Relevance of gene KCNE1 and lone atrial fibrillation

Aizhen Ni; Rong Wang; Bo Liang; Xuxia Zhu; Jie Lin; Zuo Xiang; Lijuan Tang; Yimin Wang; Lingzhu He; Qinshu  Zhou; Zuo Liu; Zuoqing Yang

Relevance of gene KCNE1 and lone atrial fibrillation

Aizhen Ni, Rong Wang, Bo Liang, Xuxia Zhu, Jie Lin, Zuo Xiang, Lijuan Tang, Yimin Wang, Lingzhu He, Qinshu Zhou, Zuo Liu, Zuoqing Yang

Physiology of circulation, kidney and lung

Abstract

Objective: To ascertain the relevance of KCNE1 gene and lone atrial fibrillation.
Methods: 94 subjects with lone atrial fibrillation (case group) and 130 unrelated healthy controls (control group) were enrolled randomly. PCR-sequencing was performed to screen KCNE1 gene with the G116A polymorphism and then the relevance of each genotype (GA, GG or AA) of KCNE1 gene and the phenotype of lone atrial fibrillation were determined.
Results: There were no statistic differences in genotypic distributions of gene KCNE1 between case group and control group (48 vs 37, 72 vs 54 and 10 vs 3 for GA, GG and AA respectively ¿ 2= 1.568 ,P0.05).
Conclusion: KCNE1 gene is not related to lone atrial fibrillation.

Original language	Chinese
Journal	Shanghai Yixue
Volume	27
Issue number	4
Pages (from-to)	260-261
Number of pages	2
ISSN	0253-9934
Publication status	Published - 2004

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http://en.cnki.com.cn/Article_en/CJFDTotal-SHYX200404019.htm

Cite this

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title = "Relevance of gene KCNE1 and lone atrial fibrillation",

abstract = "Objective: To ascertain the relevance of KCNE1 gene and lone atrial fibrillation.Methods: 94 subjects with lone atrial fibrillation (case group) and 130 unrelated healthy controls (control group) were enrolled randomly. PCR-sequencing was performed to screen KCNE1 gene with the G116A polymorphism and then the relevance of each genotype (GA, GG or AA) of KCNE1 gene and the phenotype of lone atrial fibrillation were determined. Results: There were no statistic differences in genotypic distributions of gene KCNE1 between case group and control group (48 vs 37, 72 vs 54 and 10 vs 3 for GA, GG and AA respectively ¿ 2= 1.568 ,P0.05). Conclusion: KCNE1 gene is not related to lone atrial fibrillation.",

author = "Aizhen Ni and Rong Wang and Bo Liang and Xuxia Zhu and Jie Lin and Zuo Xiang and Lijuan Tang and Yimin Wang and Lingzhu He and Qinshu Zhou and Zuo Liu and Zuoqing Yang",

year = "2004",

language = "Kinesisk",

volume = "27",

pages = "260--261",

journal = "Shanghai Yixue",

issn = "0253-9934",

number = "4",

}

TY - JOUR

T1 - Relevance of gene KCNE1 and lone atrial fibrillation

AU - Ni, Aizhen

AU - Wang, Rong

AU - Liang, Bo

AU - Zhu, Xuxia

AU - Lin, Jie

AU - Xiang, Zuo

AU - Tang, Lijuan

AU - Wang, Yimin

AU - He, Lingzhu

AU - Zhou, Qinshu

AU - Liu, Zuo

AU - Yang, Zuoqing

PY - 2004

Y1 - 2004

N2 - Objective: To ascertain the relevance of KCNE1 gene and lone atrial fibrillation.Methods: 94 subjects with lone atrial fibrillation (case group) and 130 unrelated healthy controls (control group) were enrolled randomly. PCR-sequencing was performed to screen KCNE1 gene with the G116A polymorphism and then the relevance of each genotype (GA, GG or AA) of KCNE1 gene and the phenotype of lone atrial fibrillation were determined. Results: There were no statistic differences in genotypic distributions of gene KCNE1 between case group and control group (48 vs 37, 72 vs 54 and 10 vs 3 for GA, GG and AA respectively ¿ 2= 1.568 ,P0.05). Conclusion: KCNE1 gene is not related to lone atrial fibrillation.

AB - Objective: To ascertain the relevance of KCNE1 gene and lone atrial fibrillation.Methods: 94 subjects with lone atrial fibrillation (case group) and 130 unrelated healthy controls (control group) were enrolled randomly. PCR-sequencing was performed to screen KCNE1 gene with the G116A polymorphism and then the relevance of each genotype (GA, GG or AA) of KCNE1 gene and the phenotype of lone atrial fibrillation were determined. Results: There were no statistic differences in genotypic distributions of gene KCNE1 between case group and control group (48 vs 37, 72 vs 54 and 10 vs 3 for GA, GG and AA respectively ¿ 2= 1.568 ,P0.05). Conclusion: KCNE1 gene is not related to lone atrial fibrillation.

M3 - Tidsskriftartikel

SN - 0253-9934

VL - 27

SP - 260

EP - 261

JO - Shanghai Yixue

JF - Shanghai Yixue

IS - 4

ER -