Computational and RNA Biology

2018

Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter-encoded enhancer activities

Rennie, S., Dalby, M., Lloret-Llinares, M., Bakoulis, S., Dalager Vaagensø, C., Jensen, T. H. & Andersson, R., 20 Jun 2018, In: Nucleic Acids Research. 46, 11, p. 5455-5469 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

39 Downloads (Pure)

Transfer RNA instability as a stress response in Escherichia coli: rapid dynamics of the tRNA pool as a function of demand

Sørensen, M. A., Fehler, A. O. & Svenningsen, S. L., 4 May 2018, In: RNA Biology. 15, 4/5, p. 586-593 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

62 Downloads (Pure)

2017

A Generative Angular Model of Protein Structure Evolution

Golden, M., Garcia-Portugues, E., Sørensen, M., Mardia, K. V., Hamelryck, T. & Hein, J., 1 Aug 2017, In: Molecular Biology and Evolution. 34, 8, p. 2085-2100

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

69 Downloads (Pure)

Analysing human genomes at different scales

Liu, S., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

Research output: Book/Report › Ph.D. thesis

Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion

Danish Pan Genome Consortium, Sørensen, L. M., Petersen, B., Sibbesen, J. A., Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Hansen, T., Krogh, A., Sørensen, T. I. A., Pedersen, O. B., Rasmussen, S., Kristiansen, K. & Brunak, S., Aug 2017, In: PLOS Genetics. 13, 8, p. e1006834

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers

Sikora, M., Seguin-Orlando, A., Sousa, V. C., Albrechtsen, A., Korneliussen, T. S., Ko, A., Rasmussen, S., Dupanloup, I., Nigst, P. R., Bosch, M. D., Renaud, G., Allentoft, M. E., Margaryan, A., Vasilyev, S. V., Veselovskaya, E. V., Borutskaya, S. B., Deviese, T., Comeskey, D., Higham, T., Manica, A., & 7 othersFoley, R., Meltzer, D. J., Nielsen, R., Excoffler, L., Lahr, M. M., Orlando, L. A. A. & Willerslev, E., 3 Nov 2017, In: Science. 358, 6363, p. 659-662 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

93 Citations (Scopus)

43 Downloads (Pure)

Ancient genomic changes associated with domestication of the horse

Sanz, P. L., Gamba, C., Gaunitz, C., Der Sarkissian, C., Pruvost, M., Albrechtsen, A., Fages, A. A., Khan, N., Schubert, M., Jagannathan, V., Serres-Armero, A., Kuderna, L. F. K., Povolotskaya, I. S., Seguin-Orlando, A., Lepetz, S., Neuditschko, M., Thèves, C., Alquraishi, S., Alfarhan, A. H., AL-Rasheid, K., & 13 othersRieder, S., Samashev, Z., Francfort, H-P., Benecke, N., Hofreiter, M., Ludwig, A., Keyser, C., Marques-Bonet, T., Ludes, B., Crubézy, E., Leeb, T., Willerslev, E. & Orlando, L. A. A., 28 Apr 2017, In: Science. 356, 6336, p. 442-445 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

91 Citations (Scopus)

An integrated expression atlas of miRNAs and their promoters in human and mouse

de Rie, D., Abugessaisa, I., Alam, T., Arner, E., Arner, P., Ashoor, H., Åström, G., Babina, M., Bertin, N., Burroughs, A. M., Carlisle, A. J., Daub, C. O., Detmar, M., Deviatiiarov, R., Fort, A., Gebhard, C., Goldowitz, D., Guhl, S., Ha, T. J., Harshbarger, J., & 31 othersHasegawa, A., Hashimoto, K., Herlyn, M., Heutink, P., Hitchens, K. J., Hon, C. C., Huang, E., Ishizu, Y., Kai, C., Kasukawa, T., Klinken, P., Lassmann, T., Lecellier, C-H., Lee, W., Lizio, M., Makeev, V., Mathelier, A., Medvedeva, Y. A., Mejhert, N., Mungall, C. J., Noma, S., Ohshima, M., Okada-Hatakeyama, M., Persson, H., Rizzu, P., Roudnicky, F., Sætrom, P., Sato, H., Vitting-Seerup, K., Sandelin, A. G. & FANTOM Consortium, 1 Sept 2017, In: Nature Biotechnology. 35, 9, p. 872-878 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

183 Citations (Scopus)

An introduction to deep learning on biological sequence data: examples and solutions

Jurtz, V. I., Johansen, A. R., Nielsen, M., Almagro Armenteros, J. J., Nielsen, H., Sønderby, C. K., Winther, O. & Sønderby, S. K., 15 Nov 2017, In: Bioinformatics. 33, 22, p. 3685-3690 6 p.

Research output: Contribution to journal › Review › peer-review

49 Citations (Scopus)

Applying targeted next generation sequencing to dried blood spot specimens from suspicious cases identified by tandem mass spectrometry-based newborn screening

Qian, J., Wang, X., Liu, J., Zhong, J., Le, Y., Tellier, L. C. A. M., Liu, C., Jiang, P., Gao, R. & Wang, Y., 28 Aug 2017, In: Journal of Pediatric Endocrinology and Metabolism. 30, 9, p. 979-988 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Archaic adaptive introgression in TBX15/WARS2

Racimo, F., Gokhman, D., Fumagalli, M., Ko, A., Hansen, T., Moltke, I., Albrechtsen, A., Carmel, L., Huerta-Sánchez, E. & Nielsen, R., 2017, In: Molecular Biology and Evolution. 34, 3, p. 509-524 16 p., msw283.

Research output: Contribution to journal › Journal article › Research › peer-review

50 Citations (Scopus)

83 Downloads (Pure)

Assembly and analysis of 100 full MHC haplotypes from the Danish population

Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., Sørensen, L. M., Petersen, B., Sibbesen, J. A., Liu, S., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R., & 39 othersYe, W., Rao, J., Guo, X., Sun, J., Cao, H., Ye, C., Beusekom, J. V., Espeseth, T., Flindt, E., Halager, A. E., Hellard, S. L., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, D., Yadav, R., Li, N., Xu, X., Hansen, T., Bolund, L., Krogh, A., Sørensen, T. I. A., Pedersen, O. B., Gupta, R., Rasmussen, S., Børglum, A. D., Wang, J., Eiberg, H. R. L., Kristiansen, K., Brunak, S. & Schierup, M. H., Sept 2017, In: Genome Research. 27, 9, p. 1597-1607 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

150 Downloads (Pure)

Chirality in microbial biofilms is mediated by close interactions between the cell surface and the substratum

Jauffred, L., Vejborg, R. M., Korolev, K. S., Brown, S. & Oddershede, L. B., 1 Jul 2017, In: I S M E Journal. 11, 7, p. 1688-1701

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

70 Downloads (Pure)

Climate change and human colonization triggered habitat loss and fragmentation in Madagascar

Salmona, J., Heller, R., Quéméré, E. & Chikhi, L., Oct 2017, In: Molecular Ecology. 26, 19, p. 5203-5222 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

DeepLoc: prediction of protein subcellular localization using deep learning

Almagro Armenteros, J. J., Sønderby, C. K., Sønderby, S. K., Nielsen, H. & Winther, O., 1 Nov 2017, In: Bioinformatics. 33, 21, p. 3387-3395 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

281 Citations (Scopus)

Deep Recurrent Conditional Random Field Network for Protein Secondary Prediction

Johansen, A. R., Sønderby, C. K., Sønderby, S. K. & Winther, O., 20 Aug 2017, ACM-BCB '17: Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics. p. 73-78 6 p.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

12 Citations (Scopus)

64 Downloads (Pure)

Demographic inferences from large-scale NGS data

Pedersen, C-E. T., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

Research output: Book/Report › Ph.D. thesis

De novo pathway-based biomarker identification

Alcaraz, N., List, M., Batra, R., Vandin, F., Ditzel, H. J. & Baumbach, J., 19 Sept 2017, In: Nucleic Acids Research. 45, 16, 11 p., e151.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

61 Downloads (Pure)

Discrete structural dynamics of pseudo-palindromic motifs control DNA binding of bacterial toxin-antitoxin complexes

Brodersen, D. E., Bendtsen, K. L., Xu, K., Luckmann, M., Winther, K. S., Shah, S. A. & Pedersen, C. N. S., 2017, In: F A S E B Journal. 31, S1, 1 p., 777.2.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Diversity of nature's assembly lines - recent discoveries in non-ribosomal peptide synthesis

Payne, J. A. E., Schoppet, M., Hansen, M. H. & Cryle, M. J., 2017, In: Molecular BioSystems. 13, 1, p. 9-22 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

Eight millennia of matrilineal genetic continuity in the South Caucasus

Margaryan, A., Derenko, M., Hovhannisyan, H., Malyarchuk, B., Heller, R., Khachatryan, Z., Avetisyan, P., Badalyan, R., Bobokhyan, A., Melikyan, V., Sargsyan, G., Piliposyan, A., Simonyan, H., Mkrtchyan, R., Denisova, G., Yepiskoposyan, L., Willerslev, E. & Allentoft, M. E., 10 Jul 2017, In: Current Biology. 27, 13, p. 2023-2028 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Extinctions, genetic erosion and conservation options for the black rhinoceros (Diceros bicornis)

Moodley, Y., Russo, I-R. M., Dalton, D. L., Kotzé, A., Muya, S., Haubensak, P., Bálint, B., Munimanda, G. K., Deimel, C., Setzer, A., Dicks, K., Herzig-Straschil, B., Kalthoff, D. C., Siegismund, H. R., Robovský, J., O'Donoghue, P. & Bruford, M. W., 8 Feb 2017, In: Scientific Reports. 7, 16 p., 41417.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

62 Downloads (Pure)

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, J. V., Rapin, N. P. J-P., Porse, B. T., Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., 1 Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

206 Citations (Scopus)

fastNGSadmix: admixture proportions and principal component analysis of a single NGS sample

Jørsboe, E., Hanghøj, K. E. & Albrechtsen, A., 1 Oct 2017, In: Bioinformatics. 33, 19, p. 3148-3150 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Founder effect of the RET^C611Y mutation in multiple endocrine neoplasia 2A in Denmark: a nationwide Study

Sloth Mathiesen, J., Kroustrup, J. P., Vestergaard, P., Krag, K. S., Poulsen, P. L., Rasmussen, Å. K., Feldt-Rasmussen, U., Gaustadnes, M., Ørntoft, T. F., Rossing, M., Nielsen, F. C., Albrechtsen, A., Brixen, K., Godballe, C. & Frederiksen, A. L., Dec 2017, In: Thyroid. 27, 12, p. 1505-1510 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Genetic screening of the FLCN gene identify six novel variants and a Danish founder mutation

Rossing, M., Albrechtsen, A., Skytte, A-B., Jensen, U. B., Ousager, L. B., Gerdes, A-M. A., Nielsen, F. C. & Hansen, T. V. O., 1 Feb 2017, In: Journal of Human Genetics. 62, p. 151-157 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types

Ecker, S., Chen, L., Pancaldi, V., Bagger, F. O., Fernández, J. M., Carrillo de Santa Pau, E., Juan, D., Mann, A. L., Watt, S., Casale, F. P., Sidiropoulos, N., Rapin, N. P. J-P., Merkel, A., Stunnenberg, H. G., Stegle, O., Frontini, M., Downes, K., Pastinen, T., Kuijpers, T. W., Rico, D., & 50 othersValencia, A., Beck, S., Soranzo, N., Paul, D. S., Albers, C. A., Amstislavskiy, V., Ashford, S., Bomba, L., Bujold, D., Burden, F., Busche, S., Caron, M., Chen, S-H., Cheung, W. A., Clarke, L., Colgiu, I., Datta, A., Delaneau, O., Elding, H., Farrow, S., Garrido-Martín, D., Ge, B., Guigo, R., Iotchkova, V., Kundu, K., Kwan, T., Lambourne, J. J., Lowy, E., Mead, D., Pourfarzad, F., Redensek, A., Rehnstrom, K., Rendon, A., Richardson, D. M., Risch, T., Rowlston, S., Shao, X., Simon, M. M., Sultan, M., Walter, K., Wilder, S. P., Yan, Y., Antonarakis, S. E., Bourque, G., Dermitzakis, E. T., Flicek, P., Lehrach, H., Martens, J. H. A., Yaspo, M-L. & Ouwehand, W. H., 26 Jan 2017, In: Genome Biology. 18, 1, 17 p., 18.

Research output: Contribution to journal › Journal article › Research › peer-review

48 Citations (Scopus)

151 Downloads (Pure)

Heat-shock protein 40 is the key farnesylation target in meristem size control, abscisic acid signaling, and drought resistance

Barghetti, A., Sjögren, L. L. E., Floris, M. H. J., Botterweg Paredes, E., Wenkel, S. & Brodersen, P., 30 Nov 2017, In: Genes & Development. 31, 22, p. 2282-2295 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

104 Downloads (Pure)

Highly accessible AU-rich regions in 3' untranslated regions are hotspots for binding of regulatory factors

Plass, M., Rasmussen, S. H. & Krogh, A., 14 Apr 2017, In: PLoS Computational Biology. 13, 4, 26 p., e1005460.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

253 Downloads (Pure)

Identification of gene transcription start sites and enhancers responding to pulmonary carbon nanotube exposure in Vivo

Lange, J. B., Saber, A. T., Lilje, B., Boyd, M., Jørgensen, M., Chen, Y., Vitezic, M., Jacobsen, N. R., Poulsen, S. S., Berthing, T., Bressendorff, S., Vitting-Seerup, K., Andersson, R., Hougaard, K. S., Yauk, C. L., Halappanavar, S., Wallin, E. H. R., Vogel, U. & Sandelin, A. G., 25 Apr 2017, In: A C S Nano. 11, 4, p. 3597-3613 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Investigating membrane-bound Argonaute functions in Arabidopsis

Barghetti, A., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

Research output: Book/Report › Ph.D. thesis

Marine genomics: news and views

Oliveira Ribeiro, Â. M., Foote, A. D., Kupczok, A., Frazão, B., Limborg, M. T., Piñeiro, R., Abalde, S., Rocha, S. & Rodrigues da Fonseca, R. A., 1 Feb 2017, In: Marine Genomics. 31, p. 1-8 8 p.

Research output: Contribution to journal › Review › peer-review

9 Citations (Scopus)

Molecular clocks indicate turnover and diversification of modern coleoid cephalopods during the Mesozoic Marine Revolution

Tanner, A. R., Fuchs, D., Winkelmann, I. E. H., Gilbert, T., Pankey, M. S., Oliveira Ribeiro, Â. M., Kocot, K. M., Halanych, K. M., Oakley, T. H., Rodrigues da Fonseca, R. A., Pisani, D. & Vinther, J., 15 Mar 2017, In: Proceedings of the Royal Society B: Biological Sciences. 284, 1850, 7 p., 20162818.

Research output: Contribution to journal › Journal article › Research › peer-review

47 Citations (Scopus)

79 Downloads (Pure)

Novel targeted therapies for inflammatory bowel disease

Coskun, M., Vermeire, S. & Nielsen, O. H., 1 Feb 2017, In: Trends in Pharmacological Sciences. 38, 2, p. 127-142 16 p.

Research output: Contribution to journal › Review › peer-review

77 Citations (Scopus)

Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression

Pinto, R., Hansen, L., Hintze, J. B. H., Almeida, R., Larsen, S., Coskun, M., Davidsen, J., Mitchelmore, C., David, L., Troelsen, J. T. & Bennett, E. P., 1 Jul 2017, In: Nucleic Acids Research. 45, 13, 15 p., e123.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

99 Downloads (Pure)

Regulation of laminin γ2 expression by CDX2 in colonic epithelial cells is impaired during active inflammation

Coskun, M., Soendergaard, C., Joergensen, S., Dahlgaard, K., Riis, L. B., Nielsen, O. H., Sandelin, A. G. & Troelsen, J. T., 1 Feb 2017, In: Journal of Cellular Biochemistry. 118, 2, p. 298-307 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels

Chen, Y., Salem, M., Boyd, M., Bornholdt, J., Li, Y., Coskun, M., Seidelin, J. B., Sandelin, A. & Nielsen, O. H., 2017, In: npj Genomic Medicine. 2, 11 p., 3.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

21 Downloads (Pure)

RNase H sequence preferences influence antisense oligonucleotide efficiency

Kiełpiński, Ł. J., Hagedorn, P. H., Lindow, M. & Vinther, J., 15 Dec 2017, In: Nucleic Acids Research. 45, 22, p. 12932-12944 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

44 Downloads (Pure)

Sequence Analysis

Sønderby, S. K., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

Research output: Book/Report › Ph.D. thesis

Sequencing and de novo assembly of 150 genomes from Denmark as a population reference

Sørensen, L. M., Jensen, J. M., Petersen, B., Sibbesen, J. A., Liu, S., Villesen, P., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R., Ye, W., Rao, J., Guo, X., & 39 othersSun, J., Cao, H., Ye, C., van Beusekom, J., Espeseth, T., Flindt, E., Friborg, R. M., Halager, A. E., Le Hellard, S., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Mailund, T., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, D., Yadav, R., Li, N., Xu, X., Hansen, T., Krogh, A., Bolund, L., Sørensen, T. I. A., Pedersen, O. B., Gupta, R., Rasmussen, S., Besenbacher, S., Børglum, A. D., Wang, J., Eiberg, H. R. L., Kristiansen, K., Brunak, S. & Schierup, M. H., 3 Aug 2017, In: Nature. 548, 7665, p. 87-91 5 p.

Research output: Contribution to journal › Letter › peer-review

52 Citations (Scopus)

291 Downloads (Pure)

Sphingosine-1-phosphate signaling in inflammatory bowel disease

Nielsen, O. H., Li, Y., Lindbom, B. J. & Coskun, M., 1 Apr 2017, In: Trends in Molecular Medicine. 23, 4, p. 362-374 13 p.

Research output: Contribution to journal › Review › peer-review

32 Citations (Scopus)

Structures and Interactions of Proteins in the Brain: The Interaction Between LRP1 and Aß & Structure and Self-Assembly of Arc

Nielsen, L. D., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

Research output: Book/Report › Ph.D. thesis

Sugar metabolism of the first thermophilic Planctomycete Thermogutta terrifontis: comparative genomic and transcriptomic approaches

Elcheninov, A. G., Menzel, P., Gudbergsdottir, S. R., Slesarev, A. I., Kadnikov, V. V., Krogh, A., Bonch-Osmolovskaya, E. A., Peng, X. & Kublanov, I. V., 2 Nov 2017, In: Frontiers in Microbiology. 8, 11 p., 2140.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

71 Downloads (Pure)

Targeted next-generation sequencing analysis identifies novel mutations in families with severe familial exudative vitreoretinopathy

Huang, X-Y., Zhuang, H., Wu, J-H., Li, J-K., Hu, F-Y., Zheng, Y., Tellier, L. C. A. M., Zhang, S-H., Gao, F-J., Zhang, J-G. & Xu, G-Z., 23 Aug 2017, In: Molecular Vision. 23, p. 605-613 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

10 Downloads (Pure)

The Bipolar Illness Onset study: research protocol for the BIO cohort study

Kessing, L. V., Munkholm, K., Faurholt-Jepsen, M., Miskowiak, K. W., Nielsen, L. B., Frikke-Schmidt, R., Ekstrøm, C. T., Winther, O., Pedersen, B. K., Poulsen, H. E., McIntyre, R. S., Kapczinski, F., Gattaz, W. F., Bardram, J., Frost, M., Mayora, O., Knudsen, G. M., Phillips, M. & Vinberg, M., 2017, In: BMJ Open. 7, 6, 12 p., e015462.

Research output: Contribution to journal › Journal article › Research › peer-review

55 Citations (Scopus)

165 Downloads (Pure)

The effect of an extreme and prolonged population bottleneck on patterns of deleterious variation: insights from the Greenlandic Inuit

Pedersen, C-E. T., Lohmueller, K. E., Grarup, N., Bjerregaard, P., Hansen, T., Siegismund, H. R., Moltke, I. & Albrechtsen, A., Feb 2017, In: Genetics. 205, 2, p. 787-801 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

The landscape of isoform switches in human cancers

Vitting-Seerup, K. & Sandelin, A. G., 1 Sept 2017, In: Molecular Cancer Research. 15, 9, p. 1206-1220 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

50 Citations (Scopus)

The whole-genome landscape of medulloblastoma subtypes

Northcott, P. A., Buchhalter, I., Morrissy, A. S., Hovestadt, V., Weischenfeldt, J., Ehrenberger, T., Gröbner, S., Segura-Wang, M., Zichner, T., Rudneva, V. A., Warnatz, H. J., Sidiropoulos, N., Phillips, A. H., Schumacher, S., Kleinheinz, K., Waszak, S. M., Erkek, S., Jones, D. T. W., Worst, B. C., Kool, M., & 67 othersZapatka, M., Jäger, N., Chavez, L., Hutter, B., Bieg, M., Paramasivam, N., Heinold, M., Gu, Z., Ishaque, N., Jäger-Schmidt, C., Imbusch, C. D., Jugold, A., Hübschmann, D., Risch, T., Amstislavskiy, V., Gonzalez, F. G. R., Weber, U. D., Wolf, S., Robinson, G. W., Zhou, X., Wu, G., Finkelstein, D., Liu, Y., Cavalli, F. M. G., Luu, B., Ramaswamy, V., Wu, X., Koster, J., Ryzhova, M., Cho, Y. J., Pomeroy, S. L., Herold-Mende, C., Schuhmann, M., Ebinger, M., Liau, L. M., Mora, J., McLendon, R. E., Jabado, N., Kumabe, T., Chuah, E., Ma, Y., Moore, R. A., Mungall, A. J., Mungall, K. L., Thiessen, N., Tse, K., Wong, T., Jones, S. J. M., Witt, O., Milde, T., Von Deimling, A., Capper, D., Korshunov, A., Yaspo, M. L., Kriwacki, R., Gajjar, A., Zhang, J., Beroukhim, R., Fraenkel, E., Korbel, J. O., Brors, B., Schlesner, M., Eils, R., Marra, M. A., Pfister, S. M., Taylor, M. D. & Lichter, P., 19 Jul 2017, In: Nature. 547, 7663, p. 311-317 7 p.

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342 Citations (Scopus)

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Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding

Bendtsen, K. L., Xu, K., Luckmann, M., Winther, K. S., Shah, S. A., Pedersen, C. N. S. & Brodersen, D. E., 17 Mar 2017, In: Nucleic Acids Research. 45, 5, p. 2875-2886 12 p.

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12 Citations (Scopus)

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Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients

Urup, T., Staunstrup, L. M., Michaelsen, S. R., Vitting-Seerup, K., Bennedbæk, M., Toft, A., Olsen, L. R., Jønson, L., Issazadeh-Navikas, S., Broholm, H., Hamerlik, P., Poulsen, H. S. & Lassen, U. N., 18 Apr 2017, In: BMC Cancer. 17, 10 p., 278.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

72 Downloads (Pure)

Computational and RNA Biology

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