Helle Krogh Johansen

2014

Voriconazole versus amphotericin B or fluconazole in cancer patients with neutropenia

Jørgensen, K. J., Gøtzsche, P. C., Dalbøge, C. S. & Johansen, H. K., 24 Feb 2014, In: Cochrane Database of Systematic Reviews. 2, p. 1-17 17 p.

Research output: Contribution to journal › Review › peer-review

8 Citations (Scopus)

2013

A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF

Dalbøge, C. S., Pressler, T., Høiby, N., Nielsen, K. G. & Johansen, H. K., Jan 2013, In: Journal of Cystic Fibrosis. 12, 1, p. 42-8 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

A novel knee prosthesis model of implant-related osteo- myelitis in rats

Søe, N. H., Jensen, N. V., Nürnberg, B. M., Jensen, A. L., Koch, J., Poulsen, S. S., Pier, G. & Johansen, H. K., Feb 2013, In: Acta Orthopaedica (Print Edition). 84, 1, p. 92-97 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Clinical effects of sinus surgery and adjuvant therapy in cystic fibrosis patients - can chronic lung infections be postponed?

Aanaes, K., Johansen, H. K., Skov, M., Buchvald, F. F., Hjuler, T., Pressler, T., Hoiby, N., Nielsen, K. G. & Buchwald, C. V., 2013, In: Rhinology. 51, 3, p. 222-230 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

Effect of long-term voluntary exercise wheel running on susceptibility to bacterial pulmonary infections in a mouse model

van de Weert-van Leeuwen, P. B., de Vrankrijker, A. M. M., Fentz, J., Ciofu, O., Wojtaszewski, J., Arets, H. G. M., Hulzebos, H. J., van der Ent, C. K., Beekman, J. M. & Johansen, H. K., 23 Feb 2013, In: P L o S One. 8, 12, 7 p., e82869.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

1818 Downloads (Pure)

P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs

Ciofu, O., Johansen, H. K., Aanaes, K., Wassermann, T., Alhede, M., von Buchwald, C. & Høiby, N., Dec 2013, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 12, 6, p. 729-736 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization

Aanaes, K., Johansen, H. K., Poulsen, S. S., Pressler, T., Buchwald, C. & Høiby, N., Jan 2013, In: Journal of Cystic Fibrosis. 12, 1, p. 81-87 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis

Aanaes, K., von Buchwald, C., Hjuler, T., Skov, M., Alanin, M. & Johansen, H. K., Jan 2013, In: American Journal of Rhinology & Allergy. 27, 1, p. e1-4 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

2012

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

Folkesson, A., Jelsbak, L., Yang, L., Johansen, H. K., Ciofu, O., Høiby, N. & Molin, S., Dec 2012, In: Nature Reviews. Microbiology. 10, 12, p. 841-851 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

390 Citations (Scopus)

Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response

Johansen, H. K., Aanaes, K., Pressler, T., Nielsen, K. G., Fisker, J., Skov, M., Høiby, N. & von Buchwald, C., Dec 2012, In: Journal of Cystic Fibrosis. 11, 6, p. 525-531 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

71 Citations (Scopus)

CT of the paranasal sinuses is not a valid indicator for sinus surgery in CF patients

Rasmussen, J., Aanæs, K., Norling, R., Nielsen, K. G., Johansen, H. K. & von Buchwald, C., Mar 2012, In: Journal of Cystic Fibrosis. 11, 2, p. 93-99

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

Hansen, S. K., Rau, M. H., Johansen, H. K., Ciofu, O., Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, K., von Buchwald, C., Høiby, N. & Molin, S., Jan 2012, In: I S M E Journal. 6, 1, p. 31-45

Research output: Contribution to journal › Journal article › Research › peer-review

148 Citations (Scopus)

Extensive endoscopic image-guided sinus surgery decreases BPI-ANCA in patients with cystic fibrosis

Aanaes, K., Rasmussen, N., Pressler, T., Segelmark, M., Johansen, H. K., Lindberg, U., Høiby, N., Carlsson, M., Wieslander, J. & Buchwald, C., Dec 2012, In: Scandinavian Journal of Immunology. 76, 6, p. 573-9 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Initial Pseudomonas aeruginosa infection in patients with cystic fibrosis: characteristics of eradicated and persistent isolates

Tramper-Stranders, G. A., van der Ent, C. K., Molin, S., Yang, L., Hansen, S. K., Rau, M. H., Ciofu, O., Johansen, H. K. & Wolfs, T. F. W., Jun 2012, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 18, 6, p. 567-74 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa

Marvig, R. L., Søndergaard, M. S. R., Damkiær, S., Høiby, N., Johansen, H. K., Molin, S. & Jelsbak, L., Aug 2012, In: Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients

Moskowitz, S. M., Brannon, M. K., Dasgupta, N., Pier, M., Sgambati, N., Miller, A. K., Selgrade, S. E., Miller, S. I., Denton, M., Conway, S. P., Johansen, H. K. & Høiby, N., Feb 2012, In: Antimicrobial Agents and Chemotherapy. 56, 2, p. 1019-1030 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

109 Citations (Scopus)

2011

A prospective survey of Aspergillus spp. in respiratory tract samples: prevalence, clinical impact and antifungal susceptibility

Mortensen, K. L., Johansen, H. K., Fuursted, K., Knudsen, J. D., Gahrn-Hansen, B., Jensen, R. H., Howard, S. & Arendrup, M. C., Nov 2011, In: European Journal of Clinical Microbiology & Infectious Diseases. 30, 11, p. 1355-1363 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

55 Citations (Scopus)

Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance

Mortensen, K. L., Jensen, R. H., Johansen, H. K., Skov, M., Pressler, T., Howard, S. J., Leatherbarrow, H., Mellado, E. & Arendrup, M. C., 1 Jun 2011, In: Journal of Clinical Microbiology. 49, 6, p. 2243-51 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

130 Citations (Scopus)

Biofilm ved kronisk rhinosinuitis og cystisk fibrose

Translated title of the contribution: [Microbial biofilm in rhinosinusitis and cystic fibrosis]Fisker, J., Buchwald, C. V. & Johansen, H. K., 7 Feb 2011, In: Ugeskrift for Laeger. 173, 6, p. 417-9 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis

Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, N. & Johansen, H. K., 1 Sept 2011, In: Journal of Cystic Fibrosis. 10, 5, p. 318-25 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis

Aanæs, K., Rickelt, L. F., Johansen, H. K., von Buchwald, C., Pressler, T., Høiby, N. & Jensen, P. Ø., Mar 2011, In: Journal of Cystic Fibrosis. 10, 2, p. 114-120 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

Diagnostic Issues, Clinical Characteristics, and Outcomes for Patients with Fungemia

Arendrup, M. C., Sulim, S., Holm, A., Nielsen, L., Nielsen, S. D., Knudsen, J. D., Drenck, N. E., Christensen, J. J. & Johansen, H. K., 1 Sept 2011, In: Journal of Clinical Microbiology. 49, 9, p. 3300-8 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

118 Citations (Scopus)

Differentiation of Candida glabrata, C. nivariensis and C. bracarensis based on fragment length polymorphism of ITS1 and ITS2 and restriction fragment length polymorphism of ITS and D1/D2 regions in rDNA

Mirhendi, H., Bruun, B., Schønheyder, H. C., Christensen, J. J., Fuursted, K., Gahrn-Hansen, B., Johansen, H. K., Nielsen, L., Knudsen, J. D. & Arendrup, M. C., Nov 2011, In: European Journal of Clinical Microbiology & Infectious Diseases. 30, p. 1409-1416 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Evolutionary dynamics of bacteria in a human host environment

Yang, L., Jelsbak, L., Marvig, R. L., Damkiær, S., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, H. K., Ciofu, O., Høiby, N., Sommer, M. & Molin, S., 3 May 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-6 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

228 Citations (Scopus)

National surveillance of fungemia in Denmark (2004 to 2009)

Arendrup, M. C., Bruun, B., Christensen, J. J., Fuursted, K., Johansen, H. K., Kjaeldgaard, P., Knudsen, J. D., Kristensen, L., Møller, J., Nielsen, L., Rosenvinge, F. S., Røder, B., Schønheyder, H. C., Thomsen, M. & Truberg, K., 1 Jan 2011, In: Journal of Clinical Microbiology. 49, 1, p. 325-34 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

184 Citations (Scopus)

PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients

Miller, A. K., Brannon, M. K., Stevens, L., Johansen, H. K., Selgrade, S. E., Miller, S. I., Høiby, N. & Moskowitz, S. M., Dec 2011, In: Antimicrobial Agents and Chemotherapy. 55, 12, p. 5761-5769

Research output: Contribution to journal › Journal article › Research › peer-review

119 Citations (Scopus)

Prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia: the value of screening with echocardiography

Rasmussen, R. V., Høst, U., Arpi, M., Hassager, C., Johansen, H. K., Korup, E., Schønheyder, H. C., Berning, J., Gill, S., Rosenvinge, F. S., Fowler, V. G., Møller, J. E., Skov, R. L., Larsen, C. T., Hansen, T. F., Mard, S., Smit, J., Andersen, P. S. & Bruun, N. E., 1 Jun 2011, In: European Journal of Echocardiography. 12, 6, p. 414-20 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

97 Citations (Scopus)

The clinical impact of bacterial biofilms

Høiby, N., Ciofu, O., Johansen, H. K., Song, Z.-J., Moser, C., Jensen, P. Ø., Molin, S., Givskov, M., Tolker-Nielsen, T. & Bjarnsholt, T., Apr 2011, In: International Journal of Oral Science. 3, 2, p. 55-65

Research output: Contribution to journal › Journal article › Research › peer-review

406 Citations (Scopus)

2010

Active immunization against Staphylococcus aureus (oca+) periprosthetic osteomyelitis in rats

Koch, J., Johansen, H. K., Vedel-Jensen, N., Jensen, A., poulsen, S. & Søe, H., 2010. 0 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

Burmølle, M., Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, P., Tvede, M., Nyvad, B., Tolker-Nielsen, T., Givskov, M., Moser, C. E., Kirketerp-Møller, K., Johansen, H. K., Høiby, N., Jensen, P. Ø., Sørensen, S. J. & Bjarnsholt, T., Aug 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.

Research output: Contribution to journal › Review › peer-review

231 Citations (Scopus)

Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection

Hawdon, N. A., Aval, P. S., Barnes, R. J., Gravelle, S. K., Rosengren, J., Khan, S., Ciofu, O., Johansen, H. K., Høiby, N. & Ulanova, M., 1 Jul 2010, In: FEMS Immunology and Medical Microbiology. 59, 2, p. 207-20 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

Chronic infection with Stenotrophomonas maltophilia in patients with cystic fibrosis at the Copenhagen CF centre

Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, N. & Johansen, H. K., 17 Jun 2010. 0 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Diagnosis of bacterial biofilms in chronic sinusitis and pneumonia

Høiby, N., Buchwald, C. V., Aaanæs, K., Pressler, T. & Johansen, H. K., 10 Apr 2010. 0 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts

Rau, M. H., Hansen, S. K., Johansen, H. K., Thomsen, L. E., Workman, C. T., Nielsen, K. F., Jelsbak, L., Høiby, N., Yang, L. & Molin, S., 1 Jun 2010, In: Environmental Microbiology. 12, 6, p. 1643-58 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

93 Citations (Scopus)

Effects of antibiotic treatment of Staphylococcus aureus infection in patients with cystic fibrosis at the Copenhagen CF centre

Dalbøge, C. S., Pressler, T., Høiby, N. & Johansen, H. K., 2010. 0 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Emergence of ESBL-producing Klebsiella pneumoniae in Danish hospitals; this is in part explained by spread of one CTX-M-15 clone in Zealand

Lester, C., Olsen, S., Arpi, R. M., Fuursted, K., Hansen, D. S., Heltberg, O., Holm, A., Højbjerg, T., Jensen, K., Johansen, H. K., Justesen, U., Kemp, M., Knudsen, I. J. D., Røder, B., Frimodt-Møller, N. & Hammerum, A., 2010. 0 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain

Mortensen, K. L., Mellado, E., Lass-Flörl, C., Rodriguez-Tudela, J. L., Johansen, H. K. & Arendrup, M. C., 1 Nov 2010, In: Antimicrobial Agents and Chemotherapy. 54, 11, p. 4545-9 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

177 Citations (Scopus)

Gene transcription profiles of paired mucoid & non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis

Johansen, H. K., Wassermann, T., Alhede, M., Aanæs, K., Buchwald, C. V. & Høiby, N., 2010. 0 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Gene transcription profiles of paired mucoid and non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis

Ciofu, O., Johansen, H. K., Wassermann, T., Aanæs, K., Alhede, M. & Høiby, N., 23 May 2010. 0 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Increased incidence of Mycoplasma pneumoniae infections detected by laboratory-based surveillance in Denmark in 2010

Rasmussen, J., Voldstedlund, M., R L, A., Ellermann-Eriksen, S., Jensen, T. G., Johansen, H. K., Kolmos, B., Mølvadgaard, M., Nielsen, S. S., Olsen, E., Schønning, K. & Uldum, S. A., Nov 2010, In: Eurosurveillance (Online Edition). 15, 45

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

Intravenous alpha-1 antitrypsin augmentation therapy: systematic review

Gøtzsche, P. C. & Johansen, H. K., 1 Sept 2010, In: Danish Medical Bulletin (Online). 57, 9, p. A4175

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease

Gøtzsche, P. C. & Johansen, H. K., 1 Jan 2010, In: Cochrane Database of Systematic Reviews. 7, p. CD007851

Research output: Contribution to journal › Journal article › Research › peer-review

61 Citations (Scopus)

Linezolid in infective endocarditis - it seems to work

Lauridsen, T., Bruun, L., Rasmussen, R., Moser, C. E., Johansen, H. K., Arpi, R. M., Hassager, C. & Bruun, N. E., 2010. 0 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Molecular screening for Candida orthopsilosis and Candida metapsilosis among Danish Candida parapsilosis group blood culture isolates: proposal of a new RFLP profile for differentiation

Mirhendi, H., Bruun, B., Schønheyder, H. C., Christensen, J. J., Fuursted, K., Gahrn-Hansen, B., Johansen, H. K., Nielsen, L., Knudsen, J. D. & Arendrup, M. C., 1 Apr 2010, In: Journal of Medical Microbiology. 59, Pt 4, p. 414-20 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

52 Citations (Scopus)

National Surveillance of Fungaemia in Denmark 2004-2009

Arendrup, M., Christensen, J., Fuursted, K., Johansen, H. K., Kjeldgaard, P., Knudsen, I. J. D., L, K., Møller, J., Nielsen, L., Olesen, L., Rosenvinge, F., Røder, B., Schønheyder, H., Thomsen, M. & Truberg, K., 2010. 0 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients

Høiby, N., Johansen, H. K., Moser, C. E., Ciofu, O., Jensen, P. Ø., Kolpen, M., Lotte, M., Givskov, M., Molin, S. & Bjarnsholt, T., 2010, Biofilm Infections. Bjarnsholt, T., Moser, C. E., Jensen, P. Ø. & Høiby, N. (eds.). 1st ed. New York, NY, US, p. 167-184 17 p.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

The relation of biofilms to chronic otitis media and other ear related chronic infections

Homøe, P. & Johansen, H. K., 2010, Biofilm Infections. Springer Publishing Company

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients

Nørskov-Lauritsen, N., Johansen, H. K., Fenger, M. G., Nielsen, X. C., Pressler, T., Olesen, H. V. & Høiby, N., 1 Aug 2010, In: Journal of Clinical Microbiology. 48, 8, p. 2981-3 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

2009

Håndens akutte infektioner

Translated title of the contribution: Acute infections of the handSøe, N. H., Jensen, N. V., Dahlin, L. & Johansen, H. K., 2009, In: Ugeskrift for læger. 171, 14, p. 1189-93 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media

Homøe, P., Bjarnsholt, T., Wessman, M., Sørensen, H. C. F. & Johansen, H. K., 1 Oct 2009, In: European Archives of Oto-Rhino-Laryngology. 266, 10, p. 1533-8 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

64 Citations (Scopus)

Helle Krogh Johansen

Research output

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