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Personal Details

Name: Rasmus Hartmann-Petersen
Born: 1974

Education & Employment

August 2017 -
Professor, Department of Biology, University of Copenhagen, Denmark.

January 2008 - August 2017
Associate Professor, Department of Biology, University of Copenhagen, Denmark.

July 2004 - January 2008
Assistant Professor, Department of Molecular Biology, University of Copenhagen, Denmark.

January 2002 - July 2004
Post Doc at the Human Genetics Unit, MRC, Edinburgh, Scotland.

January 1999 - January 2002
Ph.D. student at the Department of Biochemistry, August Krogh Institute, University of Copenhagen and the Human Genetics Unit, MRC, Edinburgh, Scotland.

June 1998 - January 1999
Research assistant, an industrial diagnostics laboratory, London, England. 

January 1996 - June 1998
M.Sc. student at the Protein Laboratory, Panum Inst., University of Copenhagen, Denmark. 

September 1992 - December 1995
B.Sc. biochemistry student at the University of Copenhagen, Denmark.

Teaching

I teach on the following courses:

Gene technology (lectures, seminars, practicals), Protein Chemistry and Enzymology (lectures, practicals), Protein Science (lectures, seminars).

I supervise students on projects related to:

Protein chemistry, Molecular Biology, Cell Biology & Yeast Genetics.

Knowledge of languages

Danish & English

Fields of interest

Intracellular protein degradation, the 26S proteasome, the ubiquitin system, cellular redox control, protein folding, molecular chaperones.

Current research

Our research activity is primarily centered on intracellular protein degradation via the ubiquitin-proteasome pathway. The ubiquitin-proteasome system is highly conserved and is the major pathway for intracellular proteolysis in all eukaryotic cells. Accordingly, ubiquitin-dependent protein degradation plays a pivotal role in the turnover of key regulatory proteins involved in a series of cellular processes, including cell cycle control, signal transduction, and protein folding. For a number of years a focus area for us has been how abnormal or misfolded proteins are targeted for degradation. To this end, we use fission yeast and mammalian cells in tissue culture as model systems, combined with a series of genetic, biochemical and molecular cell biological methods. In addition, we collaborate closely with a number of other research groups both in Denmark and abroad.

Keywords

  • Faculty of Science
  • Protein Chemistry
  • Molecular Biology
  • Cell Biology
  • Yeast Genetics
  • Protein Degradation
  • Ubiquitin
  • Proteasomes
  • Cellular Protein Quality Control
  • Molecular Chaperones
  • Cellular Redox Regulation
  • Hereditary diseases
  • Protein Misfolding

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