Research output per year
Research output per year
Personal profile
CV
Education:
2013 : Ph.D, Structural Biology and NMR Laboratory, the Department of Biology, University of Copenhagen. Ph.D. grant awarded by the Oticon Foundation.
2008 : M.Sc. Chemistry, the Deparment of Chemistry, University of Copenhagen
Ohter positions:
2017- : Post Doc, Team VAR2CSA, ISIM, University of Copenhagen
2015-17: Post Doc, University College London, UK
2014-15 : Post Doc, team VAR2CSA, ISIM, University of Copenhagen
Short presentation
In the VAR2CSA team I am involved in protein production, protein conjugation experiments and development within upstream/downstream processes to optimize production of recombinant malaria protein for use in in vitro and in vivo experiments.
During my education I have worked with proteins, focused on studying their structural and functional relationship and characterising the atomic details of their ligand interaction. The main tool for this has been NMR spectroscopy; however, I have also worked with crystallography, molecular modeling, binding kinetics measured by Attana and isothermal titration calorimetry.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- Faculty of Science
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Dive into the research topics where Robert Dagil is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Research output
- 8 Journal article
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IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties
Dagil, R., Ball, N. J., Ogrodowicz, R. W., Hobor, F., Purkiss, A. G., Kelly, G., Martin, S. R., Taylor, I. A. & Ramos, A., 7 May 2019, In: Nucleic Acids Research. 47, 8, p. 4334-4348 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein
Salanti, A., Clausen, T. M., Agerbæk, M. Ø., Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, T., Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, R., & 15 others, 12 Oct 2015, In: Cancer Cell. 28, 4, p. 500-14 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin
Dagil, R., O'Shea, C., Nykjær, A., Bonvin, A. M. J. J. & Kragelund, B. B., 8 Feb 2013, In: The Journal of Biological Chemistry. 288, 6, p. 4424-35 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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New horizons for lipoprotein receptors: communication by β-propellers
Andersen, O. M., Dagil, R. & Kragelund, B. B., Oct 2013, In: Journal of Lipid Research. 54, p. 2763-2774 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor
Dagil, R., Knudsen, M. J., Olsen, J. G., O'Shea, C., Franzmann, M., Goffin, V., Teilum, K., Breinholt, J. & Kragelund, B. B., 8 Feb 2012, In: Structure. 20, 2, p. 270-282 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin
Meinert Niclasen, L., Olsen, J. G., Dagil, R., Qing, Z., Sørensen, O. E. & Kragelund, B. B., 15 Feb 2011, In: Biochemical Journal. 434, 1, p. 123-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form
Olsen, J. G., Dagil, R., Niclasen, L. M., Sørensen, O. E. & Kragelund, B. B., 2009, In: Journal of Molecular Biology. 393, 3, p. 693-703 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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On the use of pseudocontact shifts in the structure determination of metalloproteins
Jensen, M. R., Hansen, D. F., Ayna, U., Dagil, R., Hass, S. A. M., Christensen, H. E. M. & Led, J. J., 2006, In: Magnetic Resonance in Chemistry. 44, 3, p. 294-301 7 p.Research output: Contribution to journal › Journal article › Research › peer-review