Brian Tate Weinert

2019

Acetylation of intrinsically disordered regions regulates phase separation

Saito, M., Hess, D., Eglinger, J., Fritsch, A. W., Kreysing, M., Weinert, B. T., Choudhary, C. & Matthias, P., Jan 2019, In: Nature Chemical Biology. 15, 1, p. 51-61

Research output: Contribution to journal › Journal article › Research › peer-review

60 Citations (Scopus)

Analysis and Interpretation of Protein Post-Translational Modification Site Stoichiometry

Prus, G., Hoegl, A., Weinert, B. T. & Choudhary, C., Nov 2019, In: Trends in Biochemical Sciences. 44, 11, p. 943-960

Research output: Contribution to journal › Review › peer-review

13 Citations (Scopus)

Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation

Hansen, B. K., Gupta, R., Baldus, L., Lyon, D., Narita, T., Lammers, M., Choudhary, C. & Weinert, B. T., 1 Dec 2019, In: Nature Communications. 10, 11 p., 1055.

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

31 Downloads (Pure)

Functions and mechanisms of non-histone protein acetylation

Narita, T., Weinert, B. T. & Choudhary, C., 1 Mar 2019, In: Nature Reviews. Molecular Cell Biology. 20, p. 156-174 19 p.

Research output: Contribution to journal › Review › peer-review

175 Citations (Scopus)

Retraction

Kaidi, A., Weinert, B. T., Choudhary, C. & Jackson, S. P., 19 Apr 2019, In: Science. 364, 6437, p. 247 1 p.

Research output: Contribution to journal › Comment/debate › Research

2018

Benchmarking common quantification strategies for large-scale phosphoproteomics

Hogrebe, A., von Stechow, L., Bekker-Jensen, D. B., Weinert, B. T., Kelstrup, C. D. & Olsen, J. V., 2018, In: Nature Communications. 9, 1, p. 1-13 1045.

Research output: Contribution to journal › Journal article › Research › peer-review

101 Citations (Scopus)

87 Downloads (Pure)

Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome

Weinert, B. T., Narita, T., Satpathy, S., Srinivasan, B., Hansen, B. K., Schölz, C., Hamilton, W. B., Zucconi, B. E., Wang, W. W., Liu, W. R., Brickman, J. M., Kesicki, E. A., Lai, A., Bromberg, K. D., Cole, P. A. & Choudhary, C., 2018, In: Cell. 174, 1, p. 231-244.e12 27 p.

Research output: Contribution to journal › Journal article › Research › peer-review

91 Citations (Scopus)

2017

Accurate quantification of site-specific acetylation stoichiometry reveals the impact of sirtuin deacetylase CobB on the E. coli acetylome

Weinert, B. T., Satpathy, S., Hansen, B. K., Lyon, D., Jensen, L. J. & Choudhary, C. R., May 2017, In: Molecular and Cellular Proteomics. 16, p. 759-769

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Lasko, L. M., Jakob, C. G., Edalji, R. P., Qiu, W., Montgomery, D., Digiammarino, E. L., Hansen, T. M., Risi, R. M., Frey, R., Manaves, V., Shaw, B., Algire, M., Hessler, P., Lam, L. T., Uziel, T., Faivre, E., Ferguson, D., Buchanan, F. G., Martin, R. L. & Torrent, M. & 16 others, Chiang, G. G., Karukurichi, K., Langston, J. W., Weinert, B. T., Choudhary, C., de Vries, P., Van Drie, J. H., McElligott, D., Kesicki, E., Marmorstein, R., Sun, C., Cole, P. A., Rosenberg, S. H., Michaelides, M. R., Lai, A. & Bromberg, K. D., 5 Oct 2017, In: Nature. 550, 7674, p. 128-132 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

213 Citations (Scopus)

2016

A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex

Starnes, L. M., Su, D., Pikkupeura, L. M., Weinert, B. T., Santos, M. A., Mund, A., Soria, R., Cho, Y.-W., Pozdnyakova, I., Kubec Højfeldt, M., Lages Lino Vala, A., Yang, W., López-Méndez, B., Lee, J.-E., Peng, W., Yuan, J., Ge, K., Montoya, G., Nussenzweig, A. & Choudhary, C. R. & 1 others, Daniel, J. A., 15 Jan 2016, In: Genes & Development. 30, 2, p. 149-163 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

72 Downloads (Pure)

2015

Acetylation site specificities of lysine deacetylase inhibitors in human cells

Schölz, C., Weinert, B. T., Wagner, S. A., Beli, P., Miyake, Y., Qi, J., Jensen, L. J., Streicher, W., McCarthy, A. R., Westwood, N. J., Lain, S., Cox, J., Matthias, P., Mann, M., Bradner, J. E. & Choudhary, C. R., 1 Apr 2015, In: Nature Biotechnology. 33, p. 415–423

Research output: Contribution to journal › Journal article › Research › peer-review

159 Citations (Scopus)

Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions

Weinert, B. T., Moustafa, T., Iesmantavicius, V., Zechner, R. & Choudhary, C. R., 3 Nov 2015, In: E M B O Journal. 34, 21, p. 2620-2632 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

77 Citations (Scopus)

Avoiding abundance bias in the functional annotation of posttranslationally modified proteins

Schölz, C., Lyon, D., Refsgaard, J. C., Jensen, L. J., Choudhary, C. R. & Weinert, B. T., 1 Nov 2015, In: Nature Methods. 12, p. 1003-4 2 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

24 Citations (Scopus)

Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, J. V., Choudhary, C. R., Bekker-Jensen, S. & Mailand, N., 8 Jan 2015, In: Molecular Cell. 57, 1, p. 150-64 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

79 Citations (Scopus)

2014

Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae

Weinert, B. T., Iesmantavicius, V., Moustafa, T., Schölz, C., Wagner, S. A., Magnes, C., Zechner, R. & Choudhary, C. R., 31 Jan 2014, In: Molecular Systems Biology. 10, 1, p. 716 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

146 Citations (Scopus)

Convergence of Ubiquitylation and Phosphorylation Signaling in Rapamycin-Treated Yeast Cells

Iesmantavicius, V., Weinert, B. T. & Choudhary, C. R., Aug 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1979-92 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

The growing landscape of lysine acetylation links metabolism and cell signalling

Choudhary, C. R., Weinert, B. T., Nishida, Y., Verdin, E. & Mann, M., Aug 2014, In: Nature Reviews. Molecular Cell Biology. 15, 8, p. 536-50 15 p.

Research output: Contribution to journal › Review › peer-review

725 Citations (Scopus)

2013

Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli

Weinert, B. T., Iesmantavicius, V., Wagner, S. A., Schölz, C., Gummesson, B., Beli, P., Nyström, T. & Choudhary, C. R., 25 Jul 2013, In: Molecular Cell. 51, 2, p. 265-272 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

252 Citations (Scopus)

Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation

Weinert, B. T., Schölz, C., Wagner, S. A., Iesmantavicius, V., Su, D., Daniel, J. A. & Choudhary, C. R., 29 Aug 2013, In: Cell Reports. 4, 4, p. 842-51 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

377 Citations (Scopus)

2012

Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae

Henriksen, P., Wagner, S. A., Weinert, B. T., Sharma, S., Bacinskaja, G., Rehman, M., Juffer, A. H., Walther, T. C., Lisby, M. & Choudhary, C. R., Nov 2012, In: Molecular & Cellular Proteomics. 11, 11, p. 1510-1522 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

182 Citations (Scopus)

Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues

Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, M. L., Olsen, J. V., Brakebusch, C. & Choudhary, C. R., Dec 2012, In: Molecular & Cellular Proteomics.

Research output: Contribution to journal › Journal article › Research › peer-review

189 Citations (Scopus)

Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns

Lundby, A., Hansen, K. L., Weinert, B. T., Breinholt Bekker-Jensen, D., Secher, A., Skovgaard, T., Kelstrup, C., Dmytriyev, A., Choudhary, C. R., Lundby, C. & Olsen, J. V., 30 Aug 2012, In: Cell Reports. 2, 2, p. 419-431 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

355 Citations (Scopus)

Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3

Sol, E.-R. M., Wagner, S. A., Weinert, B. T., Kumar, A., Kim, H.-S., Deng, C.-X. & Choudhary, C. R., 7 Dec 2012, In: PloS one. 7, 12, p. e50545

Research output: Contribution to journal › Journal article › Research › peer-review

97 Citations (Scopus)

Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response

Beli, P., Lukashchuk, N., Wagner, S. A., Weinert, B. T., Olsen, J. V., Baskcomb, L., Mann, M., Jackson, S. P. & Choudhary, C. R., 27 Apr 2012, In: Molecular Cell. 46, 2, p. 212-25 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

196 Citations (Scopus)

2011

A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, M. L., Cox, J., Mann, M. & Choudhary, C. R., 1 Oct 2011, In: Molecular and Cellular Proteomics. 10, 10, p. M111.013284

Research output: Contribution to journal › Journal article › Research › peer-review

575 Citations (Scopus)

Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation

Weinert, B. T., Wagner, S. A., Horn, H., Henriksen, P., Liu, W. R., Olsen, J. V., Jensen, L. J. & Choudhary, C. R., 26 Jul 2011, In: Science Signaling. 4, 183, p. ra48

Research output: Contribution to journal › Journal article › Research › peer-review

187 Citations (Scopus)

Brian Tate Weinert

Research output

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