Mette Christine Jørgensen

2018

Dll1 and Jag1 are differentially required to specify proximal and distal pancreatic duct compartments.

Seymour, P. A., Collin, C. A., Jorgensen, M. C., Imayoshi, I., Kageyama, R. & Serup, P., 2018, (E-pub ahead of print) In: bioRxiv, Developmental Biology. p. 1-36 36 p.

Research output: Contribution to journal › Journal article › Research

Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice

Jørgensen, M. C., de Lichtenberg, K. H., Collin, C. A., Klinck, R., Ekberg, J. H., Engelstoft, M. S., Lickert, H. & Serup, P., Sept 2018, In: Development (Cambridge, England). 145, 17, p. 1-11 11 p., dev163568.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Notch controls multiple pancreatic cell fate regulators through direct hes1-mediated repression.

de Lichtenberg, K. H., Seymour, P. A., Joergensen, M. C., Kim, Y-H., Grapin-Botton, A., Magnuson, M. A., Nakic, N., Ferrer, J. & Serup, P., 2018, (E-pub ahead of print) In: bioRxiv, Developmental Biology. p. 1-30 30 p.

Research output: Contribution to journal › Journal article › Research

2014

The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube

Hanotel, J., Bessodes, N., Thélie, A., Hedderich, M., Parain, K., Driessche, B. V., Brandão, K. D. O., Kricha, S., Jorgensen, M. C., Grapin-Botton, A., Serup, P., Lint, C. V., Perron, M., Pieler, T., Henningfeld, K. A. & Bellefroid, E. J., 15 Feb 2014, In: Developmental Biology. 386, 2, p. 340–357 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

2012

Mind bomb 1 is required for pancreatic ß-cell formation

Horn, S., Kobberup, S., Jørgensen, M. C., Kalisz, M., Klein, T., Kageyama, R., Gegg, M., Lickert, H., Lindner, J., Magnuson, M. A., Kong, Y-Y., Serup, P., Ahnfelt-Rønne, J. & Jensen, J. N., 8 May 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 19, p. 7356-61 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

54 Citations (Scopus)

2011

A BAC transgenic Hes1-EGFP reporter reveals novel expression domains in mouse embryos

Klinck, R., Füchtbauer, E-M., Ahnfelt-Rønne, J., Serup, P., Jensen, J. N. & Jørgensen, M. C., Oct 2011, In: Gene Expression Patterns. 11, 7, p. 415-26 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism

Jørgensen, M. C., Ahnfelt-Rønne, J., Klinck, R., Jensen, J. N., Füchtbauer, E-M., Deering, T., MacDonald, R. J., Wright, C. V. E., Madsen, O. D. & Serup, P., 2011, In: Development. 139, 1, p. 33-45 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

50 Citations (Scopus)

2009

Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis

Bayha, E., Jørgensen, M. C., Serup, P. & Botton, A., 2009, In: PLOS ONE. 4, 6, p. e5845

Research output: Contribution to journal › Journal article › Research › peer-review

86 Citations (Scopus)

2008

Specificity of four monoclonal anti-NKx6-1 antibodies

Klinck, R., Serup, P., Madsen, O. D. & Jørgensen, M. C., Apr 2008, In: Journal of Histochemistry and Cytochemistry. 56, 4, p. 415-24 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

2007

An illustrated review of early pancreas development in the mouse

Jørgensen, M. C., Ahnfelt-Rønne, J., Hald, J., Madsen, O. D., Serup, P. & Hecksher-Sørensen, J., Oct 2007, In: Endocrine Reviews. 28, 6, p. 685-705 21 p.

Research output: Contribution to journal › Journal article › Research › peer-review

257 Citations (Scopus)

An improved method for three-dimensional reconstruction of protein expression patterns in intact mouse and chicken embryos and organs

Ahnfelt-Rønne, J., Jørgensen, M. C., Hald, J., Madsen, O. D., Serup, P. & Hecksher-Sørensen, J., Sept 2007, In: Journal of Histochemistry and Cytochemistry. 55, 9, p. 925-30 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

53 Citations (Scopus)

2006

Generation and characterization of monoclonal antibodies against the transcription factor Nkx6.1

Pedersen, I., Klinck, R., Hecksher-Sorensen, J., Zahn, S., Madsen, O. D., Serup, P. & Jørgensen, M. C., May 2006, In: Journal of Histochemistry and Cytochemistry. 54, 5, p. 567-74 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

2005

Endodermal expression of Nkx6 genes depends differentially on Pdx1

Pedersen, J. K., Nelson, S. B., Jørgensen, M. C., Henseleit, K. D., Fujitani, Y., Wright, C. V. E., Sander, M., Serup, P. & Beta Cell Biology Consortium, 15 Dec 2005, In: Developmental Biology. 288, 2, p. 487-501 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

54 Citations (Scopus)

2004

Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivity

Nielsen, K., Kruhøffer, M., Orntoft, T., Sparre, T., Wang, H., Wollheim, C., Jørgensen, M. C., Nerup, J. & Karlsen, A. E., Dec 2004, In: Diabetologia. 47, 12, p. 2185-99 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

2000

Pax4 represses pancreatic glucagon gene expression

Petersen, H. V., Jørgensen, M. C., Andersen, F. G., Jensen, J., F-Nielsen, T., Jørgensen, R., Madsen, O. D. & Serup, P., Apr 2000, In: Molecular Cell Biology Research Communications. 3, 4, p. 249-54 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

1999

Cloning and DNA-binding properties of the rat pancreatic beta-cell-specific factor Nkx6.1

Jørgensen, M. C., Vestergård Petersen, H., Ericson, J., Madsen, O. D. & Serup, P., 19 Nov 1999, In: FEBS Letters. 461, 3, p. 287-94 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

1997

Transcription factors contributing to the pancreatic beta-cell phenotype

Madsen, O. D., Jensen, J., Petersen, H. V., Pedersen, E. E., Oster, A., Andersen, F. G., Jørgensen, M. C., Jensen, P. B., Larsson, L. I. & Serup, P., Jun 1997, In: Hormone and Metabolic Research. 29, 6, p. 265-70 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

74 Citations (Scopus)

1996

Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1

Serup, P., Jensen, J., Andersen, F. G., Jørgensen, M. C., Blume, N., Holst, J. J. & Madsen, O. D., 20 Aug 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 17, p. 9015-20 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

129 Citations (Scopus)

Mette Christine Jørgensen

Research output

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