José Moreira

Research output

Research output per year 1998 2005 2006 2008 2010 2013 2014 2015 2018 2019 2019

• 53 Journal article
• 6 Review
• 4 Editorial
• 1 Book chapter
• 1 More
  • 1 Conference abstract in journal

Research output per year

Research output per year

Search results

• 2019

  Allosteric regulation of AMP-activated protein kinase by adenylate nucleotides and small-molecule drugs

  Matos, A. L. D. S. A., Oakhill, J. S., Moreira, J., Loh, K., Galic, S. & Scott, J. W., 30 Apr 2019, In: Biochemical Society Transactions. 47, p. 733-741

  Research output: Contribution to journal › Review › peer-review

  • Allosteric Regulation 100%
  • Adenosine Monophosphate 75%
  • Adenosine 64%
  • Protein Kinases 62%
  • Nucleotide 55%
  6 Citations (Scopus)

• Metallopeptidase Inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer

  Nordgaard, C., Doll, S., Matos, A. L. D. S. A., Høeberg, M., Kazi, J. U., Friis, S., Stenvang, J., Rönnstrand, L., Mann, M. & Moreira, J. M. A., 1 Dec 2019, In: Molecular Oncology. 13, 12, p. 2646-2662

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tissue Inhibitor of Metalloproteinase-1 100%
  • Receptor Protein-Tyrosine Kinases 89%
  • Metalloproteases 89%
  • Colorectal Neoplasms 66%
  • Alleles 11%
  2 Citations (Scopus)

  16 Downloads (Pure)

• Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer

  Flores-Morales, A., Bergmann, T. B., Lavallee, C., Batth, T. S., Lin, D., Lerdrup, M., Friis, S., Bartels, A., Kristensen, G., Krzyzanowska, A., Xue, H., Fazli, L., Hansen, K., Røder, M. A., Brasso, K., Moreira, J. M., Bjartell, A., Wang, Y., Olsen, J. V., Collins, C. C., & 1 othersIglesias-Gato, D., 15 Jan 2019, In: Clinical Cancer Research. 25, 2, p. 1-15

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Proteogenomics 100%
  • Castration 66%
  • Heterografts 53%
  • Prostatic Neoplasms 47%
  • Proteome 9%
  21 Citations (Scopus)

• Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion

  Brix, D. M., Tvingsholm, S. A., Hansen, M. B., Clemmensen, K. B., Ohman, T., Siino, V., Lambrughi, M., Hansen, K., Puustinen, P., Gromova, I., James, P., Papaleo, E., Varjosalo, M., Moreira, J., Jäättelä, M. & Kallunki, T., 25 Apr 2019, In: Oncogene. 38, p. 3170-3184

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Zinc Fingers 100%
  • Lysosomes 90%
  • Serine 85%
  • Phosphorylation 60%
  • Breast Neoplasms 21%
  9 Citations (Scopus)
• 2018

  Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas

  Aaberg-Jessen, C., Sørensen, M. D., Matos, A. L. S. A., Moreira, J. M., Brünner, N., Møldrup Knudsen, A. & Kristensen, B. W., 9 Mar 2018, In: BMC Cancer. 18, 16 p., 270.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tissue Inhibitor of Metalloproteinase-1 100%
  • Glioblastoma 82%
  • Astrocytoma 20%
  • Calcium 9%
  • Fluorescent Antibody Technique 7%
  10 Citations (Scopus)

  23 Downloads (Pure)

• Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1

  Tvingsholm, S. A., Hansen, M. B., Clemmensen, K. K. B., Brix, D. M., Rafn, B., Frankel, L. B., Louhimo, R., Moreira, J., Hautaniemi, S., Gromova, I., Jäättelä, M. & Kallunki, T., 2018, In: Oncogene. 7, 2, p. 1-15 15 p., 14.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Zinc Fingers 100%
  • Zinc 84%
  • MicroRNAs 74%
  • Transcription Factors 66%
  • Lysosomes 50%
  14 Citations (Scopus)

  42 Downloads (Pure)

• Predictive value of combined analysis of pro-NPY and ERG in localized prostate cancer

  Kristensen, G., Røder, M. A., Berg, K. D., Elversang, J., Iglesias-Gato, D., Moreira, J., Toft, B. G. & Brasso, K., Oct 2018, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 126, 10, p. 804-813

  Research output: Contribution to journal › Journal article › Research › peer-review

  • proneuropeptide Y 100%
  • Prostatic Neoplasms 40%
  • Castration 37%
  • Prostatectomy 13%
  • Regression Analysis 5%
  7 Citations (Scopus)

• The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms

  Andersen, A. P., Samsøe-Petersen, J., Ørnbo, E. K., Bødtkjer, E., Moreira, J., Kveiborg, M. & Pedersen, S. H. F., 15 Jun 2018, In: International Journal of Cancer. 142, 12, p. 2529-2542 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • transporter 100%
  • tumors 83%
  • cancer 82%
  • acids 78%
  • Acids 66%
  31 Citations (Scopus)
• 2017

  Elucidation of Altered Pathways in Tumor-Initiating Cells of Triple-Negative Breast Cancer: A Useful Cell Model System for Drug Screening

  Christensen, A. G., Ehmsen, S., Terp, M. G., Batra, R., Alcaraz, N., Baumbach, J., Noer, J. B., Moreira, J., Leth-Larsen, R., Larsen, M. R. & Ditzel, H. J., Aug 2017, In: Stem Cells. 35, 8, p. 1898-1912

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Triple Negative Breast Neoplasms 100%
  • Preclinical Drug Evaluations 98%
  • Neoplastic Stem Cells 88%
  • Neoplasms 26%
  • Catenins 17%
  7 Citations (Scopus)

• Identification of BLCAP as a novel STAT3 interaction partner in bladder cancer

  Gromova, I., Svensson, S., Gromov, P. & Moreira, J. M. A., Nov 2017, In: PloS one. 12, 11, 18 p., e0188827.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • urinary bladder neoplasms 100%
  • Bladder Cancer 99%
  • Protein 68%
  • Urinary Bladder Neoplasms 62%
  • cancer 61%
  2 Citations (Scopus)

• Molecular Oncology journal has moved to open access

  Celis, J. E. & Moreira, J., 1 Feb 2017, In: Molecular Oncology. 11, 2, 1 p.

  Research output: Contribution to journal › Editorial › peer-review
• 2016

  Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines

  Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N., & 2 othersRasmussen, A-S. S. & Stenvang, J., 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Irinotecan 100%
  • Breast Neoplasms 54%
  • Cell Line 50%
  • NSC 724998 36%
  • ATP Binding Cassette Transporter, Subfamily G, Member 2 13%
  24 Citations (Scopus)

• The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells

  Hansen, S. N., Ehlers, N. S., Zhu, S., Thomsen, M. B. H., Nielsen, R. L., Liu, D., Wang, G., Hou, Y., Zhang, X., Xu, X., Bolund, L., Yang, H., Wang, J., Moreira, J., Ditzel, H. J., Brünner, N., Rasmussen, A-S. S., Stenvang, J. & Gupta, R., 9 Jun 2016, In: B M C Genomics. 17, 15 p., 442.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Exome 100%
  • Docetaxel 93%
  • Breast Neoplasms 53%
  • MCF-7 Cells 26%
  • taxane 21%
  14 Citations (Scopus)

  125 Downloads (Pure)

• TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: A potential novel approach to the treatment of metastatic colorectal cancer

  Tarpgaard, L. S., Ørum-Madsen, M. S., Christensen, I. J., Nordgaard, C., Noer, J., Guren, T. K., Glimelius, B., Sorbye, H., Ikdahl, T., Kure, E. H., Tveit, K. M., phw435, P., Pfeiffer, P., Brünner, N. & Moreira, J., 8 Aug 2016, In: OncoTarget. 7, 37, p. 59441-59457 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tissue Inhibitor of Metalloproteinase-1 100%
  • Epidermal Growth Factor 81%
  • Colorectal Neoplasms 66%
  • Phenotype 50%
  • ErbB Receptors 45%
  5 Citations (Scopus)
• 2015

  Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

  Hansen, S. N., Westergaard, D., Thomsen, M. B. H., Vistesen, M. V., Do, K. N., Fogh, L., Belling, K. G., Wang, J., Yang, H., Gupta, R., Ditzel, H. J., Moreira, J., Brünner, N., Stenvang, J. & Rasmussen, A-S. S., 11 Jun 2015, In: Tumor Biology. 36, 6, p. 4327-4338 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Docetaxel 100%
  • Up-Regulation 64%
  • Breast Neoplasms 57%
  • Glycoproteins 45%
  • Permeability 38%
  25 Citations (Scopus)

• Drug transporters in breast cancer: response to anthracyclines and taxanes

  Kümler, I., Stenvang, J., Moreira, J., Brünner, N. & Nielsen, D. L., 2 Sept 2015, In: Expert Review of Anticancer Therapy. 15, 9, p. 1075-1092 18 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Taxoids 100%
  • Anthracyclines 87%
  • Breast Neoplasms 49%
  • Pharmaceutical Preparations 31%
  • ATP-Binding Cassette Transporters 30%
  4 Citations (Scopus)

• Establishment and characterization of models of chemotherapy resistance in colorectal cancer: towards a predictive signature of chemoresistance

  Jensen, N. F., Stenvang, J., Beck, M. K., Hanáková, B., Belling, K. C., Do, K. N., Viuff, B. M., Nygård, S. B., Gupta, R., Rasmussen, M. H., Tarpgaard, L. S., Hansen, T. P., Budinská, E., Pfeiffer, P., Bosman, F., Tejpar, S., Roth, A., Delorenzi, M., Andersen, C. L., Rømer, M. U. K., & 2 othersBrünner, N. & Moreira, J., 1 Jun 2015, In: Molecular Oncology. 9, 6, p. 1169-1185 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Colorectal Neoplasms 100%
  • Oxaliplatin 89%
  • Irinotecan 88%
  • Cell Line 74%
  • Drug Therapy 74%
  42 Citations (Scopus)

• High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy

  Gromova, I., Gromov, P., Honma, N., Kumar, S., Rimm, D., Talman, M-L. M., Wielenga, V. T. & Moreira, J., 1 Oct 2015, In: Molecular Oncology. 9, 8, p. 1636-1654 19 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Phosphoglycerate Dehydrogenase 100%
  • Keratin-5 83%
  • Cell Lineage 59%
  • Breast 43%
  • Triple Negative Breast Neoplasms 30%
  24 Citations (Scopus)

• Identification and characterization of a new TIMP-1 binding protein

  Moreira, J., Høeberg, M., Lademann, U. A., Viuff, B. M., Jensen, L. V., Stenvang, J., Nygård, S. B., Ørum-Madsen, M. S., Vistesen, M. V., Fuglsang, A. T., Liu, S. & Brünner, N., 2015, In: Cancer Research. 75, 9 suppl., 1 p., Abstract P5-07-08.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• Intact and cleaved plasma soluble urokinase receptor in patients with metastatic colorectal cancer treated with oxaliplatin with or without cetuximab

  Tarpgaard, L. S., Christensen, I. J., Høyer-Hansen, G., Lund, I. K., Guren, T. K., Glimelius, B., Sorbye, H., Tveit, K. M., Nielsen, H. J., Moreira, J., Pfeiffer, P. & Brünner, N., 15 Nov 2015, In: International Journal of Cancer. 137, 10, p. 2470-7 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Urokinase Plasminogen Activator Receptors 100%
  • Cetuximab 89%
  • Oxaliplatin 84%
  • Urokinase-Type Plasminogen Activator 81%
  • cancer 67%
  6 Citations (Scopus)

• Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer

  Kümler, I., Balslev, E., Poulsen, T. S., Nielsen, S. L., Nygård, S. B., Rømer, M. U., Christensen, I. J., Høgdall, E., Moreira, J., Nielsen, D. L., Brünner, N. & Stenvang, J., 15 Oct 2015, In: International Journal of Cancer. 137, 8, p. 2000-2006 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • genes 100%
  • breast 90%
  • cancer 80%
  • aberration 75%
  • Breast Neoplasms 54%
  10 Citations (Scopus)
• 2014

  CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation: CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

  Puustinen, P., Rytter, A., Mortensen, M., Kohonen, P., Moreira, J. & Jäättelä, M., 2014, In: Journal of Cell Biology. 204, 5, p. 713-727 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  49 Citations (Scopus)

• Comparative analysis of evolutionarily conserved motifs of epidermal growth factor receptor 2 (HER2) predicts novel potential therapeutic epitopes

  Deng, X., Zheng, X., Yang, H., Moreira, J., Brünner, N. & Christensen, H., 5 Sept 2014, In: PLOS ONE. 9, 9, 9 p., e106448.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • erbB-2 receptor 100%
  • Epidermal Growth Factor 89%
  • Human Factors 86%
  • Epitopes 83%
  • Growth Factors 72%
  3 Citations (Scopus)

  802 Downloads (Pure)

• FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast

  Gromov, P., Espinoza, J. A., Talman, M-L., Honma, N., Kroman, N., Wielenga, V. T., Moreira, J. & Gromova, I., 12 Nov 2014, In: P L o S One. 9, 11, 14 p., e112024.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Estrogens 100%
  • Androgens 76%
  • Receptor 75%
  • Estrogen Receptor 69%
  • breast neoplasms 67%
  16 Citations (Scopus)

  358 Downloads (Pure)

• Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment

  Andersen, A. P., Moreira, J. & Pedersen, S. H. F., 19 Mar 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tumor Microenvironment 100%
  • Ion Channels 95%
  • neoplasm cells 87%
  • transporters 83%
  • Pharmacological Metabolism 74%
  61 Citations (Scopus)

• Looking back, to go forward

  Moreira, J. M. A., 1 Jan 2014, In: Molecular Oncology. 8, 3, p. 445-446 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Proteomic analysis of tissue samples in translational breast cancer research

  Gromov, P., Moreira, J. & Gromova, I., Jun 2014, In: Expert Review of Proteomics. 11, 3, p. 285-302 18 p.

  Research output: Contribution to journal › Review › peer-review

  • Proteomics 100%
  • Breast Neoplasms 69%
  • Biological Marker 49%
  • Technology 47%
  • Protein 44%
  11 Citations (Scopus)

• Purification and characterization of bioactive his₆-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells

  Jensen, L. V., Lademann, U. A., Andersen, E. V., Højrup, P., Thaysen-Andersen, M., Krogh, B. O., Viuff, B. M., Brünner, N., Stenvang, J. & Moreira, J., Sept 2014, In: Protein Expression and Purification. 101, p. 157-164 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • human TIMP1 protein 100%
  • Tissue Inhibitor of Metalloproteinase-1 65%
  • Glycosylation 22%
  • Proteins 20%
  • His-His-His-His-His-His 15%
  5 Citations (Scopus)
• 2013

  Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development

  Stenvang, J., Kümler, I., Nygård, S. B., Smith, D. H., Nielsen, D., Brünner, N. & Moreira, J., 2013, In: Frontiers in Oncology. 3, 9 p., 313.

  Research output: Contribution to journal › Review › peer-review

  • Drug Development 100%
  • Biomarkers 68%
  • Drug Therapy 62%
  • Drug Repositioning 48%
  • Neoplasms 34%
  28 Citations (Scopus)

• Contribution of Na⁺,HCO₃^--cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7)

  Bødtkjer, E., Moreira, J., Mele, M., Vahl, P., Wielenga, V. T., Christiansen, P. M., Jensen, V. E. D., Pedersen, S. H. F. & Aalkjær, C., 15 Mar 2013, In: International Journal of Cancer. 132, 6, p. 1288-1299 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • loci 100%
  • breast 93%
  • cancer 83%
  • magnetic permeability 64%
  • Breast Neoplasms 56%
  73 Citations (Scopus)

• Proteomic profiling of triple-negative breast carcinomas in combination with a three-tier orthogonal technology approach identifies Mage-A4 as potential therapeutic target in estrogen receptor negative breast cancer

  Cabezón, T., Gromova, I., Gromov, P., Serizawa, R. R., Wielenga, V. T., Kroman, N. T., Celis, J. E. & Moreira, J., Feb 2013, In: Molecular & Cellular Proteomics. 12, 2, p. 381-394 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Estrogen 100%
  • Triple Negative Breast Neoplasms 93%
  • Estrogen Receptors 87%
  • Proteomics 85%
  • human ERBB2 protein 76%
  32 Citations (Scopus)

• Proximity probing assays for simultaneous visualization of protein complexes in situ

  Moreira, J., Thorsen, S. B., Brünner, N. & Stenvang, J., Jun 2013, In: Expert Review of Proteomics. 10, 3, p. 219-221 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Protein 100%
  • Proteins 89%
  • Biological Marker 54%
  • Biomarkers 45%
  • Biological Role 37%
  6 Citations (Scopus)

• TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells

  Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A-S., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, J., Jensen, L. J., Gupta, R., Lademann, U. A., Brünner, N., Olsen, J. V., & 1 othersStenvang, J., 6 Sept 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tissue Inhibitor of Metalloproteinase-1 100%
  • Drug Resistance 76%
  • Phosphorylation 57%
  • Breast Neoplasms 53%
  • Topoisomerase Inhibitor 46%
  24 Citations (Scopus)

• Tumor interstitial fluid: a treasure trove of cancer biomarkers

  Gromov, P., Gromova, I., Olsen, C. J., Timmermans-Wielenga, V., Talman, M-L., Serizawa, R. R. & Moreira, J., 2013, In: B B A - Proteins and Proteomics. 1834, 11, p. 2259-2270 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Extracellular Fluid 100%
  • Interstitial 92%
  • Tumor Biomarkers 86%
  • Biological Marker 79%
  • Neoplasms 28%
  51 Citations (Scopus)
• 2012

  ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression

  Rafn, B., Nielsen, C. F., Andersen, S. H., Szyniarowski, P., Corcelle-Termeau, E., Valo, E., Fehrenbacher, N., Olsen, C. J., Daugaard, M., Egebjerg, C., Bøttzauw, T., Kohonen, P., Nylandsted, J., Hautaniemi, S., Moreira, J. M. A., Jaattela, M. & Kallunki, T., 30 Mar 2012, In: Molecular Cell. 45, 6, p. 764-776 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cathepsin B 100%
  • Zinc Fingers 86%
  • Breast Neoplasms 49%
  • Cysteine 36%
  • Protein Kinases 35%
  83 Citations (Scopus)

• Immunoexpression analysis and prognostic value of BLCAP in breast cancer

  Gromova, I., Gromov, P., Kroman, N., Wielenga, V. T., Simon, R., Sauter, G. & Moreira, J., 25 Sept 2012, In: P L o S One. 7, 9, 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Breast Cancer 100%
  • breast neoplasms 92%
  • cancer 75%
  • Tissue 68%
  • Bladder Cancer 61%
  6 Citations (Scopus)
• 2010

  Bladder cancer-associated protein, a potential prognostic biomarker in human bladder cancer

  Moreira, J. M. A., Ohlsson, G., Gromov, P., Simon, R., Sauter, G., Celis, J. E. & Gromova, I., Jan 2010, In: Molecular & Cellular Proteomics. 9, 1, p. 161-77 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Urinary Bladder Neoplasms 100%
  • Biological Marker 94%
  • Biomarkers 67%
  • Protein 43%
  • Proteins 38%
  37 Citations (Scopus)

• Challenges and Opportunities in Oncoproteomics

  Celis, J. E. & Moreira, J. M. A., 1 Jan 2010, In: Molecular Oncology. 4, 6, p. 459-460 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts.

  Olsen, C. J., Moreira, J., Lukanidin, E. M. & Ambartsumian, N. S., 1 Jan 2010, In: BMC Cancer. 10, 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Heterografts 100%
  • Breast 84%
  • Fibroblasts 82%
  • Breast Neoplasms 71%
  • Neoplasms 35%
  65 Citations (Scopus)

• Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy

  Moreira, J. M. A., Cabezón, T., Gromova, I., Gromov, P., Timmermans, V. J. M., Machado, I., Llombart-Bosch, A., Kroman, N. T., Rank, F. & Celis, J. E., Dec 2010, In: Molecular Oncology. 4, 6, p. 539-561 23 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Human Mammary Glands 100%
  • Proteomics 83%
  • Breast 69%
  • Phenotype 54%
  • Keratin-15 47%
  18 Citations (Scopus)
• 2009

  Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort

  Celis, J. E., Cabezon, T., Moreira, J., Gromov, P., Gromova, I., Timmermans-Wielenga, V., Iwase, T., Akiyama, F., Honma, N. & Rank, F., 2009, In: Molecular Oncology. 3, 3, p. 220-37

  Research output: Contribution to journal › Journal article › Research › peer-review

  36 Citations (Scopus)
• 2008

  A combined proteome and ultrastructural localization analysis of 14-3-3 proteins in transformed human amnion (AMA) cells

  Shen, T., Ohlsson, G., Gromov, P., Gromova, I., Celis, J. E. & Moreira, J., 1 Jul 2008, In: Molecular and Cellular Proteomics. 7, 7, p. 1225-1240 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • 14-3-3 Proteins 100%
  • Amnion 87%
  • Proteome 75%
  • Protein Isoforms 58%
  • Protein 29%
  20 Citations (Scopus)

• A single lysis solution for the analysis of tissue samples by different proteomic technologies

  Gromov, P., Celis, J. E., Gromova, I., Rank, F., Timmermans, V. J. M. & Moreira, J., 2008, In: Molecular Oncology. 2, 4, p. 368-379 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Proteomics 100%
  • Technology 71%
  • Buffers 60%
  • Electrophoresis, Gel, Two-Dimensional 51%
  • Ampholyte Mixtures 41%
  29 Citations (Scopus)

• Clinical proteomics

  Celis, J. E. & Moreira, J. M. A., 1 Oct 2008, In: Molecular and Cellular Proteomics. 7, 10, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

  8 Citations (Scopus)

• Proteomic strategies in bladder cancer: From tissue to fluid and back

  Gromov, P., Moreira, J. M. A., Gromova, I. & Celis, J. E., 1 Jul 2008, In: Proteomics - Clinical Applications. 2, 7-8, p. 974-988 15 p.

  Research output: Contribution to journal › Review › peer-review

  • Back 100%
  • Urinary Bladder Neoplasms 96%
  • Proteomics 92%
  • Marker 88%
  • Tumor Biomarkers 65%
  9 Citations (Scopus)
• 2007

  Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia

  Celis, J. E., Gromova, I., Cabezón, T., Gromov, P., Shen, T., Timmermans, V. J. M., Rank, F. & Moreira, J., 2007, In: Molecular Oncology. 1, 1, p. 97-119 23 p.

  Research output: Contribution to journal › Journal article › Research

  • Metaplasia 100%
  • Hyperplasia 80%
  • Breast 69%
  • Carcinoma 48%
  • Carcinoma in Situ 41%
  26 Citations (Scopus)

• Identification of a subset of breast carcinomas characterized by expression of cytokeratin 15: Relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease

  Celis, J. E., Gromova, I., Cabezón, T., Gromov, P., Shen, T., Timmermans-Wielenga, V., Rank, F. & Moreira, J. M. A., 1 Jan 2007, In: Molecular Oncology. 1, 3, p. 321-349 29 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Keratin-15 100%
  • Stem Cells 41%
  • Breast Neoplasms 36%
  • Phenotype 19%
  • Breast 14%
  22 Citations (Scopus)
• 2006

  Apocrine cysts of the breast: Biomarkers, origin, enlargement, and relation with cancer phenotype

  Celis, J. E., Gromov, P., Moreira, J. M. A., Cabezón, T., Friis, E., Vejborg, I. M. M., Proess, G., Rank, F. & Gromova, I., 1 Mar 2006, In: Molecular and Cellular Proteomics. 5, 3, p. 462-483 22 p.

  Research output: Contribution to journal › Review › peer-review

  • Breast Cyst 100%
  • Biological Marker 55%
  • Cysts 40%
  • Biomarkers 39%
  • Phenotype 36%
  33 Citations (Scopus)

• Determination of Antibody Specificity by Western Blotting

  Celis, J. E., Moreira, J. M. A. & Gromov, P., 1 Dec 2006, Cell Biology, Four-Volume Set. Elsevier Science Inc., Vol. 1. p. 527-532 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  • Antibody Specificity 100%
  • Collodion 70%
  • Electrophoresis, Gel, Two-Dimensional 64%
  • Western Blotting 56%
  • Membranes 49%
  6 Citations (Scopus)

• Molecular pathology of breast apocrine carcinomas: A protein expression signature specific for benign apocrine metaplasia

  Celis, J. E., Gromova, I., Gromov, P., Cabezón, T., Friis, E., Rank, F. & Moreira, J., 2006, In: FEBS Letters. 580, 12, p. 2935-2944 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Molecular Pathology 100%
  • Metaplasia 95%
  • 15-hydroxyprostaglandin dehydrogenase 72%
  • Coenzyme A 72%
  • Breast Neoplasms 55%
  39 Citations (Scopus)