Research output per year
Research output per year
Personal profile
Short presentation
I am generally of an inquisitive nature. I enjoy the process from idea to result and I work methodically and systematically to achieve this. It is important to me to be part of a dynamic and innovative collaboration with my colleagues as well as to be able to work independently with my own ideas and see my work evolve. I am a sympathetic nerd with great enthusiasm and a wish to evolve and improve my skills.
Current research
Since February 2017, I have been a postdoc in the Nielsen group at CPR. The group focuses on developing novel proteomics methods & technologies for detailing cellular outcomes in a systems-level approach, with the aim to improve current understanding of cellular phenotypes and diseases. To this end, we employ cutting-edge mass spectrometry (MS)-based technologies and the Nielsen group has developed several novel proteomics methodologies for identification and quantification of various post-translational modifications (PTMs).
My project revolves around ubiquitin and ubiquitylation. Ubiquitin is a small protein that, when attached to a target protein, alters the function or fate of this target. Because ubiquitin can be attached both as single units and as chains of different topologies, the resulting signal is highly complex. Indeed, ubiquitin signalling is involved in most cellular functions and is aberrant in various diseases including neurodegeneration and cancer. The aim of this project is to develop a novel method that uniquely will decipher the incredible complexity of ubiquitin signalling.
Primary fields of research
Proteomics, Molecular and Cellular Biology
Fields of interest
Genome stability
Cell cycle regulation
DNA repair
DNA stress and damage responses
Checkpoint signalling
Teaching
Molecular Genetics (Laboratory instructor)
Almen Molekylær Biologi (Laboratory instructor)
Possible conflicts of interest
None
Knowledge of languages
Danish (first language)
English (fluent)
CV
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Work experience | |||
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2017- |
Postdoc Developing a mass spectrometry-based technology for investigating ubiquitination in Xenopus Laevis |
University of Copenhagen NNF CPR Prof. Michael Lund Nielsen | |
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2016-2017 |
Postdoc Completion and publication of PhD thesis manuscript |
University of Copenhagen, Department of Biology Prof. Michael Lisby | |
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2012-2013 |
Research assistant Metagenomics |
University of Copenhagen, Department of Biology Prof. Karsten Kristiansen | |
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2009- 2012 |
Student assistant Administrative and laboratory ad hoc, database programming and administration. |
University of Copenhagen, Department of Biology Prof. Karsten Kristiansen | |
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Education | |||
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2016 |
PhD Molecular Biomedicine, Thesis title: Regulation of replication recovery and genome integrity: Cdc48-mediated turnover of Mrc1 and Cmr1 in INQ Model organism: Saccharomyces cerevisiae |
University of Copenhagen, Department of Biology Prof. Michael Lisby | |
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2012 |
M.Sc. Molecular Biomedicine, Thesis title: Functional characterization of the monomethyltransferase SET8 in genomic integrity Model organism: Mammalian cell culture |
University of Copenhagen, BRIC Assoc. Prof. Claus Sørensen | |
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2010 |
B.Sc. Molecular Biomedicine, Thesis title: Adenosine triphosphate release from pancreatic acinar cells with noxious stimuli Model organism: Mice (isolated primary pancreatic acini) |
University of Copenhagen, Department of Biology Prof. Ivana Novak | |
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Volunteer activity | |||
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2018 |
Head of the local organizing committee for the 2018 ENABLE symposium |
University of Copenhagen NNF CPR | |
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2014 |
Head of the 2014 BIO PhD Day organizing committee |
University of Copenhagen, Department of Biology | |
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2016 |
Consultant for the new yeast exhibition |
Experimentarium, Copenhagen | |
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Work and educational travelling activity | |||
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2018 |
66th ASMS Conference on Mass Spectrometry and Allied Topics Poster presentation |
San Diego, California, USA | |
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2015 |
3 month visit during PhD Biochemical experiments |
Max Planck institute for biochemistry and neurobiology Boris Pfander | |
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2015 |
27th international conference on yeast genetics and molecular biology Poster presentation |
Levico Terme, Trentino, Italy | |
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2013 |
EMBO: The DNA Damage Response in Cell Physiology and Disease Poster presentation |
Cape Sunio, Greece | |
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2013 |
EMBO: Ubiquitin and Ubiquitin-like proteins: From Structure to Function Poster presentation |
Riva del Garda, Italy | |
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2010 |
Laboratory work during employment as student assistant Metagenomics |
University of Gothenburg, Wallenberg Laboratory | |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- Faculty of Health and Medical Sciences
- Proteomics
- mass spectrometry
- Xenopus Laevis egg extracts
- Ubiquitin
- DNA damage/replication
Fingerprint
Dive into the research topics where Camilla S.Colding-Christensen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 12 Similar Profiles
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Regulation of Replication Recovery and Genome Integrity: Cdc48-Mediated Turnover of Mrc1 and Cmr1 in INQ
Colding, C. S., 2016, Department of Biology, Faculty of Science, University of Copenhagen. 235 p.Research output: Book/Report › Ph.D. thesis
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A catalog of the mouse gut metagenome
Xiao, L., Feng, Q., Liang, S., Sonne, S. B., Xia, Z., Qiu, X., Li, X., Long, H., Zhang, J., Zhang, D., Liu, C., Fang, Z., Chou, J., Glanville, J., Hao, Q., Kotowska, D. E., Colding, C. S., Licht, T. R., Wu, D. & Yu, J. & 17 others, , 1 Oct 2015, In: Nature Biotechnology. 33, 10, p. 1103-1108 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control
Gallina, I., Colding, C. S., Henriksen, P., Beli, P., Nakamura, K., Offman, J., Barfred, D. P., Pinela da Silva, S. C., Hoffmann, E., Groth, A., Choudhary, C. & Lisby, M., Mar 2015, In: Nature Communications. 6, 16 p., 6533.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamics and stabilization of the human gut microbiome during the first year of life
Bäckhed, G. F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., Li, Y., Xia, Y., Xie, H., Zhong, H., Khan, M. T., Zhang, J., Li, J., Xiao, L., Al-Aama, J., Zhang, D., Lee, Y. S., Kotowska, D. E., Colding, C. S. & Tremaroli, V. & 7 others, , 13 May 2015, In: Cell Host & Microbe. 17, 5, p. 690-703 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Activities
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EMBO: Ubiquitin and related modifiers
Colding-Christensen, C. S. (Participant)
6 Sept 2014 → 13 Sept 2014Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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2014 PhD Day organizing committee (External organisation)
Colding-Christensen, C. S. (Chair)
1 Jan 2014 → 30 Nov 2014Activity: Membership types › Membership in committee, council, board
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EMBO: The DNA damage response in cell physiology and disease
Colding-Christensen, C. S. (Participant)
7 Oct 2013 → 11 Oct 2013Activity: Participating in or organising an event types › Organisation of and participation in conference
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EMBO: Ubiquitin and ubiquitin-like proteins:From structure to function
Colding-Christensen, C. S. (Participant)
1 Oct 2013 → 5 Oct 2013Activity: Participating in or organising an event types › Organisation of and participation in conference
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Chromatin, Replication and Chromosomal Stability 2013
Colding-Christensen, C. S. (Participant)
17 Jun 2013 → 19 Jun 2013Activity: Participating in or organising an event types › Organisation of and participation in conference