Research output per year
Research output per year
Personal profile
Short presentation
Sine Larsen research is in the areas of structural chemistry and structural biology, where her primary tool is X-ray crystallographic methods.
She was Director of the Centre for Crystallographic Studies 1993-2004 one of the first 23 centres of Danish National Research Foundation.
Sine Larsen was General Secretary and Treasurer of the International Union of X-ray Crystallography (IUCr) 1996-2005, and in 2008 elected president of the IUCr serving on the Executive Committee 2008-2014. (http://scripts.iucr.org/cgi-bin/detailed_display?id=1782)
Since 2003 she has been heavily involved in the large research infrastructures generating X-ray synchrotron radiation and neutrons, as a Director of Research for Life Sciences at ESRF (European Synchrotron Radiation Facility 2003-2009 and as Director of the MAX IV Laboratory 2011-2012.
Presently she serves as a member of the advisory committees of several large facilities.
External positions
1 Sept 1971 → 1 Mar 1974
1 Aug 1970 → 31 Jul 1971
Keywords
- Faculty of Science
- Structural biology
- structural chemistry
- X-ray crystallography
- Neutron Scattering
- Chiral chemistry
- enzyme catalysis
- large X-ray facilities
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A comparative structural analysis of the surface properties of asco-laccases
Ernst, H. A., Jørgensen, L. J., Bukh, C., Piontek, K., Plattner, D. A., Østergaard, L. H., Larsen, S. & Bjerrum, M. J., Nov 2018, In: PLoS ONE. 13, 11, p. 1-27 e0206589.Research output: Contribution to journal › Journal article › Research › peer-review
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A new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model
Skubak, P., Arac, D., Bowler, M. W., Correia, A. R., Hoelz, A., Larsen, S., Leonard, G. A., McCarthy, A. A., McSweeney, S., Mueller-Dieckmann, C., Otten, H., Salzman, G. & Pannu, N. S., 1 Mar 2018, In: I U Cr J. 5, Part 2, p. 166-171 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The nature of ancient Egyptian copper-containing carbon inks is revealed by synchrotron radiation based X-ray microscopy
Christiansen, T., Cotte, M., Loredo-Portales, R., Lindelof, P. E., Mortensen, K., Ryholt, K. & Larsen, S., 1 Dec 2017, In: Scientific Reports. 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystallography is more than crystal structures
Larsen, S., 1 Sept 2015, In: IUCrJ. 2, p. 475-476 2 p.Research output: Contribution to journal › Editorial › peer-review
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The function of the milk-clotting enzymes bovine and camel chymosin studied by a fluorescence resonance energy transfer assay
Jensen, J. L., Jacobsen, J., Moss, M. L., Rasmussen, F., Qvist, K. B., Larsen, S. & van den Brink, J. M., 1 May 2015, In: Journal of Dairy Science. 98, 5, p. 2853-2860 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A new insight into the zinc-dependent DNA-cleavage by the colicin E7 nuclease: a crystallographic and computational study
Czene, A., Tóth, E., Németh, E., Otten, H., Poulsen, J.-C. N., Christensen, H. E. M., Rulíšek, L., Nagata, K., Larsen, S. & Gyurcsik, B., 2014, In: Metallomics. 6, 11, p. 2090-2099 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystallography and large research infrastructures, a perfect marriage
Larsen, S., 29 Aug 2014, In: IUCrJ. 1, Part 5, p. 261-262 2 p.Research output: Contribution to journal › Editorial › peer-review
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Design of thermostable rhamnogalacturonan lyase mutants from Bacillus licheniformis by combination of targeted single point mutations
da Silva, I. I. C. R., Jers, C., Otten, H., Nyffenegger, C., Larsen, D. M., Derkx, P. M. F., Meyer, A. S., Mikkelsen, J. D. & Larsen, S., 2014, In: Applied Microbiology and Biotechnology. 98, 10, p. 4521-4531 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Datasets
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Disentangling thermal motion from disorder in proteins: a low temperature study of perdeuterated HEWL
Joao, R. (Creator), Kay, D. (Creator), Trevor, F. V. (Creator), Michael, H. (Creator), Eva, L. A. (Creator), Larsen, S. (Creator), Helene, L. M. (Creator) & Helen, Y. (Creator), Institut Laue-Langevin (ILL), 2020
DOI: 10.5291/ill-data.8-01-543, https://doi.ill.fr/10.5291/ILL-DATA.8-01-543
Dataset
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X-ray diffraction data of perdeuterated hen egg-white lysozyme at room temperature
Ramos, J. (Creator), Laux, V. (Creator), Mason, S. A. (Creator), Lemee, M. (Creator), Bowler, M. (Creator), Diederichs, K. (Creator), Haertlein, M. (Creator), Forsyth, V. T. (Creator), Mossou, E. (Creator), Larsen, S. (Creator) & Langkilde, A. E. (Creator), Zenodo, 3 Jan 2024
DOI: 10.5281/zenodo.10453790, https://zenodo.org/records/10453790
Dataset
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Neutron diffraction data of hydrogenated hen egg-white lysozyme at room temperature
Ramos, J. (Creator), Laux, V. (Creator), Mason, S. A. (Creator), Lemee, M. (Creator), Bowler, M. (Creator), Diederichs, K. (Creator), Haertlein, M. (Creator), Forsyth, V. T. (Creator), Mossou, E. (Creator), Larsen, S. (Creator) & Langkilde, A. E. (Creator), Zenodo, 3 Jan 2024
DOI: 10.5281/zenodo.10453845, https://zenodo.org/records/10453845
Dataset
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Neutron diffraction data of perdeuterated hen egg-white lysozyme at room temperature
Ramos, J. (Creator), Laux, V. (Creator), Mason, S. A. (Creator), Lemee, M. (Creator), Bowler, M. (Creator), Diederichs, K. (Creator), Haerltein, M. (Creator), Forsyth, V. T. (Creator), Mossou, E. (Creator), Larsen, S. (Creator) & Langkilde, A. E. (Creator), Zenodo, 3 Jan 2024
DOI: 10.5281/zenodo.10453868, https://zenodo.org/records/10453868
Dataset
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Unravelling protein dynamics and the effect of deuteration through neutron sub-atomic single-crystal diffraction data of perdeuterated and p
Joao, R. (Creator), Trevor, F. V. (Creator), Michael, H. (Creator), Eva, L. A. (Creator), Larsen, S. (Creator), Helene, L. M. (Creator), Estelle, M. (Creator) & Helen, Y. (Creator), Institut Laue-Langevin (ILL), 2020
DOI: 10.5291/ill-data.8-01-556, https://doi.ill.fr/10.5291/ILL-DATA.8-01-556
Dataset
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X-ray diffraction data of hydrogenated hen egg-white lysozyme at room temperature
Ramos, J. (Creator), Laux, V. (Creator), Mason, S. A. (Creator), Lemee, M. (Creator), Bowler, M. (Creator), Diederichs, K. (Creator), Haertlein, M. (Creator), Forsyth, V. T. (Creator), Mossou, E. (Creator), Larsen, S. (Creator) & Langkilde, A. E. (Creator), Zenodo, 3 Jan 2024
DOI: 10.5281/zenodo.10453721, https://zenodo.org/records/10453721
Dataset
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Anisotropic displacement parameters of non-hydrogen atoms in proteins from neutron diffraction data measured at multiple temperatures.
Larsen, S. (Creator), Trevor, F. (Creator), Eva, L. A. (Creator), Sax A., M. (Creator) & Estelle, M. (Creator), Institut Laue-Langevin (ILL), 2016
DOI: 10.5291/ill-data.8-01-475, https://doi.ill.fr/10.5291/ILL-DATA.8-01-475
Dataset