Publikationer pr. år
Publikationer pr. år
Personlig profil
Kort præsentation
Computational chemist and protein modeller, with strong experience and track-record in small molecule and peptides identefication covering a variety of family targets, drug discovery and hit-to-lead optimization programes.
CV
Highly skilled and motivated computational chemist (4+ years), with special focus on CADD, homology modeling, VS, SBDD, cheminformatics, SAR and pharmacophore modeling (Ph.D. Computational Chemistry)
In depth chemistry understanding and knowledge (M.Sc. Medicinal Chemistry).
Sharp writing skills, with a proven track-record of learned and applied research skills/techniques (Published three 1st & One 2nd authorship peer-reviewed scientific articles).
Deeply enjoys working on projects with colleagues from different backgrounds e.g. pharmacology and synthetic chemistry to answer a challenging scientific problem (Completed highly interdisciplinary M.Sc. & Ph.D. projects & stayed for half a year in USA on an independent scientific research stay)
Excellent communication and presentation skills (Oral & poster presentations in international conferences)
Uddannelse (Akademiske kvalifikationer)
University of Copenhagen
Dimissionsdato: 2 maj 2018
University of Copenhagen
Dimissionsdato: 2 dec. 2015
Pharmacy, German University in Cairo
Dimissionsdato: 15 jul. 2010
Emneord
- Det Sundhedsvidenskabelige Fakultet
Fingeraftryk
Dyk ned i forskningsemnerne, hvor Mohamed A. Shehata er aktive. Disse emneetiketter kommer fra dennes persons arbejder. Sammen danner de et unikt fingerprint.
- 6 Lignende profiler
Publikation
- 5 Tidsskriftartikel
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Identification of a novel scaffold for a small molecule GPR139 receptor agonist
Nøhr, A. C., Shehata, M. A., Palmer, D., Pokhrel, R., Vallianou, M., Foster, S. R., Gentry, P. R., Gloriam, D. E. & Bräuner-Osborne, H., 1 dec. 2019, I: Scientific Reports. 9, 1, s. 3802Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site
Shehata, M. A., Jensen, A. C. N., Jespers, W., Floryan, L., Isberg, V., Andersen, K. B., Åqvist, J., Gutiérrez-de-Terán, H., Bräuner-Osborne, H. & Gloriam, D. E., 1 dec. 2017, I: Scientific Reports. 7, 9 s., 1128.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW
Jensen, A. C. N., Shehata, M. A., Hauser, A. S., Isberg, V., Mokrosinski, J., Farooqi, I. S., Pedersen, D. S., Gloriam, D. E. & Bräuner-Osborne, H., 1 jan. 2017, I: Neurochemistry International. 102, s. 105-113Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139
Shehata, M. A., Jensen, A. C. N., Lissa, D., Bisig, C., Isberg, V., Andersen, K. B., Harpsøe, K., Björkling, F., Bräuner-Osborne, H. & Gloriam, D. E., 10 nov. 2016, I: Scientific Reports. 6, s. 1-13 13 s., 36681.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Identification of the first surrogate agonists for the G protein-coupled receptor GPR132
Shehata, M. A., Christensen, H. B., Isberg, V., Pedersen, D. S., Bender, A., Bräuner-Osborne, H. & Gloriam, D. E., 2015, I: RSC Advances. 5, s. 48551-48557 7 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review