Filip Krag Knop

2014

Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1

Sonne, D. P., Rehfeld, J. F., Holst, J. J., Vilsbøll, T. & Knop, F. K., 1 Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease

Idorn, T., Knop, F. K., Jørgensen, M., Holst, J. J., Hornum, M. & Feldt-Rasmussen, B., Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial

Idorn, T., Knop, F. K., Jorgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, K. B., Holst, J. J., Hornum, M. & Feldt-Rasmussen, B., Sept 2014, In: Diabetologia. 57, 1 supplement, p. S370-S371 909.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

1 Citation (Scopus)

Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): Implications for GLP-1 measurements in clinical studies

Bak, M. J., Albrechtsen, N. J. W., Pedersen, J., Knop, F. K., Vilsbøll Lauritsen, T., Jørgensen, N. B., Hartmann, B., Deacon, C. F., Dragsted, L. O. & Holst, J. J., 1 Nov 2014, In: Diabetes, Obesity and Metabolism. 16, 11, p. 1155-1164 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

56 Citations (Scopus)

The authors reply

Idorn, T., Knop, F. K., Jørgensen, M., Holst, J. J., Hornum, M. & Feldt-Rasmussen, B., Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.

Research output: Contribution to journal › Letter › peer-review

The design and discovery of lixisenatide for the treatment of type 2 diabetes mellitus

Christensen, M., Miossec, P., Larsen, B. D., Werner, U. & Knop, F. K., 1 Oct 2014, In: Expert Opinion on Drug Discovery. 9, 10, p. 1223-1251 29 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

The effects of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes: protocol for a systematic review with meta-analysis of randomised trials

Storgaard, H., Gluud, L. L., Christensen, M., Knop, F. K. & Vilsbøll, T., 2014, In: B M J Open. 4, 8, p. 1-5 5 p., e005378.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

Rhee, N. A., Østoft, S. H., Holst, J. J., Deacon, C., Vilsbøll, T. & Knop, F. K., 1 Sept 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract

Rhee, N. A., Vilmann, P., Hassan, H., Hendel, J. W., Holst, J. J., Vilsbøll, T. & Knop, F. K., Sept 2014, In: Scandinavian Journal of Gastroenterology. 49, 9, p. 1143-1149 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Unprecedented high insulin secretion in a healthy human subject after intravenous glucagon-like peptide-1: a case report

Knop, F. K., Lund, A., Madsbad, S., Holst, J. J., Krarup, T. & Vilsbøll, T., 31 May 2014, In: BMC Research Notes. 7, p. 1-6 6 p., 326.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

2013

Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

Plamboeck, A., Veedfald, S., Deacon, C., Hartmann, B., Wettergren, A., Svendsen, L. B., Meisner, S., Hovendal, C., Knop, F. K., Vilsbøll, T. & Holst, J. J., Aug 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

42 Citations (Scopus)

Effect of the EndoBarrier Gastrointestinal Liner on obesity and type 2 diabetes: protocol for systematic review and meta-analysis of clinical studies

Rohde, U., Hedbäck, N., Gluud, L. L., Vilsbøll, T. & Knop, F. K., 2013, In: B M J Open. 3, 9, p. 1-5 e003417.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Gastrointestinal factors contribute to glucometabolic disturbances in nondiabetic patients with end-stage renal disease

Idorn, T., Knop, F. K., Jørgensen, M., Holst, J. J., Hornum, M. & Feldt-Rasmussen, B., May 2013, In: Kidney International. 83, 5, p. 915-23 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

GLP-1 agonists for type 2 diabetes: pharmacokinetic and toxicological considerations

Jespersen, M. J., Knop, F. K. & Christensen, M., Jan 2013, In: Expert Opinion on Drug Metabolism & Toxicology. 9, 1, p. 17-29 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

Gut microbiota may have influence on glucose and lipid metabolism.

Mikkelsen, K. H., Nielsen, M. F., Tvede, M., Hansen, T., Pedersen, O. B., Holst, J. J., Vilsbøll, T. & Knop, F. K., 11 Nov 2013, In: Ugeskrift for Laeger. 175, 46, p. 2785-2788 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Increased expression of glucagon-like peptide-1 receptors in psoriasis plaques

Faurschou, A., Pedersen, J., Gyldenløve, M., Poulsen, S. S., Holst, J. J., Thyssen, J. P., Zachariae, C., Vilsbøll, T., Skov, L. & Knop, F. K., Feb 2013, In: Experimental Dermatology. 22, 2, p. 150-2 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele

Faerch, K., Pilgaard, K., Knop, F. K., Hansen, T., Pedersen, O., Jørgensen, T. & Holst, J. J., Jan 2013, In: Diabetes, Obesity and Metabolism Online. 15, 1, p. 91-95 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Mechanisms of the incretin effect in subjects with normal glucose tolerance and patients with type 2 diabetes

Mari, A., Bagger, J. I., Ferrannini, E., Holst, J. J., Knop, F. K. & Vilsbøll, T., 3 Sept 2013, In: PLOS ONE. 8, 9, p. e73154

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients

Sonne, D. P., Hare, K. J., Martens, P., Rehfeld, J. F., Holst, J. J., Vilsbøll, T. & Knop, F. K., 15 Feb 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 4, p. G413-9 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Preserved postprandial GLP-1 and GIP responses in patients with maturity onset diabetes of the young

Bagger, J. I., Ostoft, S. H., Hansen, T., Pedersen, O., Holst, J. J., Knop, F. K. & Vilsboll, T., 2013, In: Diabetologia. 56, p. S152-S152

Research output: Contribution to journal › Journal article › Research › peer-review

Psoriasis er associeret med type 2-diabetes

Gyldenl�ve, M., Knop, F. K., Vilsb�ll, T., Zachariae, C. & Skov, L., 4 Mar 2013, In: Ugeskrift for Laeger. 175, 10, p. 652-4 3 p., 652.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Reduced postprandial GLP-1 responses in women with gestational diabetes mellitus

Bonde, L., Vilsbøll, T., Nielsen, T., Bagger, J. I., Svare, J. A., Holst, J. J., Larsen, S. & Knop, F. K., Aug 2013, In: Diabetes, Obesity and Metabolism. 15, 8, p. 713-720 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded, parallel intervention study

Idorn, T., Knop, F. K., Jørgensen, M., Jensen, T., Resuli, M., Hansen, P. M., Christensen, K. B., Holst, J. J., Hornum, M. & Feldt-Rasmussen, B., 26 Apr 2013, In: B M J Open. 3, 4, p. 1-10 11 p., e002764.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Secretion of glucagon-like peptide-1 in patients with type 2 diabetes mellitus: systematic review and meta-analyses of clinical studies

Calanna, S., Christensen, M., Holst, J. J., Laferrère, B., Gluud, L. L., Vilsbøll, T. & Knop, F. K., May 2013, In: Diabetologia. 56, 5, p. 965-72 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

155 Citations (Scopus)

Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies

Calanna, S., Christensen, M., Holst, J. J., Laferrère, B., Gluud, L. L., Vilsbøll, T. & Knop, F. K., Oct 2013, In: Diabetes Care. 36, 10, p. 3346-52 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

91 Citations (Scopus)

Sustained weight loss after treatment with a glucagon-like Peptide-1 receptor agonist in an obese patient with schizophrenia and type 2 diabetes

Ishøy, P. L., Knop, F. K., Lauritsen, T. V., Glenthøj, B. Y. & Ebdrup, B. H., 1 Jun 2013, In: American Journal of Psychiatry. 170, 6, p. 681-682 2 p.

Research output: Contribution to journal › Comment/debate › Communication

20 Citations (Scopus)

The effect of a glucagon-like peptide-1 receptor agonist on glucose tolerance in women with previous gestational diabetes mellitus: protocol for an investigator-initiated, randomised, placebo-controlled, double-blinded, parallel intervention trial

Foghsgaard, S., Vedtofte, L., Mathiesen, E. R., Svare, J. A., Gluud, L. L., Holst, J. J., Damm, P., Knop, F. K. & Vilsbøll, T., 2013, In: B M J Open. 3, 10, p. 1-8 9 p., e003834.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty

Plamboeck, A., Veedfald, S., Deacon, C. F., Hartmann, B., Wettergren, A., Svendsen, L. B., Meisner, S., Hovendahl, C., Vilsboll, T., Knop, F. K. & Holst, J. J., 16 Jun 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

94 Citations (Scopus)

Thirty days of resveratrol supplementation does not affect postprandial incretin hormone responses, but suppresses postprandial glucagon in obese subjects

Knop, F. K., Konings, E., Timmers, S., Schrauwen, P., Holst, J. J. & Blaak, E. E., Oct 2013, In: Diabetic Medicine. 30, 10, p. 1214-1218 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

2012

Current evidence for a role of GLP-1 in Roux-en-Y gastric bypass-induced remission of type 2 diabetes

Rhee, N. A., Vilsbøll, T. & Knop, F. K., Apr 2012, In: Diabetes, Obesity and Metabolism. 14, 4, p. 291-298

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials

Vilsbøll, T., Christensen, M., Junker, A. E., Knop, F. K. & Gluud, C. N., 28 Jan 2012, In: B M J (Clinical Research Edition). 344, p. d7771

Research output: Contribution to journal › Journal article › Research › peer-review

566 Citations (Scopus)

Electroretinography in healthy subjects in relation to systemic glucocorticoid intake

Kappelgaard, P., Hansen, K. B., Vilsbøll, T., Knop, F. K. & Larsen, M., Feb 2012, In: Documenta Ophthalmologica. 124, 1, p. 49-57 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity

Knop, F. K., Aaboe, K., Vilsbøll, T., Vølund, A., Holst, J. J., Krarup, T. & Madsbad, S., Jun 2012, In: Diabetes, Obesity and Metabolism. 14, 6, p. 500-510 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

114 Citations (Scopus)

Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects

Hansen, K. B., Vilsbøll, T., Bagger, J. I., Holst, J. J. & Knop, F. K., Apr 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 4, p. 1363-70 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

38 Citations (Scopus)

Increased levels of YKL-40 in patients with chronic pancreatitis and secondary diabetes

Hansen, M., Nielsen, A. R., Vilsbøll, T., Lund, A., Krarup, T., Knop, F. K. & Vestergaard, H., 2012, In: Pancreas.

Research output: Contribution to journal › Journal article › Research › peer-review

Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol

Mandoe, M. J., Hansen, K. B., Knop, F. K., Holst, J. J. & Hansen, H. S., Oct 2012, In: Diabetologia. 55, p. S340-S340

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

The incretin effect in patients with maturity onset diabetes of the young

Ostoft, S. H., Bagger, J. I., Hansen, T., Pedersen, O., Holst, J. J., Knop, F. & Vilsboll, T., 2012, In: Diabetologia. 55, p. S144-S144

Research output: Contribution to journal › Journal article › Research › peer-review

2011

2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans

Hansen, K. B., Rosenkilde, M. M., Knop, F. K., Wellner, N., Diep, T. A., Rehfeld, J. F., Andersen, U. B., Holst, J. J. & Hansen, H. S., Sept 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17

Research output: Contribution to journal › Journal article › Research › peer-review

174 Citations (Scopus)

Comment on: Chen et al. Utilizing the Second-Meal Effect in Type 2 Diabetes: Practical Use of a Soya-Yogurt Snack. Diabetes Care 2010;33:2552-2554

Knop, F. K., 1 Apr 2011, In: Diabetes Care. 34, 4, p. e44

Research output: Contribution to journal › Letter › peer-review

1 Citation (Scopus)

Emerging GLP-1 receptor agonists

Lund, A., Knop, F. K. & Vilsbøll, T., Dec 2011, In: Expert Opinion on Emerging Drugs. 16, 4, p. 607-18 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

First case associating chronic pancreatitis and Ehlers-Danlos syndrome

Hansen, K. B. & Knop, F. K., 2011, In: Pancreas. 40, 1

Research output: Contribution to journal › Journal article › Research › peer-review

Gastric bypass surgery: Improving psoriasis through a GLP-1-dependent mechanism?

Faurschou, A., Zachariae, C., Skov, L., Vilsbøll, T. & Knop, F. K., Dec 2011, In: Medical Hypotheses. 77, 6, p. 1098-1101

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Gastric emptying of orally administered glucose solutions and incretin hormone responses are unaffected by laparoscopic adjustable gastric banding

Usinger, L., Hansen, K. B., Kristiansen, V. B., Larsen, S., Holst, J. J. & Knop, F. K., May 2011, In: Obesity Surgery. 21, 5, p. 625-32 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Glucagon antagonism as a potential therapeutic target in type 2 diabetes

Bagger, J. I., Knop, F. K., Holst, J. J. & Vilsbøll, T., Nov 2011, In: Diabetes, Obesity and Metabolism. 13, 11, p. 965-971 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

87 Citations (Scopus)

Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans

Christensen, M., Vedtofte, L., Holst, J. J., Vilsbøll, T. & Knop, F. K., Dec 2011, In: Diabetes. 60, 12, p. 3103-9 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

181 Citations (Scopus)

Impaired regulation of the incretin effect in patients with type 2 diabetes

Bagger, J. I., Knop, F. K., Lund, A., Vestergaard, H., Holst, J. J. & Vilsbøll, T., Mar 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 3, p. 737-45 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

139 Citations (Scopus)

Increased Postprandial GIP and Glucagon Responses, But Unaltered GLP-1 Response after Intervention with Steroid Hormone, Relative Physical Inactivity, And High-Calorie Diet in Healthy Subjects

Hansen, K. B., Vilsbøll, T., Bagger, J. I., Holst, J. J. & Knop, F. K., Feb 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 2, p. 447-53 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

Inhibition de la sécrétion du glucagon par les antagonistes du GLP-1 et les inhibiteurs de la DPP-4

Hansen, M., Knop, F. K. & Holst, J. J., Apr 2011, In: Medecine des Maladies Metaboliques. 5, 2

Research output: Contribution to journal › Journal article › Research › peer-review

Inhibition of glucagon secretion by GLP-1 agonists and DPP4 inhibitors

Hansen, M., Juul Hare, K., Holst, J. J. & Knop, F. K., Jun 2011, In: Journal of Clinical Metabolism & Diabetes. 2, 2, p. 7-13 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Lixisenatide for type 2 diabetes mellitus

Christensen, M., Knop, F. K., Vilsbøll, T. & Holst, J. J., Apr 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

68 Citations (Scopus)

Filip Krag Knop

Research output

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