Research output per year
Research output per year
Personal profile
Short presentation
The focus of the PhD project is on pharmacokinetic-pharmacodynamic (PK-PD) modelling of morphine's effect on experimental and clinical pain. The aim is to identify factors that can explain the large individual variability in the response to morphine. A better understanding of the large variability is needed for a more individual, and thus more optimal, pain management.
Keywords
- Faculty of Health and Medical Sciences
- PK-PD modelling
- Morphine
- Pain
- Pharmacokinetics
- Pharmacodynamics
- Pharmacometrics
Fingerprint
Dive into the research topics where Eva Sverrisdóttir is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 5 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Midazolam Pharmacokinetics in Obese and Non-obese Children and Adolescents
Gade, C., Sverrisdóttir, E., Dalhoff, K., Sonne, J., Johansen, M. Ø., Christensen, H. R., Burhenne, J., Mikus, G., Holm, J. C., Lund, T. M. & Holst, H., 1 May 2020, In: Clinical Pharmacokinetics.Research output: Contribution to journal › Journal article › Research › peer-review
-
Absorption of Bupivacaine after Administration of a Lozenge as Topical Treatment for Pain from Oral Mucositis
Mogensen, S., Sverrisdóttir, E., Sveinsdóttir, K., Treldal, C., Jensen, K., Jensen, A. B., Kristensen, C. A., Jacobsen, J., Kreilgaard, M., Petersen, J. & Andersen, O., 1 Jan 2017, In: Basic & Clinical Pharmacology & Toxicology. 120, 1, p. 71-78 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
-
Lack of genetic association between OCT1, ABCB1, and UGT2B7 variants and morphine pharmacokinetics
Nielsen, L. M., Sverrisdóttir, E., Stage, T. B., Feddersen, S., Brøsen, K., Christrup, L. L., Drewes, A. M. & Olesen, A. E., 1 Mar 2017, In: European Journal of Pharmaceutical Sciences. 99, p. 337-342 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
-
Pharmacokinetic Metamodel of Morphine and Morphine-6-Glucuronide in Neonates and Adults
Sverrisdóttir, E., Foster, D. J. R., Olesen, A. E., Lund, T. M., Drewes, A. M., Christrup, L. L., Kreilgaard, M. & Upton, R. N., Jun 2016.Research output: Contribution to conference › Poster › Research
105 Downloads (Pure) -
Pharmacokinetic models of morphine and its metabolites in neonates systematic comparisons of models from the literature, and development of a new meta-model
Knøsgaard, K. R., Foster, D. J. R., Kreilgaard, M., Sverrisdóttir, E., Upton, R. N. & van den Anker, J. N., 20 Sept 2016, In: European Journal of Pharmaceutical Sciences.Research output: Contribution to journal › Journal article › Research › peer-review
-
A review of morphine and morphine-6-glucuronide's pharmacokinetic-pharmacodynamic relationships in experimental and clinical pain
Sverrisdóttir, E., Lund, T. M., Olesen, A. E., Drewes, A. M., Christrup, L. L. & Kreilgaard, M., 10 Jul 2015, In: European Journal of Pharmaceutical Sciences. 74, p. 45–62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
-
Modelling concentration-analgesia relationships for morphine to evaluate experimental pain models
Sverrisdóttir, E., Foster, D. J. R., Upton, R. N., Olesen, A. E., Lund, T. M., Gabel-Jensen, C., Drewes, A. M., Christrup, L. L. & Kreilgaard, M., 23 Jan 2015, In: European Journal of Pharmaceutical Sciences. 66, p. 50-58 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
-
Modelling drug-drug interactions between morphine and methylnaltrexone
Sverrisdóttir, E., Kreilgaard, M., Brokjær, A., Miltersen, K. K., Olesen, A. E., Christrup, L. L. & Drewes, A., 2015.Research output: Contribution to conference › Poster › Research
Activities
- 1 Lecture and oral contribution
-
Population PKPD model of morphine
Sverrisdóttir, E. (Lecturer)
16 Apr 2013Activity: Talk or presentation types › Lecture and oral contribution