Marie Louise (Marieke) De Bruin

Research output

Research output per year 2000 2013 2014 2015 2016 2017 2018 2019 2019

• 107 Journal article
• 10 Conference abstract for conference
• 3 Letter
• 3 Review
• 3 More
  • 2 Comment/debate
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2016

  Understanding inconsistency in the results from observational pharmacoepidemiological studies: the case of antidepressant use and risk of hip/femur fractures

  Souverein, P. C., Abbing-Karahagopian, V., Martin, E., Huerta, C., de Abajo, F., Leufkens, H. G. M., Candore, G., Alvarez, Y., Slattery, J., Miret, M., Requena, G., Gil, M. J., Groenwold, R. H. H., Reynolds, R., Schlienger, R. G., Logie, J. W., de Groot, M. C. H., Klungel, O. H., van Staa, T. P., Egberts, T. C. G., & 2 othersDe Bruin, M. L. & Gardarsdottir, H., 1 Mar 2016, In: Pharmacoepidemiology and Drug Safety. 25 Suppl 1, p. 88-102 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hip Fractures 100%
  • Femur 85%
  • Antidepressive Agents 83%
  • Observational Studies 72%
  • Information Storage and Retrieval 56%
  16 Citations (Scopus)

• Use of incretin agents and risk of pancreatic cancer: a population-based cohort study

  Knapen, L. M., van Dalem, J., Keulemans, Y. C., van Erp, N. P., Bazelier, M. T., De Bruin, M. L., Leufkens, H. G. M., Croes, S., Neef, C., de Vries, F. & Driessen, J. H. M., 1 Mar 2016, In: Diabetes, Obesity and Metabolism Online. 18, 3, p. 258-65 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Incretins 100%
  • Pancreatic Neoplasms 72%
  • Cohort Studies 52%
  • Population 30%
  • Hypoglycemic Agents 29%
  20 Citations (Scopus)

• Validity of diagnostic codes and laboratory measurements to identify patients with idiopathic acute liver injury in a hospital database

  Udo, R., Maitland-van der Zee, A. H., Egberts, T. C. G., den Breeijen, J. H., Leufkens, H. G. M., van Solinge, W. W. & De Bruin, M. L., 1 Mar 2016, In: Pharmacoepidemiology and Drug Safety. 25 , Suppl 1, p. 21-8 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Databases 100%
  • Liver 85%
  • Wounds and Injuries 80%
  • International Classification of Diseases 42%
  • Bilirubin 40%
  10 Citations (Scopus)
• 2015

  An analysis of marketing authorisation applications via the mutual recognition and decentralised procedures in Europe

  Ebbers, H. C., Langedijk, J., Bouvy, J. C., Hoekman, J., Boon, W. P. C., de Jong, J. P. & De Bruin, M. L., 13 Oct 2015, In: European Journal of Clinical Pharmacology. 71, 10, p. 1237-44 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Marketing 100%
  • Referral and Consultation 67%
  • Licensure 59%
  • Pharmaceutical Preparations 3%
  3 Citations (Scopus)

• Are ECG monitoring recommendations before prescription of QT-prolonging drugs applied in daily practice? The example of haloperidol

  Warnier, M. J., Rutten, F. H., Souverein, P. C., de Boer, A., Hoes, A. W. & De Bruin, M. L., 1 Jul 2015, In: Pharmacoepidemiology and Drug Safety. 24, 7, p. 701-8 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Haloperidol 100%
  • Prescriptions 76%
  • Electrocardiography 74%
  • Pharmaceutical Preparations 37%
  • General Practitioners 10%
  14 Citations (Scopus)

• Classification of Recombinant Biologics in the EU: Divergence Between National Pharmacovigilance Centers

  Klein, K., De Bruin, M. L., Broekmans, A. W. & Stolk, P., 1 Dec 2015, In: BioDrugs. 29, 6, p. 373-9 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Pharmacovigilance 100%
  • European Union 87%
  • Biological Products 75%
  • Drug-Related Side Effects and Adverse Reactions 53%
  • Belgium 22%
  3 Citations (Scopus)

• Concomitant medication use and its implications on the hazard pattern in pharmacoepidemiological studies: Example of antidepressants, benzodiazepines and fracture risk

  Abbing-Karahagopian, V., Souverein, P. C., Korevaar, J. C., Leufkens, H. G. M., Egberts, T. C. G., Gardarsdottir, H. & De Bruin, M. L., 22 Sept 2015, In: Epidemiology Biostatistics and Public Health. 12, 3, e11273.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Benzodiazepines 100%
  • Antidepressive Agents 88%
  • medication 83%
  • adverse events 26%
  • Netherlands 16%
  2 Citations (Scopus)

• Data management and data analysis techniques in pharmacoepidemiological studies using a pre-planned multi-database approach: a systematic literature review

  Bazelier, M. T., Eriksson, I., de Vries, F., Schmidt, M. K., Raitanen, J., Haukka, J., Starup-Linde, J., De Bruin, M. L. & Andersen, M., 1 Sept 2015, In: Pharmacoepidemiology and Drug Safety. 24, 9, p. 897-905 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Data Management 100%
  • Data Analysis 55%
  • Systematic Reviews 55%
  • Databases 45%
  • Meta-Analysis 33%
  13 Citations (Scopus)

• Drug-induced progressive multifocal leukoencephalopathy: Lessons learned from contrasting natalizumab and rituximab

  Vermeer, N. S., Straus, S. M. J. M., Mantel-Teeuwisse, A. K., Hidalgo-Simon, A., Egberts, A. C. G., Leufkens, H. G. M. & De Bruin, M. L., 1 Nov 2015, In: Clinical Pharmacology and Therapeutics. 98, 5, p. 542-50 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Natalizumab 100%
  • Progressive Multifocal Leukoencephalopathy 95%
  • Rituximab 75%
  • Pharmaceutical Preparations 28%
  • Biological Products 27%
  17 Citations (Scopus)

• Epidemiology of adverse drug reactions in Europe: a review of recent observational studies

  Bouvy, J. C., De Bruin, M. L. & Koopmanschap, M. A., 1 May 2015, In: Drug Safety. 38, 5, p. 437-53 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Drug-Related Side Effects and Adverse Reactions 100%
  • Epidemiology 84%
  • Observational Studies 83%
  • Drug 56%
  • Outpatients 20%
  168 Citations (Scopus)

• Influence of metformin intake on the risk of bladder cancer in type 2 diabetes patients

  Goossens, M. E., Buntinx, F., Zeegers, M. P., Driessen, J. H. M., De Bruin, M. L. & De Vries, F., 1 Dec 2015, In: British Journal of Clinical Pharmacology. Supplement. 80, 6, p. 1464-72 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Metformin 100%
  • Urinary Bladder Neoplasms 89%
  • Type 2 Diabetes Mellitus 69%
  • Insulin 14%
  • Thiazolidinediones 13%
  14 Citations (Scopus)

• Risk of bladder cancer in patients with diabetes: a retrospective cohort study

  Goossens, M. E., Zeegers, M. P., Bazelier, M. T., De Bruin, M. L., Buntinx, F. & de Vries, F., 2015, In: B M J Open. 5, 6, p. e007470

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Urinary Bladder Neoplasms 100%
  • Cohort Studies 71%
  • Retrospective Studies 70%
  • Type 2 Diabetes Mellitus 44%
  • Mortality 30%
  12 Citations (Scopus)

• Strategy in Regulatory Decision-Making for Management of Progressive Multifocal Leukoencephalopathy

  Segec, A., Keller-Stanislawski, B., Vermeer, N. S., Macchiarulo, C., Straus, S. M., Hidalgo-Simon, A. & De Bruin, M. L., 1 Nov 2015, In: Clinical Pharmacology and Therapeutics. 98, 5, p. 502-5 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Progressive Multifocal Leukoencephalopathy 100%
  • Decision Making 59%
  • Pharmacovigilance 47%
  • Risk Assessment 30%
  • Monoclonal Antibodies 26%
  3 Citations (Scopus)

• The epidemiology of extra-articular manifestations in ankylosing spondylitis: a population-based matched cohort study

  Stolwijk, C., Essers, I., van Tubergen, A., Boonen, A., Bazelier, M. T., De Bruin, M. L. & de Vries, F., 1 Jul 2015, In: Annals of the Rheumatic Diseases. 74, 7, p. 1373-8 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Anterior Uveitis 100%
  • Ankylosing Spondylitis 99%
  • Psoriasis 73%
  • Inflammatory Bowel Diseases 70%
  • Epidemiology 68%
  71 Citations (Scopus)

• The risk of colorectal cancer in patients with type 2 diabetes: associations with treatment stage and obesity

  Peeters, P. J. H. L., Bazelier, M. T., Leufkens, H. G. M., de Vries, F. & De Bruin, M. L., Mar 2015, In: Diabetes Care. 38, 3, p. 495-502 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Colorectal Neoplasms 100%
  • Type 2 Diabetes Mellitus 94%
  • Obesity 87%
  • Duration of Therapy 26%
  • Therapeutics 20%
  72 Citations (Scopus)

• Traceability of biologicals: present challenges in pharmacovigilance

  Vermeer, N. S., Spierings, I., Mantel-Teeuwisse, A. K., Straus, S. M. J. M., Giezen, T. J., Leufkens, H. G. M., Egberts, T. C. G. & De Bruin, M. L., 1 Jan 2015, In: Expert Opinion on Drug Safety. 14, 1, p. 63-72 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Pharmacovigilance 100%
  • Biological Products 75%
  • Biosimilar Pharmaceuticals 35%
  • Databases 30%
  • Pharmacy 25%
  37 Citations (Scopus)

• Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence

  Bronsveld, H. K., ter Braak, B., Karlstad, Ø., Vestergaard, P., Starup-Linde, J., Bazelier, M. T., De Bruin, M. L., de Boer, A., Siezen, C. L. E., van de Water, B., van der Laan, J. W. & Schmidt, M. K., 5 Aug 2015, In: Breast cancer research : BCR. 17, p. 100

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Insulin Glargine 100%
  • Meta-Analysis 85%
  • Systematic Reviews 84%
  • Insulin 78%
  • Breast Neoplasms 73%
  34 Citations (Scopus)

• Use of the conditional marketing authorization pathway for oncology medicines in Europe

  Hoekman, J., Boon, W. P. C., Bouvy, J. C., Ebbers, H. C., de Jong, J. P. & De Bruin, M. L., 1 Nov 2015, In: Clinical Pharmacology and Therapeutics. 98, 5, p. 534-41 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Marketing 100%
  • Qualitative Research 8%
  • European Union 8%
  • Therapeutic Uses 6%
  • Research Design 6%
  33 Citations (Scopus)
• 2014

  Antidepressant prescribing in five European countries: application of common definitions to assess the prevalence, clinical observations, and methodological implications

  Abbing-Karahagopian, V., Huerta, C., Souverein, P. C., de Abajo, F., Leufkens, H. G. M., Slattery, J., Alvarez, Y., Miret, M., Gil, M., Oliva, B., Hesse, U., Requena, G., de Vries, F., Rottenkolber, M., Schmiedl, S., Reynolds, R., Schlienger, R. G., de Groot, M. C. H., Klungel, O. H., van Staa, T. P., & 4 othersvan Dijk, L., Egberts, A. C. G., Gardarsdottir, H. & De Bruin, M. L., Apr 2014, In: European Journal of Clinical Pharmacology. 70, 7, p. 849-857 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Antidepressive Agents 100%
  • Tricyclic Antidepressive Agents 43%
  • Population 43%
  • Serotonin Uptake Inhibitors 40%
  • Databases 33%
  87 Citations (Scopus)

• Genetic, clinical and pharmacological determinants of out-of-hospital cardiac arrest: rationale and outline of the AmsteRdam Resuscitation Studies (ARREST) registry

  Blom, M. T., van Hoeijen, D. A., Bardai, A., Berdowski, J., Souverein, P. C., De Bruin, M. L., Koster, R. W., de Boer, A. & Tan, H. L., 2014, In: Open Heart. 1, 1, p. e000112

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Out-of-Hospital Cardiac Arrest 100%
  • Resuscitation 74%
  • Registries 61%
  • Pharmacology 51%
  • Pharmacies 11%
  24 Citations (Scopus)

• Incidence rates and trends of hip/femur fractures in five European countries: comparison using e-healthcare records databases

  Requena, G., Abbing-Karahagopian, V., Huerta, C., De Bruin, M. L., Alvarez, Y., Miret, M., Hesse, U., Gardarsdottir, H., Souverein, P. C., Slattery, J., Schneider, C., Rottenkolber, M., Schmiedl, S., Gil, M., De Groot, M. C. H., Bate, A., Ruigómez, A., García Rodríguez, L. A., Johansson, S., de Vries, F., & 5 othersMontero, D., Schlienger, R., Reynolds, R., Klungel, O. H. & de Abajo, F. J., Jun 2014, In: Calcified Tissue International. 94, 6, p. 580-9 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hip Fractures 100%
  • Femur 85%
  • Delivery of Health Care 56%
  • Databases 55%
  • Incidence 45%
  35 Citations (Scopus)

• Long-term use of 5α-reductase inhibitors and the risk of male breast cancer

  Duijnhoven, R. G., Straus, S. M. J. M., Souverein, P. C., de Boer, A., Bosch, J. L. H. R., Hoes, A. W. & De Bruin, M. L., 31 Oct 2014, In: Cancer causes & control : CCC. 25, 11, p. 1577-82 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Male Breast Neoplasms 100%
  • Oxidoreductases 63%
  • Breast Neoplasms 35%
  • Odds Ratio 26%
  • Dutasteride 22%
  24 Citations (Scopus)

• QT interval prolongation in users of selective serotonin reuptake inhibitors in an elderly surgical population: a cross-sectional study

  van Haelst, I. M. M., van Klei, W. A., Doodeman, H. J., Warnier, M. J., De Bruin, M. L., Kalkman, C. J. & Egberts, T. C. G., Jan 2014, In: Journal of Clinical Psychiatry. 75, 1, p. 15-21 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Serotonin Uptake Inhibitors 100%
  • Elderly 61%
  • Cross-Sectional Studies 59%
  • Population 35%
  • Paroxetine 19%
  15 Citations (Scopus)

• Quality of drug label information on QT interval prolongation

  Warnier, M. J., Holtkamp, F. A., Rutten, F. H., Hoes, A. W., de Boer, A., Mol, P. G. M. & De Bruin, M. L., 2014, In: International Journal of Risk and Safety in Medicine. 26, 2, p. 89-98 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • drug 100%
  • Pharmaceutical Preparations 61%
  10 Citations (Scopus)

• Resting heart rate is a risk factor for mortality in chronic obstructive pulmonary disease, but not for exacerbations or pneumonia

  Warnier, M. J., Rutten, F. H., de Boer, A., Hoes, A. W. & De Bruin, M. L., 26 Aug 2014, In: P L o S One. 9, 8, p. e105152

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Heart Rate 100%
  • chronic obstructive pulmonary disease 98%
  • Pulmonary diseases 92%
  • pneumonia 88%
  • Risk Factors 85%
  14 Citations (Scopus)

• Risk management plans as a tool for proactive pharmacovigilance: a cohort study of newly approved drugs in Europe

  Vermeer, N. S., Duijnhoven, R. G., Straus, S. M. J. M., Mantel-Teeuwisse, A. K., Arlett, P. R., Egberts, A. C. G., Leufkens, H. G. M. & De Bruin, M. L., 15 Sept 2014, In: Clinical Pharmacology and Therapeutics. 96, 6, p. 723-31 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Pharmacovigilance 100%
  • Risk Management 84%
  • Uncertainty 70%
  • Cohort Studies 52%
  • Pharmaceutical Preparations 31%
  19 Citations (Scopus)

• Safety information on QT-interval prolongation: comparison of European Union and United States drug labeling

  Warnier, M. J., Holtkamp, F. A., Rutten, F. H., Hoes, A. W., de Boer, A., Mol, P. G. M. & De Bruin, M. L., Sept 2014, In: Drug Discovery Today. 19, 9, p. 1294-7 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • QT Interval 100%
  • Safety Property 82%
  • Drug Labeling 74%
  • European Union 58%
  • Label 44%
  3 Citations (Scopus)

• The Costs and Effects of Post-Authorisation Safety Studies For New Active Substances

  Bouvy, J. C., De Bruin, M. L., Hoekman, J. & Stolk, P., Nov 2014, In: Value in Health. 17, 7, p. A445-6

  Research output: Contribution to journal › Journal article › Research › peer-review

  209 Citations (Scopus)

• The risk of venous thromboembolism in patients with multiple sclerosis: the Clinical Practice Research Datalink

  Peeters, P. J. H. L., Bazelier, M. T., Uitdehaag, B. M. J., Leufkens, H. G. M., De Bruin, M. L. & de Vries, F., Apr 2014, In: Journal of Thrombosis and Haemostasis. 12, 4, p. 444-51 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Venous Thromboembolism 100%
  • Multiple Sclerosis 81%
  • Confidence Intervals 9%
  • Varicose Veins 8%
  • Glucocorticoids 7%
  26 Citations (Scopus)
• 2013

  CARING (CAncer Risk and INsulin analoGues): the association of diabetes mellitus and cancer risk with focus on possible determinants - a systematic review and a meta-analysis

  Starup-Linde, J., Karlstad, O., Eriksen, S. A., Vestergaard, P., Bronsveld, H. K., de Vries, F., Andersen, M., Auvinen, A., Haukka, J., Hjellvik, V., Bazelier, M. T., Boer, A. D., Furu, K. & De Bruin, M. L., Dec 2013, In: Current Drug Safety. 8, 5, p. 296-332 37 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Insulin Derivative 100%
  • Diabetes Mellitus 77%
  • Meta-Analysis 73%
  • Systematic Reviews 72%
  • Insulin 66%
  32 Citations (Scopus)

• Electrocardiographic characteristics of patients with chronic obstructive pulmonary disease

  Warnier, M. J., Rutten, F. H., Numans, M. E., Kors, J. A., Tan, H. L., de Boer, A., Hoes, A. W. & De Bruin, M. L., Feb 2013, In: C O P D. 10, 1, p. 62-71 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Chronic Obstructive Pulmonary Disease 100%
  • Electrocardiography 63%
  • Heart Diseases 11%
  • Respiratory Function Tests 7%
  • Lead 6%
  28 Citations (Scopus)

• Erratum: Intensive glucose control and risk of cancer in patients with type 2 diabetes (Diabetologia DOI: 10.1007/s00125-011-2104-x)

  Stefansdottir, G., Zoungas, S., Chalmers, J. A., Kengne, A. P., Knol, M. J., Leufkens, H. G. M., Patel, A., Woodward, M., Grobbee, D. E. & De Bruin, M. L., Sept 2013, In: Diabetologia. 56, 9, p. 2105-2106 2 p.

  Research output: Contribution to journal › Comment/debate › Research › peer-review

• Incidence of adverse events among healthcare workers following H1N1 Mass immunization in Ghana: a prospective study

  Ankrah, D. N. A., Mantel-Teeuwisse, A. K., De Bruin, M. L., Amoo, P. K., Ofei-Palm, C. N., Agyepong, I. & Leufkens, H. G. M., Apr 2013, In: Drug Safety. 36, 4, p. 259-66 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Mass Vaccination 100%
  • Ghana 88%
  • pandemrix 65%
  • Health Personnel 61%
  • Safety 60%
  3 Citations (Scopus)

• Increased risk of sudden cardiac arrest in obstructive pulmonary disease: a case-control study

  Warnier, M. J., Blom, M. T., Bardai, A., Berdowksi, J., Souverein, P. C., Hoes, A. W., Rutten, F. H., de Boer, A., Koster, R. W., De Bruin, M. L. & Tan, H. L., 6 Jun 2013, In: P L o S One. 8, 6, p. e65638

  Research output: Contribution to journal › Journal article › Research › peer-review

  • pulmonary disease 100%
  • cardiac arrest 93%
  • case-control studies 85%
  • Pulmonary diseases 85%
  • Obstructive Lung Diseases 83%
  13 Citations (Scopus)

• Kankerrisico van biologicals vaststellen? Beperkingen in bruikbaarheid van meta-analyse

  Translated title of the contribution: Research into the risk of malignancy from biologicals: utility of meta-analysis hamperedVermeer, N. S. & De Bruin, M. L., 2013, In: Nederlands Tijdschrift voor Geneeskunde. 157, 6, p. A5884

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Biological Products 100%
  • Meta-Analysis 75%
  • Safety 59%
  • Long Term Adverse Effects 35%
  • Clinical Studies 35%

• Kankerrisico van biologicals vaststellen?

  Translated title of the contribution: Determining cancer risk from biologicals? Limitations in the usefulness of meta-analysisVermeer, N. S. & De Bruin, M. L., 2013, In: Nederlands Tijdschrift voor Geneeskunde. 157, 6, A5884.

  Research output: Contribution to journal › Comment/debate › Research › peer-review

• Number of patients studied prior to approval of new medicines: a database analysis

  Duijnhoven, R. G., Straus, S. M. J. M., Raine, J. M., de Boer, A., Hoes, A. W. & De Bruin, M. L., Mar 2013, In: P L o S Medicine (Online). 10, 3, p. e1001407

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prior Authorization 100%
  • Databases 39%
  • Orphaned Children 22%
  • Safety 12%
  • Medicine 12%
  51 Citations (Scopus)

• Re: nonsteroidal anti-inflammatory drug use, chronic liver disease, and hepatocellular carcinoma

  De Bruin, M. L. & Duijnhoven, R. G., 1 May 2013, In: National Cancer Institute. Journal (Online). 105, 9, p. 667-8 2 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  1 Citation (Scopus)

• Reduced in-hospital survival rates of out-of-hospital cardiac arrest victims with obstructive pulmonary disease

  Blom, M. T., Warnier, M. J., Bardai, A., Berdowski, J., Koster, R. W., Souverein, P. C., Hoes, A. W., Rutten, F. H., de Boer, A., De Bruin, M. L. & Tan, H. L., May 2013, In: Resuscitation. 84, 5, p. 569-74 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Obstructive Lung Diseases 100%
  • Out-of-Hospital Cardiac Arrest 96%
  • Survival Rate 56%
  • Lung Diseases 20%
  • Survival 19%
  15 Citations (Scopus)

• Smoking cessation strategies in patients with COPD

  Warnier, M. J., van Riet, E. E. S., Rutten, F. H., De Bruin, M. L. & Sachs, A. P. E., 1 Mar 2013, In: European Respiratory Journal. 41, 3, p. 727-34 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Smoking Cessation 100%
  • Chronic Obstructive Pulmonary Disease 88%
  • Counseling 67%
  • Pharmacology 39%
  • Systematic Reviews 29%
  33 Citations (Scopus)

• The post hoc use of randomised controlled trials to explore drug associated cancer outcomes: methodological challenges

  Stefansdottir, G., Zoungas, S., Chalmers, J., Knol, M. J., Leufkens, H. G. M., Woodward, M., Patel, A., Grobbee, D. E. & De Bruin, M. L., Dec 2013, In: Current Drug Safety. 8, 5, p. 371-8 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Insulin Derivative 100%
  • Randomized Controlled Trials 66%
  • Drug 51%
  • Pharmaceutical Preparations 40%
  • Neoplasms 31%
  2 Citations (Scopus)

• Traceability of biopharmaceuticals in spontaneous reporting systems: a cross-sectional study in the FDA Adverse Event Reporting System (FAERS) and EudraVigilance databases

  Vermeer, N. S., Straus, S. M. J. M., Mantel-Teeuwisse, A. K., Domergue, F., Egberts, T. C. G., Leufkens, H. G. M. & De Bruin, M. L., Aug 2013, In: Drug Safety. 36, 8, p. 617-25 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Biological Products 100%
  • Cross-Sectional Studies 66%
  • Databases 61%
  • Drug 53%
  • Drug-Related Side Effects and Adverse Reactions 29%
  57 Citations (Scopus)

• Use of insulin and insulin analogs and risk of cancer - systematic review and meta-analysis of observational studies

  Karlstad, O., Starup-Linde, J., Vestergaard, P., Hjellvik, V., Bazelier, M. T., Schmidt, M. K., Andersen, M., Auvinen, A., Haukka, J., Furu, K., de Vries, F. & De Bruin, M. L., Dec 2013, In: Current Drug Safety. 8, 5, p. 333-48 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Insulin Derivative 100%
  • Observational Studies 76%
  • Meta-Analysis 73%
  • Systematic Reviews 72%
  • Insulin 66%
  73 Citations (Scopus)

• Use of metformin and survival of diabetic women with breast cancer

  Peeters, P. J. H. L., Bazelier, M. T., Vestergaard, P., Leufkens, H. G. M., Schmidt, M. K., de Vries, F. & De Bruin, M. L., Dec 2013, In: Current Drug Safety. 8, 5, p. 357-63 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Metformin 100%
  • Breast Neoplasms 44%
  • Survival 38%
  • Antidiabetic Agent 24%
  • Hypoglycemic Agents 20%
  31 Citations (Scopus)

• Use of thiazolidinediones and risk of bladder cancer: disease or drugs?

  Bazelier, M. T., de Vries, F., Vestergaard, P., Leufkens, H. G. M. & De Bruin, M. L., Dec 2013, In: Current Drug Safety. 8, 5, p. 364-70 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Urinary Bladder Diseases 100%
  • Biguanide 97%
  • Thiazolidinediones 85%
  • Urinary Bladder Neoplasms 62%
  • Oral Antidiabetic Agent 52%
  11 Citations (Scopus)
• 2012

  Cardiac arrhythmias in adult patients with asthma

  Warnier, M. J., Rutten, F. H., Kors, J. A., Lammers, J. W. J., de Boer, A., Hoes, A. W. & de Bruin, M. L., Nov 2012, In: Journal of Asthma. 49, 9, p. 942-6 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cardiac Arrhythmias 100%
  • Asthma 91%
  • Tachycardia 62%
  • Polyvinyl Chloride 56%
  • Atrial Flutter 26%
  15 Citations (Scopus)

• Glucose-lowering agents and the patterns of risk for cancer: a study with the General Practice Research Database and secondary care data

  van Staa, T. P., Patel, D., Gallagher, A. M. & de Bruin, M. L., Mar 2012, In: Diabetologia. 55, 3, p. 654-65 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Secondary Care 100%
  • General Practice 80%
  • Glucose 51%
  • Databases 49%
  • Neoplasms 26%
  89 Citations (Scopus)

• Safety learning from drugs of the same class: room for improvement

  Stefansdottir, G., Knol, M. J., Arnardottir, A. H., van der Elst, M. E., Grobbee, D. E., Leufkens, H. G. M. & De Bruin, M. L., May 2012, In: Clinical Pharmacology and Therapeutics. 91, 5, p. 872-80 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Learning 100%
  • Safety 79%
  • Drug-Related Side Effects and Adverse Reactions 63%
  • Pharmaceutical Preparations 56%
  • European Union 12%
  6 Citations (Scopus)
• 2011

  Intensive glucose control and risk of cancer in patients with type 2 diabetes

  Stefansdottir, G., Zoungas, S., Chalmers, J., Kengne, A. P., Knol, M. J., Leufkens, H. G. M., Patel, A., Woodward, M., Grobbee, D. E. & De Bruin, M. L., Jul 2011, In: Diabetologia. 54, 7, p. 1608-14 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Type 2 Diabetes Mellitus 100%
  • Glucose 83%
  • Neoplasms 42%
  • Gliclazide 26%
  • Incidence 17%
  33 Citations (Scopus)

• Randomized controlled trials of COX-2 inhibitors: an analysis of doses used and trends over time to investigate implications for comparative safety

  Stefansdottir, G., De Bruin, M. L., Knol, M. J., Grobbee, D. E. & Leufkens, H. G. M., 1 Sept 2011, In: Drug Safety. 34, 9, p. 783-92 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cyclooxygenase 2 Inhibitor 100%
  • rofecoxib 95%
  • Cyclooxygenase 2 Inhibitors 78%
  • Celecoxib 77%
  • Rofecoxib 73%
  2 Citations (Scopus)