Camilla Foged

Publikation

Publikationer pr. år 2002 2010 2011 2012 2013 2014 2015 2017 2018 2019 2019

• 101 Tidsskriftartikel
• 10 Poster
• 8 Review
• 7 Bidrag til bog/antologi
• 12 Mere
  • 3 Konferenceartikel
  • 2 Konferenceabstrakt til konference
  • 2 Konferenceabstrakt i tidsskrift
  • 2 Patent
  • 1 Bog
  • 1 Konferencebidrag i proceedings
  • 1 Leder

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2019

  Application of a Quality-By-Design Approach to Optimise Lipid-Polymer Hybrid Nanoparticles Loaded with a Splice-Correction Antisense Oligonucleotide: Maximising Loading and Intracellular Delivery

  Thanki, K., Papai, S., Lokras, A., Rose, F., Falkenberg, E., Franzyk, H. & Foged, C., 1 mar. 2019, I: Pharmaceutical Research. 36, 3, s. 37

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Antisense Oligonucleotide 100%
  • Antisense Oligonucleotides 83%
  • Polymers 63%
  • Nanoparticles 63%
  • Lipids 47%
  5 Citationer (Scopus)

• Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration

  Tandrup Schmidt, S., Line Olsen, C., Franzyk, H., Wørzner, K., Smith Korsholm, K., Rades, T., Andersen, P., Foged, C. & Christensen, D., jul. 2019, I: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 140, s. 29-39 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Adjuvant 100%
  • Cytotoxic T-Lymphocytes 87%
  • Vaccines 60%
  • phosphorylethanolamine 51%
  • Antigen 40%
  7 Citationer (Scopus)

  59 Downloads (Pure)

• Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles

  Thakur, A., Rose, F., Ansari, S. R., Koch, P., Martini, V., Ovesen, S. L., Quistorff, B., Maritim, S., Hyder, F., Andersen, P., Christensen, D., Mori, Y. & Foged, C., 30 aug. 2019, I: Molecular Pharmaceutics. 16, 11, s. 4725-4737 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Intrapulmonary 100%
  • Gadoteridol 94%
  • gadoteridol 92%
  • Adjuvant 67%
  • Magnetic Resonance Imaging 36%
  1 Citationer (Scopus)

• Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy

  Leng, D., Kissi, E. O., Löbmann, K., Thanki, K., Fattal, E., Rades, T., Foged, C. & Yang, M., 1 apr. 2019, I: AAPS PharmSciTech. 20, 3, s. 137

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Budesonide 100%
  • Theophylline 72%
  • Dosage Forms 68%
  • Dosage Form 62%
  • Spray 46%
  7 Citationer (Scopus)

• Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation

  Dormenval, C., Lokras, A., Cano-Garcia, G., Wadhwa, A., Thanki, K., Rose, F., Thakur, A., Franzyk, H. & Foged, C., 1 okt. 2019, I: Pharmaceutical Research. 36, 10, s. 142

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Small Interfering RNA 100%
  • Dosage Form 73%
  • Powders 72%
  • Spray 67%
  • Inhalation 67%
  12 Citationer (Scopus)

• Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model

  Jansen, M. A. A., Klausen, L. H., Thanki, K., Lyngsø, J., Skov Pedersen, J., Franzyk, H., Nielsen, H. M., van Eden, W., Dong, M., Broere, F., Foged, C. & Zeng, X., sep. 2019, I: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Intraarticular 100%
  • Small Interfering RNA 80%
  • Experimental Arthritis 69%
  • Polymers 51%
  • Nanoparticles 51%
  12 Citationer (Scopus)

• Macrophage phosphoproteome analysis reveals MINCLE-dependent and -independent mycobacterial cord factor signaling

  Hansen, M., Peltier, J., Killy, B., Amin, B., Bodendorfer, B., Härtlova, A., Uebel, S., Bosmann, M., Hofmann, J., Büttner, C., Ekici, A. B., Kuttke, M., Franzyk, H., Foged, C., Beer-Hammer, S., Schabbauer, G., Trost, M. & Lang, R., apr. 2019, I: Molecular and Cellular Proteomics. 18, 4, s. 669-685

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Cord Factors 100%
  • Trehalose 84%
  • Cord 76%
  • Macrophages 43%
  • Lectin 42%
  8 Citationer (Scopus)

• Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration

  Thanki, K., van Eetvelde, D., Geyer, A., Fraire, J., Hendrix, R., Van Eygen, H., Putteman, E., Sami, H., de Souza Carvalho-Wodarz, C., Franzyk, H., Nielsen, H. M., Braeckmans, K., Lehr, C-M., Ogris, M. & Foged, C., 28 sep. 2019, I: Journal of controlled release : official journal of the Controlled Release Society.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Silencing RNA 100%
  • Polymers 68%
  • Nanoparticles 68%
  • Small Interfering RNA 64%
  • Kinetics 55%
  15 Citationer (Scopus)

• Microfluidics-based self-assembly of peptide-loaded microgels: Effect of three dimensional (3D) printed micromixer design

  Borro, B. C., Bohr, A., Bucciarelli, S., Boetker, J. P., Foged, C., Rantanen, J. & Malmsten, M., 7 mar. 2019, I: Journal of Colloid and Interface Science. 538, s. 559-568 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Peptides 100%
  • Self assembly 99%
  • Microfluidics 80%
  • Encapsulation 52%
  • Polymyxin 44%
  12 Citationer (Scopus)

• Nebulised lipid-polymer hybrid nanoparticles for the delivery of a therapeutic anti-inflammatory microRNA to bronchial epithelial cells

  Vencken, S., Foged, C., Ramsey, J. M., Sweeney, L., Cryan, S-A., MacLoughlin, R. J. & Greene, C. M., apr. 2019, I: ERJ Open Research. 5, 2

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Polymers 100%
  • Nanoparticles 99%
  • MicroRNAs 94%
  • Anti-Inflammatory Agents 82%
  • Epithelial Cells 80%

• Preparation, Characterization, and In Vitro Evaluation of Lipidoid-Polymer Hybrid Nanoparticles for siRNA Delivery to the Cytosol

  Thanki, K., Zeng, X. & Foged, C., 2019, I: Methods in molecular biology (Clifton, N.J.). 1943, s. 141-152 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Cytosol 100%
  • Polymers 92%
  • Nanoparticles 92%
  • Small Interfering RNA 86%
  • Emulsions 48%
  7 Citationer (Scopus)

• Qualitative and quantitative analysis of the biophysical interaction of inhaled nanoparticles with pulmonary surfactant by using quartz crystal microbalance with dissipation monitoring

  Wan, F., Nylander, T., Foged, C., Yang, M., Baldursdottir, S. G. & Nielsen, H. M., 1 jun. 2019, I: Journal of Colloid and Interface Science. 545, s. 162-171 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Quartz crystal microbalances 100%
  • Qualitative Analysis 69%
  • Surface active agents 69%
  • Dissipation 69%
  • Nanoparticles 62%
  8 Citationer (Scopus)
• 2018

  Anchoring of hydrophilic coating polymers onto charged liposomes via attractive electrostatic interactions using charged tags to control the surface charge drainage properties and cellular targeting

  Andersen, P. L., Christensen, D., Franzyk, H., Foged, C. & Schmidt, S. T., 2018, (Afsendt)

  Publikation: Patent

• A strong adjuvant based on glycol-chitosan-coated lipid-polymer hybrid nanoparticles potentiates mucosal immune responses against the recombinant Chlamydia trachomatis fusion antigen CTH522

  Rose, F., Erbo Wern, J., Gavins, F., Andersen, P., Follmann, F. & Foged, C., 10 feb. 2018, I: Journal of Controlled Release. 271, s. 88-97 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • glycol-chitosan 100%
  • Mucosal Immunity 71%
  • Adjuvant 71%
  • Chlamydia trachomatis 66%
  • Polymers 51%
  19 Citationer (Scopus)

• Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization

  Thakur, A., Rodríguez-Rodríguez, C., Saatchi, K., Rose, F., Esposito, T., Nosrati, Z., Andersen, P., Christensen, D., Häfeli, U. O. & Foged, C., 30 nov. 2018, I: Frontiers in Immunology. 9, 21 s., 2825.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Tuberculosis Vaccines 100%
  • Single Photon Emission Computed Tomography Computed Tomography 90%
  • Intraepithelial Lymphocytes 89%
  • Subunit Vaccines 84%
  • Isotopes 75%
  7 Citationer (Scopus)

  26 Downloads (Pure)

• Engineering of budesonide-loaded lipid-polymer hybrid nanoparticles using a quality-by-design approach

  Leng, D., Thanki, K., Fattal, E., Foged, C. & Yang, M., 15 sep. 2018, I: International Journal of Pharmaceutics. 548, 2, s. 740-746

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Budesonide 100%
  • Propane 71%
  • Polymers 54%
  • Nanoparticles 54%
  • Lipids 40%
  13 Citationer (Scopus)

• Formulating Inhalable Dry Powders Using Two-Fluid and Three-Fluid Nozzle Spray Drying

  Leng, D., Thanki, K., Foged, C. & Yang, M., 1 dec. 2018, I: Pharmaceutical Research. 35, 12, 12 s., 247.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Budesonide 100%
  • Nozzle 71%
  • Powders 61%
  • Spray 57%
  • Mannitol 41%
  9 Citationer (Scopus)

• Formulation of RNA interference-based drugs for pulmonary delivery: challenges and opportunities

  Thanki, K., Blum, K. G., Thakur, A., Rose, F. & Foged, C., okt. 2018, I: Therapeutic Delivery. 9, 10, s. 731-749 19 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • RNAi Therapeutics 100%
  • Nucleic Acids 86%
  • RNA Interference 84%
  • Lung 47%
  • Drug 46%
  7 Citationer (Scopus)

• Immune Reactions in the Delivery of RNA Interference-Based Therapeutics: Mechanisms and Opportunities

  Thanki, K., Falkenberg, E., Gangloff, M. & Foged, C., 31 aug. 2018, Immune Effects of Biopharmaceuticals and Nanomedicine. Bawa, R., Szebeni, J. & Audette, G. (red.). Pan Stanford, 32 s.

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

• Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein

  Rodrigues, L., Raftopoulos, K. N., Tandrup Schmidt, S., Schneider, F., Dietz, H., Rades, T., Franzyk, H., Pedersen, A. E., Papadakis, C. M., Christensen, D., Winter, G., Foged, C. & Hubert, M., 10 sep. 2018, I: Journal of controlled release : official journal of the Controlled Release Society. 285, s. 12-22 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • monomycoloyl glycerol 100%
  • Chlamydia trachomatis omp1 protein 78%
  • Adjuvant 54%
  • 3,7,11,15-tetramethyl-1,2,3-hexadecanetriol 52%
  • Phytantriol 45%
  7 Citationer (Scopus)

• Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design

  de Groot, A. M., Thanki, K., Gangloff, M., Falkenberg, E., Zeng, X., van Bijnen, D. C. J., van Eden, W., Franzyk, H., Nielsen, H. M., Broere, F., Gay, N. J., Foged, C. & Sijts, A. J. A. M., 1 jun. 2018, I: Molecular Therapy - Nucleic Acids. 11, s. 159-169 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Small Interfering RNA 100%
  • Computer Simulation 68%
  • Nanoparticles 64%
  • Lipids 47%
  • Nanoparticle 35%
  12 Citationer (Scopus)

  97 Downloads (Pure)

• Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder

  Thakur, A., Ingvarsson, P. T., Schmidt, S. T., Rose, F., Andersen, P., Christensen, D. & Foged, C., 31 maj 2018, I: Vaccine. 36, 23, s. 3331-3339 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Tuberculosis Vaccines 100%
  • subunit vaccines 94%
  • Subunit Vaccines 84%
  • tuberculosis 78%
  • Powders 70%
  9 Citationer (Scopus)

• Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)

  Schmidt, S. T., Pedersen, G. K., Neustrup, M. A., Korsholm, K. S., Rades, T., Andersen, P., Foged, C. & Christensen, D., 30 apr. 2018, I: Frontiers in Immunology. 9, 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Toll-Like Receptor 3 100%
  • Poly I-C 88%
  • Subunit Vaccines 84%
  • Emulsions 75%
  • Cytotoxic T-Lymphocytes 75%
  8 Citationer (Scopus)

  44 Downloads (Pure)

• Insight into Nanoscale Network of Spray-dried Polymeric Particles: Role of Polymer Molecular Conformation

  Wan, F., Larsen, F. H., Nunes Bordallo, H., Foged, C., Rantanen, J. & Yang, M., 31 okt. 2018, I: A C S Applied Materials and Interfaces. 10, 43, s. 36686-36692

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Milk 100%
  • Conformations 94%
  • Acids 68%
  • Polymers 54%
  • Acid 26%
  6 Citationer (Scopus)

• Lipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization, immunogenicity studies, in vitro release experiments, in vivo biodistribution and efficacy studies

  Thanki, K., Thakur, A., de Groot, A. M., Geyer, A., Fraire, J., Falkenberg, E., Van Eygen, H., Putteman, E., Van Bijnen, D. C. J., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Broere, F., van Eden, W., Sijts, A. J. A. M., Ogris, M., Nielsen, H. M., Braeckmans, K., & 1 flereFoged, C., 2018.

  Publikation: Konferencebidrag › Konferenceabstrakt til konference › Forskning › peer review

• Lipid shell-enveloped polymeric nanoparticles with high integrity of lipid shells improve mucus penetration and interaction with cystic fibrosis-related bacterial biofilms

  Wan, F., Nylander, T., Klodzinska, S. N., Foged, C., Yang, M., Baldursdottir, S. G. & Mørck Nielsen, H., 4 apr. 2018, I: A C S Applied Materials and Interfaces. 10, 13, s. 10678–10687

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Biofilms 100%
  • Lipids 99%
  • Polystyrenes 85%
  • Nanoparticles 73%
  • Lipid 51%
  11 Citationer (Scopus)

• Potential mucus rheological consequences of off target siRNA loaded nanoparticle deposition in the lungs

  Katuwal, N., Loretz, B., Thanki, K., Hallbrink, M., Lehr, C-M., Foged, C., Draget, K. & Nordgård, C. T., 2018, ANNUAL TRANSACTIONS OF THE NORDIC RHEOLOGY SOCIETY. Bind 26.

  Publikation: Bidrag til bog/antologi/rapport › Konferencebidrag i proceedings › Forskning

  • Mucus 100%
  • Nanoparticles 83%
  • Small Interfering RNA 78%
  • Lung 50%
  • Pharmaceutical Preparations 25%

• Selected contributions from the 10th European Workshop on Particulate Systems, Copenhagen 19th–20th January 2017

  Foged, C., 15 sep. 2018, I: International Journal of Pharmaceutics. 548, 2, s. 729

  Publikation: Bidrag til tidsskrift › Leder

  • Education 100%
  • Nanomedicine 86%
  • Drug 83%
  • Nanoparticles 80%
  • Nucleic Acids 67%

• Temperature-Induced Self-Assembly of the Group B Streptococcus (GBS) Fusion Antigen GBS-NN

  Rose, F., Roovers, S., Fano, M., Harloff-Helleberg, S., Kirkensgaard, J. J. K., Hejnaes, K., Fischer, P. & Foged, C., 2 jul. 2018, I: Molecular Pharmaceutics. 15, s. 2584-2593 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Streptococcus agalactiae 100%
  • Secondary Structure 71%
  • Antigen 68%
  • Temperature 58%
  • Protein C 55%
  1 Citationer (Scopus)

• Unusual Self-Assembly of the Recombinant Chlamydia trachomatis Major Outer Membrane Protein-Based Fusion Antigen CTH522 Into Protein Nanoparticles

  Rose, F., Karlsen, K., Jensen, P. R., Jakobsen, R. U., Wood, G. K., Rand, K. D., Godiksen, H., Andersen, P., Follmann, F. & Foged, C., jun. 2018, I: Journal of Pharmaceutical Sciences. 107, 6, s. 1690-1700 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Chlamydia trachomatis omp1 protein 100%
  • Nanoparticles 49%
  • Antigen 46%
  • Membrane Proteins 46%
  • Antigens 35%
  1 Citationer (Scopus)
• 2017

  Adjuvants based on synthetic mycobacterial cord factor analogues: Biophysical properties of neat glycolipids and nano-self-assemblies with DDA

  Kallerup, R. S., Franzyk, H., Schiøth, M. L., Justesen, S., Martin-Bertelsen, B., Rose, F., Madsen, C. M., Christensen, D., Korsholm, K. S., Yaghmur, A. & Foged, C., 3 jul. 2017, I: Molecular Pharmaceutics. 14, 7, s. 2294-2306 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • dimethyldioctadecylammonium 100%
  • tyramine-deoxysorbitol 97%
  • Cord Factors 91%
  • Trehalose 70%
  • Adjuvant 69%
  3 Citationer (Scopus)

• Advances in combination therapy of lung cancer: Rationales, delivery technologies and dosage regimens

  Wu, L., Leng, D., Cun, D., Foged, C. & Yang, M., 28 aug. 2017, I: Journal of Controlled Release. 260, s. 78-91

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Lung Neoplasms 100%
  • Pharmaceutical 92%
  • Technology 82%
  • Drug 44%
  • Pharmacokinetics 31%
  27 Citationer (Scopus)

• ANTI-INFLAMMATORY EFFECT OF ANTI-TNF-ALPHA siRNA CATIONIC PHOSPHOROUS DENDRIMERS NANOCOMPLEXES ADMINISTERED INTRANASALLY IN A MURINE ACUTE LUNG INJURY MODEL

  Bohr, A., Tsapis, N., Andreana, I., Chamarat, A., Foged, C., Delomenie, C., Noiray, M., El Brahmi, N., Majoral, J-P., Mignani, S. & Fattal, E., 21 jun. 2017, I: Biomacromolecules. 18, 8, s. 2379–2388

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Tumor Necrosis Factor-alpha 100%
  • Dendrimers 96%
  • Small Interfering RNA 74%
  • RNA 64%
  • Dendrimer 52%
  29 Citationer (Scopus)

• Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs

  Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Nielsen, H. M., Franzyk, H. & Foged, C., 2017.

  Publikation: Konferencebidrag › Poster › Forskning

• Engineering of small interfering RNA-loaded lipidoid-poly(DL-lactic-co-glycolic acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design-based approach

  Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Van Driessche, E., Nielsen, H. M., Franzyk, H. & Foged, C., nov. 2017, I: European Journal of Pharmaceutics and Biopharmaceutics. 120, s. 22-33 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Small Interfering RNA 100%
  • Polylactic Acid-Polyglycolic Acid Copolymer 93%
  • Gene Silencing 76%
  • Nanoparticles 64%
  • Lipids 47%
  24 Citationer (Scopus)

• Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying

  Agnoletti, M., Bohr, A., Thanki, K., Wan, F., Zeng, X., Bøtker, J. P., Yang, M. & Foged, C., nov. 2017, I: European Journal of Pharmaceutics and Biopharmaceutics. 120, s. 9-21

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Microfluidics 100%
  • Spray 77%
  • Small Interfering RNA 69%
  • Powders 50%
  • Dendrimers 45%
  20 Citationer (Scopus)

• Nanoparticle compositions comprising PLGA derivatives and a lipid for delivery of drugs, in particular nucleic acids, especially siRNA

  Foged, C., Franzyk, H., Zeng, X., Nielsen, H. M. & Thanki, K., 21 sep. 2017, IPC nr. A61K31/713, A61K47/18, A61K47/34, A61K9/51, A61P25/00, A61P29/00, A61P35/00, Patentnr. WO2017158093-A1, 16 mar. 2017, Prioritetsdato 17 mar. 2016, Prioritetsnr. EP 2016-160931

  Publikation: Patent

  • Nucleic Acids 100%
  • Nanoparticles 90%
  • Small Interfering RNA 85%
  • Lipids 66%
  • Drug Delivery Systems 49%

• Quality-by-design in nanomedicine: Highly systematic optimization of lipid-polymer hybrid nanoparticles for efficacious and safe intracellular delivery of cargo siRNA

  Zeng, X., Nielsen, H. M., Franzyk, H. & Foged, C., 2017.

  Publikation: Konferencebidrag › Konferenceabstrakt til konference › Forskning

• Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy

  Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, H. M., Franzyk, H. & Foged, C., 2017.

  Publikation: Konferencebidrag › Poster › Forskning

• Systematic investigation of the role of surfactant composition and choice of oil: Design of a nanoemulsion-based adjuvant inducing concomitant humoral and CD4+ T-cell responses

  Schmidt, S. T., Neustrup, M. A., Harloff-Helleberg, S., Korsholm, K. S., Rades, T., Andersen, P., Christensen, D. & Foged, C., 1 aug. 2017, I: Pharmaceutical Research. 34, 8, s. 1716-1727 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Adjuvant 100%
  • Surface-Active Agents 84%
  • Oils 80%
  • monomycoloyl glycerol 61%
  • Emulsions 58%
  5 Citationer (Scopus)
• 2016

  Conserved molecular superlattices in a series of homologous synthetic mycobacterial cell-wall lipids forming interdigitated bilayers

  Martin-Bertelsen, B., Yaghmur, A., Franzyk, H., Justesen, S., Kirkensgaard, J. J. K. & Foged, C., 6 dec. 2016, I: Langmuir. 32, 48, s. 12693–12701 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Superlattices 100%
  • Lipids 71%
  • Glycerol 66%
  • glycerols 61%
  • Superlattice 54%
  2 Citationer (Scopus)

• Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.

  Jing, X., Foged, C., Martin-Bertelsen, B., Yaghmur, A., Knapp, K. M., Malmsten, M., Franzyk, H. & Nielsen, H. M., 6 jun. 2016, I: Molecular Pharmaceutics. 13, 6, s. 1739-1749 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Peptoids 100%
  • Peptidomimetics 81%
  • Cell-Penetrating Peptides 78%
  • Small Interfering RNA 77%
  • Peptidomimetic 67%
  10 Citationer (Scopus)

• Efficient Pulmonary Delivery of siRNA Using Lipid-Polymer Hybrid Nanoparticles (LPNs): Insights into Formulation, Transfection and In Vivo Biodistribution Using NIR-based Spatio-Temporal Tracking.

  Thanki, K., Geyer, A., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Ogris, M., Nielsen, H. M. & Foged, C., 2016.

  Publikation: Konferencebidrag › Poster › Forskning

• Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators

  Schmidt, S. T., Foged, C., Korsholm, K. S., Rades, T. & Christensen, D., 10 mar. 2016, I: Pharmaceutics. 8, 1, 22 s., 7.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Adjuvant 100%
  • Subunit Vaccines 97%
  • Liposomes 79%
  • Antigen 67%
  • Vaccines 60%
  84 Citationer (Scopus)

• Nano-self-assemblies based on synthetic analogues of mycobacterial monomycoloyl glycerol and DDA: Supramolecular structure and adjuvant efficacy

  Martin-Bertelsen, B., Korsholm, K. S., Christensen, D., Franzyk, H., Yaghmur, A. & Foged, C., 1 aug. 2016, I: Molecular Pharmaceutics. 13, 8, s. 2771-2781 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • monomycoloyl glycerol 100%
  • dimethyldioctadecylammonium 78%
  • Adjuvant 54%
  • Supramolecular Structure 46%
  • Glycerol 37%
  9 Citationer (Scopus)

• The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile

  Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, T., Andersen, P., Foged, C. & Christensen, D., 10 okt. 2016, I: Journal of controlled release : official journal of the Controlled Release Society. 239, s. 107-117 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • CD8 Antigens 100%
  • Adjuvant 89%
  • Ovalbumin 81%
  • Vaccines 54%
  • Immunization 47%
  34 Citationer (Scopus)

• Thermostable Subunit Vaccines for Pulmonary Delivery: How Close Are We?

  Foged, C., 1 maj 2016, I: Current Pharmaceutical Design. 22, 17, s. 2561-2576 16 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Subunit Vaccines 100%
  • Dosage Form 84%
  • Freezer 63%
  • Vaccines 62%
  • Adjuvant 51%
  10 Citationer (Scopus)

• Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages invitro and adjuvant activity invivo

  Huber, A., Kallerup, R. S., Korsholm, K. S., Franzyk, H., Lepenies, B., Christensen, D., Foged, C. & Lang, R., 1 aug. 2016, I: Innate Immunity. 22, 6, s. 405-418 14 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  30 Citationer (Scopus)
• 2015

  Biophysical and nanostructural properties of trehalose 6-mono and 6,6’-diesters

  Madsen, C. M., Martin-Bertelsen, B., Kallerup, R. S., Rose, F., Christensen, D., Yaghmur, A., Franzyk, H. & Foged, C., 2015. 1 s.

  Publikation: Konferencebidrag › Poster › Forskning

• Characterizing the association between antigens and adjuvants

  Jensen, M. H. & Foged, C., 2015, Subunit vaccine delivery. London, s. 413-426 14 s.

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review