K., 15 Jan 2015, In: Biochemical Journal. 465, 2, p. 281-294 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

Visualization of nanofibrillar cellulose in biological tissues using a biotinylated carbohydrate binding module of β-1,4-Glycanase

Knudsen, K. B., Kofoed, C., Espersen, R., Højgaard, C., Winther, J. R., Willemoës, M., Wedin, I., Nuopponen, M., Vilske, S., Aimonen, K., Weydahl, I. E. K., Alenius, H., Norppa, H., Wolff, H., Wallin, E. H. R. & Vogel, U., 17 Aug 2015, In: Chemical Research in Toxicology. 28, 8, p. 1627-1635 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

117 Downloads (Pure)

2014

Analysis of surface binding sites (SBSs) in carbohydrate active enzymes with focus on glycoside hydrolase families 13 and 77 - a mini-review

Cockburn, D., Wilkens, C., Ruzanski, C., Andersen, S., Nielsen, J. W., Smith, A. M., Field, R. A., Willemoës, M., Abou Hachem, M. & Svensson, B., Jun 2014, In: Biologia. 69, 6, p. 705-712 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

Catalytic site interactions in yeast OMP synthase

Hansen, M. R., Barr, E. W., Jensen, K. F., Willemoës, M., Grubmeyer, C. & Winther, J. R., 15 Jan 2014, In: Archives of Biochemistry and Biophysics. 542, p. 28-38 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

In Silico prediction of mutant HIV-1 proteases cleaving a target sequence

Jensen, J. H., Willemoës, M., Winther, J. R. & De Vico, L., 5 May 2014, In: P L o S One. 9, 5, 11 p., 5.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

1496 Downloads (Pure)

2012

Degradation of the starch components amylopectin and amylose by barley a-amylase 1: role of surface binding site 2

Nielsen, J. W., Kramhøft, B., Bozonnet, S., Abou Hachem, M., Stipp, S. L. S., Svensson, B. & Willemoës, M., 1 Dec 2012, In: Archives of Biochemistry and Biophysics. 528, 1, p. 1-6 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Metal-ion dependent catalytic properties of Sulfolobus solfataricus class II α-mannosidase

Nielsen, J. W., Poulsen, N. R., Johnsson, A. M. S., Winther, J. R., Stipp, S. L. S. & Willemoës, M., 9 Oct 2012, In: Biochemistry. 51, 40, p. 8039-8046 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Polysaccharide effects on calcite growth: the influence of composition and branching

Nielsen, J. W., Sand, K. K., Pedersen, C. S., Lakshtanov, L. Z., Winther, J. R., Willemoës, M. & Stipp, S. L. S., 3 Oct 2012, In: Crystal Growth & Design. 12, 10, p. 4906-4910 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

2011

Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus

Lauritsen, I. H., Willemoës, M., Jensen, K. F., Johansson, E. & Harris, P., Feb 2011, In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 67, 2, p. 201-208 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

The Biochemical Basis | Nucleotide Metabolism

Martinussen, J., Willemoës, M. & Kilstrup, M., 20 Jan 2011, Comprehensive Biotechnology. . Moo-Young, M., Butler, M., Webb, C., Moreira, A., Grodzinski, B., Cui, Z. F. & Agathos, S. (eds.). 2 ed. Elsevier, Vol. 1. p. 91-107 17 p.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

1 Citation (Scopus)

2010

Accumulation of intermediates of the carbon-phosphorus lyase pathway for phosphonate degradation in phn mutants of Escherichia coli

Hove-Jensen, B., Rosenkrantz, T. J., Zechel, D. L. & Willemoës, M., Jan 2010, In: Journal of Bacteriology. 192, 1, p. 370-374

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

2009

Concerted bifunctionality of the dCTP deaminase-dUTPase from Methanocaldococcus jannaschii: a structural and pre-steady state kinetic analysis

Siggaard, J. H. B., Johansson, E., Vognsen, T. R., Helt, S. S., Harris, P., Larsen, S. & Willemoës, M., 2009, In: Archives of Biochemistry and Biophysics. 490, 1, p. 42-9 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus

Christoffersen, S., Kadziola, A., Johansson, E., Rasmussen, M., Willemoës, M. & Jensen, K. F., 2009, In: Journal of Molecular Biology. 393, 2, p. 464-477

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

2008

Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis

Helt, S. S., Thymark, M., Harris, P., Aagaard, C., Dietrich, J., Larsen, S. & Willemoes, M., 2008, In: Journal of Molecular Biology. 376, 2, p. 554-69 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

Nucleotides, Nucleosides, and Nucleobases

Jensen, K. F., Dandanell, G., Hove-Jensen, B. & Willemoës, M., 2008, EcoSal. Escherichia coli and Salmonella: cellular and molecular biology. Böck, A., Curtis III, R., Kaper, J. B., Karp, P. D., Neidhardt, F. C., Nyström, T., Slauch, J. M. & Squires, C. L. (eds.). Washington, D.C.: ASM International, Vol. Chapter 3.6.2.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

27 Citations (Scopus)

Roles of multiple surface sites, long substrate binding clefts, and carbohydrate binding modules in the action of amylolytic enzymes on polysaccharide substrates

Nielsen, M. M., Seo, E. S., Dilokpimol, A., Andersen, J., Hachem, M. A., Naested, H., Willemoës, M., Bozonnet, S., Kandra, L., Gymnt, G., Haser, R., Aghajari, N. & Svensson, B., 2008, In: Biocatalysis and Biotransformation. 26, 1 & 2, p. 59-67

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

2007

Forskningsbaseret undervisning- og hva' så!

Willemoës, M. & Vogel, U. B., 2007, In: Biozoom. 3

Research output: Contribution to journal › Comment/debate › Research

Mutational analysis of the nucleotide binding site of Escherichia coli dCTP deaminase

Thymark, M., Johansson, E., Larsen, S. & Willemoës, M., 2007, In: Archives of Biochemistry and Biophysics. 470, 1, p. 20-6 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme

Johansson, E., Thymark, M., Bynck, J. H., Fanø, M., Larsen, S. & Willemoës, M., 2007, In: FEBS Journal. 274, 16, p. 4188-4198 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

The pair of sugar tongs site on the non-catalytic domain C of barley a-amylase participates in substrate binding and activity

Bozonnet, S., Jensen, M. T., Nielsen, M. M., Aghajari, N., Jensen, M. H., Kramhøft, B., Willemoës, M., Tanier, S., Haser, R. & Svensson, B., 2007, In: FEBS Journal. 274, p. 5055-5067 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

56 Citations (Scopus)

2006

Interactions between Barley a-Amylases, Substrates, Inhibitors and Regulatory Proteins

Hachem, M. A., Bozonnet, S., Willemoës, M., Bønsager, B. C., Nielsen, M. M., Fukuda, K., Kramhøft, B., Maeda, K., Sigurskjold, B. W., Hägglund, P., Finnie, C., Mori, H., Robert, X., Jensen, M. H., Tranier, S., Aghajari, N., Haser, R. & Svensson, B., 2006, In: Journal of Applied Glycoscience. 53, 2, p. 163-169

Research output: Contribution to journal › Journal article › Research › peer-review

Interactions of barley alpha-amylase isozymes with Ca2+, substrates and proteinaceous inhibitors

Hachem, M. AB., Bozonnet, S., Willemoes, M., Kramhøft, B., Fukuda, K., Bønsager, B. C., Jensen, M. T., Nøhr, J., Tranier, N., Juge, N., Robert, X., Haser, R., Aghajari, N. & Svensson, B., 2006, In: Biocatalysis and Biotransformation. 24, 1-2, p. 83-93

Research output: Contribution to journal › Journal article › Research › peer-review

Niels Bohr – er det ikke noget med nogen antomer? Personer og kanoner i naturvidenskaben.

Vogel, U. B. & Willemoës, M., 2006, In: Biozoom. 1

Research output: Contribution to journal › Comment/debate › Research

Structure of the Sulfolobus solfataricus alpha-glucosidase: Implications for domain conservation and substrate recognition in GH31

Ernst, H. A., Lo Leggio, L., Willemoes, M., Leonard, G. A., Blum, P. & Larsen, S., 2006, In: Journal of Molecular Biology. 358, 4, p. 1106-24

Research output: Contribution to journal › Journal article › Research › peer-review

100 Citations (Scopus)

2005

5 Citations (Scopus)

Lid L11 of the glutamine amidotransferase domain of CTP synthase mediates allosteric GTP activation of glutaminase activity

Willemoës, M., Mølgaard, A., Johansson, E. H. & Martinussen, J., 2005, In: FEBS Journal. 272, 3, p. 856-864 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Når enzymer tøver - CTP - biosyntesen i mælkesyrebakterier

Martinussen, J., Willemoës, M., Kilstrup, M., Jensen, P. R. & Hammer, K., 2005, In: Dansk Kemi. 86, 8, p. 20-22

Research output: Contribution to journal › Comment/debate › Research

Nucleoside triphosphate synthesis catalysed by adenylate kinase is ADP dependent

Willemoes, M. & Kilstrup, M., 2005, In: Archives of Biochemistry and Biophysics. 444, 2, p. 195-199

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes

Johansson, E., Fanø, M., Bynck, J. H., Neuhard, J., Larsen, S., Sigurskjold, B. W., Christensen, U. & Willemoës, M., 2005, In: Journal of Biological Chemistry. 280, 4, p. 3051-9 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

2004

Competition between ammonia derived from internal glutamine hydrolysis and hydroxylamine present in the solution for incorporation into UTP as catalysed by Lactococcus lactis CTP synthase

Willemoes, M., 2004, In: Archives of Biochemistry and Biophysics. 424, p. 105-111

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Sequential dimerization of human zipcode-binding protein IMP1 on RNA: a cooperative mechanism providing RNP stability

Nielsen, J., Kristensen, M. A., Willemoes, M., Nielsen, F. C. & Christiansen, J., 2004, In: Nucleic Acids Research. 32, 14, p. 4368-4376

Research output: Contribution to journal › Journal article › Research › peer-review

71 Citations (Scopus)

Structural, kinetic, and mutational studies of the zinc ion environment in tetrameric cytidine deaminase

Johansson, E., Neuhard, J., Willemoës, M. & Larsen, S., 2004, In: Biochemistry. 43, 20, p. 6020-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetramic Cytidine Deaminase

Johansson, E. H., Neuhard, J., Willemoes, M. & Larsen, S., 2004, In: Biochemistry. 43, p. 6020-6029

Research output: Contribution to journal › Journal article › Research › peer-review

Martin Willemoës

Research output

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