Jakob Werner Hansen

Research output

Research output per year 2009 2016 2017 2018 2020

• 16 Journal article
• 1 Comment/debate
• 1 Conference abstract in journal
• 1 Review

Research output per year

Research output per year

Search results

• 2020

  The diagnostic and prognostic role of flow cytometry in idiopathic and clonal cytopenia of undetermined significance (ICUS/CCUS): A single-center analysis of 79 patients

  Dimopoulos, K., Hansen, O. K., Sjö, L. D., Saft, L., Schjødt, I. M., Werner Hansen, J. & Grønbaek, K., 1 May 2020, In: Cytometry. Part B: Clinical Cytometry.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Flow Cytometry 100%
  • Bone Marrow 21%
  • Leukemia, Myelomonocytic, Chronic 21%
  • GATA2 Deficiency 20%
  • Myelodysplastic Syndromes 16%
  2 Citations (Scopus)
• 2019

  Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

  Gillberg, L., Ørskov, A. D., Nasif, A., Ohtani, H., Madaj, Z., Hansen, J. W., Rapin, N., Mogensen, J. B., Liu, M., Dufva, I. H., Lykkesfeldt, J., Hajkova, P., Jones, P. A. & Grønbæk, K., 17 Oct 2019, In: Clinical Epigenetics. 11, 1, p. 143-153 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Azacitidine 100%
  • Ascorbic Acid 74%
  • Epigenomics 65%
  • 5-Methylcytosine 53%
  • 5-hydroxymethylcytosine 45%
  19 Citations (Scopus)
• 2018

  Clinical Impact of Clonal Hematopoiesis after Autologous Stem Cell Transplantation for Lymphoma: A National Population-Based Cohort Study

  Husby, S., Francesco, F., Nielsen, C., Sorensen, B., Baech, J., Hansen, J. W., Gonzalez, G. G. R., Arboe, B., Andersen, L. P., Hastrup, E. K., Fischer-Nielsen, A., Saekmose, S. G., Hansen, P. B., Christiansen, I., Clasen-Linde, E., Knudsen, L. M., Grell, K., Segel, E. K., Ebbesen, L. H., Thorsgaard, M., & 6 othersJosefsson, P. L., El-Galaly, T. C., Brown, P. D. N., Weisenfeldt, J., Larsen, T. S. & Gronbaek, K., 2018, In: Blood. 132, Suppl 1, p. 607 1 p.

  Research output: Contribution to journal › Conference abstract in journal › Research

• Long-term clinical outcomes of patients with hematologically unexplained cytopenia after routine assessment: A single center study

  Johansen, M. M., Andersen, M. A., Grønbaek, K. & Hansen, J. W., Nov 2018, In: European Journal of Haematology. 101, 5, p. 595–603 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Rheumatic Diseases 100%
  • Mortality 94%
  • Liver Neoplasms 93%
  • Liver Diseases 78%
  • Incidence 75%
  1 Citation (Scopus)

• Treatment strategies, outcomes and prognostic factors in 291 patients with secondary CNS involvement by diffuse large B-cell lymphoma

  El-Galaly, T. C., Cheah, C. Y., Bendtsen, M. D., Nowakowski, G. S., Kansara, R., Savage, K. J., Connors, J. M., Sehn, L. H., Goldschmidt, N., Shaulov, A., Farooq, U., Link, B. K., Ferreri, A. J. M., Calimeri, T., Cecchetti, C., Dann, E. J., Thompson, C. A., Inbar, T., Maurer, M. J., Gade, I. L., & 14 othersJuul, M. B., Hansen, J. W., Holmberg, S., Larsen, T. S., Cordua, S., Mikhaeel, N. G., Hutchings, M., Seymour, J. F., Clausen, M. R., Smith, D., Opat, S., Gilbertson, M., Thanarajasingam, G. & Villa, D., 2018, In: European Journal of Cancer. 93, p. 57-68 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lymphoma, Large B-Cell, Diffuse 100%
  • Methotrexate 28%
  • Survival 27%
  • Status Epilepticus 11%
  • Recurrence 11%
  25 Citations (Scopus)
• 2017

  Anemia is present years before myelodysplastic syndrome diagnosis: Results from the pre-diagnostic period

  Hansen, J. W., Sandholdt, H., Siersma, V., Ørskov, A. D., Holmberg, S., Bjerrum, O. W., Hasselbalch, H. C., Olivarius, N. D. F., Grønbæk, K. & Andersen, C. L., Jul 2017, In: American Journal of Hematology. 92, 7, p. E130-E132 3 p.

  Research output: Contribution to journal › Comment/debate › Research › peer-review

  1 Citation (Scopus)

• Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma

  Wedge, E., Hansen, J. W., Garde, C., Asmar, F., Tholstrup, D., Kristensen, S. S., Munch-Petersen, H. D., Ralfkiaer, E., Brown, P., Grønbaek, K. & Kristensen, L. S., Jul 2017, In: American Journal of Hematology. 92, 7, p. 689-694 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cell-Free Nucleic Acids 100%
  • Lymphoma, Large B-Cell, Diffuse 89%
  • Methylation 35%
  • Biopsy 19%
  • DNA 13%
  20 Citations (Scopus)

• TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy

  Eskelund, C. W., Dahl, C., Hansen, J. W., Westman, M., Kolstad, A., Pedersen, L. B., Montano-Almendras, C. P., Husby, S., Freiburghaus, C., Ek, S., Pedersen, A., Niemann, C., Raty, R., Brown, P., Geisler, C. H., Andersen, M. K., Guldberg, P., Jerkeman, M. & Grønbæk, K., 2017, In: Blood. 130, 17, p. 1903-1910 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Mantle-Cell Lymphoma 100%
  • Mutation 64%
  • Cytarabine 41%
  • Standard of Care 37%
  • P-30 composite resin 30%
  140 Citations (Scopus)
• 2016

  Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma

  Sommer Kristensen, L., Hansen, J. W., Kristensen, S. S., Tholstrup, D., Harsløf, L. B. S., Pedersen, O. B., De Nully Brown, P. & Grønbæk, K., 7 Sept 2016, In: Clinical Epigenetics. 8, 11 p., 95.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cell-Free Nucleic Acids 100%
  • Lymphoma, Large B-Cell, Diffuse 89%
  • Methylation 71%
  • DNA Methylation 21%
  • Rituximab 7%
  34 Citations (Scopus)

  182 Downloads (Pure)

• Immune Mechanisms in Myelodysplastic Syndrome

  Glenthøj, A., Ørskov, A. D., Hansen, J. W., Hadrup, S. R., O'Connell, C. & Grønbæk, K., 15 Jun 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 13 p., 944.

  Research output: Contribution to journal › Review › peer-review

  • Growth Factor 100%
  • Pipeline 98%
  • Myelodysplastic Syndromes 95%
  • Mutation 71%
  • Intercellular Signaling Peptides and Proteins 64%
  30 Citations (Scopus)

• Mutations in idiopathic cytopenia of undetermined significance assist diagnostics and correlate to dysplastic changes

  Hansen, J. W., Westman, M. K., Sjö, L. D., Saft, L., Sommer Kristensen, L., Ørskov, A. D., Treppendahl, M., Andersen, M. K. & Grønbaek, K., 1 Dec 2016, In: American Journal of Hematology. 91, 12, p. 1234-1238 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Mutation 100%
  • Genes 23%
  • Myelodysplastic Syndromes 22%
  • Hematologic Neoplasms 20%
  • Bone Marrow 14%
  21 Citations (Scopus)

• The value of routine bone marrow biopsy in patients with diffuse large B-cell lymphoma staged with PET/CT: a Danish-Canadian study

  Alzahrani, M., El-Galaly, T. C., Hutchings, M., Hansen, J. W., Loft, A., Johnsen, H. E., Iyer, V., Wilson, D., Sehn, L. H., Savage, K. J., Connors, J. M., Gascoyne, R. D., Johansen, P., Clasen-Linde, E., Brown, P. & Villa, D., 18 Jun 2016, In: Annals of Oncology. 27, 6, p. 1095-9 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lymphoma, Large B-Cell, Diffuse 100%
  • Positron-Emission Tomography 82%
  • Bone Marrow 65%
  • Tomography 60%
  • Biopsy 53%
  23 Citations (Scopus)

• Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations

  Aslan, D., Garde, C., Nygaard, M. K., Helbo, A. S., Dimopoulos, K., Hansen, J. W., Severinsen, M. T., Treppendahl, M. B., Sjø, L. D., Grønbæk, K. & Sommer Kristensen, L., 2016, In: OncoTarget. 7, 9, p. 9951-63 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Spliceosomes 100%
  • Myelodysplastic Syndromes 81%
  • MicroRNAs 61%
  • Down-Regulation 50%
  • Mutation 40%
  15 Citations (Scopus)

  113 Downloads (Pure)

• Uterine, but not ovarian, female reproductive organ involvement at presentation by diffuse large B-cell lymphoma is associated with poor outcomes and a high frequency of secondary CNS involvement

  El-Galaly, T. C., Cheah, C. Y., Hutchings, M., Mikhaeel, N. G., Savage, K. J., Sehn, L. H., Barrington, S. F., Hansen, J. W., Poulsen, M. Ø., Smith, D. L., Rady, K., Mylam, K. J., Larsen, T. S., Holmberg, S., Juul, M. B., Cordua, S., Clausen, M. R., Jensen, K. B., Boegsted, M., Johnsen, H. E., & 4 othersSeymour, J. F., Connors, J. M., Brown, P. D. N. & Villa, D., 1 Dec 2016, In: British Journal of Haematology. 175, 5, p. 876-883 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lymphoma, Large B-Cell, Diffuse 100%
  • Genitalia 82%
  • Central Nervous System 65%
  • Uterus 16%
  • Multivariate Analysis 12%
  18 Citations (Scopus)
• 2015

  Outcome prediction by extranodal involvement, IPI, and R-IPI in the PET/CT and rituximab era: A Danish-Canadian study of 443 patients with diffuse-large B-cell lymphoma

  El-Galaly, T. C., Villa, D., Alzahrani, M., Hansen, J. W., Sehn, L. H., Wilson, D., de Nully Brown, P., Loft, A., Iyer, V., Johnsen, H. E., Savage, K. J., Connors, J. M. & Hutchings, M., Nov 2015, In: American Journal of Hematology. 90, 11, p. 1041–1046

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lymphoma, Large B-Cell, Diffuse 100%
  • Rituximab 96%
  • Progression-Free Survival 80%
  • British Columbia 22%
  • Positron Emission Tomography Computed Tomography 19%
  41 Citations (Scopus)

• YKL-40 and genetic status of CHI3L1 in a large group of asthmatics

  Hansen, J. W., Thomsen, S. F., Porsbjerg, C., Rasmussen, L. M., Harmsen, L., Johansen, J. S. & Backer, V., 2015, In: European Clinical Respiratory Journal. 2, p. 1-8 8 p., 25117.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Asthma 100%
  • Single Nucleotide Polymorphism 41%
  • Rhinitis 34%
  • Serum 26%
  • Genotype 14%
• 2014

  Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma

  Kristensen, L. S., Asmar, F., Dimopoulos, K., Nygaard, M. K., Aslan, D., Hansen, J. W., Ralfkiaer, E. & Grønbæk, K., 2014, In: OncoTarget. 5, 20, p. 9798-810 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lymphoma, Large B-Cell, Diffuse 100%
  • Methylation 80%
  • Survival 49%
  • Alleles 27%
  • Multiple Myeloma 25%
  27 Citations (Scopus)
• 2010

  Rhinitis: a complication to asthma

  Hansen, J. W., Thomsen, S. F., Nolte, H. & Backer, V., Jul 2010, In: Allergy. 65, 7, p. 883-8 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Rhinitis 100%
  • Asthma 67%
  • Quality of Life 23%
  • Methacholine Chloride 8%
  • Respiratory Function Tests 8%
  12 Citations (Scopus)
• 2009

  Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

  Gudbjartsson, D. F., Bjornsdottir, U. S., Halapi, E., Helgadottir, A., Sulem, P., Jonsdottir, G. M., Thorleifsson, G., Helgadottir, H., Steinthorsdottir, V., Stefansson, H., Williams, C., Hui, J., Beilby, J., Warrington, N. M., James, A., Palmer, L. J., Koppelman, G. H., Heinzmann, A., Krueger, M., Boezen, H. M., & 53 othersWheatley, A., Altmuller, J., Shin, H. D., Uh, S-T., Cheong, H. S., Jonsdottir, B., Gislason, D., Park, C-S., Rasmussen, L. M., Porsbjerg, C., Hansen, J. W., Backer, V., Werge, T., Janson, C., Jönsson, U-B., Ng, M. C. Y., Chan, J., So, W. Y., Ma, R., Shah, S. H., Granger, C. B., Quyyumi, A. A., Levey, A. I., Vaccarino, V., Reilly, M. P., Rader, D. J., Williams, M. J. A., van Rij, A. M., Jones, G. T., Trabetti, E., Malerba, G., Pignatti, P. F., Boner, A., Pescollderungg, L., Girelli, D., Olivieri, O., Martinelli, N., Ludviksson, B. R., Ludviksdottir, D., Eyjolfsson, G. I., Arnar, D., Thorgeirsson, G., Deichmann, K., Thompson, P. J., Wjst, M., Hall, I. P., Postma, D. S., Gislason, T., Gulcher, J., Kong, A., Jonsdottir, I., Thorsteinsdottir, U. & Stefansson, K., Mar 2009, In: Nature Genetics. 41, 3, p. 342-7 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Eosinophils 100%
  • Single Nucleotide Polymorphism 86%
  • Asthma 80%
  • Myocardial Infarction 75%
  • Interleukin-33 28%
  570 Citations (Scopus)