Electrocardiographic characteristics of patients with chronic obstructive pulmonary disease

Miriam J Warnier; Frans H Rutten; Mattijs E Numans; Jan A Kors; Hanno L Tan; Anthonius de Boer; Arno W Hoes; Marie L De Bruin

doi:10.3109/15412555.2012.727918

Electrocardiographic characteristics of patients with chronic obstructive pulmonary disease

Miriam J Warnier, Frans H Rutten, Mattijs E Numans, Jan A Kors, Hanno L Tan, Anthonius de Boer, Arno W Hoes, Marie L De Bruin

28 Citations (Scopus)

Abstract

Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of cardiovascular disease. Electrocardiography (ECG) carries information about cardiac disease and prognosis, but studies comparing ECG characteristics between patients with and without COPD are lacking. We related ECG characteristics of patients with COPD, to ECG characteristics of patients without COPD, and determined whether ECG abnormalities are related to COPD severity. A cross-sectional study was conducted within a cohort of 243 COPD patients, aged 65 years or older. All patients underwent extensive examinations, including resting 12-lead ECG and pulmonary function tests. The reference group (n = 293) was a sample from the general population, also aged 65 or older, without COPD. Abnormal ECGs were more prevalent in COPD patients (50%) than in patients without COPD (36%, p = 0.054). Conduction abnormalities were the most common ECG abnormality in COPD patients (28%) being significantly more prevalent than in patients without COPD (11%, p < 0.001). The mean heart rate was higher in COPD patients (72 bpm (SD 14)) compared to controls (65 bpm (SD 13), p < 0.001), and QTc prolongation was less frequent in COPD patients (9% versus 14%, p = 0.01). The prevalence of ECG abnormalities increased with severity of pulmonary obstruction. ECG abnormalities, especially conduction abnormalities are common in COPD patients, and the prevalence of ECG abnormalities increases with severity of COPD. This underlines the importance of an integrated-care approach for COPD patients, paying attention to early detection of unrecognized coexisting cardiac disorders.

Original language	English
Journal	C O P D
Volume	10
Issue number	1
Pages (from-to)	62-71
Number of pages	10
ISSN	1541-2555
DOIs	https://doi.org/10.3109/15412555.2012.727918
Publication status	Published - Feb 2013
Externally published	Yes

Keywords

Aged
Case-Control Studies
Cross-Sectional Studies
Electrocardiography
Female
Heart
Heart Diseases
Humans
Linear Models
Male
Multivariate Analysis
Odds Ratio
Pulmonary Disease, Chronic Obstructive
Respiratory Function Tests
Risk Assessment
Severity of Illness Index
Journal Article
Research Support, Non-U.S. Gov't

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3109/15412555.2012.727918

Cite this

@article{db696a1defed42c18298ffe3b119af8a,

title = "Electrocardiographic characteristics of patients with chronic obstructive pulmonary disease",

abstract = "Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of cardiovascular disease. Electrocardiography (ECG) carries information about cardiac disease and prognosis, but studies comparing ECG characteristics between patients with and without COPD are lacking. We related ECG characteristics of patients with COPD, to ECG characteristics of patients without COPD, and determined whether ECG abnormalities are related to COPD severity. A cross-sectional study was conducted within a cohort of 243 COPD patients, aged 65 years or older. All patients underwent extensive examinations, including resting 12-lead ECG and pulmonary function tests. The reference group (n = 293) was a sample from the general population, also aged 65 or older, without COPD. Abnormal ECGs were more prevalent in COPD patients (50%) than in patients without COPD (36%, p = 0.054). Conduction abnormalities were the most common ECG abnormality in COPD patients (28%) being significantly more prevalent than in patients without COPD (11%, p < 0.001). The mean heart rate was higher in COPD patients (72 bpm (SD 14)) compared to controls (65 bpm (SD 13), p < 0.001), and QTc prolongation was less frequent in COPD patients (9% versus 14%, p = 0.01). The prevalence of ECG abnormalities increased with severity of pulmonary obstruction. ECG abnormalities, especially conduction abnormalities are common in COPD patients, and the prevalence of ECG abnormalities increases with severity of COPD. This underlines the importance of an integrated-care approach for COPD patients, paying attention to early detection of unrecognized coexisting cardiac disorders.",

keywords = "Aged, Case-Control Studies, Cross-Sectional Studies, Electrocardiography, Female, Heart, Heart Diseases, Humans, Linear Models, Male, Multivariate Analysis, Odds Ratio, Pulmonary Disease, Chronic Obstructive, Respiratory Function Tests, Risk Assessment, Severity of Illness Index, Journal Article, Research Support, Non-U.S. Gov't",

author = "Warnier, {Miriam J} and Rutten, {Frans H} and Numans, {Mattijs E} and Kors, {Jan A} and Tan, {Hanno L} and {de Boer}, Anthonius and Hoes, {Arno W} and {De Bruin}, {Marie L}",

year = "2013",

month = feb,

doi = "10.3109/15412555.2012.727918",

language = "English",

volume = "10",

pages = "62--71",

journal = "COPD: Journal of Chronic Obstructive Pulmonary Disease",

issn = "1541-2555",

publisher = "Taylor & Francis",

number = "1",

}

TY - JOUR

T1 - Electrocardiographic characteristics of patients with chronic obstructive pulmonary disease

AU - Warnier, Miriam J

AU - Rutten, Frans H

AU - Numans, Mattijs E

AU - Kors, Jan A

AU - Tan, Hanno L

AU - de Boer, Anthonius

AU - Hoes, Arno W

AU - De Bruin, Marie L

PY - 2013/2

Y1 - 2013/2

N2 - Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of cardiovascular disease. Electrocardiography (ECG) carries information about cardiac disease and prognosis, but studies comparing ECG characteristics between patients with and without COPD are lacking. We related ECG characteristics of patients with COPD, to ECG characteristics of patients without COPD, and determined whether ECG abnormalities are related to COPD severity. A cross-sectional study was conducted within a cohort of 243 COPD patients, aged 65 years or older. All patients underwent extensive examinations, including resting 12-lead ECG and pulmonary function tests. The reference group (n = 293) was a sample from the general population, also aged 65 or older, without COPD. Abnormal ECGs were more prevalent in COPD patients (50%) than in patients without COPD (36%, p = 0.054). Conduction abnormalities were the most common ECG abnormality in COPD patients (28%) being significantly more prevalent than in patients without COPD (11%, p < 0.001). The mean heart rate was higher in COPD patients (72 bpm (SD 14)) compared to controls (65 bpm (SD 13), p < 0.001), and QTc prolongation was less frequent in COPD patients (9% versus 14%, p = 0.01). The prevalence of ECG abnormalities increased with severity of pulmonary obstruction. ECG abnormalities, especially conduction abnormalities are common in COPD patients, and the prevalence of ECG abnormalities increases with severity of COPD. This underlines the importance of an integrated-care approach for COPD patients, paying attention to early detection of unrecognized coexisting cardiac disorders.

AB - Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of cardiovascular disease. Electrocardiography (ECG) carries information about cardiac disease and prognosis, but studies comparing ECG characteristics between patients with and without COPD are lacking. We related ECG characteristics of patients with COPD, to ECG characteristics of patients without COPD, and determined whether ECG abnormalities are related to COPD severity. A cross-sectional study was conducted within a cohort of 243 COPD patients, aged 65 years or older. All patients underwent extensive examinations, including resting 12-lead ECG and pulmonary function tests. The reference group (n = 293) was a sample from the general population, also aged 65 or older, without COPD. Abnormal ECGs were more prevalent in COPD patients (50%) than in patients without COPD (36%, p = 0.054). Conduction abnormalities were the most common ECG abnormality in COPD patients (28%) being significantly more prevalent than in patients without COPD (11%, p < 0.001). The mean heart rate was higher in COPD patients (72 bpm (SD 14)) compared to controls (65 bpm (SD 13), p < 0.001), and QTc prolongation was less frequent in COPD patients (9% versus 14%, p = 0.01). The prevalence of ECG abnormalities increased with severity of pulmonary obstruction. ECG abnormalities, especially conduction abnormalities are common in COPD patients, and the prevalence of ECG abnormalities increases with severity of COPD. This underlines the importance of an integrated-care approach for COPD patients, paying attention to early detection of unrecognized coexisting cardiac disorders.

KW - Aged

KW - Case-Control Studies

KW - Cross-Sectional Studies

KW - Electrocardiography

KW - Female

KW - Heart

KW - Heart Diseases

KW - Humans

KW - Linear Models

KW - Male

KW - Multivariate Analysis

KW - Odds Ratio

KW - Pulmonary Disease, Chronic Obstructive

KW - Respiratory Function Tests

KW - Risk Assessment

KW - Severity of Illness Index

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.3109/15412555.2012.727918

DO - 10.3109/15412555.2012.727918

M3 - Journal article

C2 - 23413894

SN - 1541-2555

VL - 10

SP - 62

EP - 71

JO - COPD: Journal of Chronic Obstructive Pulmonary Disease

JF - COPD: Journal of Chronic Obstructive Pulmonary Disease

IS - 1

ER -

Electrocardiographic characteristics of patients with chronic obstructive pulmonary disease

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this