Stefano Stella

Publikation

Publikationer pr. år 2005 2007 2014 2016 2017 2018 2019 2019

• 19 Tidsskriftartikel
• 1 Letter
• 1 Review

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2019

  High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage

  Slaymaker, I. M., Mesa, P., Kellner, M. J., Kannan, S., Brignole, E., Koob, J., Feliciano, P. R., Stella, S., Abudayyeh, O. O., Gootenberg, J. S., Strecker, J., Montoya, G. & Zhang, F., 26 mar. 2019, I: Cell Reports. 26, 13, s. 3741-3751.e5 17 s.

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  • RNA Cleavage 100%
  • CRISPR RNA 85%
  • Clustered Regularly Interspaced Short Palindromic Repeats 57%
  • RNA 46%
  • Cleavage 46%
  18 Citationer (Scopus)

  10 Downloads (Pure)

• Structure of Csx1-cOA₄ complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

  Molina, R., Stella, S., Feng, M., Sofos, N., Jauniskis, V., Pozdnyakova, I., López-Méndez, B., She, Q. & Montoya, G., 1 dec. 2019, I: Nature Communications. 10, 14 s., 4302.

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  • Clustered Regularly Interspaced Short Palindromic Repeats 100%
  • Ribonucleases 97%
  • RNA Stability 95%
  • Binding Site 61%
  • dimers 52%
  25 Citationer (Scopus)

  20 Downloads (Pure)
• 2018

  A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding

  Han, W., Stella, S., Zhang, Y., Guo, T., Sulek, K., Peng-Lundgren, L., Montoya, G. & She, Q., 2018, I: Nucleic Acids Research. 46, 19, s. 10319-10330 12 s.

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  • CRISPR-Cas Systems 100%
  • 2',5'-oligoadenylate 94%
  • Second Messenger Systems 68%
  • Ribonucleoproteins 51%
  • Clustered Regularly Interspaced Short Palindromic Repeats 48%
  26 Citationer (Scopus)

  69 Downloads (Pure)

• Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity

  Stella, S., Mesa, P., Thomsen, J., Paul, B., Alcón, P., Jensen, S. B., Saligram, B., Moses, M. E., Hatzakis, N. S. & Montoya, G., 13 dec. 2018, I: Cell. 175, 7, s. 1856-1871.e21 16 s.

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  • R-Loop Structures 100%
  • DNA Cleavage 82%
  • Catalysis 74%
  • Endonucleases 74%
  • Clustered Regularly Interspaced Short Palindromic Repeats 71%
  46 Citationer (Scopus)
• 2017

  Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA

  Alcón, P., Montoya, G. & Stella, S., 1 jul. 2017, I: Acta Crystallographica Section F: Structural Biology Communications. 73, Pt 7, s. 409-415 7 s.

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  • CRISPR RNA 100%
  • Francisella 83%
  • Guide RNA 72%
  • Endonucleases 62%
  • Clustered Regularly Interspaced Short Palindromic Repeats 60%
  6 Citationer (Scopus)

  113 Downloads (Pure)

• Class 2 CRISPR-Cas RNA-guided endonucleases: Swiss Army knives of genome editing

  Stella, S., Alcón, P. & Montoya, G., 1 nov. 2017, I: Nature Structural and Molecular Biology. 24, 11, s. 882-892 11 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Gene Editing 100%
  • Endonucleases 97%
  • Clustered Regularly Interspaced Short Palindromic Repeats 93%
  • DNA Cleavage 72%
  • RNA 56%
  30 Citationer (Scopus)

• Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage

  Stella, S., Alcón, P. & Montoya, G., 22 jun. 2017, I: Nature. 546, 7659, s. 559-563 5 s.

  Publikation: Bidrag til tidsskrift › Letter › peer review

  • endonuclease R 100%
  • R-Loop Structures 84%
  • DNA Cleavage 69%
  • DNA 29%
  • RNA 20%
  69 Citationer (Scopus)
• 2016

  DNA sequence determinants controlling affinity, stability and shape of DNA complexes bound by the nucleoid protein Fis

  Hancock, S. P., Stella, S., Cascio, D. & Johnson, R. C., 2016, I: PLOS ONE. 11, 3, 24 s., e0150189.

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  • DNA sequences 100%
  • DNA Sequence 98%
  • Affine transformation 91%
  • Protein 84%
  • DNA 84%
  20 Citationer (Scopus)

  289 Downloads (Pure)

• The genome editing revolution: A CRISPR-Cas TALE off-target story

  Stella, S. & Montoya, G., 1 jul. 2016, I: BioEssays. 38, S1, s. S4-S13

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  • CRISPR-Associated Proteins 100%
  • Gene Editing 68%
  • Clustered Regularly Interspaced Short Palindromic Repeats 64%
  • DNA 31%
  • Transcription Activator-Like Effectors 24%
  31 Citationer (Scopus)
• 2015

  Visualizing phosphodiester-bond hydrolysis by an endonuclease

  Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M. J., Orozco, M., Prieto, J. & Montoya, G., jan. 2015, I: Nature Structural and Molecular Biology. 22, 1, s. 65-72 8 s.

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  • Endonucleases 100%
  • Hydrolysis 77%
  • Metals 72%
  • endodeoxyribonuclease I-Dmo I 50%
  • Desulfurococcaceae 40%
  25 Citationer (Scopus)
• 2014

  BuD, a helix-loop-helix DNA-binding domain for genome modification

  Stella, S., Molina, R., López-Méndez, B., Juillerat, A., Bertonati, C., Daboussi, F., Campos-Olivas, R., Duchateau, P. & Montoya, G., 1 jan. 2014, I: Acta Crystallographica Section D: Biological Crystallography. 70, 7, s. 2042-2052 11 s.

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  • Genome 100%
  • DNA 82%
  • Gene Targeting 49%
  • Helix-Loop-Helix Motifs 33%
  • Synthetic Biology 29%
  13 Citationer (Scopus)

• Comprehensive analysis of the specificity of transcription activator-like effector nucleases

  Juillerat, A., Dubois, G., Valton, J., Thomas, S., Stella, S., Maréchal, A., Langevin, S., Benomari, N., Bertonati, C., Silva, G. H., Daboussi, F., Epinat, J-C., Montoya, G., Duclert, A. & Duchateau, P., apr. 2014, I: Nucleic Acids Research. 42, 8, s. 5390-402 13 s.

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  • Transcription Activator-Like Effector Nucleases 100%
  • Oligonucleotide Array Sequence Analysis 34%
  • DNA Cleavage 22%
  • Deoxyribonucleases 20%
  • DNA 18%
  59 Citationer (Scopus)

• Expression, purification, crystallization and preliminary X-ray diffraction analysis of the novel modular DNA-binding protein BurrH in its apo form and in complex with its target DNA

  Stella, S., Molina, R., Bertonatti, C., Juillerrat, A. & Montoya, G., 1 jan. 2014, I: Acta Crystallographica Section F:Structural Biology Communications. 70, 1, s. 87-91 5 s.

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  • Crystallization 100%
  • X-Ray Diffraction 98%
  • purification 94%
  • DNA-Binding Proteins 92%
  • deoxyribonucleic acid 75%
  8 Citationer (Scopus)

• Purification, characterization and crystallization of the human 80S ribosome

  Khatter, H., Myasnikov, A. G., Mastio, L., Billas, I. M. L., Birck, C., Stella, S. & Klaholz, B. P., 1 jan. 2014, I: Nucleic Acids Research. 42, 6

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  • Crystallization 100%
  • Ribosomes 86%
  • Single Molecule Imaging 18%
  • Cryoelectron Microscopy 18%
  • Ultracentrifugation 16%
  27 Citationer (Scopus)
• 2013

  Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism

  Stella, S., Molina, R., Yefimenko, I., Prieto, J., Silva, G., Bertonati, C., Juillerat, A., Duchateau, P. & Montoya, G., 1 sep. 2013, I: Acta Crystallographica Section D: Biological Crystallography. 69, 9, s. 1707-1716 10 s.

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  • Thymine 100%
  • DNA 41%
  • Transcription Activator-Like Effectors 25%
  • Nucleotides 23%
  • Dipeptides 19%
  25 Citationer (Scopus)
• 2012

  Non-specific protein-DNA interactions control I-CreI target binding and cleavage

  Molina, R., Redondo, P., Stella, S., Marenchino, M., D'Abramo, M., Gervasio, F. L., Charles Epinat, J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, G., 1 aug. 2012, I: Nucleic Acids Research. 40, 14, s. 6936-6945 10 s.

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  • endodeoxyribonuclease CreI 100%
  • DNA 27%
  • Proteins 18%
  • Endonucleases 16%
  • Enzymes 11%
  20 Citationer (Scopus)
• 2010

  The shape of the DNA minor groove directs binding by the DNA-bending protein Fis

  Stella, S., Cascio, D. & Johnson, R. C., 15 apr. 2010, I: Genes and Development. 24, 8, s. 814-826 13 s.

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  • DNA-Binding Proteins 100%
  • DNA 49%
  • Helix-Turn-Helix Motifs 29%
  • Base Pairing 9%
  • Computer Simulation 8%
  118 Citationer (Scopus)
• 2007

  High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes

  Lang, B., Blot, N., Bouffartigues, E., Buckle, M., Geertz, M., Gualerzi, C. O., Mavathur, R., Muskhelishvili, G., Pon, C. L., Rimsky, S., Stella, S., Babu, M. M. & Travers, A., 1 sep. 2007, I: Nucleic Acids Research. 35, 18, s. 6330-6337 8 s.

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  • Binding Sites 100%
  • Genome 88%
  • DNA 72%
  • AT Rich Sequence 66%
  • Bacterial Chromosomes 65%
  183 Citationer (Scopus)

• The -35 sequence location and the Fis-sigma factor interface determine σs selectivity of the proP (P2) promoter in Escherichia coli

  Typas, A., Stella, S., Johnson, R. C. & Hengge, R., 1 feb. 2007, I: Molecular Microbiology. 63, 3, s. 780-796 17 s.

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  • Sigma Factor 100%
  • stachydrine 68%
  • Escherichia coli 52%
  • Betaine 52%
  • DNA-Directed RNA Polymerases 41%
  19 Citationer (Scopus)
• 2006

  Environmental control of the in vivo oligomerization of nucleoid protein H-NS

  Stella, S., Falconi, M., Lammi, M., Gualerzi, C. O. & Pon, C. L., 13 jan. 2006, I: Journal of Molecular Biology. 355, 2, s. 169-174 6 s.

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  • Dimerization 100%
  • Temperature 95%
  • Protein Multimerization 67%
  • Cold-Shock Response 58%
  • Osmotic Pressure 53%
  40 Citationer (Scopus)
• 2005

  Nature and mechanism of the in vivo oligomerization of nucleoid protein H-NS

  Stella, S., Spurio, R., Falconi, M., Pon, C. L. & Gualerzi, C. O., 17 aug. 2005, I: EMBO Journal. 24, 16, s. 2896-2905 10 s.

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  • Oligomerization 100%
  • Histones 91%
  • Protein 40%
  • Proteins 35%
  • Tetramer 21%
  46 Citationer (Scopus)