Kristian Linnet

2020

Treatment Status and Use of Psychoactive Substances in Deceased Drug Users

Kruckow, L., Tjagvad, C., Clausen, T., Linnet, K. & Banner, J., 1 Mar 2020, In: European Addiction Research. p. 1-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2019

Analytical and Clinical Evaluation of Methods

Linnet, K., Moons, K. G. M. & Boyd, J. C., 2019, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics. Rifai, N. (ed.). 8 ed. Elsevier, p. 7-37

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Application of an activity‐based receptor bioassay to investigate the in vitro activity of selected indole‐ and indazole‐3‐carboxamide‐based synthetic cannabinoids at CB1 and CB2 receptors

Noble, C., Cannaert, A., Linnet, K. & Stove, C. P., Mar 2019, In: Drug Testing and Analysis. 11, 3, p. 501-511

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

Brain-blood ratio of morphine in heroin and morphine autopsy cases

Nedahl, M., Johansen, S. S. & Linnet, K., 1 Aug 2019, In: Forensic Science International. 301, p. 388-393

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1

Briand, E., Thomsen, R., Linnet, K., Rasmussen, H. B., Brunak, S. & Taboureau, O., 29 Jul 2019, In: Molecules. 24, 15, 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

26 Downloads (Pure)

Comprehensive investigation on synthetic cannabinoids: Metabolic behavior and potency testing, using 5F-APP-PICA and AMB-FUBINACA as model compounds

Fabregat-Safont, D., Mardal, M., Noble, C., Cannaert, A., Stove, C. P., Sancho, J. V., Linnet, K., Hernández, F. & Ibáñez, M., 1 Sept 2019, In: Drug Testing and Analysis. 11, 9, p. 1358-1368

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Coronary artery CT calcium score assessed by direct calcium quantification using atomic absorption spectroscopy and compared to macroscopic and histological assessments

Gheorghe, A. G., Jacobsen, C., Thomsen, R., Linnet, K., Lynnerup, N., Andersen, C. B., Fuchs, A., Kofoed, K. F. & Banner, J., 1 Sept 2019, In: International Journal of Legal Medicine. 133, 5, p. 1485–1496

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Corrigendum to: highResNPS.com: An Online Crowd-Sourced HR-MS Database for Suspect and Non-targeted Screening of New Psychoactive Substances (Journal of Analytical Toxicology (2019) (1-8) DOI: 10.1093/jat/bkz030)

Mardal, M., Andreasen, M. F., Mollerup, C. B., Stockham, P., Telving, R., Thomaidis, N. S., Diamanti, K. S., Linnet, K. & Dalsgaard, P. W., 24 Jul 2019, In: Journal of Analytical Toxicology. 43, 6, p. E7-E8

Research output: Contribution to journal › Comment/debate › Research › peer-review

Effects of glucagon-like peptide 1 analogs on alcohol intake in alcohol-preferring vervet monkeys

Thomsen, M., Holst, J. J., Molander, A., Linnet, K., Ptito, M. & Fink-Jensen, A., 14 Feb 2019, In: Psychopharmacology. 236, 2, p. 603–611

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Glycine‐modified growth hormone secretagogues identified in seized doping material

Gajda, P. M., Holm, N. B., Hoej, L. J., Rasmussen, B. S., Dalsgaard, P. W., Reitzel, L. A. & Linnet, K., 1 Feb 2019, In: Drug Testing and Analysis. 11, 2, p. 350-354

Research output: Contribution to journal › Letter › peer-review

6 Citations (Scopus)

HighResNPS.com: An Online Crowd-Sourced HR-MS Database for Suspect and Non-targeted Screening of New Psychoactive Substances

Mardal, M., Andreasen, M. F., Mollerup, C. B., Stockham, P., Telving, R., Thomaidis, N. S., Diamanti, K. S., Linnet, K. & Dalsgaard, P. W., 16 May 2019, In: Journal of Analytical Toxicology. 43, 7, p. 520-527

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

17 Downloads (Pure)

Identification of phenobarbital and other barbiturates in forensic drug screening using positive electrospray ionization liquid chromatography−high resolution mass spectrometry

Høj, L. J., Mollerup, C. B., Rasmussen, B. S., Johansen, S. S., Linnet, K. & Dalsgaard, P. W., Aug 2019, In: Drug Testing and Analysis. 11, 8, p. 1258-1263

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

In Vitro Metabolism and Hepatic Intrinsic Clearance of the Synthetic Cannabinoid Receptor Agonist JWH-122 and Its Four ω-Halogenated Analogues

Davidsen, A. B., Mardal, M. & Linnet, K., 1 Jul 2019, In: The AAPS Journal. 21, p. 1-9 63.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Postmortem Brain-Blood Ratios of Amphetamine, Cocaine, Ephedrine, MDMA and Methylphenidate

Nedahl, M., Johansen, S. S. & Linnet, K., 1 Jun 2019, In: Journal of Analytical Toxicology. 43, 5, p. 378–384

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels

Madsen, M. K., Fisher, P. M., Burmester, D., Dyssegaard, A., Stenbæk, D. S., Kristiansen, S., Johansen, S. S., Lehel, S., Linnet, K., Svarer, C., Erritzoe, D., Ozenne, B. & Knudsen, G. M., 1 Jun 2019, In: Neuropsychopharmacology. 44, p. 1328-1334

Research output: Contribution to journal › Journal article › Research › peer-review

48 Citations (Scopus)

Retrospective analysis for valproate screening targets with liquid chromatography-high resolution mass spectrometry with positive electrospray ionization: An omics-based approach

Mollerup, C. B., Rasmussen, B. S., Johansen, S. S., Mardal, M., Linnet, K. & Dalsgaard, P. W., May 2019, In: Drug Testing and Analysis. 11, 5, p. 730-738

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Segmental Hair Analysis-Interpretation of the Time of Drug Intake in Two Patients Undergoing Drug Treatment

Wang, X., Johansen, S. S., Nielsen, M. K. K. & Linnet, K., May 2019, In: Journal of Forensic Sciences. 64, 3, p. 950-955

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

2018

Application of a screening method for fentanyl and its analogues using UHPLC-QTOF-MS with data-independent acquisition (DIA) in MS^E mode and retrospective analysis of authentic forensic blood samples

Noble, C., Dalsgaard, P. W., Johansen, S. S. & Linnet, K., Apr 2018, In: Drug Testing and Analysis. 10, 4, p. 651-662

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

Bromo-dragonfly, a psychoactive benzodifuran, is resistant to hepatic metabolism and potently inhibits monoamine oxidase A

Noble, C., Holm, N. B., Mardal, M. & Linnet, K., 1 Oct 2018, In: Toxicology Letters. 295, p. 397-407

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Driving under the influence of alcohol and drugs in the eastern part of Denmark in 2015 and 2016: Abuse patterns and trends

Simonsen, K. W., Linnet, K. & Rasmussen, B. S., 4 Jul 2018, In: Traffic Injury Prevention. 19, 5, p. 468-475

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Fatal intoxications among non-drug addicts in Eastern Denmark over a 5-year period (2008–2012)

Johansen, S. S., Jacobsen, C. & Linnet, K., 4 Dec 2018, In: Research and Reports in Forensic Medical Science. 8, p. 9—16

Research output: Contribution to journal › Journal article › Research › peer-review

51 Downloads (Pure)

Hair analysis in toxicological investigation of drug-facilitated crimes in Denmark over a 8-year period

Wang, X., Johansen, S. S., Nielsen, M. K. K. & Linnet, K., 1 Apr 2018, In: Forensic Science International. 285, p. e1-e12 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Metabolism of the synthetic cannabinoid 5F-PY-PICA by human and rat hepatocytes and identification of biliary analytical targets by directional efflux in sandwich-cultured rat hepatocytes using UHPLC-HR-MS/MS

Mardal, M., Annaert, P., Noble, C., Oorts, M. & Linnet, K., 5 Feb 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 149, p. 296-307 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Metabolism of the synthetic cannabinoids AMB-CHMICA and 5C-AKB48 in pooled human hepatocytes and rat hepatocytes analyzed by UHPLC-(IMS)-HR-MS^E

Mardal, M., Dalsgaard, P. W., Qi, B., Mollerup, C. B., Annaert, P. & Linnet, K., 15 Apr 2018, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1083, p. 189-197 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Metabolite Profiling of Methoxyacetylfentanyl in Pooled Human Hepatocytes and Quantitation in Biological Samples from a Postmortem Forensic Case

Mardal, M., Johansen, S. S., Davidsen, A. B., Dalsgaard, P. W. & Linnet, K., 28 Aug 2018.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate

Kaddurah-Daouk, R., Hankemeier, T., Scholl, E. H., Baillie, R., Harms, A., Stage, C., Dalhoff, K. P., Jűrgens, G., Taboureau, O., Nzabonimpa, G. S., Motsinger-Reif, A. A., Thomsen, R., Linnet, K., Rasmussen, H. B., INDICES Consortium & Pharmacometabolomics Research Network, 1 Aug 2018, In: CPT: Pharmacometrics and Systems Pharmacology. 7, 8, p. 525-533 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Postmortem analysis of three methoxyacetylfentanyl-related deaths in Denmark and in vitro metabolite profiling in pooled human hepatocytes

Mardal, M., Johansen, S. S., Davidsen, A. B., Telving, R., Jornil, J. R., Dalsgaard, P. W., Hasselstrøm, J. B., Øiestad, Å. M., Linnet, K. & Andreasen, M. F., Sept 2018, In: Forensic Science International. 290, p. 310-317

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Post-mortem quetiapine concentrations in hair segments of psychiatric patients - Correlation between hair concentration, dose and concentration in blood

Günther, K. N., Johansen, S. S., Nielsen, M. K. K., Wicktor, P., Banner, J. & Linnet, K., Apr 2018, In: Forensic Science International. 285, p. 58-64 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Post-mortem toxicology in young sudden cardiac death victims: A nationwide cohort study

Bjune, T., Risgaard, B., Kruckow, L., Glinge, C., Ingemann-Hansen, O., Leth, P. M., Linnet, K., Banner, J., Winkel, B. G. & Tfelt-Hansen, J., 1 Apr 2018, In: Europace. 20, 4, p. 614–621

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Prediction of collision cross section and retention time for broad scope screening in gradient reversed-phase liquid chromatography-ion mobility-high resolution accurate mass spectrometry

Mollerup, C. B., Mardal, M., Dalsgaard, P. W., Linnet, K. & Barron, L. P., 23 Mar 2018, In: Journal of Chromatography A. 1542, p. 82-88

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

Reference Brain/Blood Concentrations of Citalopram, Duloxetine, Mirtazapine and Sertraline

Nedahl, M., Johansen, S. S. & Linnet, K., 1 Apr 2018, In: Journal of Analytical Toxicology. 42, 3, p. 149-156

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Reference Brain and Blood Concentrations of Olanzapine in Postmortem Cases

Nedahl, M., Johansen, S. & Linnet, K., 1 Nov 2018, In: Journal of Analytical Toxicology. 42, 9, p. 650-654 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Segmental Analysis of Chlorprothixene and Desmethylchlorprothixene in Postmortem Hair

Günther, K. N., Johansen, S. S., Wicktor, P., Banner, J. & Linnet, K., 1 Nov 2018, In: Journal of Analytical Toxicology. 42, 9, p. 642-649

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Statistical Methodologies in Laboratory Medicine: Analytical and Clinical Evaluation of Laboratory Tests

Linnet, K., Moons, K. G. M. & Boyd, J. C., 2018, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6 ed. Elsevier, p. 10-60.e5

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review

Validation of a fully automated solid‐phase extraction and ultra‐high‐performance liquid chromatography–tandem mass spectrometry method for quantification of 30 pharmaceuticals and metabolites in post‐mortem blood and brain samples

Nielsen, M. K. K., Nedahl, M., Johansen, S. S. & Linnet, K., Jul 2018, In: Drug Testing and Analysis. 10, 7, p. 1147-1157

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

2017

Advantages of analyzing postmortem brain samples in routine forensic drug screening—case series of three non-natural deaths tested positive for lysergic acid diethylamide (LSD)

Mardal, M., Johansen, S. S., Thomsen, R. & Linnet, K., Sept 2017, In: Forensic Science International. 278, p. e14-e18

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Analytical Profiling of Airplane Wastewater: a New Matrix for Mapping Worldwide Patterns of Drug Use and Abuse

Mardal, M., Aarestrup, F. M., Rasmussen, B. S., Mollerup, C. B., Dalsgaard, P. W. & Linnet, K., 2017, In: Scandinavian Journal of Forensic Science. 23, 1, p. 7-12

Research output: Contribution to journal › Journal article › Research › peer-review

69 Downloads (Pure)

Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH

Nielsen, L. M., Holm, N. B., Leth-Petersen, S., Kristensen, J. L., Olsen, L. & Linnet, K., May 2017, In: Drug Testing and Analysis. 9, 5, p. 671–679

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

Deposition of diazepam and its metabolites in hair following a single dose of diazepam

Wang, X., Johansen, S. S., Zhang, Y., Jia, J., Rao, Y., Jiang, F. & Linnet, K., 1 Jan 2017, In: International Journal of Legal Medicine (Print). 131, 1, p. 131-141 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

In vitro studies on flubromazolam metabolism and detection of its metabolites in authentic forensic samples

Noble, C., Mardal, M., Holm, N. B., Johansen, S. S. & Linnet, K., Aug 2017, In: Drug Testing and Analysis. 9, 8, p. 1182–1191

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

Metabolism of the synthetic cannabinoids AMB-CHMICA and 5C-AKB48 in rat hepatocytes and pooled human hepatocytes analyzed by UHPLC-ion mobility-qTOF

Mardal, M., Dalsgaard, P. W., Qi, B., Annaert, P. & Linnet, K., 27 Oct 2017.

Research output: Contribution to conference › Poster › Research › peer-review

Nomenclature for alleles of the human carboxylesterase 1 gene

INDICES Consortium, 1 Jan 2017, In: Pharmacogenetics and Genomics. 27, 2, p. 78-80 3 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

4 Citations (Scopus)

Postmortem concentrations of gamma-hydroxybutyrate (GHB) in peripheral blood and brain tissue - Differentiating between postmortem formation and antemortem intake

Thomsen, R., Rasmussen, B. S., Johansen, S. S. & Linnet, K., 1 Mar 2017, In: Forensic Science International. 272, p. 154-158

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Targeted analysis of 116 drugs in hair by UHPLC-MS/MS and its application to forensic cases

Wang, X., Johansen, S. S., Nielsen, M. K. K. & Linnet, K., Aug 2017, In: Drug Testing and Analysis. 9, 8, p. 1137–1151

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Targeted and non-targeted drug screening in whole blood by UHPLC-TOF-MS with data-independent acquisition

Mollerup, C. B., Dalsgaard, P. W., Mardal, M. & Linnet, K., Jul 2017, In: Drug Testing and Analysis. 9, 7, p. 1052–1061 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

39 Citations (Scopus)

The significance of sampling time in therapeutic drug monitoring of clozapine

Jakobsen, M. I., Larsen, J. R., Svensson, C. K., Johansen, S. S., Linnet, K., Nielsen, J. & Fink-Jensen, A., 1 Feb 2017, In: Acta Psychiatrica Scandinavica. 135, 2, p. 159-169 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

2016

A case story, involving the use of maltitol, a sugar alcohol, as a cutting agent in amphetamine and cocaine powders

Reitzel, L. A., Holm, N. B., Linnet, K. & Müller, I. B., Jun 2016, In: Scandinavian Journal of Forensic Science. 22, 1, p. 6-10 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

136 Downloads (Pure)

Cytochrome P450-mediated metabolism of the synthetic cannabinoids UR-144 and XLR-11

Nielsen, L. M., Holm, N. B., Olsen, L. & Linnet, K., 1 Aug 2016, In: Drug Testing and Analysis. 8, 8, p. 792–800

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Determination of the unbound fraction of R- and S-methadone in human brain

Holm, K. M. D. & Linnet, K., 1 Nov 2016, In: International Journal of Legal Medicine (Print). 130, 6, p. 1519–1526

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Development of a UPLC–MS/MS method for determining ɣ-hydroxybutyric acid (GHB) and GHB glucuronide concentrations in hair and application to forensic cases

Wang, X., Johansen, S. S. & Linnet, K., 1 Jan 2016, In: Forensic Toxicology. 34, 1, p. 51-60

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Kristian Linnet

Research output

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