Bo Liang

Research output

Research output per year 2004 2004 2005 2013 2014 2015 2017

• 25 Journal article
• 1 Comment/debate

Research output per year

Research output per year

Search results

• 2017

  In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis

  Colman, M. A., Ni, H., Liang, B., Schmitt, N. & Zhang, H., Jun 2017, In: PLoS Computational Biology. 13, 6, 21 p., e1005587.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Genetic Variation 100%
  • genetic variation 78%
  • mutation 64%
  • Mutation 64%
  • Computer Simulation 61%
  19 Citations (Scopus)

  109 Downloads (Pure)
• 2015

  Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family

  Kanters, J. K., Skibsbye, L., Hedley, P. L., Dembic, M., Liang, B., Hagen, C. M., Eschen, O., Grunnet, M., Christiansen, M. & Jespersen, T., 17 Nov 2015, In: Scandinavian Journal of Clinical & Laboratory Investigation. 75, 8, p. 699-709 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Long QT Syndrome 100%
  • Mutation 64%
  • Phenotype 46%
  • HEK293 Cells 41%
  • Channelopathies 27%
  5 Citations (Scopus)

• Common and rare variants in SCN10A modulate the risk of atrial fibrillation.

  Jabbari, J., Olesen, M. S., Yuan, L., Nielsen, J. B., Liang, B., Macri, V., Christophersen, I. E., Nielsen, N., Sajadieh, A., Ellinor, P. T., Grunnet, M., Haunsø, S., Holst, A. G., Svendsen, J. H. & Jespersen, T., 4 Feb 2015, In: Circulation: Cardiovascular Genetics. 8, 1, p. 64-73 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Atrial Fibrillation 100%
  • Single Nucleotide Polymorphism 25%
  • NAV1.8 Voltage-Gated Sodium Channel 19%
  • RNA Splice Sites 12%
  • Linkage Disequilibrium 11%
  50 Citations (Scopus)

• Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

  Axelsen, L. N., Callø, K., Braunstein, T. H., Riemann, M., Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, K. B., Bartels, E. D., Baandrup, U., Jespersen, T., Nielsen, L. B., von Holstein-Rathlou, N-H. & Nielsen, M. S., 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Fructose 100%
  • Diet 60%
  • Fats 49%
  • Connexin 43 40%
  • Fibrosis 24%
  25 Citations (Scopus)

  185 Downloads (Pure)
• 2014

  Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

  Liang, B., Soka, M., Christensen, A. H., Olesen, M. S., Larsen, A. P., Knop, F. K., Wang, F., Nielsen, J. B., Andersen, M. N., Humphreys, D., Mann, S. A., Huttner, I. G., Vandenberg, J. I., Svendsen, J. H., Haunsø, S., Preiss, T., Seebohm, G., Olesen, S-P., Schmitt, N. & Fatkin, D., Feb 2014, In: Journal of Molecular and Cellular Cardiology. 67, p. 69-76 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Potassium Channels 100%
  • Genetic Variation 84%
  • Atrial Fibrillation 77%
  • Action Potentials 31%
  • Embryonic Structures 28%
  48 Citations (Scopus)

• G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

  Liang, B., Nissen, J. D., Laursen, M., Wang, X., Skibsbye, L., Hearing, M. C., Andersen, M. N., Rasmussen, H. B., Wickman, K., Grunnet, M., Olesen, S-P. & Jespersen, T., 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 175-84 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • tertiapin 100%
  • GTP-Binding Proteins 54%
  • Potassium 49%
  • otenzepad 35%
  • 1,3-dipropyl-8-cyclopentylxanthine 32%
  22 Citations (Scopus)

• Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant

  Yuan, L., Koivumaki, J., Liang, B., Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, J. H., Tfelt-Hansen, J., Maleckar, M., Schmitt, N., Olesen, M. S. & Jespersen, T., 15 Apr 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Brugada Syndrome 100%
  • Sodium Channels 85%
  • Computer Simulation 34%
  • Action Potentials 32%
  • Loss of Function Mutation 20%
  17 Citations (Scopus)
• 2013

  Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation

  Christophersen, I. E., Olesen, M. S., Liang, B., Andersen, M. N., Larsen, A. P., Nielsen, J. B., Haunsø, S., Olesen, S-P., Tveit, A., Svendsen, J. H. & Schmitt, N., 21 May 2013, In: European Heart Journal.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Genetic Variation 100%
  • Potassium 93%
  • Atrial Fibrillation 92%
  • Loss of Function Mutation 38%
  • Kv1.5 Potassium Channel 33%
  84 Citations (Scopus)

• GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology

  Wang, X., Liang, B., Skibsbye, L., Olesen, S-P., Grunnet, M. & Jespersen, T., Aug 2013, In: Journal of Cardiovascular Pharmacology. 62, 2, p. 192-8 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Purinergic P1 Receptors 100%
  • Electrophysiology 90%
  • Muscarinic Receptors 87%
  • Acetylcholine 74%
  • Membrane Potentials 58%
  17 Citations (Scopus)

• The Phenotype Characteristics of Type-13 Long QT Syndrome with mutation in KCNJ5 (Kir3.4-G387R)

  Wang, F., Liu, J., Hong, L., Liang, B., Graff, C., Yang, Y., Christiansen, M., Olesen, S-P., Zhang, L. & Kanters, J. K., Oct 2013, In: Heart rhythm : the official journal of the Heart Rhythm Society. 10, 10, p. 1500-1506 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Long QT Syndrome 100%
  • Phenotype 46%
  • Mutation 43%
  • Heart Rate 28%
  • Genotype 18%
  17 Citations (Scopus)
• 2012

  Functionally Selective AT(1) Receptor Activation Reduces Ischemia Reperfusion Injury

  Hostrup, A., Christensen, G. L., Bentzen, B. H., Liang, B., Aplin, M., Grunnet, M., Hansen, J. L. & Jespersen, T., Aug 2012, In: Cellular Physiology and Biochemistry. 30, 3, p. 642-652 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Reperfusion Injury 100%
  • Angiotensin II 99%
  • GTP-Binding Proteins 34%
  • seven-transmembrane G-protein-coupled receptor 18%
  • Arrestin 16%
  13 Citations (Scopus)

• High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation

  Olesen, M. S., Yuan, L., Liang, B., Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, S-P., Haunsø, S., Schmitt, N., Jespersen, T. & Svendsen, J. H., Aug 2012, In: Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Long QT syndrome type 3 100%
  • Long QT Syndrome 88%
  • Atrial Fibrillation 60%
  • Mutation 38%
  • Exome 13%
  96 Citations (Scopus)
• 2011

  Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation

  Olesen, M. S., Jespersen, T., Nielsen, J. B., Liang, B., Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, S-P., Haunsø, S., Schmitt, N. & Svendsen, J. H., 1 Mar 2011, In: Cardiovascular Research. 89, 4, p. 786-793 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Voltage-Gated Sodium Channel beta-3 Subunit 100%
  • Atrial Fibrillation 37%
  • Mutation 23%
  • Sodium Channels 14%
  • Sodium 10%
  91 Citations (Scopus)
• 2010

  Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome

  Yang, Y., Yang, Y., Liang, B., Liu, J., Li, J., Grunnet, M., Olesen, S-P., Rasmussen, H. B., Ellinor, P. T., Gao, L., Lin, X., Li, L., Wang, L., Xiao, J., Liu, Y., Liu, Y., Zhang, S., Liang, D., Peng, L., Jespersen, T., & 1 othersChen, Y-H., 11 Jul 2010, In: American Journal of Human Genetics. 86, 6, p. 872-80 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Long QT Syndrome 100%
  • Mutation 43%
  • Genetic Loci 37%
  • G Protein-Coupled Inwardly-Rectifying Potassium Channels 26%
  • Genes 24%
  147 Citations (Scopus)

• Sick sinus syndrome, progressive cardiac conduction disease, atrial flutter and ventricular tachycardia caused by a novel SCN5A mutation

  Holst, A. G., Liang, B., Jespersen, T., Bundgaard, H., Haunso, S., Svendsen, J. H. & Tfelt-Hansen, J., Apr 2010, In: Cardiology. 115, 4, p. 311-6 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Sick Sinus Syndrome 100%
  • Atrial Flutter 92%
  • Ventricular Tachycardia 78%
  • Heart Diseases 60%
  • Mutation 41%
  15 Citations (Scopus)
• 2009

  Routine Early Angioplasty after Fibrinolysis

  Wang, Z., Liang, B. & Mei, Q., 2009, In: New England Journal of Medicine. 361, 15, p. 1509 1 p.

  Research output: Contribution to journal › Comment/debate › Research › peer-review

  • Fibrinolysis 100%
  • Angioplasty 90%
  • Clopidogrel 83%
  • ST Elevation Myocardial Infarction 40%
  • Cardiogenic Shock 21%
• 2005

  A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation

  Xia, M., Jin, Q., Bendahhou, S., He, Y., Larroque, M-M., Chen, Y., Zhou, Q., Yang, Y., Liu, Y., Liu, B., Zhu, Q., Zhou, Y., Lin, J., Liang, B., Li, L., Dong, X., Pan, Z., Wang, R., Wan, H., Qiu, W., & 4 othersXu, W., Eurlings, P., Barhanin, J. & Chen, Y., 2005, In: Biochemical and Biophysical Research Communications. 332, 4, p. 1012-9 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gain of Function Mutation 100%
  • Andersen Syndrome 67%
  • Atrial Fibrillation 67%
  • Mutation 63%
  • Inwardly Rectifying Potassium Channels 52%
  294 Citations (Scopus)

• Cells and Angiogenic Cytokines in Therapeutic Angiogenesis for Ischemic Heart Disease

  Luo, Y., Zhang, D-F. & Liang, B., 2005, In: Xinxueguanbingxue Jinzhan. 26, 4, p. 422-425 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Changes of Ventricular Myocytes Membrane Capacitance in Rabbit with Myocardial Infarction and Effects of Carvedilol

  Niu, H-Y., Liang, B., Liu, N. & Li, Y., 2005, In: Tongji Daxue Xuebao (Yixue Ban). 26, 4, p. 21-23 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Effect of Exercise Testing on Short-term Heart Rate Variability in Patients with Coronary Heart Disease

  Niu, H-Y., Zhang, D-F., Liang, B., Wang, J., Zhou, H. & Zhuang, S-W., 2005, In: Tongji Daxue Xuebao (Yixue Ban). 26, 3, 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• KCNE3 R53H substitution in familial atrial fibrillation

  Zhang, D-F., Liang, B., Lin, J., Liu, B., Zhou, Q-S. & Yang, Y-Q., 2005, In: Chinese Medical Journal. 118, 20, p. 1735-8 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  33 Citations (Scopus)

• Left Atrial Linear Ablation of Paroxysmal Atrial Fibrillation Guided by Three-dimensional Electroanatomical System

  Zhang, D-F., Li, Y., Qi, W-G., Liang, B., Zhuang, S-W., Wang, J., Yu, L. & Bao, L-J., 2005, In: Chinese Journal of Interventional Cardiology. 13, 4, p. 219-221 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
• 2004

  Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation

  Yang, Y., Xia, M., Jin, Q., Bendahhou, S., Shi, J., Chen, Y., Liang, B., Lin, J., Liu, Y., Liu, B., Zhou, Q., Zhang, D., Wang, R., Ma, N., Su, X., Niu, K., Pei, Y., Xu, W., Chen, Z., Wan, H., & 3 othersCui, J., Barhanin, J. & Chen, Y., 2004, In: American Journal of Human Genetics. 75, 5, p. 899-905 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gain of Function Mutation 100%
  • Atrial Fibrillation 67%
  • Mutation 42%
  • KCNQ1 Potassium Channel 22%
  • Long QT Syndrome 16%
  341 Citations (Scopus)

• Progress in Cardiac Ion Channels and Anti-arrhythmic Drugs

  Lin, J., Liang, B. & Chen, Y-H., 2004, In: Tongji Daxue Xuebao (Yixue Ban). 25, 1, p. 81-83 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Recent Research and Progress in Molecular Mechanisms of Atrial Fibrillation

  Liang, B., Lin, J. & Chen, Y-H., 2004, In: Tongji Daxue Xuebao (Yixue Ban). 25, 1, p. 64-67 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Relevance of gene KCNE1 and lone atrial fibrillation

  Ni, A., Wang, R., Liang, B., Zhu, X., Lin, J., Xiang, Z., Tang, L., Wang, Y., He, L., Zhou, Q., Liu, Z. & Yang, Z., 2004, In: Shanghai Yixue. 27, 4, p. 260-261 2 p.

  Research output: Contribution to journal › Journal article › Research › peer-review