Povl Krogsgaard-Larsen

Publikation

Publikationer pr. år 1987 1999 2000 2001 2002 2003 2005 2017

• 128 Tidsskriftartikel
• 28 Bidrag til bog/antologi
• 3 Bog
• 3 Konferenceabstrakt i tidsskrift
• 3 Mere
  • 1 Kommentar/debat
  • 1 Konferenceartikel
  • 1 Review

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2017

  Astrocytic GABA Transporters: Pharmacological Properties and Targets for Antiepileptic Drugs

  Schousboe, A., Wellendorph, P., Frølund, B., Clausen, R. P. & Krogsgaard-Larsen, P., 2017, Glial Amino Acid Transporters. Springer, Bind 16. s. 283-296 14 s. (Advances in Neurobiology).

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Formidling

  • GABA Plasma Membrane Transport Proteins 100%
  • gamma-Aminobutyric Acid 62%
  • Anticonvulsants 61%
  • Pharmacology 43%
  • Tiagabine 20%
  13 Citationer (Scopus)
• 2015

  GABAA receptor partial agonists and antagonists: structure, binding mode, and pharmacology

  Krall, J., Balle, T., Krogsgaard-Larsen, N., Sørensen, T. E., Krogsgaard-Larsen, P., Kristiansen, U. & Frølund, B., 2015, Diversity and functions of GABA receptors: A tribute to Hanns Möhler, Part A. Bind 72. s. 201-27 27 s. (Advances in Pharmacology).

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

  • GABA-A Receptor Agonists 100%
  • GABA-A Receptor Antagonists 96%
  • GABA-A Receptors 76%
  • Pharmacology 47%
  • Binding Sites 18%
  24 Citationer (Scopus)
• 2014

  Probing the orthosteric binding site of GABAA receptors with heterocyclic GABA carboxylic acid bioisosteres

  Petersen, J. G., Bergmann, R., Krogsgaard-Larsen, P., Balle, T. & Frølund, B., jun. 2014, I: Neurochemical Research. 39, s. 1005-1015

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Carboxylic Acids 100%
  • GABA-A Receptors 83%
  • gamma-Aminobutyric Acid 74%
  • Carboxylic Acid 60%
  • Binding Sites 60%
  15 Citationer (Scopus)

• Probing α4βδ GABAA Receptor Heterogeneity: Differential Regional Effects of a Functionally Selective α4β1δ/α4β3δ Receptor Agonist on Tonic and Phasic Inhibition in Rat Brain

  Hoestgaard-Jensen, K., Dalby, N. O., Krall, J., Hammer, H., Krogsgaard-Larsen, P., Frølund, B. & Jensen, A. A., 3 dec. 2014, I: Journal of Neuroscience. 34, 49, s. 16256-16272 17 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 4,5,6,7-tetrahydroisoxazolo(3,4c)pyridin-5-ol 100%
  • GABA-A Receptors 44%
  • Brain 20%
  • Neurons 14%
  • Dentate Gyrus 12%
  20 Citationer (Scopus)
• 2013

  Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties

  Jensen, A. A., Plath, N., Pedersen, M. H. F., Isberg, V., Krall, J., Wellendorph, P., Stensbøl, T. B., Gloriam, D. E., Krogsgaard-Larsen, P. & Frølund, B., 14 feb. 2013, I: Journal of Medicinal Chemistry. 56, 3, s. 1211-27 17 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 5,6,7,8-tetrahydro-4H-isoxazolo(4,5-d)azepin-3-ol 100%
  • Glycine Receptor Antagonist 82%
  • Serotonin 2C Antagonist 79%
  • Cognitive Enhancer 72%
  • Receptor, Serotonin, 5-HT2C 59%
  43 Citationer (Scopus)

• Selective mGAT2 (BGT-1) GABA Uptake Inhibitor: Design, synthesis and pharmacological characterization

  Vogensen, S. B., Jørgensen, L., Madsen, K. K., Borkar, N. N., Wellendorph, P., Skovgaard-Petersen, J., Schousboe, A., White, H. S., Krogsgaard-Larsen, P. & Clausen, R. P., 14 mar. 2013, I: Journal of Medicinal Chemistry. 56, 5, s. 2160-2164 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • GABA Uptake Inhibitor 100%
  • GABA Uptake Inhibitors 97%
  • GABA Plasma Membrane Transport Proteins 44%
  • Amino Acids 40%
  • Pharmacology 38%
  33 Citationer (Scopus)

• The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors

  Hoestgaard-Jensen, K., O'Connor, R. M., Dalby, N. O., Simonsen, C., Finger, B. C., Golubeva, A., Hammer, H., Bergmann, M. L., Kristiansen, U., Krogsgaard-Larsen, P., Bräuner-Osborne, H., Ebert, B., Frølund, B., Cryan, J. F. & Jensen, A. A., okt. 2013, I: British Journal of Pharmacology. 170, 4, s. 919-32 14 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 5-(4-piperidyl)-3-isothiazolol 100%
  • Neurotransmitter Receptor 50%
  • GABA-A Receptors 44%
  • Ligands 29%
  • gamma-Aminobutyric Acid 9%
  13 Citationer (Scopus)
• 2011

  Scientific social responsibility: a call to arms

  Krogsgaard-Larsen, P., Thostrup, P. & Besenbacher, F., 11 nov. 2011, I: Angewandte Chemie International Edition. 50, 46, s. 10738-10740

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning

  10 Citationer (Scopus)

• Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol

  Madsen, K. K., Ebert, B., Clausen, R. P., Krogsgaard-Larsen, P., Schousboe, A. & White, H. S., 1 jul. 2011, I: Journal of Pharmacology and Experimental Therapeutics. 338, 1, s. 214-219

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • EF1502 100%
  • gaboxadol 71%
  • Tiagabine 68%
  • GABA Plasma Membrane Transport Proteins 68%
  • GABA-A Receptor Agonists 62%
  38 Citationer (Scopus)
• 2010

  Acetylcholine

  Jensen, A. A. & Krogsgaard-Larsen, P., 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (red.). 4 udg. Boca Raton: CRC Press, s. 263-281

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Undervisning

• Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid

  Frydenvang, K. A., Pickering, D. S., Greenwood, J. R., Krogsgaard-Larsen, N., Brehm, L., Nielsen, B., Vogensen, S. B., Hald, H., Kastrup, J. S., Krogsgaard-Larsen, P. & Clausen, R. P., 9 dec. 2010, I: Journal of Medicinal Chemistry. 53, 23, s. 8354-8361

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glutamate Receptor Agonist 100%
  • Ibotenic Acid 94%
  • 3-hydroxy-4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridine-7-carboxylic acid 91%
  • Excitatory Amino Acid Agonists 73%
  • AMPA Receptors 63%
  16 Citationer (Scopus)

• Introduction to drug design and discovery

  Krogsgaard-Larsen, P. & Bunch, L., 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (red.). 4 udg. Boca Raton: CRC Press, s. 1-13

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Undervisning

• Textbook of drug design and discovery

  Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U., 2010, 4 udg. Boca Raton: CRC Press. 460 s.

  Publikation: Bog/antologi/afhandling/rapport › Bog › Undervisning
• 2009

  Detecting protein-protein interactions in living cells: development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction

  Gottschalk, M., Bach, A., Hansen, J. L., Krogsgaard-Larsen, P., Kristensen, A. S. & Strømgaard, K., 2009, I: Neurochemical Research. 34, 10, s. 1729-1737

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Energy Transfer 100%
  • Bioluminescence 91%
  • N-Methyl-D-Aspartate Receptors 76%
  • Fluorescence Resonance Energy Transfer 74%
  • PDZ Domains 52%
  7 Citationer (Scopus)

• Subtype selective kainic acid receptor agonists: discovery and approaches to rational design

  Bunch, L. & Krogsgaard-Larsen, P., 2009, I: Medicinal Research Reviews. 29, 1, s. 3-28

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Kainic Acid Receptor Agonist 100%
  • Kainic Acid 74%
  • Kainic Acid Receptors 66%
  • Glutamic Acid 51%
  • Glutamate Receptors 35%
  44 Citationer (Scopus)

• Synaptic and extrasynaptic GABA transporters as targets for anti-epileptic drugs

  Madsen, K. K., Clausen, R. P., Larsson, O. M., Krogsgaard-Larsen, P., Schousboe, A. & White, H. S., 2009, I: Journal of Neurochemistry. 109, Suppl. 1, s. 139-44

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • EF1502 100%
  • Tiagabine 80%
  • GABA Plasma Membrane Transport Proteins 68%
  • Anticonvulsant 51%
  • 1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)-3-piperidinecarboxylic acid 37%
  97 Citationer (Scopus)

• Synergies within the natural sciences at the University of Copenhagen: an interfaculty evaluation of barriers and opportunities to improve the quality of infrastructure, research and education

  Krogsgaard-Larsen, P., Møller, B. L., Larsen, E. H., Vestergaard, B., Lunde, C., Stæhr, P. A. & Andersen, J. (red.), 2009, Faculty of Life Sciences: Museum Tusculanum. 43 s.

  Publikation: Bog/antologi/afhandling/rapport › Bog › Forskning

• The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

  Clausen, R. P., Naur, P., Kristensen, A. S., Greenwood, J. R., Strange, M., Bräuner-Osborne, H., Jensen, A. A., Nielsen, A. S. T., Geneser, U., Ringgaard, L. M., Nielsen, B., Pickering, D. S., Brehm, L., Gajhede, M., Krogsgaard-Larsen, P. & Kastrup, J. S., 2009, I: Journal of Medicinal Chemistry. 52, 15, s. 4911-4922

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Ionotropic Glutamate Receptors 100%
  • propionic acid 98%
  • Glutamate Receptors 82%
  • Propionic Acid 80%
  • Agonist 71%
  20 Citationer (Scopus)
• 2008

  Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC)

  Smith, M. D., Saunders, G. W., Clausen, R. P., Frølund, B. F., Krogsgaard-Larsen, P., Larsson, O. M., Schousboe, A., Wilcox, K. S. & White, H. S., 2008, I: Epilepsy Research. 79, 1, s. 6-13

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  22 Citationer (Scopus)

• Ligands for the GABA recognition site at the GABAA receptor: Structure-activity studies

  Frølund, B. F., Kristiansen, U., Krogsgaard-Larsen, P. & Liljefors, T., 2008, Chemistry and molecular aspects of drug design and action. Rekka, E. A. & Kourounakis, P. N. (red.). Boca Raton, Fl: CRC Press, s. 139-147

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning
• 2007

  4-aryl-5-(4-piperidyl)-3-isoxazolol GABA_A antagonists: synthesis, pharmacology, and structure-activity relationships

  Frølund, B. F., Jensen, L. S., Storustovu, S. I., Stensbøl, T. B., Ebert, B., Kehler, J., Krogsgaard-Larsen, P. & Liljefors, T., 2007, I: Journal of Medicinal Chemistry. 50, 8, s. 1988-1992

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  26 Citationer (Scopus)

• 5-substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel ¿-aminobutyric acid_C receptor agonists

  Madsen, C., Jensen, A. A., Liljefors, T., Kristiansen, U., Nielsen, B., Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, P. & Frølund, B. F., 2007, I: Journal of Medicinal Chemistry. 50, 17, s. 4147-4161

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  42 Citationer (Scopus)

• 5-Substituted imidazole-4-acetic acid analogues: Synthesis, modeling, and pharmacological characterization of a series of novel γ-aminobutyric acidC receptor agonists

  Madsen, C., Jensen, A. A., Liljefors, T., Kristiansen, U., Nielsen, B., Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, P. & Frølund, B., 2007, I: Journal of Medicinal Chemistry. 50, s. 4147-4161

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  42 Citationer (Scopus)

• A tetrazolyl-substituted subtype-selective AMPA receptor agonist

  Vogensen, S. B., Frydenvang, K. A., Greenwood, J. R., Postorino, G., Nielsen, B., Pickering, D. S., Ebert, B., Bølcho, U., Egebjerg, J., Gajhede, M., Kastrup, J. S. J., Johansen, T. N., Clausen, R. P. & Krogsgaard-Larsen, P., 2007, I: Journal of Medicinal Chemistry. 50, 10, s. 2408-2414

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  25 Citationer (Scopus)

• Functional and pharmacological aspects of GABA transporters

  Madsen, K., White, H. S., Clausen, R. P., Frølund, B. F., Larsson, O. M., Krogsgaard-Larsen, P. & Schousboe, A., 2007, Handbook of nerochemistry and molecular neurobiology: Neural membranes and transport. Lajtha, A. & Reith, M. E. A. (red.). 3rd. udg. Berlin: Springer, Bind 3. s. 285-304

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning

  22 Citationer (Scopus)

• Novel 5-substituted 1-pyrazolol analogues of ibotenic acid: synthesis and pharmacology at glutamate receptors

  Jørgensen, C. G., Bräuner-Osborne, H., Nielsen, B., Kehler, J., Clausen, R. P., Krogsgaard-Larsen, P. & Madsen, U., 2007, I: Bioorganic & Medicinal Chemistry. 15, 10, s. 3524-3538

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  12 Citationer (Scopus)

• Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ibotenic acid

  Jørgensen, C. G., Clausen, R. P., Hansen, K. B., Bräuner-Osborne, H., Nielsen, B., Metzler, B., Kehler, J., Krogsgaard-Larsen, P. & Madsen, U., 2007, I: Organic & Biomolecular Chemistry. 5, 3, s. 463-471

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  12 Citationer (Scopus)
• 2006

  A novel selective γ-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS

  Frølund, B., Clausen, R. P., Larsson, O. M., Schousboe, A., Krogsgaard-Larsen, P. & White, H. S., 2006, I: Neurochemistry International. 48, s. 637–642

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  35 Citationer (Scopus)

• Functional and Pharmacological Aspects of GABA Transporters

  Madsen, K., White, S. H., Clausen, R. P., Larsson, O. M., Frølund, B., Krogsgaard-Larsen, P. & Schousboe, A., 2006, Handbook of Neurochemistry and Molecular neurobiology. s. 1-17

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

• GABA_A Agonists and Partial Agonists: THIP (Gaboxadol) as a Non-Opioid Analgesic and a Novel Type of Hypnotic

  Krogsgaard-Larsen, P., Frølund, B., Liljefors, T. & Ebert, B., 2006, GABA. Enna, S. (red.). s. 53–71 (Advances in Pharmacology).

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

• Potent 4-Arylalkyl-Substituted 3-Isothiazolol GABAA Competitive/Noncompetitive Antagonists: Synthesis and Pharmacology

  Krehan, D., i Storustovu, S., Liljefors, T., Ebert, B., Nielsen, B., Krogsgaard-Larsen, P. & Frølund, B., 2006, I: Journal of Medicinal Chemistry. 49, s. 1388–1396

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  24 Citationer (Scopus)

• Structure-Activity Relationship and Pharmacology of γ-Aminobutyric Acid (GABA) Transport Inhibitors

  Clausen, R. P., Madsen, K., Larsson, O. M., Frølund, B., Krogsgaard-Larsen, P. & Schousboe, A., 1 dec. 2006, GABA. Enna, S. J. (red.). s. 265-284 20 s. (Advances in Pharmacology, Bind 54).

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

  36 Citationer (Scopus)

• Structure–Activity Relationship and Pharmacology of γ‐Aminobutyric Acid Transport Inhibitor

  Clausen, R. P., Madsen, K., Larsson, O. M., Frølund, B., Krogsgaard-Larsen, P. & Schousboe, A., 2006, GABA. Enna, S. (red.). Bind 54. s. 265–284 (Advances in Pharmacology).

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

• Structure-Activity Relationships of Selective GABA Uptake Inhibitors

  Høg, S., Greenwood, J., Madsen, K. B., Larsson, O. M., Frølund, B., Schousboe, A., Krogsgaard-Larsen, P. & Clausen, R. P., 2006, I: Current Topics in Medicinal Chemistry. 6, 17, s. 1861–1882

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  58 Citationer (Scopus)
• 2005

  Convergent synthesis and pharmacology of substituted tetrazolyl-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid analogues

  Vogensen, SB., Clausen, R. P., Greenwood, JR., Johansen, T. N., Pickering, DS., Nielsen, B., Ebert, B. & Krogsgaard-Larsen, P., 5 maj 2005, I: Journal of Medicinal Chemistry. 48, 9, s. 3438-3442

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  23 Citationer (Scopus)

• Design, synthesis, and characterisation of selective GABA transport inhibitors

  Clausen, R. P., Moltzen, EK., Perregaard, J., Lenz, SM., Sanchez, S., Frolund, B., Bolvig, T., Sarup, A., Larsson, OM., White, HS., Schousboe, A. & Krogsgaard-Larsen, P., aug. 2005, I: Journal of Neurochemistry. 94, s. 150-150

  Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning

  8 Citationer (Scopus)

• First Demonstration of a Functional Role for CNS Betaine/GABA Transporter (mGAT2) Based on Synergistic Anticonvulsant Action Among Inhibitors of mGAT1 and mGAT2

  White, S., Watson, W. P., Hansen, S. L., Slough, S., Perregård, J., Sarup, A., Bolvig, T., Petersen, G., Larsson, O. M., Clausen, R. P., Frølund, B., Falch, E., Krogsgaard-Larsen, P. & Schousboe, A., 2005, I: The Journal of Pharmacology and Experimental Therapeutics. 312, s. 866–874

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• GABA and Glutamate Receptor Ligands and Therapeutic Potential in CNS Disorders

  Madsen, U., Greenwood, J., Johansen, T. N., Krogsgaard-Larsen, P., Liljefors, T., Nielsen, M. & Frølund, B., 2005, Drug Discovery Handbook. Wiley, s. 797–907

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

• Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations

  Jensen, A. A., Frølund, B., Liljefors, T. & Krogsgaard-Larsen, P., 2005, I: Journal of Medicinal Chemistry. 48, 15, s. 4705-45 41 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  456 Citationer (Scopus)

• Potent 4-aryl- or 4-arylalkyl-substituted 3-isoxazolol GABA_A antagonists: Synthesis, pharmacology, and molecular modeling

  Frølund, B., Jensen, L. S., Guandalini, L., Canillo, C., Vestergaard, H. T., Kristiansen, U., Nielsen, B., Stensbøl, T. B., Madsen, C., Krogsgaard-Larsen, P. & Liljefors, T., 27 jan. 2005, I: Journal of Medicinal Chemistry. 48, 2, s. 427-439 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 4-PIOL 100%
  • 4 Aminobutyric Acid A Receptor Blocking Agent 88%
  • 5-(4-piperidyl)isoxazol-3-ol 71%
  • GABA-A Receptor Antagonists 64%
  • GABA-A Receptors 51%
  37 Citationer (Scopus)

• Potent 4-Aryl- or 4-Arylalkyl-Substituted 3-Isoxazolol GABA_A Antagonists: Synthesis, Pharmacology, and Molecular Modeling

  Frølund, B., Jensen, L. S., Guandalini, L., Canillo, C., Vestergaard, H. T., Kristiansen, U., Nielsen, B., Stensbøl, T. B., Madsen, C., Krogsgaard-Larsen, P. & Liljefors, T., 2005, I: Journal of Medicinal Chemistry. 48, s. 427–439

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Selective inhibitors of GABA uptake: synthesis and molecular pharmacology of 4-N-methylamino- 4,5,6,7-tetrahydrobenzo[d]isoxazol-3-ol analogues

  Clausen, R. P., Moltzen, E. K., Perregaard, J., Lenz, S., Sanchez, C., Falch, E., Frølund, B., Bolvig, T., Sarup, A., Larsson, O. M., Schousboe, A. & Krogsgaard-Larsen, P., 2005, I: Bioorganic & Medicinal Chemistry. 13, s. 895–908

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  81 Citationer (Scopus)

• Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: synthesis, modelling and molecular pharmacology

  Frølund, B., Greenwood, J. R., Holm, M. M., Egebjerg, J., Madsen, U., Nielsen, B., Bräuner-Osborne, H., Stensbøl, T. B. & Krogsgaard-Larsen, P., 15 sep. 2005, I: Bioorganic & Medicinal Chemistry. 13, 18, s. 5391-8

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Ionotropic Receptor Antagonist 100%
  • Kainic Acid 73%
  • Isoxazoles 69%
  • Kainic Acid Receptors 65%
  • Ionotropic Glutamate Receptors 64%
  12 Citationer (Scopus)
• 2004

  Activation on single heteromeric GABA_A receptor Ion channels by full and partial agonists

  Mortensen, M., Kristiansen, U., Ebert, B., Frølund, B., Krogsgaard-Larsen, P. & Smart, T., 2004, I: Journal of Physiology. s. 393–417

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• A stereochemical anomaly: the cyclised (R)-AMPA analogue (R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid [(R)-5-HPCA] resembles (S)-AMPA at glutamate receptors

  Vogensen, SB., Greenwood, JR., Varming, A. R., Brehm, L., Pickering, DS., Nielsen, B., Liljefors, T., Clausen, R. P., Johansen, T. N. & Krogsgaard-Larsen, P., 2004, I: Organic & Biomolecular Chemistry. 2, 2, s. 206-213

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  21 Citationer (Scopus)

• Carbamoylcholine homologs: synthesis and pharmacology at nicotinic acetylcholine receptors

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  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Carbachol 100%
  • Nicotinic Receptors 98%
  • N,N-dimethylcarbamate 71%
  • Pharmacology 59%
  • X Ray Crystallography 40%
  8 Citationer (Scopus)

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  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

• GABA_A agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of Hypnotic

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• Ibotenic acid and thioibotenic acid: a remarkable difference in activity at group III metabotropic glutamate receptors

  Hermit, M. B., Greenwood, J. R., Nielsen, B., Bunch, L., Jørgensen, C. G., Vestergaard, H. T., Stensbøl, T. B., Sanchez, C., Krogsgaard-Larsen, P., Madsen, U. & Bräuner-Osborne, H., 23 feb. 2004, I: European Journal of Pharmacology. 486, 3, s. 241-50

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  • Ibotenic Acid 100%
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  • Pharmacology 33%
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  45 Citationer (Scopus)

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  • alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid 100%
  • Glutamic Acid 85%
  • Acids 72%
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  9 Citationer (Scopus)