Lona Louring Christrup

Research output

Research output per year 1986 1989 1990 1992 2007 2009 2013 2014 2015 2020

• 152 Journal article
• 12 Poster
• 9 Conference abstract for conference
• 7 Paper
• 15 More
  • 3 Review
  • 3 Other contribution
  • 2 Comment/debate
  • 2 Patent
  • 1 Book
  • 1 Doctoral thesis
  • 1 Book chapter
  • 1 Conference abstract in journal
  • 1 Conference article

Research output per year

Research output per year

Search results

• 1994

  Prolonged release from the injection site of morphine from morphine esters in an oil vehicle given by intramuscular injection to pigs

  Jørgensen, A., Christrup, L. L., Fullerton, A., Christensen, C. B. & Bundgaard, H., Nov 1994, In: Pharmacology & Toxicology. 75, 5, p. 319-20 2 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  7 Citations (Scopus)
• 1993

  Med enkeltbillet til hjernen

  Steffansen, B. & Christrup, L. L., 1993, In: Lægemiddelforskning. p. 28-29 2 p.

  Research output: Contribution to journal › Journal article › Research

• Stereoselective Pharmacokinetics of Methadone in Chronic Pain Patients Measured by HPLC: Abstracts Third International Congress of Therapeutic Drug Monitoring and Clinical Toxicology

  Kristensen, K., Angelo, H. R., Blemmer, T., Christrup, L. L., Drenck, N. E., Sjøgren, P. & Rasmussen, S. N., 1993, 1 p. The Drug Monit.

  Research output: Other contribution › Research
• 1992

  Buccal absorption of ketobemidone and various ester prodrugs in the rat

  Hansen, L. B., Jorgensen, A., Rasmussen, S. N., Christrup, L. L. & Bundgaard, H., 1 Jan 1992, In: International Journal of Pharmaceutics. 88, 1-3, p. 243-250 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prodrug 100%
  • Ketobemidone 100%
  • Buccal Administration 100%
  • Bioavailability 66%
  • Narcotic Analgesics 50%
  6 Citations (Scopus)

• Enhanced delivery of ketobemidone through porcine buccal mucosa in vitro via more lipophilic ester prodrugs

  Hansen, L. B., Christrup, L. L. & Bundgaard, H., 1 Jan 1992, In: International Journal of Pharmaceutics. 88, 1-3, p. 237-242 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lipophilic 100%
  • Porcine Buccal mucosa 100%
  • Ester Prodrug 100%
  • Enhanced Delivery 100%
  • Pig 100%
  16 Citations (Scopus)

• Enhanced transdermal delivery of ketobemidone with prodrugs

  Hansen, L. B., Fullerton, A., Christrup, L. L. & Bundgaard, H., 1 Jan 1992, In: International Journal of Pharmaceutics. 84, 3, p. 253-260 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prodrug 100%
  • Ester Prodrug 100%
  • Transdermal Delivery 100%
  • Ketobemidone 100%
  • Skin Penetration 66%
  5 Citations (Scopus)

• Ketobemidone prodrugs for buccal delivery: Prediction of the extent of saliva-catalyzed hydrolysis of various ester prodrugs under simulated in vivo conditions

  Hansen, L. B., Christrup, L. L. & Bundgaard, H., 1 Jan 1992, In: International Journal of Pharmaceutics. 88, 1-3, p. 229-235 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prodrug 100%
  • In Vivo Conditions 100%
  • Acid Hydrolysis 100%
  • Ester Prodrug 100%
  • Esters 100%
  6 Citations (Scopus)

• Nye lægemiddelformer - smertebehandling af børn

  Rasmussen, M., Christrup, L. L., Rømsing, J., Trøst Jørgensen, J. & Kart, T., 1992, In: Farmaceuten. 4, p. 608-610 3 p.

  Research output: Contribution to journal › Journal article › Research

• Relative bioavailability in man of noscapine administered in lozenges and mixture

  Jensen, L. N., Christrup, L. L., Jacobsen, L., Bonde, J. & Bundgaard, H., 1 Jan 1992, In: Acta Pharmaceutica Nordica. 4, 4, p. 309-312 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Relative Bioavailability 100%
  • Lozenges 100%
  • Noscapine 100%
  • Bioavailability 100%
  • Crossover 100%
  6 Citations (Scopus)

• Saliva-catalyzed hydrolysis of a ketobemidone ester prodrug: Factors influencing human salivary esterase activity

  Hansen, L. B., Christrup, L. L. & Bundgaard, H., 1 Jan 1992, In: International Journal of Pharmaceutics. 88, 1-3, p. 221-227 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Esterase 100%
  • Prodrug 100%
  • Ketobemidone 100%
  • Salivary Esterases 100%
  • Enzymatic Hydrolysis 100%
  7 Citations (Scopus)

• Single-dose and steady-state pharmacokinetics of diltiazem administered in two different tablet formulations

  Christrup, L. L., Bonde, J., Rasmussen, S. N., Sonnergaard, J. M. & Jensen, B. H., Oct 1992, In: Pharmacology & Toxicology. 71, 4, p. 305-7 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Diltiazem 100%
  • Tablet 100%
  • Pharmacokinetic 100%
  • Cmin 33%
  • Steady-state Studies 25%
  3 Citations (Scopus)

• Transport gennem kroppens barrierer

  Bundgaard, H. & Christrup, L. L., 1992, In: Lægemiddelforskning. p. 30-31 2 p.

  Research output: Contribution to journal › Journal article › Research
• 1991

  Chewing gum and lozenges as delivery systems for noscapine

  Norgaard Jensen, L., Christrup, L. L., Menger, N. & Bundgaard, H., 1 Jan 1991, In: Acta Pharmaceutica Nordica. 3, 4, p. 219-222 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lozenges 100%
  • Delivery System 100%
  • Chewing Gum 100%
  • Noscapine 100%
  • Antitussive 33%
  13 Citations (Scopus)

• Deposition of a model substance, 99mTc E-HIDA, in the oral cavity after administration of lozenges, chewing gum and sublingual tablets

  Christrup, L. L., Davis, S., Frier, M., Melia, C., Rasmussen, S. N., Washington, N., Wilding, I. & Andersen, C., 1991. 1 p.

  Research output: Contribution to conference › Paper › Research

• Evaluation of the transdermal route for administration of narcotic analgesics: Human skin permeability studies of methadone and pethidine

  Fullerton, A., Christrup, L. L. & Bundgaard, H., 1 Jan 1991, In: Acta Pharmaceutica Nordica. 3, 3, p. 181-182 2 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  4 Citations (Scopus)

• Ketobemidone prodrugs for buccal delivery

  Bach Hansen, L., Christrup, L. L. & Bundgaard, H., 1 Jan 1991, In: Acta Pharmaceutica Nordica. 3, 2, p. 77-82 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  9 Citations (Scopus)

• Prodrugs of morphine for transdermal delivery

  Fullerton, A., Drustrup, J., Bundgaard, H. & Christrup, L. L., 1991. 6 p.

  Research output: Contribution to conference › Paper › Research

• Transdermal delivery of the narcotic analgesic ketobemidone and some ketobemidone prodrugs through human skin

  Hansen, L. B., Fullerton, A., Christrup, L. L. & Bundgaard, H., 1991. 1 p.

  Research output: Contribution to conference › Paper › Research › peer-review

• Tyggegummi til stofmisbrugere : det er vigtigt at finde nye veje til at begrænse spredningen af HIV-smitte

  Kristensen, F., Christrup, L., Angelo, H. R., Achen, P. & Jepsen, P. W., 1991, In: Farmaci. 12, p. 366-367 2 p.

  Research output: Contribution to journal › Journal article › Research

• Utilization of prodrugs to enhance the transdermal absorption of morphine

  Drustrup, J., Fullerton, A., Christrup, L. L. & Bundgaard, H., 1 Jan 1991, In: International Journal of Pharmaceutics. 71, 1-2, p. 105-116 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prodrug 100%
  • Morphine 100%
  • Transdermal 100%
  • Esters 33%
  • Skin Penetration 22%
  26 Citations (Scopus)
• 1990

  Deposition of a model substance, Tc E-HIDA, in the oral cavity after administration of lozenges, chewing gum and sublingual tablets

  Christrup, L. L., Davis, S. S., Melia, C. D., Wilding, I. R., Frier, M., Rasmussen, S. N., Washington, N. & Andersen, C., 1 Dec 1990, In: International Journal of Pharmaceutics. 66, 1-3, p. 169-174 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lozenges 100%
  • Sublingual Tablets 100%
  • Oral Cavity 100%
  • Chewing Gum 100%
  • Masticatory Force 100%
  14 Citations (Scopus)

• In vivo og in vitro henfaldstider af Dumozolam resoribletter og Halcion tabletter

  Christrup, L. L., Bonde, J., Møller-Sonnergaard, J. & Vestergaard, O., 1990, In: Farmaceuten. 2, p. 788-791 4 p.

  Research output: Contribution to journal › Journal article › Research

• Ketobemidone prodrugs

  Bundgaard, H. (Inventor), Christrup, L. L. (Inventor), Fullerton, A. (Inventor) & Hansen, L. B. (Inventor), 1990

  Research output: Patent

• Ketobemidon prodrug til sublingual/buccal og transdermal administration

  Hansen, L. B., Christrup, L. L., Rasmussen, S. N. & Bundgaard, H., 1990, In: Danmarks Farmaceutiske Højskoles årsberetning 1990-1991. p. 29-31 3 p.

  Research output: Contribution to journal › Journal article › Research

• Langtidsvirkende opioider--begraensninger og fordele

  Translated title of the contribution: Delayed-action opioids--limitations and advantagesBonde, J., Christrup, L. L. & Jonsson, T., 2 Apr 1990, In: Ugeskrift for Laeger. 152, 14, p. 1022-4 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Pethidine is unsuitable for buccal administration

  Christrup, L. L., Bonde, J., Wulff, M. B., Armandi, H. B. & Flachs, H., Apr 1990, In: Pharmacology & Toxicology. 66, 4, p. 315-6 2 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  1 Citation (Scopus)

• Relative bioavailability of (±)-verapamil hydrochloride administered in tablets and chewing gum

  Christrup, L. L., Bonde, J., Rasmussen, S. N. & Rassing, M. R., 1 Jan 1990, In: Acta Pharmaceutica Nordica. 2, 6, p. 371-376 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  20 Citations (Scopus)

• Relative bioavailability of methadone hydrochloride administered in chewing gum and tablets

  Christrup, L. L., Angelo, H. R., Bonde, J., Kristensen, F. & Rasmussen, S. N., 1 Jan 1990, In: Acta Pharmaceutica Nordica. 2, 2, p. 83-88 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Methadone 100%
  • Tablet 100%
  • Bioavailability 100%
  • Methadone Hydrochloride 100%
  • Chewable Tablets 100%
  11 Citations (Scopus)

• Use of methadone chewing gum in the treatment of narcotic addicts

  Christrup, L. L., Aachen, F., Angelo, H. R., Bonde, J., Kristensen, F. & Rasmussen, S. N., 1990. 2 p.

  Research output: Contribution to conference › Paper › Research › peer-review
• 1989

  Behandling af kroniske smerter

  Andersen, S., Bonde, J. & Christrup, L. L., 1989, In: Farmaci. 7, p. 207-209 3 p.

  Research output: Contribution to journal › Journal article › Research

• Det gør ondt

  Andersen, S., Bonde, J. & Christrup, L. L., 1989, In: Farmaci. 1, p. 16 1 p.

  Research output: Contribution to journal › Journal article › Research

• Konference om klinisk farmakologi/terapi

  Angelo, H. R., Christrup, L. L. & Flachs, H., 1989, In: Farmaceuten. 22, p. 804-805 2 p.

  Research output: Contribution to journal › Journal article › Research

• Kroniske smerter

  Andersen, S., Bonde, J. & Christrup, L. L., 1989, In: Farmaci. 6, p. 171 1 p.

  Research output: Contribution to journal › Journal article › Research

• Medicinsk behandling af akutte smerter

  Andersen, S., Bonde, J. & Christrup, L. L., 1989, In: Farmaci. 5, p. 147 1 p.

  Research output: Contribution to journal › Journal article › Research

• Opiater og beslægtede syntetiske stoffer

  Andersen, S., Bonde, J. & Christrup, L. L., 1989, In: Farmaci. 3, p. 84-85 2 p.

  Research output: Contribution to journal › Journal article › Research

• Sådan indgives smertestillende midler

  Andersen, S., Bonde, J. & Christrup, L. L., 1989, In: Farmaci. 2, p. 45 1 p.

  Research output: Contribution to journal › Journal article › Research

• Smerteklinikker

  Johansen, S. H., Christrup, L. L., Andersen, S. & Bonde, J., 1989, In: Farmaci. 10, p. 297 1 p.

  Research output: Contribution to journal › Journal article › Research

• Smerter ved cancer

  Andersen, S., Bonde, J. & Christrup, L. L., 1989, In: Farmaci. 8, p. 235 1 p.

  Research output: Contribution to journal › Journal article › Research
• 1988

  Chewing gum as a drug delivery system II: Influence of formulation upon the release rate of salicylamide

  Christrup, L. L. & Rassing, M. R., 1988, In: Farmaci Sci Ed. 16, p. 1-5 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Chewing gum as a drug delivery system III: Bioavailability of salicylamid administered in tablets and chewing gum

  Christrup, L. L., Bonde, J., Eriksen, H., Rasmussen, S. N., Rassing, M. R. & Simonsen, K., 1988, In: Farmaci Sci Ed. 16

  Research output: Contribution to journal › Journal article › Research › peer-review

• Chewing gum as a drug delivery system IV: Excretion of ascorbic acid in urine after administration in chewing tablets and chewing gum

  Christrup, L. L., Rasmussen, S. N. & Rassing, M. R., 1988, In: Farmaci Sci Ed. 16, p. 44-47 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
• 1987

  Absorption of progesterone through the oral mucosa

  Rassing, M. R., Christrup, L. L. & Sonnergaard, J., 1987. 1 p.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

• Bioavailability of salicylamide after administration of tablets and chewing gum formulations

  Christrup, L. L., Bonde, J., Eriksen, H., Rasmussen, S. N., Rassing, M. R. & Simonsen, K., 1987. 7 p.

  Research output: Contribution to conference › Paper › Research
• 1986

  Chewing gum as a drug delivery system I: In vitro simulation of human mastication and influence of formulation upon release of a water soluble drug

  Christrup, L. L. & Møller, N., 1986, In: Arch Pharm Chem Sci Ed. 14, p. 30-36 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• The oral cavity as application site for drugs - Biopharmaceutical aspects on chewing gum as drug delivery systems

  Christrup, L. L., 1986, Copenhagen, Denmark: Royal Danish School of Pharmacy.

  Research output: Book/Report › Doctoral thesis