Jakob Schmidt Jespersen

2019

Cerebral malaria is associated with differential cytoadherence to brain endothelial cells

Storm, J., Jespersen, J. S., Seydel, K. B., Szestak, T., Mbewe, M., Chisala, N. V., Phula, P., Wang, C. W., Taylor, T. E., Moxon, C. A., Lavstsen, T. & Craig, A. G., 1 Feb 2019, In: EMBO Molecular Medicine. 2019, 11, 15 p., e9164.

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

43 Downloads (Pure)

2018

Antibodies to intercellular adhesion molecule 1-binding Plasmodium falciparum erythrocyte membrane protein 1-DBLβ are biomarkers of protective immunity to malaria in a cohort of young children from Papua New Guinea

Tessema, S. K., Utama, D., Chesnokov, O., Hodder, A. N., Lin, C. S., Harrison, G. L. A., Jespersen, J. S., Petersen, B., Tavul, L., Siba, P., Kwiatkowski, D., Lavstsen, T., Hansen, D. S., Oleinikov, A. V., Mueller, I. & Barry, A. E., 1 Aug 2018, In: Infection and Immunity. 86, 8, p. 1-14 14 p., e00485-17.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

2017

Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites

Mkumbaye, S. I., Minja, D. T. R., Jespersen, J. S., Alifrangis, M., Kavishe, R. A., Mwakalinga, S. B., Lusingu, J. P., Theander, T. G., Lavstsen, T. & Wang, C. W., 10 Feb 2017, In: Malaria Journal. 16, 1, 8 p., 69.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

115 Downloads (Pure)

Parasites causing cerebral falciparum malaria bind multiple endothelial receptors and express EPCR and ICAM-1-binding PfEMP1

Tuikue Ndam, N., Moussiliou, A., Lavstsen, T., Kamaliddin, C., Jensen, A. T. R., Mama, A., Tahar, R., Wang, C. W., Jespersen, J. S., Alao, J. M., Gamain, B., Theander, T. G. & Deloron, P., 15 Jun 2017, In: The Journal of Infectious Diseases. 215, 12, p. 1918-1925 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Plasmodium falciparum causing febrile infections express EPCR- binding PfEMP1

Mkumbaye, S., Wang, C. W., Jespersen, J. S., Petersen, J. E. V., Kavishe, R., Lusingu, J., Theander, T. G. & Lavstsen, T., Oct 2017, In: Tropical Medicine & International Health. 22, S1, p. 7-7 1S3.3.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria

Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K., & 1 othersJensen, A. T. R., 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

64 Citations (Scopus)

441 Downloads (Pure)

The Severity of Plasmodium falciparum infection is associated with transcript levels of var genes encoding endothelial protein C receptor-binding P. falciparum erythrocyte membrane protein 1

Mkumbaye, S. I., Wang, C. W., Lyimo, E., Jespersen, J. S., Manjurano, A., Mosha, J., Kavishe, R. A., Mwakalinga, S. B., Minja, D. T. R., Lusingu, J. P., Theander, T. G. & Lavstsen, T., 1 Apr 2017, In: Infection and Immunity. 85, 4, 14 p., 4e00841-16.

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

2016

Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains

Jespersen, J. S., Wang, C. W., Mkumbaye, S. I., Minja, D. T., Petersen, B., Turner, L., Petersen, J. E., Lusingu, J. P., Theander, T. G. & Lavstsen, T., 1 Aug 2016, In: EMBO Molecular Medicine. 8, 8, p. 839-850 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

53 Citations (Scopus)

118 Downloads (Pure)

2015

Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA

Doritchamou, J., Sabbagh, A., Jespersen, J. S., Renard, E., Salanti, A., Nielsen, M. A., Deloron, P. & Tuikue Ndam, N., 22 Sept 2015, In: PLOS ONE. 10, 9, 14 p., e0137695.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria

Lau, C. K. Y., Turner, L., Jespersen, J. S., Lowe, E. D., Petersen, B., Wang, C. W., Petersen, J. E. V., Lusingu, J., Theander, T. G., Lavstsen, T. & Higgins, M. K., 14 Jan 2015, In: Cell Host & Microbe. 17, 1, p. 118-29 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

98 Citations (Scopus)

2014

DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families

Pedersen, A. F. S., Lavstsen, T., Rask, T. S., Lisby, M., Salanti, A., Fordyce, S. L., Jespersen, J. S., Carter, R., Deitsch, K. W., Theander, T. G., Pedersen, A. G. & Arnot, D. E., Feb 2014, In: Nucleic Acids Research. 42, 4, p. 2270-81 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

2013

Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin

Bertin, G. I., Lavstsen, T., Guillonneau, F., Doritchamou, J., Wang, C. W., Jespersen, J. S., Ezimegnon, S., Fievet, N., Alao, M. J., Lalya, F., Massougbodji, A., Ndam, N. T., Theander, T. G. & Deloron, P., 29 Jul 2013, In: P L o S One. 8, 7, p. e68368

Research output: Contribution to journal › Journal article › Research › peer-review

44 Citations (Scopus)

Severe malaria is associated with parasite binding to endothelial protein C receptor

Turner, L., Lavstsen, T., Berger, S. S., Wang, C. W., Petersen, J. E. V., Avril, M., Brazier, A. J., Freeth, J., Jespersen, J. S., Nielsen, M. A., Magistrado, P., Lusingu, J., Smith, J. D., Higgins, M. K. & Theander, T. G., 27 Jun 2013, In: Nature. 498, 7455, p. 502-5 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

314 Citations (Scopus)

2012

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children

Lavstsen, T., Turner, L., Saguti, F., Magistrado, P. A., Rask, T. S., Jespersen, J. S., Wang, C. W., Berger, S. S., Baraka, V., Marquard, A. M., Seguin-Orlando, A., Willerslev, E., Gilbert, T., Lusingu, J. P. A. & Theander, T. G., 26 Jun 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1791-E1800 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

173 Citations (Scopus)

Jakob Schmidt Jespersen

Research output

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