Marie Mardal

Short presentation

Min forskning er baseret på detektion af rusmidler i biologiske materialer - i særdeleshed blandede biologiske prøver så som spildevand. Dette indebærer primært metabolismestudier i celle- og/eller dyremodeller som bruges til at identificere hvordan et rusmiddel bliver metaboliseret (omdannet) i kroppen og hvordan det udskilles. Derudover har jeg forsket i mikrobiel biotransformation af rusmidler og rusmiddelmetabolitter for at undersøge rusmidlers stabilitet i spildevandets mikrobielle miljø. Når vi ved hvordan et rusmiddel bliver omdannet og udskilt kan vi lettere måle det i fx urin, spildevand og andet biologisk materiale.

Forskningsområder indebærer

LC-HR-MS/MS

Lægemiddel- og rusmiddelmetabolisme og -disposition

Spildevandsbaseret epidemiologi (wastewater-based epidemiology)

Mikrobial biotransformation ad rusmidler

Toksikokinetik

Short presentation

Maries primary fields of research is drug metabolism, detectability, and disposition in various matrices.

In order to detect, and possibly quantify, drug consumption we need to know which analytical targets to measure, and in which matrices we can measure the targets. This information can be collected through studies involving post-mortem and/or in vitro analyses on drug disposition into the brain and bile together with drug metabolism studies. Additionally, Marie is currently involved in research projects involving analysis of drug consumption trends on community-level using wastewater-based epidemiology, in vitro metabolism studies on new psychoactive substances, and improvement of screening methods using high resolution mass spectrometry.

CV

2018 -        : Tenure-track assistant professor, Section of forensic chemistry, UCPH

2016 - 2018: Scientific assistant/postdoctoral researcher, Section of forensic chemistry, UCPH

2013 - 2016: PhD, EU-funded MSCA ITN 'SEWPROF', Saarland University (Germany)

2012 - 2013: Scientific assistant, AAU BIO

2011          : ERASMUS student, Uppsala University (Sweden)

2010 - 2012: M.Sc. Pharmaceutical Sciences, UCPH

2006 - 2010: B.Sc. Pharmacy, UCPH

2016 - 2018: Management committee member in the EU-funded COST action SCORE-COST (ESSEM 1307)