Christian Holmberg

2019

Comprehensive profiling of the fission yeast transcription start site activity during stress and media response

Thodberg, M., Thieffry, A., Bornholdt, J., Boyd, M., Holmberg, C., Azad, A., Workman, C. T., Chen, Y., Ekwall, K., Nielsen, O. & Sandelin, A., 28 Feb 2019, In: Nucleic Acids Research. 47, 4, p. 1671-1691 21 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

2017

Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication

Fleck, O., Fahnøe, U., Løvschal, K. V., Gasasira, M.-F. U., Marinova, I. N., Kragelund, B. B., Carr, A. M., Hartsuiker, E., Holmberg, C. & Nielsen, O., May 2017, In: Genes. 8, 5, 14 p., 128.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

311 Downloads (Pure)

UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1

Poulsen, E. G., Kampmeyer, C., Kriegenburg, F., Johansen, J. V., Hofmann, K., Holmberg, C. & Hartmann-Petersen, R., 1 Jan 2017, In: Cell Stress & Chaperones. 22, 1, p. 143-154 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2015

Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing

Marinova, I. N., Engelbrecht, J., Ewald, A., Langholm, L. L., Holmberg, C. H., Kragelund, B. B., Gordon, C., Nielsen, O. & Hartmann-Petersen, R., 6 Feb 2015, In: P L o S One. 10, 2, 15 p., e0117779.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

1062 Downloads (Pure)

2014

Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools

Vejrup-Hansen, R., Fleck, O., Landvad, K., Fahnøe, U., Broendum, S. S., Schreurs, A.-S., Kragelund, B. B., Carr, A. M., Holmberg, C. H. & Nielsen, O., Jun 2014, In: Journal of Cell Science. 127, p. 2460-2470 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

2013

Spd1 accumulation causes genome instability independently of ribonucleotide reductase activity but functions to protect the genome when deoxynucleotide pools are elevated

Fleck, O., Vejrup-Hansen, R., Watson, A., Carr, A. M., Nielsen, O. & Holmberg, C. H., 1 Nov 2013, In: Journal of Cell Science. 126, p. 4985-4994 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

2012

Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption

Beck, H., Nähse-Kumpf, V., Larsen, M. S. Y., O'Hanlon, K. A., Patzke, S., Holmberg, C. H., Mejlvang, J., Groth, A., Nielsen, O., Syljuåsen, R. G. & Sørensen, C. S., Oct 2012, In: Molecular and Cellular Biology. 32, 20, p. 4226-4236 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

150 Citations (Scopus)

Replication: DNA Building Block Synthesis On Demand

Holmberg, C. & Nielsen, O., 24 Apr 2012, In: Current Biology. 22, 8, p. R271-R272 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

2011

Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination

Vejrup-Hansen, R., Mizuno, K., Miyabe, I., Fleck, O., Holmberg, C., Murray, J. M., Carr, A. M. & Nielsen, O., 7 Mar 2011, In: DNA Repair. 10, 3, p. 283-95 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

2010

Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast

Moss, J., Tinline-Purvis, H., Walker, C. A., Folkes, L. K., Stratford, M. R., Hayles, J., Hoe, K.-L., Kim, D.-U., Park, H.-O., Kearsey, S. E., Fleck, O., Holmberg, C., Nielsen, O. & Humphrey, T. C., 1 Dec 2010, In: Genes & Development. 24, 23, p. 2705-16 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

43 Citations (Scopus)

Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms

Nestoras, K., Mohammed, A. H., Schreurs, A.-S., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, C., Chahwan, C., Holmberg, C., Kragelund, B. B., Nielsen, O., Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

33 Citations (Scopus)

2006

Genome-wide identification of pheromone-targeted transcrption in fission yeast

Xue-Franzen, Y., Kjærulff, S., Holmberg, C., Wright, A. & Nielsen, O., 2006, In: BMC Genomics. 7, p. 303

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

901 Downloads (Pure)

2005

Conditional E2F1 activation in transgenic mice causes testicular atrophy and dysplasia mimicking human CIS.

Agger, K., Santoni-Rugiu, E., Holmberg, C., Karlström, O. & Helin, K., 2005, In: Oncogene. 24, 5, p. 780-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Ddb1 controls genome stability and meiosis in fission yeast

Holmberg, C. H., Fleck, O., Hansen, H. A., Liu, C., Slaaby, R., carr, A. M. & Nielsen, O., 2005, In: Genes & Development. 19, 7, p. 853-862

Research output: Contribution to journal › Journal article › Research › peer-review

79 Citations (Scopus)

Depletion of the AP-1 repressor JDP2 induces cell death similar to apoptosis

Lerdrup, M., Holmberg, C. H., Dietrich, N., Shaulian, E., Herdegen, T., Jaattela, M. & Kallunki, T., 2005, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1745, 1, p. 29-37

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Mangel på DNA-byggesten kan give kræft.

Holmberg, C. H. & Nielsen, O., 2005, In: Aktuel Naturvidenskab. 3, p. 22-23

Research output: Contribution to journal › Journal article › Research

Transactivation of Schizosaccharomyces pombe cdt2⁺ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase

Liu, C., Poitelea, M., Watson, A., Yoshida, S.-H., Shimoda, C., Holmberg, C. H., Nielsen, O. & Carr, A. M., 2005, In: EMBO Journal. 24, p. 3940-3951

Research output: Contribution to journal › Journal article › Research › peer-review

79 Citations (Scopus)

2004

JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways

Dietrich, N., Thastrup, J., Holmberg, C. H., Gyrd-Hansen, M., Fehrenbacher, N., Lademann, U., Lerdrup, M., Herdegen, T., Jäättelä, M. & Kallunki, T., 2004, In: Cell Death and Differentiation. 11, 3, p. 301-313 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

53 Citations (Scopus)

2002

A Novel Specific Role for IB Kinase Complex-associated Protein in Cytosolic Stress Signaling

Holmberg, C. H., Katz, S., Lerdrup, M., Herdegen, T., Jaattela, M., Aronheim, A. & Kallunki, T., 2002, In: The Journal of Biological Chemistry. Vol. 277 (35), p. 31918-28

Research output: Contribution to journal › Journal article › Research › peer-review

1998

E2F-1-Induced p53-independent apoptosis in transgenic mice

Holmberg, C. H., Helin, K., Sehested, M. & Karlström, O., 1998, In: Oncogene. 17, 2, p. 143-155 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

111 Citations (Scopus)

Christian Holmberg

Research output

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