Research output per year
Research output per year
Search results
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2019
Mesodermal induction of pancreatic fate commitment
Seymour, P. A. & Serup, P., Aug 2019, In: Seminars in Cell and Developmental Biology. 92, p. 77-88Research output: Contribution to journal › Review › peer-review
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2018
Dll1 and Jag1 are differentially required to specify proximal and distal pancreatic duct compartments.
Seymour, P. A., Collin, C. A., Jorgensen, M. C., Imayoshi, I., Kageyama, R. & Serup, P., 2018, (E-pub ahead of print) In: bioRxiv, Developmental Biology. p. 1-36 36 p.Research output: Contribution to journal › Journal article › Research
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Inhibition of Cdk5 Promotes β-Cell Differentiation From Ductal Progenitors
Liu, K.-C., Leuckx, G., Sakano, D., Seymour, P. A., Mattsson, C. L., Rautio, L., Staels, W., Verdonck, Y., Serup, P., Kume, S., Heimberg, H. & Andersson, O., 1 Jan 2018, In: Diabetes. 67, 1, p. 58-70 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanosignalling via integrins directs fate decisions of pancreatic progenitors
Mamidi, A., Prawiro, C., Seymour, P. A., de Lichtenberg, K. H., Jackson, A., Serup, P. & Semb, H., 6 Dec 2018, In: Nature. 564, 7734, p. 114-118 5 p.Research output: Contribution to journal › Letter › peer-review
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Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice
Jørgensen, M. C., de Lichtenberg, K. H., Collin, C. A., Klinck, R., Ekberg, J. H., Engelstoft, M. S., Lickert, H. & Serup, P., Sept 2018, In: Development (Cambridge, England). 145, 17, p. 1-11 11 p., dev163568.Research output: Contribution to journal › Journal article › Research › peer-review
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Notch controls multiple pancreatic cell fate regulators through direct hes1-mediated repression.
de Lichtenberg, K. H., Seymour, P. A., Joergensen, M. C., Kim, Y.-H., Grapin-Botton, A., Magnuson, M. A., Nakic, N., Ferrer, J. & Serup, P., 2018, (E-pub ahead of print) In: bioRxiv, Developmental Biology. p. 1-30 30 p.Research output: Contribution to journal › Journal article › Research
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2017
Anteroposterior polarity and elongation in the absence of extraembryonic tissues and of spatially localised signalling in gastruloids: Mammalian embryonic organoids
Turner, D. A., Girgin, M., Alonso-Crisostomo, L., Trivedi, V., Baillie-Johnson, P., Glodowski, C. R., Hayward, P. C., Collignon, J., Gustavsen, C., Serup, P., Steventon, B., Lutolf, M. P. & Arias, A. M., Nov 2017, In: Development (Cambridge). 144, 21, p. 3894-3906 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Parsing the Pancreas
Grapin-Botton, A. & Serup, P., 2 Mar 2017, In: New England Journal of Medicine. 376, 9, p. 886-888 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Properties of embryoid bodies
Brickman, J. M. & Serup, P., 1 Mar 2017, In: Developmental Biology. 6, 2, 11 p., e259.Research output: Contribution to journal › Review › peer-review
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2016
Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo
Horn, S., Kirkegaard, J. S., Hoelper, S., Seymour, P. A., Rescan, C., Nielsen, J. H., Madsen, O. D., Jensen, J. N., Kruger, M., Gronborg, M. & Ahnfelt-Rønne, J., Jan 2016, In: Molecular endocrinology (Baltimore, Md.). 30, 1, p. 133-143 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2015
A conserved role for Notch in priming the cellular response to Shh through ciliary localisation of the key Shh transducer, Smoothened
Stasiulewicz, M., Gray, S., Mastromina, I., Silva, J. C., Bjorklund, M., Seymour, P. A., Booth, D., Thompson, C., Green, R., Hall, E. A., Serup, P. & Dale, J. K., 1 Jul 2015, In: Development. 142, p. 2291-2303 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells
Shih, H. P., Seymour, P. A., Patel, N. A., Xie, R., Wang, A., Liu, P. P., Yeo, G. W., Magnuson, M. A. & Sander, M., 13 Oct 2015, In: Cell Reports. 13, 2, p. 326-36 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pairing-up SOX to kick-start beta cell genesis
Grapin-Botton, A., Seymour, P. A. & Gradwohl, G., 1 May 2015, In: Diabetologia. 58, 5, p. 859-861 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2014
Prdm5 suppresses Apc(Min)-driven intestinal adenomas and regulates monoacylglycerol lipase expression
Galli, G. G., Multhaupt, H. A., Carrara, M., Honnens de Lichtenberg, K., Christensen, I. B. J., Linnemann, D., Santoni-Rugiu, E., Calogero, R. A. & Lund, A. H., 19 Jun 2014, In: Oncogene.Research output: Contribution to journal › Journal article › Research › peer-review
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Sox9: a master regulator of the pancreatic program
Seymour, P. A., 2014, In: The Review of Diabetic Studies. 11, 1, p. 51-83 33 p.Research output: Contribution to journal › Review › peer-review
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The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube
Hanotel, J., Bessodes, N., Thélie, A., Hedderich, M., Parain, K., Driessche, B. V., Brandão, K. D. O., Kricha, S., Jorgensen, M. C., Grapin-Botton, A., Serup, P., Lint, C. V., Perron, M., Pieler, T., Henningfeld, K. A. & Bellefroid, E. J., 15 Feb 2014, In: Developmental Biology. 386, 2, p. 340–357 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2013
Bulking up on beta cells
Seymour, P. A. & Serup, P., 22 Aug 2013, In: Briefings from the New England Journal of Medicine (Spanish Edition). 369, 8, p. 777-9 3 p.Research output: Contribution to journal › Review › peer-review
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2012
A Functional Assay for Putative Mouse and Human Definitive Endoderm using Chick Whole-Embryo Cultures
Johannesson, M., Semb, T. H., Serup, P. & Hansson, M., 21 Sept 2012, In: Stem Cell Research & Therapy. 2, 128, p. 2-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mind bomb 1 is required for pancreatic ß-cell formation
Horn, S., Kobberup, S., Jørgensen, M. C., Kalisz, M., Klein, T., Kageyama, R., Gegg, M., Lickert, H., Lindner, J., Magnuson, M. A., Kong, Y.-Y., Serup, P., Ahnfelt-Rønne, J. & Jensen, J. N., 8 May 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 19, p. 7356-61 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice
Serup, P., Gustavsen, C., Klein, T., Potter, L. A., Lin, R., Mullapudi, N., Wandzioch, E., Hines, A., Davis, A., Bruun, C., Engberg, N., Petersen, D. R., Peterslund, J. M. L., Macdonald, R. J., Grapin-Botton, A., Magnuson, M. A. & Zaret, K. S., 1 Nov 2012, In: Disease Models and Mechanisms. 5, 6, p. 956-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Signaling pathways regulating murine pancreatic development
Serup, P., 1 Aug 2012, In: Seminars in Cell and Developmental Biology. 23, 6, p. 663-72 10 p.Research output: Contribution to journal › Review › peer-review
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1996
Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1
Serup, P., Jensen, J., Andersen, F. G., Jørgensen, M. C., Blume, N., Holst, J. J. & Madsen, O. D., 20 Aug 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 17, p. 9015-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
129 Citations (Scopus) -
1992
Immature transformed rat islet beta-cells differentially express C-peptides derived from the genes coding for insulin I and II as well as a transfected human insulin gene
Blume, N., Petersen, J. S., Andersen, L. C., Kofod, H., Dyrberg, T., Michelsen, B. K., Serup, P. & Madsen, O. D., Feb 1992, In: Molecular Endocrinology. 6, 2, p. 299-307 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus)