Johan Gotthardt Olsen

Research output

Research output per year 1998 2001 2009 2011 2015 2016 2018

• 15 Journal article
• 3 Review
• 1 Book chapter

Research output per year

Research output per year

Search results

• 2018

  Structure of radical-induced cell death1 hub domain reveals a common αα-scaffold for disorder in transcriptional networks

  Bugge, K. Ø., Staby, L., Kemplen, K. R., O'Shea, C., Bendsen, S. K., Jensen, M. K., Olsen, J. G., Skriver, K. & Kragelund, B. B., 1 May 2018, In: Structure. 26, 5, p. 734-746 21 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gene Regulatory Networks 100%
  • Disorder 78%
  • TATA-Binding Protein Associated Factors 75%
  • Plant Structures 71%
  • Intrinsically Disordered Proteins 66%
  13 Citations (Scopus)
• 2017

  Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness

  Olsen, J. G., Teilum, K. & Kragelund, B. B., 1 Sept 2017, In: Cellular and Molecular Life Sciences. 74, 17, p. 3175-3183 9 p.

  Research output: Contribution to journal › Review › peer-review

  • Intrinsically Disordered Proteins 100%
  • Post Translational Protein Processing 35%
  • Binding Sites 26%
  • Proteins 25%
  48 Citations (Scopus)

  118 Downloads (Pure)
• 2016

  A combined computational and structural model of the full-length human prolactin receptor

  Bugge, K. Ø., Papaleo, E., Haxholm, G. W., Hopper, J. T. S., Robinson, C. V., Olsen, J. G., Lindorff-Larsen, K. & Kragelund, B. B., 13 May 2016, In: Nature Communications. 7, 11 p., 11578.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prolactin 100%
  • Prolactin Receptors 99%
  • Cytokine Receptors 84%
  • Structural Models 82%
  • Mass Spectrometry 62%
  33 Citations (Scopus)

  125 Downloads (Pure)

• Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template

  Johansson, K. E., Johansen, N. T., Christensen, S., Horowitz, S., Bardwell, J. C. A., Olsen, J. G., Willemoës, M., Lindorff-Larsen, K., Ferkinghoff-Borg, J., Hamelryck, T. W. & Winther, J. R., 23 Oct 2016, In: Journal of Molecular Biology. 428, 21, p. 4361-4377 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Thioredoxins 100%
  • Proteins 29%
  • Escherichia coli Proteins 23%
  • X-Rays 15%
  7 Citations (Scopus)

  80 Downloads (Pure)
• 2015

  Globular and disordered-the non-identical twins in protein-protein interactions

  Teilum, K., Olsen, J. G. & Kragelund, B. B., 9 Jul 2015, In: Frontiers in Bioscience. 2, 6 p., 40.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Protein 100%
  • Proteins 89%
  • Intrinsically Disordered Proteins 88%
  • Thermodynamics 73%
  • Inosine Diphosphate 50%
  18 Citations (Scopus)

  96 Downloads (Pure)

• Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes

  Haxholm, G. W., Nikolajsen, L. F., Olsen, J. G., Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, S. H. F., Brooks, A. J., Waters, M. J. & Kragelund, B. B., 15 Jun 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Growth Hormone 100%
  • Cytokine Receptors 93%
  • Immunoreceptor Tyrosine-Based Activation Motif 82%
  • Prolactin Receptors 73%
  • Somatotropin Receptors 72%
  39 Citations (Scopus)
• 2014

  Who climbs the tryptophan ladder? On the structure and function of the WSXWS motif in cytokine receptors and thrombospondin repeats

  Olsen, J. G. & Kragelund, B. B., Jun 2014, In: Cytokine & Growth Factor Reviews. 25, 3, p. 337-341 5 p.

  Research output: Contribution to journal › Review › peer-review

  • Thrombospondins 100%
  • Cytokine Receptors 88%
  • Tryptophan 77%
  • Ligands 51%
  • Amino Acid Motifs 46%
  13 Citations (Scopus)
• 2012

  The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor

  Dagil, R., Knudsen, M. J., Olsen, J. G., O'Shea, C., Franzmann, M., Goffin, V., Teilum, K., Breinholt, J. & Kragelund, B. B., 8 Feb 2012, In: Structure. 20, 2, p. 270-282 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prolactin 100%
  • Prolactin Receptors 99%
  • Cytokine Receptors 84%
  • Dimerization 39%
  • Hormones 36%
  45 Citations (Scopus)
• 2011

  Development of prolactin receptor antagonists with reduced pH-dependence of receptor binding.

  Hansen, M. J. K., Olsen, J. G., Bernichtein, S., O'Shea, C., Sigurskjold, B. W., Goffin, V. & Kragelund, B. B., Jul 2011, In: Journal of Molecular Recognition. 24, 4, p. 533-547 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prolactin Receptors 100%
  • Histidine 64%
  • Prolactin 46%
  • Hormones 16%
  • Calorimetry 16%
  7 Citations (Scopus)

• Protein stability, flexibility and function

  Teilum, K., Olsen, J. G. & Kragelund, B. B., Aug 2011, In: B B A - Proteins and Proteomics. 1814, 8, p. 969-76 8 p.

  Research output: Contribution to journal › Review › peer-review

  • Protein Stability 100%
  • Flexibility 67%
  • Protein 34%
  • Proteins 31%
  • Ligands 29%
  133 Citations (Scopus)

• Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin

  Meinert Niclasen, L., Olsen, J. G., Dagil, R., Qing, Z., Sørensen, O. E. & Kragelund, B. B., 15 Feb 2011, In: Biochemical Journal. 434, 1, p. 123-32 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Exotoxin 100%
  • Exotoxins 85%
  • Trypsin Inhibitor 76%
  • Coagulation 21%
  • erythrogenic toxin 21%
  7 Citations (Scopus)
• 2009

  Functional aspects of protein flexibility

  Teilum, K., Olsen, J. G. & Kragelund, B. B., 2009, In: Cellular and Molecular Life Sciences. 66, 14, p. 2231-47 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Proteins 100%
  • Thermodynamics 41%
  • Cell Communication 31%
  • Amino Acid Sequence 31%
  • Ligands 23%
  142 Citations (Scopus)

• Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form

  Olsen, J. G., Dagil, R., Niclasen, L. M., Sørensen, O. E. & Kragelund, B. B., 2009, In: Journal of Molecular Biology. 393, 3, p. 693-703 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Exotoxins 100%
  • Cysteine Proteases 91%
  • Catalytic Domain 66%
  • Dimerization 27%
  • erythrogenic toxin 20%
  13 Citations (Scopus)
• 2001

  Fatty Acid Biosynthesis: Fatty Acid Synthase. Molecular aspects of β-ketoacyl synthase (KAS) catalysis.

  von Wettstein-Knowles, P., Olsen, J. G., McGuire, K. A. & Larsen, S., 2001, In: Biochemical Society. 28, p. 601-607

  Research output: Contribution to journal › Journal article › Research › peer-review

• Structures of β-Ketoacyl-Acyl Carrier Protein Synthase I Complexed with Fatty Acids Elucidate its Catalytic Machinery

  Olsen, J. G., Kadziola, A., von Wettstein-Knowles, P., Siggaard-Andersen, M. & Larsen, S., 2001, In: Structure. 9, p. 233-243

  Research output: Contribution to journal › Journal article › Research › peer-review

• Β-Ketoacyl - (Acyl Carrier Protein) Synthase I of Escherichia coli: Aspects of the Condensation Mechanism Revealed by Analyses of Mutations in the Active Site Pocket

  McGuire, K. A., Siggaard-Andersen, M., Bangera, M. G., Olsen, J. G. & Wettstein-Knowles, P. V., 2001, In: Biochemistry. 40(33), p. 9836-9845

  Research output: Contribution to journal › Journal article › Research › peer-review
• 2000

  Molecular aspects of beta-ketoacyl synthase (KAS) catalysis

  Wettstein-Knowles, P. V., Olsen, J. G., Mcguire, K. A. & Larsen, S., 2000, In: Biochem. Soc. Trans.. 28, p. 601-607

  Research output: Contribution to journal › Journal article › Research › peer-review
• 1999

  The X-ray crystal structure of β-ketoacyl [acyl carrier protein] sinthase I

  Olsen, J. G., Kadziola, A., Wettstein-Knowles, P. V., Siggaard-Andersen, M., Lindquist, Y. & Larsen, S., 1999, In: FEBS Letters. 460, p. 46-52

  Research output: Contribution to journal › Journal article › Research › peer-review
• 1998

  Defining the functions of highly conserved residues in beta-ketoacyl-ACP synthases

  Siggaard-Andersen, M., Bangera, G., Olsen, J. G. & Wettstein-Knowles, P. V., 1998, Advances in Plant Lipid Research. Spain: Universidad de Sevilla, p. 67-70

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research