Research output per year
Research output per year
Search results
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2019
Mesodermal induction of pancreatic fate commitment
Seymour, P. A. & Serup, P., Aug 2019, In: Seminars in Cell and Developmental Biology. 92, p. 77-88Research output: Contribution to journal › Review › peer-review
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2018
Dll1 and Jag1 are differentially required to specify proximal and distal pancreatic duct compartments.
Seymour, P. A., Collin, C. A., Jorgensen, M. C., Imayoshi, I., Kageyama, R. & Serup, P., 2018, (E-pub ahead of print) In: bioRxiv, Developmental Biology. p. 1-36 36 p.Research output: Contribution to journal › Journal article › Research
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Inhibition of Cdk5 Promotes β-Cell Differentiation From Ductal Progenitors
Liu, K-C., Leuckx, G., Sakano, D., Seymour, P. A., Mattsson, C. L., Rautio, L., Staels, W., Verdonck, Y., Serup, P., Kume, S., Heimberg, H. & Andersson, O., 1 Jan 2018, In: Diabetes. 67, 1, p. 58-70 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanosignalling via integrins directs fate decisions of pancreatic progenitors
Mamidi, A., Prawiro, C., Seymour, P. A., de Lichtenberg, K. H., Jackson, A., Serup, P. & Semb, H., 6 Dec 2018, In: Nature. 564, 7734, p. 114-118 5 p.Research output: Contribution to journal › Letter › peer-review
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Notch controls multiple pancreatic cell fate regulators through direct hes1-mediated repression.
de Lichtenberg, K. H., Seymour, P. A., Joergensen, M. C., Kim, Y-H., Grapin-Botton, A., Magnuson, M. A., Nakic, N., Ferrer, J. & Serup, P., 2018, (E-pub ahead of print) In: bioRxiv, Developmental Biology. p. 1-30 30 p.Research output: Contribution to journal › Journal article › Research
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2016
Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo
Horn, S., Kirkegaard, J. S., Hoelper, S., Seymour, P. A., Rescan, C., Nielsen, J. H., Madsen, O. D., Jensen, J. N., Kruger, M., Gronborg, M. & Ahnfelt-Rønne, J., Jan 2016, In: Molecular endocrinology (Baltimore, Md.). 30, 1, p. 133-143 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2015
A conserved role for Notch in priming the cellular response to Shh through ciliary localisation of the key Shh transducer, Smoothened
Stasiulewicz, M., Gray, S., Mastromina, I., Silva, J. C., Bjorklund, M., Seymour, P. A., Booth, D., Thompson, C., Green, R., Hall, E. A., Serup, P. & Dale, J. K., 1 Jul 2015, In: Development. 142, p. 2291-2303 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells
Shih, H. P., Seymour, P. A., Patel, N. A., Xie, R., Wang, A., Liu, P. P., Yeo, G. W., Magnuson, M. A. & Sander, M., 13 Oct 2015, In: Cell Reports. 13, 2, p. 326-36 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pairing-up SOX to kick-start beta cell genesis
Grapin-Botton, A., Seymour, P. A. & Gradwohl, G., 1 May 2015, In: Diabetologia. 58, 5, p. 859-861 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2014
Sox9: a master regulator of the pancreatic program
Seymour, P. A., 2014, In: The Review of Diabetic Studies. 11, 1, p. 51-83 33 p.Research output: Contribution to journal › Review › peer-review
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2013
Bulking up on beta cells
Seymour, P. A. & Serup, P., 22 Aug 2013, In: Briefings from the New England Journal of Medicine (Spanish Edition). 369, 8, p. 777-9 3 p.Research output: Contribution to journal › Review › peer-review
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2012
A Sox9/Fgf feed-forward loop maintains pancreatic organ identity
Seymour, P. A., Shih, H. P., Patel, N. A., Freude, K. K., Xie, R., Lim, C. J. & Sander, M., 15 Sept 2012, In: Development. 139, 18, p. 3363-72 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2011
Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development
Seymour, P. A. & Sander, M., Feb 2011, In: Diabetes. 60, 2, p. 364-76 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas
Kopp, J. L., Dubois, C. L., Schaffer, A. E., Hao, E., Shih, H. P., Seymour, P. A., Ma, J. & Sander, M., 15 Feb 2011, In: Development. 138, 4, p. 653-65 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sox9-haploinsufficiency causes glucose intolerance in mice
Dubois, C. L., Shih, H. P., Seymour, P. A., Patel, N. A., Behrmann, J. M., Ngo, V. & Sander, M., 2 Aug 2011, In: P L o S One. 6, 8, p. e23131Research output: Contribution to journal › Journal article › Research › peer-review
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2009
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function
Wang, S., Jensen, J. N., Seymour, P. A., Hsu, W., Dor, Y., Sander, M., Magnuson, M. A., Serup, P. & Gu, G., 16 Jun 2009, In: PNAS Early Edition. 106, 24, p. 9715-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2008
A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation
Seymour, P. A., Freude, K. K., Dubois, C. L., Shih, H-P., Patel, N. A. & Sander, M., 1 Nov 2008, In: Advances in Developmental Biology. 323, 1, p. 19-30 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2007
Immunohistochemical detection of beta-galactosidase or green fluorescent protein on tissue sections
Seymour, P. A. & Sander, M., 2007, In: Methods in Molecular Biology. 411, p. 13-23 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
SOX9 is required for maintenance of the pancreatic progenitor cell pool
Seymour, P. A., Freude, K. K., Tran, M. N., Mayes, E. E., Jensen, J., Kist, R., Scherer, G. & Sander, M., 6 Feb 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 6, p. 1865-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2004
Fission of pancreatic islets during postnatal growth of the mouse
Seymour, P. A., Bennett, W. R. & Slack, J. M. W., Feb 2004, In: Journal of Anatomy. 204, 2, p. 103-16 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice
Mellitzer, G., Martín, M., Sidhoum-Jenny, M., Orvain, C., Barths, J., Seymour, P. A., Sander, M. & Gradwohl, G., Nov 2004, In: Molecular Endocrinology. 18, 11, p. 2765-76 12 p.Research output: Contribution to journal › Journal article › Research › peer-review