Research output per year
Research output per year
Personal profile
Short presentation
I am specialized in molecular modeling/computational biochemistry, with a focus on the synergy between theory and experiment. My work involves:
- molecular modeling of nanostructures, proteins, carbohydrates, and small molecules
- molecular dynamics, molecular mechanics and density functional theory
- QSAR, molecular descriptors
I am currently working in the Knud J. Jensen group, applying modeling to understand the self-assembly of peptide-oligonucleotide conjugates.
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Keywords
- Faculty of Science
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Dive into the research topics where Niels Johan Christensen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 6 Similar Profiles
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Glycoconjugate Oxime Formation Catalyzed at Neutral pH: Mechanistic Insights and Applications of 1,4-Diaminobenzene as a Superior Catalyst for Complex Carbohydrates
Østergaard, M., Christensen, N. J., Hjuler, C. T., Jensen, K. J. & Thygesen, M. B., 18 Apr 2018, In: Bioconjugate Chemistry. 29, 4, p. 1219-1230 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synergy of Two Highly Specific Biomolecular Recognition Events: Aligning an AT-Hook Peptide in DNA Minor Grooves via Covalent Conjugation to 2′-Amino-LNA
Ejlersen, M., Christensen, N. J., Sørensen, K. K., Jensen, K. J., Wengel, J. & Lou, C., 18 Apr 2018, In: Bioconjugate Chemistry. 29, p. 1025-1029 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Folding Topology of a Short Coiled-Coil Peptide Structure Templated by an Oligonucleotide Triplex
Lou, C., Christensen, N. J., Martos Maldonado, M. C., Midtgaard, S. R., Ejlersen, M., Thulstrup, P. W., Sørensen, K. K., Jensen, K. J. & Wengel, J., 12 Jul 2017, In: Chemistry - A European Journal. 23, 39, p. 9297-9305 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oligonucleotides Containing Aminated 2′-Amino-LNA Nucleotides: Synthesis and Strong Binding to Complementary DNA and RNA
Lou, C., Samuelsen, S. V., Christensen, N. J., Vester, B. & Wengel, J., 2017, In: Bioconjugate Chemistry. 28, 4, p. 1214-1220 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Construction of insulin 18-mer nanoassemblies driven by coordination to Iron(II) and Zinc(II) ions at distinct sites
Munch, H. K., Nygård, J., Christensen, N. J., Engelbrekt, C., Østergaard, M., Porsgaard, T., Hoeg-Jensen, T., Zhang, J., Arleth, L., Thulstrup, P. W. & Jensen, K. J., 12 Feb 2016, In: Angewandte Chemie International Edition. 55, 7, p. 2378-2381 4 p.Research output: Contribution to journal › Letter › peer-review
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Peptide–oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic
Lou, C., Martos Maldonado, M. C., Madsen, C. S., Thomsen, R. P., Midtgaard, S. R., Christensen, N. J., Kjems, J., Thulstrup, P. W., Wengel, J. & Jensen, K. J., 28 Jul 2016, In: Nature Communications. 7, 9 p., 12294.Research output: Contribution to journal › Journal article › Research › peer-review
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A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template
Malik, L., Nygård, J., Christensen, N. J., Madsen, C. S., Rösner, H. I., Kragelund, B. B., Høiberg-Nielsen, R., Streicher, W., Arleth, L., Thulstrup, P. W. & Jensen, K. J., 1 Sept 2015, In: ChemBioChem. 16, 13, p. 1905-1918 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Specificity of the metalloregulator CueR for monovalent metal ions: possible functional role of a coordinated thiol?
Szunyogh, D., Szokolai, H., Thulstrup, P. W., Larsen, F. H., Gyurcsik, B., Christensen, N. J., Stachura, M. K., Hemmingsen, L. B. S. & Jancsó, A., 21 Dec 2015, In: Angewandte Chemie International Edition. 54, 52, p. 15756-15761 6 p.Research output: Contribution to journal › Journal article › Research › peer-review