Abstract
Peptide nucleic acids (PNAs) are DNA mimics with a peptide backbone. PNAs are being intensely investigated owing to a potential as gene-targeted drugs. A PNA (H-GTAGATCACT-NH2)-DNA (5'-AGTGATCTAC-3') complex has been crystallized in a tetragonal space group P4(1)22 with cell dimensions a = b = 79.8, c = 99.9 angstrum. The crystals diffract to about 5 angstrum resolution.
| Original language | English |
|---|---|
| Journal | FEBS Letters |
| Volume | 363 |
| Issue number | 1-2 |
| Pages (from-to) | 115-7 |
| Number of pages | 3 |
| ISSN | 0014-5793 |
| Publication status | Published - 17 Apr 1995 |
Keywords
- Base Sequence
- Crystallization
- Crystallography, X-Ray
- DNA/chemistry
- Molecular Sequence Data
- Oligodeoxyribonucleotides/chemistry