Thomas van Overeem Hansen

2018

MicroRNA dysregulation in adenoid cystic carcinoma of the salivary gland in relation to prognosis and gene fusion status: a cohort study

Andreasen, S., Tan, Q., Agander, T. K., Hansen, T. V. O., Steiner, P., Bjørndal, K., Høgdall, E., Larsen, S. R., Erentaite, D., Olsen, C. H., Ulhøi, B. P., Heegaard, S., Wessel, I. & Homøe, P., Sept 2018, In: Virchows Archiv. 473, 3, p. 329-340

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

2016

Validation study of HPV DNA detection from stained FNA smears by polymerase chain reaction: Improving the diagnostic workup of patients with a tumor on the neck

Channir, H. I., Larsen, C. G., Ahlborn, L. B., Hansen, T. V. O., Gerds, T. A., Charabi, B. W., Vainer, B., von Buchwald, C., Lajer, C. B. & Kiss, K., 1 Nov 2016, In: Cancer Cytopathology. 124, 11, p. 820-827 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

2014

IMP3 RNP safe houses prevent miRNA-directed HMGA2 mRNA decay in cancer and development

Jønson, L., Christiansen, J., Hansen, T. V. O., Vikeså, J., Yamamoto, Y. & Nielsen, F. C., 24 Apr 2014, In: Cell Reports. 7, 2, p. 539-551 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

49 Citations (Scopus)

1360 Downloads (Pure)

The genetic prehistory of the New World Arctic

Raghavan, M., DeGiorgio, M., Albrechtsen, A., Moltke, I., Skoglund, P., Korneliussen, T. S., Grønnow, B., Appelt, M., Gulløv, H. C., Friesen, T. M., Fitzhugh, W., Malmström, H. S., Rasmussen, S., Olsen, J., Melchior, L. C., Fuller, B. T., Fahrni, S. M., Stafford jr., T., Grimes, V. & Renouf, M. A. P. & 36 others, Cybulski, J., Lynnerup, N., Lahr, M. M., Britton, K., Knecht, R., Arneborg, J., Metspalu, M., Cornejo, O. E., Malaspinas, A. S., Wang, Y., Rasmussen, M., Raghavan, V., Hansen, T. V. O., Khusnutdinova, E., Pierre, T. L., Dneprovsky, K., Andreasen, C., Lange, H., Hayes, M. G., Coltrain, J., Spitsyn, V. A., Götherström, A., Orlando, L. A. A., Kivisild, T., Villems, R., Crawford, M. H., Nielsen, F. C., Dissing, J., Heinemeier, J., Meldgaard, M., Bustamante, C., O'Rourke, D. H., Jakobsson, M., Gilbert, M. T. P., Nielsen, R. & Willerslev, E., 29 Aug 2014, In: Science. 345, 6200, 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

178 Citations (Scopus)

2013

Classifications within molecular subtypes enables identification of BRCA1/BRCA2 mutation carriers by RNA tumor profiling

Larsen, M. J., Kruse, T. A., Tan, Q., Lænkholm, A.-V., Bak, M., Lykkesfeldt, A. E., Sørensen, K. P., Hansen, T. V. O., Ejlertsen, B., Gerdes, A.-M. & Thomassen, M., 21 May 2013, In: P L o S One. 8, 5, 12 p., e64268.

Research output: Contribution to journal › Journal article › Research › peer-review

59 Citations (Scopus)

Functional examination of MLH1, MSH2, and MSH6 intronic mutations identified in Danish colorectal cancer patients

Petersen, S. M., Dandanell, M., Rasmussen, L. J., Gerdes, A.-M., Krogh, L. N., Bernstein, I., Okkels, H., Wikman, F., Nielsen, F. C. & Hansen, T. V. O., 3 Oct 2013, In: BMC Medical Genetics. 14, p. 103

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

Permuth-Wey, J., Lawrenson, K., Shen, H. C., Velkova, A., Tyrer, J. P., Chen, Z., Lin, H.-Y., Chen, Y. A., Tsai, Y.-Y., Qu, X., Ramus, S. J., Karevan, R., Lee, J., Lee, N., Larson, M. C., Aben, K. K., Anton-Culver, H., Antonenkova, N., Antoniou, A. C. & Armasu, S. M. & 160 others, Bacot, F., Baglietto, L., Bandera, E. V., Barnholtz-Sloan, J., Beckmann, M. W., Birrer, M. J., Bloom, G., Bogdanova, N., Brinton, L. A., Brooks-Wilson, A., Brown, R. J., Butzow, R., Cai, Q., Campbell, I., Chang-Claude, J., Chanock, S., Chenevix-Trench, G., Cheng, J. Q., Cicek, M. S., Coetzee, G. A., Cook, L. S., Couch, F. J., Cramer, D. W., Cunningham, J. M., Dansonka-Mieszkowska, A., Despierre, E., Doherty, J. A., Dörk, T., du Bois, A., Dürst, M., Easton, D. F., Eccles, D., Edwards, R., Ekici, A. B., Fasching, P. A., Fenstermacher, D. A., Flanagan, J. M., Garcia-Closas, M., Gentry-Maharaj, A., Giles, G. G., Glasspool, R. M., Gonzalez-Bosquet, J., Goodman, M. T., Gore, M., Górski, B., Gronwald, J., Hall, P., Halle, M. K., Harter, P., Heitz, F., Hillemanns, P., Hoatlin, M., Høgdall, C. K., Høgdall, E., Hosono, S., Jakubowska, A., Jensen, A., Jim, H., Kalli, K. R., Karlan, B. Y., Kaye, S. B., Kelemen, L. E., Kiemeney, L. A., Kikkawa, F., Konecny, G. E., Krakstad, C., Kjaer, S. K., Kupryjanczyk, J., Lambrechts, D., Lambrechts, S., Lancaster, J. M., Le, N. D., Leminen, A., Levine, D. A., Liang, D., Lim, B. K., Lin, J., Lissowska, J., Lu, K. H., Lubi?ski, J., Lurie, G., Massuger, L. F. A. G., Matsuo, K., McGuire, V., McLaughlin, J. R., Menon, U., Modugno, F., Moysich, K. B., Nakanishi, T., Narod, S. A., Nedergaard, L., Ness, R. B., Nevanlinna, H., Nickels, S., Noushmehr, H., Odunsi, K., Olson, S. H., Orlow, I., Paul, J., Pearce, C. L., Pejovic, T., Pelttari, L. M., Pike, M. C., Poole, E. M., Raska, P., Renner, S. P., Risch, H. A., Rodriguez-Rodriguez, L., Rossing, M. A., Rudolph, A., Runnebaum, I. B., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Severi, G., Shridhar, V., Shu, X.-O., Shvetsov, Y. B., Sieh, W., Song, H., Southey, M. C., Spiewankiewicz, B., Stram, D., Sutphen, R., Teo, S.-H., Terry, K. L., Tessier, D. C., Thompson, P. J., Tworoger, S. S., van Altena, A. M., Vergote, I., Vierkant, R. A., Vincent, D., Vitonis, A. F., Wang-Gohrke, S., Palmieri Weber, R., Wentzensen, N., Whittemore, A. S., Wik, E., Wilkens, L. R., Winterhoff, B., Woo, Y. L., Wu, A. H., Xiang, Y.-B., Yang, H. P., Zheng, W., Ziogas, A., Zulkifli, F., Phelan, C. M., Iversen, E., Schildkraut, J. M., Berchuck, A., Fridley, B. L., Goode, E. L., Pharoah, P. D. P., Monteiro, A. N. A., Sellers, T. A., Gayther, S. A., Study, A. C. & Hansen, T. V. O., 2013, In: Nature Communications. 4, p. 1-12 1627.

Research output: Contribution to journal › Journal article › Research › peer-review

79 Citations (Scopus)

Von Hippel-Lindau disease (vHL)

Binderup, M. L. M., Bisgaard, S. M. L., Harbud, V., Møller, H. U., Gimsing, S., Friis-Hansen, L., Hansen, T. V. O., Bagi, P., Knigge, U., Kosteljanetz, M., Bøgeskov, L., Thomsen, C., Gerdes, A.-M., Ousager, L. B. & Sunde, L., Dec 2013, In: Danish Medical Journal. 60, 12, p. B4763

Research output: Contribution to journal › Journal article › Research › peer-review

49 Citations (Scopus)

2012

Functional characterization of MLH1 missense variants identified in Lynch Syndrome patients

Andersen, S. D., Liberti, S. E., Lützen, A., Drost, M., Bernstein, I., Nilbert, M., Dominguez, M., Nyström, M., Hansen, T. V. O., Christoffersen, J. W., Jäger, A. C., de Wind, N., Nielsen, F. C., Tørring, P. M. & Rasmussen, L. J., Dec 2012, In: Human Mutation. 33, 12, p. 1647-1655 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

2011

A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics

Moltke, I., Albrechtsen, A., Hansen, T. V. O., Nielsen, F. C. & Nielsen, R., Jul 2011, In: Genome Research. 21, 7, p. 1168-80 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers

Ramus, S. J., Kartsonaki, C., Gayther, S. A., Pharoah, P. D. P., Sinilnikova, O. M., Beesley, J., Chen, X., McGuffog, L., Healey, S., Couch, F. J., Wang, X., Fredericksen, Z., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Roversi, G., Barile, M., Viel, A. & Allavena, A. & 31 others, Ottini, L., Papi, L., Gismondi, V., Capra, F., Radice, P., Greene, M. H., Mai, P. L., Andrulis, I. L., Glendon, G., Ozcelik, H., Thomassen, M., Gerdes, A.-M., Kruse, T. A., Cruger, D., Jensen, U. B., Caligo, M. A., Olsson, H., Kristoffersson, U., Lindblom, A., Arver, B., Karlsson, P. W., Stenmark Askmalm, M., Borg, A., Neuhausen, S. L., Ding, Y. C., Nathanson, K. L., Domchek, S. M., Hansen, T. V. O., Jønson, L., Ejlertsen, B. & OCGN, 19 Jan 2011, In: National Cancer Institute. Journal (Print). 103, 2, p. 105-16 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

2010

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

Antoniou, A. C., Wang, X., Fredericksen, Z. S., McGuffog, L., Tarrell, R., Sinilnikova, O. M., Healey, S., Morrison, J., Kartsonaki, C., Lesnick, T., Ghoussaini, M., Barrowdale, D., Peock, S., Cook, M., Oliver, C., Frost, D., Eccles, D., Evans, D. G., Eeles, R. & Izatt, L. & 31 others, Chu, C., Douglas, F., Paterson, J., Stoppa-Lyonnet, D., Houdayer, C., Mazoyer, S., Giraud, S., Lasset, C., Remenieras, A., Caron, O., Hardouin, A., Berthet, P., Hogervorst, F. B. L., Rookus, M. A., Jager, A., van den Ouweland, A., Hoogerbrugge, N., van der Luijt, R. B., Meijers-Heijboer, H., Gómez García, E. B., Devilee, P., Vreeswijk, M. P. G., Lubinski, J., Jakubowska, A., Gronwald, J., Huzarski, T., Byrski, T., Gerdes, A.-M., Hansen, T. V. O., Nielsen, F. C. & EMBRACE, 1 Oct 2010, In: Nature Genetics. 42, 10, p. 885-92 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

253 Citations (Scopus)

Ancient human genome sequence of an extinct Palaeo-Eskimo

Rasmussen, M., Li, Y., Lindgreen, S., Pedersen, J. S., Albrechtsen, A., Moltke, I., Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, T., Wang, Y., Raghavan, M., Campos, P., Kamp, H. L. M., Wilson, A. S., Gledhill, A. & Tridico, S. & 32 others, Bunce, M., Lorenzen, E., Binladen, J. K. M. A., Guo, X., Zhao, J., Zhang, X., Zhang, H., Li, Z., Chen, M., Orlando, L. A. A., Kristiansen, K., Bak, M., Tommerup, N., Bendixen, C., Pierre, T. L., Grønnow, B., Meldgaard, M., Andreasen, C., Fedorova, S. A., Osipova, L. P., Higham, T. F. G., Ramsey, C. B., Hansen, T. V. O., Nielsen, F. C., Crawford, M. H., Brunak, S., Sicheritz-Pontén, T., Villems, R., Nielsen, R., Krogh, A., Wang, J. & Willerslev, E., 11 Feb 2010, In: Nature. 463, 7282, p. 757-762 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

485 Citations (Scopus)

Common genetic variants and modification of penetrance of BRCA2-associated breast cancer

Gaudet, M. M., Kirchhoff, T., Green, T., Vijai, J., Korn, J. M., Guiducci, C., Segrè, A. V., McGee, K., McGuffog, L., Kartsonaki, C., Morrison, J., Healey, S., Sinilnikova, O. M., Stoppa-Lyonnet, D., Mazoyer, S., Gauthier-Villars, M., Sobol, H., Longy, M., Frenay, M. & GEMO Study Collaborators & 31 others, Hogervorst, F. B. L., Rookus, M. A., Collée, J. M., Hoogerbrugge, N., van Roozendaal, K. E. P., Piedmonte, M., Rubinstein, W., Nerenstone, S., Van Le, L., Blank, S. V., Caldés, T., de la Hoya, M., Nevanlinna, H., Aittomäki, K., Lazaro, C., Blanco, I., Arason, A., Johannsson, O. T., Barkardottir, R. B., Devilee, P., Olopade, O. I., Neuhausen, S. L., Wang, X., Fredericksen, Z. S., Peterlongo, P., Manoukian, S., Barile, M., Viel, A., Overeem Hansen, T. V., Nielsen, F. C. & HEBON Study Collaborators, 1 Oct 2010, In: P L o S Genetics. 6, 10, p. e1001183

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75 Citations (Scopus)

Identification of a Danish breast/ovarian cancer family double heterozygote for BRCA1 and BRCA2 mutations

Steffensen, A. Y., Jønson, L., Ejlertsen, B., Gerdes, A.-M., Nielsen, F. C. & Hansen, T. V. O., 1 Sept 2010, In: Familial Cancer. 9, 3, p. 283-7 5 p.

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13 Citations (Scopus)

Identification of a novel BRCA1 nucleotide 4803delCC/c.4684delCC mutation and a nucleotide 249T>A/c.130T>A (p.Cys44Ser) mutation in two Greenlandic Inuit families: implications for genetic screening of Greenlandic Inuit families with high risk for breast and/or ovarian cancer

Hansen, T. V. O., Jønson, L., Albrechtsen, A., Steffensen, A. Y., Bergsten, E. B., Myrhøj, T., Ejlertsen, B. L. & Nielsen, F. C., Nov 2010, In: Breast Cancer Research and Treatment. 124, 1, p. 259-264 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2009

Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families

Hansen, T. V. O., Jønson, L., Albrechtsen, A., Andersen, M. K., Ejlertsen, B. & Nielsen, F. C., May 2009, In: Breast Cancer Research and Treatment. 115, 2, p. 315-323 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

46 Citations (Scopus)

2007

Blau syndrome-associated mutations in exon 4 of the caspase activating recruitment domain 15 (CARD 15) gene are not found in ethnic Danes with sarcoidosis

Milman, N., Nielsen, F. C., Hviid, T. V. F. & Hansen, T. V. O., Dec 2007, In: Clinical Respiratory Journal. 1, 2, p. 74-9 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

2006

Favourable effect of TNF-alpha inhibitor (infliximab) on Blau syndrome in monozygotic twins with a de novo CARD15 mutation

Milman, N., Andersen, C. B., Hansen, A., van Overeem Hansen, T., Nielsen, F. C., Fledelius, H., Ahrens, P. & Nielsen, O. H., Dec 2006, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 114, 12, p. 912-9 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

71 Citations (Scopus)

2005

Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer

Hammer, N. A., Hansen, T. V. O., Byskov, A. G., Rajpert-De Meyts, E., Grøndahl, M. L., Bredkjaer, H. E., Wewer, U. M., Christiansen, J. & Nielsen, F. C., 2005, In: Reproduction. 130, 2, p. 203-12 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

85 Citations (Scopus)

2004

Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice

Hansen, T. V. O., Hammer, N. A., Nielsen, J., Madsen, M., Dalbaeck, C., Wewer, U. M., Christiansen, J. & Nielsen, F. C., 2004, In: Molecular and Cellular Biology. 24, 10, p. 4448-64 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

158 Citations (Scopus)

Thomas van Overeem Hansen

Research output

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