Thomas Mandrup-Poulsen

Research output

Research output per year 1985 2005 2007 2008 2009 2010 2011 2012 2013 2014 2016 2018 2019 2019

• 158 Journal article
• 4 Review
• 3 Book chapter
• 3 Conference abstract for conference
• 13 More
  • 3 Poster
  • 3 Comment/debate
  • 2 Letter
  • 2 Other contribution
  • 1 Article in proceedings
  • 1 Conference abstract in journal
  • 1 Conference article

Research output per year

Research output per year

Search results

• 2010

  Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines

  Lundh, M., Christensen, D. P., Rasmussen, D. N., Mascagni, P., Dinarello, C. A., Billestrup, N., Grunnet, L. G. & Mandrup-Poulsen, T., 1 Dec 2010, In: Diabetologia. 53, 12, p. 2569-78 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Insulin-Secreting Cells 100%
  • Lysine 90%
  • Cytokines 57%
  • givinostat hydrochloride 46%
  • Histone Deacetylases 9%
  53 Citations (Scopus)

• Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes

  Reinhard, H., Jacobsen, P. K., Lajer, M., Pedersen, N., Billestrup, N., Mandrup-Poulsen, T., Parving, H-H. & Rossing, P., 1 Oct 2010, In: Diabetologica. 53, 10, p. 2129-33 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Endothelial Progenitor Cells 100%
  • Type 2 Diabetes Mellitus 61%
  • Blood Cells 16%
  • Cell Count 15%
  • Diabetic Angiopathies 13%
  28 Citations (Scopus)

• Role of IL-1beta in type 2 diabetes

  Dinarello, C. A., Donath, M. Y. & Mandrup-Poulsen, T., 1 Aug 2010, In: Current Opinion in Endocrinology, Diabetes and Obesity. 17, 4, p. 314-21 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Interleukin-1 100%
  • Type 2 Diabetes Mellitus 75%
  • Interleukin-1 Receptors 35%
  • Nonesterified Fatty Acids 20%
  • Inflammation 17%
  231 Citations (Scopus)
• 2009

  DIAMAP team group. Europe draws up a map to a better future: Diabetes Breakthrough

  Mandrup-Poulsen, T., 2009

  Research output: Other contribution › Communication

• DIAMAP team group. Invitation to diabetes researchers and funding agencies to participate in an innovative European project.

  Mandrup-Poulsen, T., 2009

  Research output: Other contribution › Communication

• Differential transcriptional regulation of extra cellular matrix modulating genes by proinflammatory cytokines in ins-1 cells

  Hansen, J. B., Tonnesen, M., Friberg, J., Brünner, N. & Mandrup-Poulsen, T., 2009. 1 p.

  Research output: Contribution to conference › Conference abstract for conference › Research

• Functional SOCS1 polymorphisms are associated with variation in obesity in whites

  Gylvin, T., Ek, J., Nolsøe, R., Albrechtsen, A., Andersen, G., Bergholdt, R., Brorsson, C., Bang-Berthelsen, C. H., Hansen, T., Karlsen, A. E., Billestrup, N., Borch-Johnsen, K., Jørgensen, T., Pedersen, O., Mandrup-Poulsen, T., Nerup, J. & Pociot, F. M., 2009, In: Diabetes, Obesity and Metabolism. 11, 3, p. 196-203 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • European Continental Ancestry Group 100%
  • Type 2 Diabetes Mellitus 81%
  • Obesity 75%
  • Cytokines 66%
  • Glucose 34%
  19 Citations (Scopus)

• G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction

  Holst, B., Egerod, K. L., Jin, C., Petersen, P. S., Østergaard, M. V., Hald, J., Sprinkel, A. M. E., Størling, J., Mandrup-Poulsen, T., Holst, J. J., Thams, P., Orskov, C., Wierup, N., Sundler, F., Madsen, O. D. & Schwartz, T. W., 2009, In: Endocrinology. 150, 6, p. 2577-85 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Islets of Langerhans 100%
  • G-Protein-Coupled Receptors 99%
  • Insulin Derivative 84%
  • Glucose 73%
  • Insulin 40%
  65 Citations (Scopus)

• IL-1 beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells

  Jacobsen, M. L. B., Ronn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, T. & Billestrup, N., 2009, In: Diabetologia. 52, 2, p. 281-288 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• IL-1 receptor antagonism and muscle gene expression in patients with type 2 diabetes

  Berchtold, L. A., Larsen, C. M., Vaag, A., Faulenbach, M., Workman, C. T., Kruhøffer, M., Donath, M. & Mandrup-Poulsen, T., 2009, In: European Cytokine Network. 20, 2, p. 81-87 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Interleukin 1 Receptor Blocking Agent 100%
  • Interleukin-1 Receptors 63%
  • Interleukin 1 Receptor Antagonist Protein 48%
  • Type 2 Diabetes Mellitus 40%
  • Muscles 32%
  10 Citations (Scopus)

• Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells

  Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, N., Eizirik, D. L., Størling, J. & Mandrup-Poulsen, T., Sept 2009, In: Endocrinology. 150, 9, p. 4094-103 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Thapsigargin 100%
  • Endoplasmic Reticulum Stress 71%
  • NF-kappa B 68%
  • L-Penicillamine 67%
  • Penicillamine 55%
  33 Citations (Scopus)

• Inhibition of Nuclear Factor-kappa B or Bax Prevents Endoplasmic Reticulum Stress-But Not Nitric Oxide-Mediated Apoptosis in INS-1E Cells

  Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, N., Eizirik, D. L., Storling, J. & Mandrup-Poulsen, T., 2009, In: Endocrinology. 150, 9, p. 4094-4103 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells

  Grunnet, L. G., Aikin, R., Tonnesen, M. F., Paraskevas, S., Blaabjerg, L., Størling, J., Rosenberg, L., Billestrup, N., Maysinger, D. & Mandrup-Poulsen, T., 2009, In: Diabetes. 58, 8, p. 1807-15 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cytokines 100%
  • Calcineurin 50%
  • Caspase 9 45%
  • Cytochromes c 43%
  • DNA Fragmentation 43%
  151 Citations (Scopus)

• Proinflammatory Cytokines Inhibit TIMP-1 Expression but Induces PAI-1 and CD63 Expression in INS-1 Cells

  Hansen, J. B., Brunner, N. & Mandrup-Poulsen, T., 2009.

  Research output: Contribution to conference › Poster › Research

• Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells

  Bruun, C., Heding, P. E., Rønn, S. G., Frobøse, H., Rhodes, C. J., Mandrup-Poulsen, T. & Billestrup, N., 2009, In: Molecular and Cellular Endocrinology. 311, 1-2, p. 32-8 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tumor Necrosis Factor-alpha 100%
  • Mitogen 99%
  • Growth Hormone 90%
  • Cytokines 87%
  • Apoptosis 85%
  28 Citations (Scopus)

• Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes

  Larsen, C. M., Faulenbach, M., Vaag, A., Ehses, J. A., Donath, M. Y. & Mandrup-Poulsen, T., 2009, In: Diabetes Care. 32, 9, p. 1663-8 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Interleukin 1 Receptor Antagonist Protein 100%
  • Interleukin-1 Receptors 87%
  • Interleukins 80%
  • Type 2 Diabetes Mellitus 55%
  • Interleukin-1 55%
  289 Citations (Scopus)

• The anti-interleukin-1 in type 1 diabetes action trial - Background and rationale

  Pickersgill, L. M. S. & Mandrup-Poulsen, T., 2009, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 25, 4, p. 321-324 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• The global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation

  Kolb, H. & Mandrup-Poulsen, T., 2009, In: Diabetologia. 53, 1, p. 10-20 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Epidemics 100%
  • Life Style 94%
  • Type 2 Diabetes Mellitus 87%
  • Inflammation 68%
  • Overnutrition 43%
  210 Citations (Scopus)
• 2008

  Behandling af diabetes mellitus med biologiske laegemidler.

  Translated title of the contribution: Treatment of diabetes mellitus with biologic therapeuticsLarsen, C. M. & Mandrup-Poulsen, T., 2008, In: Ugeskrift for læger. 170, 24, p. 2134-7 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  1 Citation (Scopus)

• Circulating endothelial progenitor cell number in long-standing type 1 diabetic patients

  Reinhard, H., Jacobsen, P. K., Tarnov, L., Astrup, A. S., Lajer, M., Pedersen, N., Billestrup, N., Mandrup-Poulsen, T., Kastrup, J., Parving, H. H. & Rossing, P., 2008, In: Diabetologia. 51, Suppl. 1, p. S531-S531

  Research output: Contribution to journal › Journal article › Research › peer-review

• IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells

  Jacobsen, M. L. B., Rønn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, T. & Billestrup, N., 2008, In: Diabetologia. 52, 2, p. 281-8 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Chemokines 100%
  • Insulin 72%
  • Cytokines 66%
  • fas Receptor 24%
  • Insulinoma 22%
  19 Citations (Scopus)

• MicroRNAs are potential posttranscriptional regulators of Bcl-2 family members after cytokine stimulation in INS-1 cells

  Bang-Berthelsen, C. H., Grunnet, L. G., Kutlu, B., Johansson, F., Eizirik, D., Pociot, F. & Mandrup-Poulsen, T., 2008, In: FEBS Journal. 275, Suppl. 1, p. 152-152

  Research output: Contribution to journal › Journal article › Research › peer-review

• Mixed-meal tolerance test versus glucagon stimulation test for the assessment of beta-cell function in therapeutic trials in type 1 diabetes.

  Greenbaum, C. J., Mandrup-Poulsen, T., McGee, P. F., Battelino, T., Haastert, B., Ludvigsson, J., Pozzilli, P., Lachin, J. M., Kolb, H., Type 1 Diabetes Trial Net Research Group & European C-Peptide Trial Study Group, 2008, In: Diabetes Care. 31, 10, p. 1966-71 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • C-Peptide 100%
  • Glucagon 90%
  • Meals 78%
  • Type 1 Diabetes Mellitus 77%
  • Secretagogues 17%
  185 Citations (Scopus)

• Proliferation of sorted human and rat beta cells

  Parnaud, G., Bosco, D., Berney, T., Pattou, F., Kerr-Conte, J., Donath, M. Y., Bruun, C., Mandrup-Poulsen, T., Billestrup, N. & Halban, P. A., 2008, In: Diabetologia. 51, 1, p. 91-100 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Extracellular Matrix 100%
  • Intercellular Signaling Peptides and Proteins 96%
  • In Vitro Techniques 51%
  188 Citations (Scopus)

• Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection

  Rønn, S. G., Börjesson, A., Bruun, C., Heding, P. E., Frobøse, H., Mandrup-Poulsen, T., Karlsen, A. E., Rasschaert, J., Sandler, S. & Billestrup, N., 2008, In: Diabetologia. 51, 10, p. 1873-1882 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Islets of Langerhans 100%
  • Allografts 87%
  • Cytokines 61%
  • Insulinoma 41%
  • Interleukin-1 33%
  27 Citations (Scopus)

• The Faroese, a genetic isolate with a strong founder effect, allows the identification of Type 1 diabetes susceptibility regions

  Nolsoe, R., Roin, J., Deckert, M., Bergholdt, R., Kelly, J., Brorsson, C., Harley, J., Olsen, S., Pociot, F. & Mandrup-Poulsen, T., 2008, In: Clinical Immunology. 127, Suppl. S, p. S105-S105

  Research output: Contribution to journal › Journal article › Research › peer-review

• The imidazoline RX871024 induces death of proliferating insulin-secreting cells by activation of c-jun N-terminal kinase

  Zaitseva, I. I., Storling, J., Mandrup-Poulsen, T., Berggren, P. O. & Zaitsev, S. V., 2008, In: Cellular and Molecular Life Sciences. 65, 7-8, p. 1248-1255 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  10 Citations (Scopus)

• The role of NCAM signaling in the pancreatic beta-cell

  Grunnet, L. G., Storling, J., Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, N., Bock, E. & Mandrup-Poulsen, T., 2008, In: FEBS Journal. 275, Suppl. 1

  Research output: Contribution to journal › Journal article › Research › peer-review

• The use of interleukin-1-receptor antagonists in the treatment of diabetes mellitus.

  Donath, M. Y. & Mandrup-Poulsen, T., 2008, In: Nature Clinical Practice Endocrinology & Metabolism. 4, 5, p. 240-1 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  33 Citations (Scopus)
• 2007

  Ætiologi og patogenese, Type 1

  Bergholdt, R., Larsen, C. M., Pociot, F. M., Mandrup-Poulsen, T. R., Hilsted, J. C., Christensen, J. S. & Borch-Johnsen, K., 2007, Diabetes. 1 ed. København: Handelshøjskolens Forlag, Vol. 6. p. -

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission

  Schloot, N. C., Hanifi-Moghaddam, P., Aabenhus-Andersen, N., Alizadeh, B. Z., Saha, M. T., Knip, M., Devendra, D., Wilkin, T., Bonifacio, E., Roep, B. O., Kolb, H. & Mandrup-Poulsen, T. R., 2007, In: Diabetic Medicine. 24, 5, p. 512-520 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  34 Citations (Scopus)

• Cytokines and beta-cell biology: from concept to clinical translation

  Donath, M. Y., Storling, J., Berchtold, L. A., Billestrup, N. & Mandrup-Poulsen, T., 2007, In: Endocrine Reviews. 29, 3, p. 334-50 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Genetically Modified Animals 100%
  • Cell Biology 69%
  • Animal Models 57%
  • Clinical Trials 52%
  • Cytokines 49%
  161 Citations (Scopus)

• Diabetes and suppressors of cytokine signaling proteins.

  Rønn, S. G., Billestrup, N. & Mandrup-Poulsen, T., 2007, In: Diabetes. 56, 2, p. 541-8 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  42 Citations (Scopus)

• Glutaminsyre-decarboxylase-antistoffer og diabetes.

  Translated title of the contribution: Auto-antibodies against glutamic acid decarboxylase and diabetesMandrup-Poulsen, T., 2007, In: Ugeskrift for læger. 169, 4, p. 300-4 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  2 Citations (Scopus)

• Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

  Larsen, L., Tonnesen, M. F., Ronn, S. G., Storling, J., Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, N. & Mandrup-Poulsen, T. R., 2007, In: Diabetologia. 50, 4, p. 779-789 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  96 Citations (Scopus)

• Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

  Larsen, L., Tonnesen, M., Ronn, S. G., Størling, J., Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, N. & Mandrup-Poulsen, T., Apr 2007, In: Diabetologia. 50, 4, p. 779-89 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Histone Deacetylases 100%
  • NF-kappa B 65%
  • Cytokines 53%
  • Nitric Oxide 29%
  • Insulin Secretion 24%
  96 Citations (Scopus)

• Interleukin-1 receptorantagonistbehandling af patienter med type 2-diabetes--sekundaerpublikation.

  Translated title of the contribution: Interleukin-1 receptor antagonist-treatment of patients with type 2 diabetesLarsen, C. M., Faulenbach, M., Vaag, A., Vølund, A., Ehses, J., Seifert, B., Mandrup-Poulsen, T. & Donath, M., 2007, In: Ugeskrift for læger. 169, 45, p. 3868-71 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  8 Citations (Scopus)

• Interleukin-1-receptor antagonist in type 2 diabetes mellitus.

  Larsen, C. M., Faulenbach, M., Vaag, A., Vølund, A., Ehses, J. A., Seifert, B., Mandrup-Poulsen, T. & Donath, M. Y., 2007, In: New England Journal of Medicine. 356, 15, p. 1517-26 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Interleukin-1 Receptors 100%
  • Type 2 Diabetes Mellitus 63%
  • Interleukin 1 Receptor Antagonist Protein 57%
  • Glycated Hemoglobin A 29%
  • Insulin Resistance 23%
  1291 Citations (Scopus)

• Interleukin-1-receptor antagonist in type 2 diabetes mellitus - Reply

  Mandrup-Poulsen, T. R., Seifert, B. & Donath, M. Y., 2007, In: New England Journal of Medicine. 357, 3, p. 303-303

  Research output: Contribution to journal › Journal article › Research › peer-review

• Lost in translation

  Frank, L. & Mandrup-Poulsen, T., 2007, In: Weekendavisen. 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• The Fas pathway is involved in pancreatic beta cell secretory function.

  Schumann, D. M., Maedler, K., Franklin, I., Konrad, D., Størling, J., Böni-Schnetzler, M., Gjinovci, A., Kurrer, M. O., Gauthier, B. R., Bosco, D., Andres, A., Berney, T., Greter, M., Becher, B., Chervonsky, A. V., Halban, P. A., Mandrup-Poulsen, T., Wollheim, C. B. & Donath, M. Y., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 8, p. 2861-6 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Insulin-Secreting Cells 100%
  • Insulin 63%
  • NF-kappa B kinase 27%
  • Death Domain Receptors 19%
  • Caspase Inhibitors 18%
  61 Citations (Scopus)

• Type 1 diabetes - the copenhagen model

  Mandrup-Poulsen, T. R., Binder, C., Deckert, T. & Nerup, J., 2007, Diabetes og Danmark. 1 ed. Gad, p. 184-195 11 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
• 2006

  Association of interferon-gamma and interleukin 10 genotypes and serum levels with partial clinical remission in type 1 diabetes

  Alizadeh, B. Z., Hanifi-Moghaddam, P., Eerligh, P., van der Slik, A. R., Kolb, H., Kharagjitsingh, A. V., Pereira Arias, A. M., Ronkainen, M., Knip, M., Bonfanti, R., Bonifacio, E., Prasad, D., Wilkin, T., Giphart, M. J., Koeleman, B. P. C., Nolsøe, R., Mandrup-Poulsen, T., Schloot, N. C., Roep, B. O. & DIABMARKER Study Group, 1 Sept 2006, In: Clinical and Experimental Immunology. 145, 3, p. 480-4 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Interferon-gamma 100%
  • Type 1 Diabetes Mellitus 99%
  • Interleukin-10 99%
  • Genotype 80%
  • Serum 50%
  22 Citations (Scopus)

• Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation.

  Ortis, F., Cardozo, A. K., Crispim, D., Störling, J., Mandrup-Poulsen, T. & Eizirik, D. L., 2006, In: Molecular Endocrinology. 20, 8, p. 1867-79 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • NF-kappa B 100%
  • Insulin 63%
  • Cytokines 58%
  • Gene Expression 56%
  • Insulin-Secreting Cells 9%
  104 Citations (Scopus)

• Growth arrest- and DNA-damage-inducible 45beta gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1beta-induced apoptosis in insulin-producing INS-1E cells

  Larsen, C. M., Døssing, M. G., Papa, S., Franzoso, G., Billestrup, N. & Mandrup-Poulsen, T., 1 May 2006, In: Diabetologia. 49, 5, p. 980-9 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • JNK Mitogen-Activated Protein Kinases 100%
  • Extracellular Signal-Regulated MAP Kinases 96%
  • DNA Damage 77%
  • Insulin 60%
  • Apoptosis 54%
  30 Citations (Scopus)

• IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line

  Petersen, L. G., Størling, J., Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, N., Bock, E. & Mandrup-Poulsen, T., 2006, In: Diabetologia. 49, 8, p. 1864-75 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Neural Cell Adhesion Molecules 100%
  • Fibroblast Growth Factor Receptors 97%
  • Mitogen-Activated Protein Kinases 61%
  • Ligands 53%
  • Cell Line 44%
  14 Citations (Scopus)

• IL-1β-induced pro-apoptotic signaling is facilitated by NCAM/FGF receptor signaling and inhibited by the C3d ligand in the INS-1E rat beta cell line

  Petersen, L. G., Størling, J., Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, N., Bock, E. M. & Mandrup-Poulsen, T. R., 2006, In: Diabetologia. 49, p. 1864-75

  Research output: Contribution to journal › Journal article › Research › peer-review

• Plasma cytokine levels in young and elderly twins: genes versus environment and relation to in vivo insulin action

  Grunnet, L., Poulsen, P., Klarlund Pedersen, B., Mandrup-Poulsen, T. & Vaag, A., 1 Feb 2006, In: Diabetologia. 49, 2, p. 343-50 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tumor Necrosis Factor Receptors 100%
  • Twins 92%
  • Insulin 59%
  • Elderly 58%
  • Cytokines 54%
  19 Citations (Scopus)

• RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines.

  Zaitseva, I. I., Sharoyko, V., Størling, J., Efendic, S., Guerin, C., Mandrup-Poulsen, T., Nicotera, P., Berggren, P-O. & Zaitsev, S. V., 2006, In: Biochemical and Biophysical Research Communications. 347, 4, p. 1121-8 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • 2-(2-imidazolin-2-yl)-1-phenyl-1H-indole 100%
  • Imidazoline 61%
  • Insulin-Secreting Cells 50%
  • efaroxan 40%
  • Imidazolines 35%
  8 Citations (Scopus)

• Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex.

  Frobøse, H., Rønn, S. G., Heding, P. E., Mendoza, H., Cohen, P., Mandrup-Poulsen, T. & Billestrup, N., 2006, In: Molecular Endocrinology. 20, 7, p. 1587-96 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • TNF Receptor-Associated Factor 6 100%
  • Interleukin-1 68%
  • Cytokines 42%
  • NF-kappa B 32%
  • Ubiquitination 24%
  122 Citations (Scopus)