Publikationer pr. år
Publikationer pr. år
Personlig profil
Kort præsentation
I am specialized in molecular modeling/computational biochemistry, with a focus on the synergy between theory and experiment. My work involves:
- molecular modeling of nanostructures, proteins, carbohydrates, and small molecules
- molecular dynamics, molecular mechanics and density functional theory
- QSAR, molecular descriptors
I am currently working in the Knud J. Jensen group, applying modeling to understand the self-assembly of peptide-oligonucleotide conjugates.
<span id='badgeCont566234' style='width:126px'><script src='http://labs.researcherid.com/mashlets?el=badgeCont566234&mashlet=badge&showTitle=false&className=a&rid=J-3820-2014'></script></span>
Emneord
- Det Natur- og Biovidenskabelige Fakultet
- Molecular modelling
- Computational Chemistry
- Computational Modeling
- Molecular Dynamics
- Quantum Chemistry
- Quantum Mechanics
Fingeraftryk
Dyk ned i forskningsemnerne, hvor Niels Johan Christensen er aktive. Disse emneetiketter kommer fra dennes persons arbejder. Sammen danner de et unikt fingerprint.
- 6 Lignende profiler
-
Glycoconjugate Oxime Formation Catalyzed at Neutral pH: Mechanistic Insights and Applications of 1,4-Diaminobenzene as a Superior Catalyst for Complex Carbohydrates
Østergaard, M., Christensen, N. J., Hjuler, C. T., Jensen, K. J. & Thygesen, M. B., 18 apr. 2018, I: Bioconjugate Chemistry. 29, 4, s. 1219-1230 12 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
Synergy of Two Highly Specific Biomolecular Recognition Events: Aligning an AT-Hook Peptide in DNA Minor Grooves via Covalent Conjugation to 2′-Amino-LNA
Ejlersen, M., Christensen, N. J., Sørensen, K. K., Jensen, K. J., Wengel, J. & Lou, C., 18 apr. 2018, I: Bioconjugate Chemistry. 29, s. 1025-1029 5 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
Folding Topology of a Short Coiled-Coil Peptide Structure Templated by an Oligonucleotide Triplex
Lou, C., Christensen, N. J., Martos Maldonado, M. C., Midtgaard, S. R., Ejlersen, M., Thulstrup, P. W., Sørensen, K. K., Jensen, K. J. & Wengel, J., 12 jul. 2017, I: Chemistry - A European Journal. 23, 39, s. 9297-9305 9 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
Oligonucleotides Containing Aminated 2′-Amino-LNA Nucleotides: Synthesis and Strong Binding to Complementary DNA and RNA
Lou, C., Samuelsen, S. V., Christensen, N. J., Vester, B. & Wengel, J., 2017, I: Bioconjugate Chemistry. 28, 4, s. 1214-1220 7 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
Construction of insulin 18-mer nanoassemblies driven by coordination to Iron(II) and Zinc(II) ions at distinct sites
Munch, H. K., Nygård, J., Christensen, N. J., Engelbrekt, C., Østergaard, M., Porsgaard, T., Hoeg-Jensen, T., Zhang, J., Arleth, L., Thulstrup, P. W. & Jensen, K. J., 12 feb. 2016, I: Angewandte Chemie International Edition. 55, 7, s. 2378-2381 4 s.Publikation: Bidrag til tidsskrift › Letter › peer review
-
Peptide–oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic
Lou, C., Martos Maldonado, M. C., Madsen, C. S., Thomsen, R. P., Midtgaard, S. R., Christensen, N. J., Kjems, J., Thulstrup, P. W., Wengel, J. & Jensen, K. J., 28 jul. 2016, I: Nature Communications. 7, 9 s., 12294.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template
Malik, L., Nygård, J., Christensen, N. J., Madsen, C. S., Rösner, H. I., Kragelund, B. B., Høiberg-Nielsen, R., Streicher, W., Arleth, L., Thulstrup, P. W. & Jensen, K. J., 1 sep. 2015, I: ChemBioChem. 16, 13, s. 1905-1918 14 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
Specificity of the metalloregulator CueR for monovalent metal ions: possible functional role of a coordinated thiol?
Szunyogh, D., Szokolai, H., Thulstrup, P. W., Larsen, F. H., Gyurcsik, B., Christensen, N. J., Stachura, M. K., Hemmingsen, L. B. S. & Jancsó, A., 21 dec. 2015, I: Angewandte Chemie International Edition. 54, 52, s. 15756-15761 6 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review