Stefano Stella

2019

High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage

Slaymaker, I. M., Mesa, P., Kellner, M. J., Kannan, S., Brignole, E., Koob, J., Feliciano, P. R., Stella, S., Abudayyeh, O. O., Gootenberg, J. S., Strecker, J., Montoya, G. & Zhang, F., 26 Mar 2019, In: Cell Reports. 26, 13, p. 3741-3751.e5 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

10 Downloads (Pure)

Structure of Csx1-cOA₄ complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

Molina, R., Stella, S., Feng, M., Sofos, N., Jauniskis, V., Pozdnyakova, I., López-Méndez, B., She, Q. & Montoya, G., 1 Dec 2019, In: Nature Communications. 10, 14 p., 4302.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

20 Downloads (Pure)

2018

A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding

Han, W., Stella, S., Zhang, Y., Guo, T., Sulek, K., Peng-Lundgren, L., Montoya, G. & She, Q., 2018, In: Nucleic Acids Research. 46, 19, p. 10319-10330 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

69 Downloads (Pure)

Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity

Stella, S., Mesa, P., Thomsen, J., Paul, B., Alcón, P., Jensen, S. B., Saligram, B., Moses, M. E., Hatzakis, N. S. & Montoya, G., 13 Dec 2018, In: Cell. 175, 7, p. 1856-1871.e21 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

46 Citations (Scopus)

2017

Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA

Alcón, P., Montoya, G. & Stella, S., 1 Jul 2017, In: Acta Crystallographica Section F: Structural Biology Communications. 73, Pt 7, p. 409-415 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

113 Downloads (Pure)

Class 2 CRISPR-Cas RNA-guided endonucleases: Swiss Army knives of genome editing

Stella, S., Alcón, P. & Montoya, G., 1 Nov 2017, In: Nature Structural and Molecular Biology. 24, 11, p. 882-892 11 p.

Research output: Contribution to journal › Review › peer-review

30 Citations (Scopus)

Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage

Stella, S., Alcón, P. & Montoya, G., 22 Jun 2017, In: Nature. 546, 7659, p. 559-563 5 p.

Research output: Contribution to journal › Letter › peer-review

69 Citations (Scopus)

2016

DNA sequence determinants controlling affinity, stability and shape of DNA complexes bound by the nucleoid protein Fis

Hancock, S. P., Stella, S., Cascio, D. & Johnson, R. C., 2016, In: PLOS ONE. 11, 3, 24 p., e0150189.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

289 Downloads (Pure)

The genome editing revolution: A CRISPR-Cas TALE off-target story

Stella, S. & Montoya, G., 1 Jul 2016, In: BioEssays. 38, S1, p. S4-S13

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

2015

Visualizing phosphodiester-bond hydrolysis by an endonuclease

Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M. J., Orozco, M., Prieto, J. & Montoya, G., Jan 2015, In: Nature Structural and Molecular Biology. 22, 1, p. 65-72 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

2014

BuD, a helix-loop-helix DNA-binding domain for genome modification

Stella, S., Molina, R., López-Méndez, B., Juillerat, A., Bertonati, C., Daboussi, F., Campos-Olivas, R., Duchateau, P. & Montoya, G., 1 Jan 2014, In: Acta Crystallographica Section D: Biological Crystallography. 70, 7, p. 2042-2052 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Comprehensive analysis of the specificity of transcription activator-like effector nucleases

Juillerat, A., Dubois, G., Valton, J., Thomas, S., Stella, S., Maréchal, A., Langevin, S., Benomari, N., Bertonati, C., Silva, G. H., Daboussi, F., Epinat, J-C., Montoya, G., Duclert, A. & Duchateau, P., Apr 2014, In: Nucleic Acids Research. 42, 8, p. 5390-402 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

59 Citations (Scopus)

Expression, purification, crystallization and preliminary X-ray diffraction analysis of the novel modular DNA-binding protein BurrH in its apo form and in complex with its target DNA

Stella, S., Molina, R., Bertonatti, C., Juillerrat, A. & Montoya, G., 1 Jan 2014, In: Acta Crystallographica Section F:Structural Biology Communications. 70, 1, p. 87-91 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Purification, characterization and crystallization of the human 80S ribosome

Khatter, H., Myasnikov, A. G., Mastio, L., Billas, I. M. L., Birck, C., Stella, S. & Klaholz, B. P., 1 Jan 2014, In: Nucleic Acids Research. 42, 6

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

2013

Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism

Stella, S., Molina, R., Yefimenko, I., Prieto, J., Silva, G., Bertonati, C., Juillerat, A., Duchateau, P. & Montoya, G., 1 Sept 2013, In: Acta Crystallographica Section D: Biological Crystallography. 69, 9, p. 1707-1716 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

2012

Non-specific protein-DNA interactions control I-CreI target binding and cleavage

Molina, R., Redondo, P., Stella, S., Marenchino, M., D'Abramo, M., Gervasio, F. L., Charles Epinat, J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, G., 1 Aug 2012, In: Nucleic Acids Research. 40, 14, p. 6936-6945 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

2010

The shape of the DNA minor groove directs binding by the DNA-bending protein Fis

Stella, S., Cascio, D. & Johnson, R. C., 15 Apr 2010, In: Genes and Development. 24, 8, p. 814-826 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

118 Citations (Scopus)

2007

High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes

Lang, B., Blot, N., Bouffartigues, E., Buckle, M., Geertz, M., Gualerzi, C. O., Mavathur, R., Muskhelishvili, G., Pon, C. L., Rimsky, S., Stella, S., Babu, M. M. & Travers, A., 1 Sept 2007, In: Nucleic Acids Research. 35, 18, p. 6330-6337 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

183 Citations (Scopus)

The -35 sequence location and the Fis-sigma factor interface determine σs selectivity of the proP (P2) promoter in Escherichia coli

Typas, A., Stella, S., Johnson, R. C. & Hengge, R., 1 Feb 2007, In: Molecular Microbiology. 63, 3, p. 780-796 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

2006

Environmental control of the in vivo oligomerization of nucleoid protein H-NS

Stella, S., Falconi, M., Lammi, M., Gualerzi, C. O. & Pon, C. L., 13 Jan 2006, In: Journal of Molecular Biology. 355, 2, p. 169-174 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

2005

Nature and mechanism of the in vivo oligomerization of nucleoid protein H-NS

Stella, S., Spurio, R., Falconi, M., Pon, C. L. & Gualerzi, C. O., 17 Aug 2005, In: EMBO Journal. 24, 16, p. 2896-2905 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

46 Citations (Scopus)

Stefano Stella

Research output

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